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Items: 13


Using Python for Spatially Resolved Modeling with Simmune.

Angermann BR, Meier-Schellersheim M.

Methods Mol Biol. 2019;1945:161-177. doi: 10.1007/978-1-4939-9102-0_7.


A hierarchy of affinities between cytokine receptors and the common gamma chain leads to pathway cross-talk.

Gonnord P, Angermann BR, Sadtler K, Gombos E, Chappert P, Meier-Schellersheim M, Varma R.

Sci Signal. 2018 Apr 3;11(524). pii: eaal1253. doi: 10.1126/scisignal.aal1253.


Distinct NF-κB and MAPK Activation Thresholds Uncouple Steady-State Microbe Sensing from Anti-pathogen Inflammatory Responses.

Gottschalk RA, Martins AJ, Angermann BR, Dutta B, Ng CE, Uderhardt S, Tsang JS, Fraser ID, Meier-Schellersheim M, Germain RN.

Cell Syst. 2016 Jun 22;2(6):378-90. doi: 10.1016/j.cels.2016.04.016. Epub 2016 May 26.


Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing.

Manes NP, Angermann BR, Koppenol-Raab M, An E, Sjoelund VH, Sun J, Ishii M, Germain RN, Meier-Schellersheim M, Nita-Lazar A.

Mol Cell Proteomics. 2015 Oct;14(10):2661-81. doi: 10.1074/mcp.M115.048918. Epub 2015 Jul 21.


NetworkViewer: visualizing biochemical reaction networks with embedded rendering of molecular interaction rules.

Cheng HC, Angermann BR, Zhang F, Meier-Schellersheim M.

BMC Syst Biol. 2014 Jun 16;8:70. doi: 10.1186/1752-0509-8-70.


Inflammation-induced interstitial migration of effector CD4⁺ T cells is dependent on integrin αV.

Overstreet MG, Gaylo A, Angermann BR, Hughson A, Hyun YM, Lambert K, Acharya M, Billroth-Maclurg AC, Rosenberg AF, Topham DJ, Yagita H, Kim M, Lacy-Hulbert A, Meier-Schellersheim M, Fowell DJ.

Nat Immunol. 2013 Sep;14(9):949-58. doi: 10.1038/ni.2682. Epub 2013 Aug 11.


High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance.

Petrovas C, Yamamoto T, Price DA, Rao SS, Klatt NR, Brenchley JM, Douek DC, Gostick E, Angermann BR, Grossman Z, Macallan DC, Meier-Schellersheim M, Koup RA.

J Virol. 2013 Sep;87(17):9836-44. doi: 10.1128/JVI.01001-13. Epub 2013 Jul 3.


Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.

Lämmermann T, Afonso PV, Angermann BR, Wang JM, Kastenmüller W, Parent CA, Germain RN.

Nature. 2013 Jun 20;498(7454):371-5. doi: 10.1038/nature12175. Epub 2013 May 26.


The Simmune Modeler visual interface for creating signaling networks based on bi-molecular interactions.

Zhang F, Angermann BR, Meier-Schellersheim M.

Bioinformatics. 2013 May 1;29(9):1229-30. doi: 10.1093/bioinformatics/btt134. Epub 2013 Mar 17.


Recent progress using systems biology approaches to better understand molecular mechanisms of immunity.

Gottschalk RA, Martins AJ, Sjoelund V, Angermann BR, Lin B, Germain RN.

Semin Immunol. 2013 Oct 31;25(3):201-8. doi: 10.1016/j.smim.2012.11.002. Epub 2012 Dec 11. Review.


Computational modeling of cellular signaling processes embedded into dynamic spatial contexts.

Angermann BR, Klauschen F, Garcia AD, Prustel T, Zhang F, Germain RN, Meier-Schellersheim M.

Nat Methods. 2012 Jan 29;9(3):283-9. doi: 10.1038/nmeth.1861.


Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses.

Gaucher D, Therrien R, Kettaf N, Angermann BR, Boucher G, Filali-Mouhim A, Moser JM, Mehta RS, Drake DR 3rd, Castro E, Akondy R, Rinfret A, Yassine-Diab B, Said EA, Chouikh Y, Cameron MJ, Clum R, Kelvin D, Somogyi R, Greller LD, Balderas RS, Wilkinson P, Pantaleo G, Tartaglia J, Haddad EK, Sékaly RP.

J Exp Med. 2008 Dec 22;205(13):3119-31. doi: 10.1084/jem.20082292. Epub 2008 Dec 1.


Understanding diseases by mouse click: the promise and potential of computational approaches in Systems Biology.

Klauschen F, Angermann BR, Meier-Schellersheim M.

Clin Exp Immunol. 2007 Sep;149(3):424-9. Epub 2007 Jul 30. Review.

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