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Items: 29


Nuclear Pore Complexes Are Key Regulators of Oligodendrocyte Differentiation and Function.

Raices M, D'Angelo MA.

Neuron. 2019 May 8;102(3):509-511. doi: 10.1016/j.neuron.2019.04.025.


Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis.

Borlido J, Sakuma S, Raices M, Carrette F, Tinoco R, Bradley LM, D'Angelo MA.

Nat Immunol. 2018 Jun;19(6):594-605. doi: 10.1038/s41590-018-0103-5. Epub 2018 May 7.


Nup62-mediated nuclear import of p63 in squamous cell carcinoma.

Borlido J, D'Angelo MA.

EMBO Rep. 2018 Jan;19(1):3-4. doi: 10.15252/embr.201745497. Epub 2017 Dec 18. No abstract available.


Nuclear pore complexes as hubs for gene regulation.

D'Angelo MA.

Nucleus. 2018 Jan 1;9(1):142-148. doi: 10.1080/19491034.2017.1395542.


Global Assessment of Dengue Virus-Specific CD4+ T Cell Responses in Dengue-Endemic Areas.

Grifoni A, Angelo MA, Lopez B, O'Rourke PH, Sidney J, Cerpas C, Balmaseda A, Silveira CGT, Maestri A, Costa PR, Durbin AP, Diehl SA, Phillips E, Mallal S, De Silva AD, Nchinda G, Nkenfou C, Collins MH, de Silva AM, Lim MQ, Macary PA, Tatullo F, Solomon T, Satchidanandam V, Desai A, Ravi V, Coloma J, Turtle L, Rivino L, Kallas EG, Peters B, Harris E, Sette A, Weiskopf D.

Front Immunol. 2017 Oct 13;8:1309. doi: 10.3389/fimmu.2017.01309. eCollection 2017.


Nuclear Pores Regulate Muscle Development and Maintenance by Assembling a Localized Mef2C Complex.

Raices M, Bukata L, Sakuma S, Borlido J, Hernandez LS, Hart DO, D'Angelo MA.

Dev Cell. 2017 Jun 5;41(5):540-554.e7. doi: 10.1016/j.devcel.2017.05.007.


The roles of the nuclear pore complex in cellular dysfunction, aging and disease.

Sakuma S, D'Angelo MA.

Semin Cell Dev Biol. 2017 Aug;68:72-84. doi: 10.1016/j.semcdb.2017.05.006. Epub 2017 May 12. Review.


Nuclear pore complexes and regulation of gene expression.

Raices M, D'Angelo MA.

Curr Opin Cell Biol. 2017 Jun;46:26-32. doi: 10.1016/ Epub 2017 Jan 11. Review.


Human CD4+ T Cell Responses to an Attenuated Tetravalent Dengue Vaccine Parallel Those Induced by Natural Infection in Magnitude, HLA Restriction, and Antigen Specificity.

Angelo MA, Grifoni A, O'Rourke PH, Sidney J, Paul S, Peters B, de Silva AD, Phillips E, Mallal S, Diehl SA, Kirkpatrick BD, Whitehead SS, Durbin AP, Sette A, Weiskopf D.

J Virol. 2017 Feb 14;91(5). pii: e02147-16. doi: 10.1128/JVI.02147-16. Print 2017 Mar 1.


HLA-DRB1 Alleles Are Associated With Different Magnitudes of Dengue Virus-Specific CD4+ T-Cell Responses.

Weiskopf D, Angelo MA, Grifoni A, O'Rourke PH, Sidney J, Paul S, De Silva AD, Phillips E, Mallal S, Premawansa S, Premawansa G, Wijewickrama A, Peters B, Sette A.

J Infect Dis. 2016 Oct 1;214(7):1117-24. doi: 10.1093/infdis/jiw309. Epub 2016 Jul 20.


Immunodominant Dengue Virus-Specific CD8+ T Cell Responses Are Associated with a Memory PD-1+ Phenotype.

de Alwis R, Bangs DJ, Angelo MA, Cerpas C, Fernando A, Sidney J, Peters B, Gresh L, Balmaseda A, de Silva AD, Harris E, Sette A, Weiskopf D.

J Virol. 2016 Apr 14;90(9):4771-4779. doi: 10.1128/JVI.02892-15. Print 2016 May.


Human CD8+ T-Cell Responses Against the 4 Dengue Virus Serotypes Are Associated With Distinct Patterns of Protein Targets.

Weiskopf D, Cerpas C, Angelo MA, Bangs DJ, Sidney J, Paul S, Peters B, Sanches FP, Silvera CG, Costa PR, Kallas EG, Gresh L, de Silva AD, Balmaseda A, Harris E, Sette A.

J Infect Dis. 2015 Dec 1;212(11):1743-51. doi: 10.1093/infdis/jiv289. Epub 2015 May 15.


The human CD8+ T cell responses induced by a live attenuated tetravalent dengue vaccine are directed against highly conserved epitopes.

Weiskopf D, Angelo MA, Bangs DJ, Sidney J, Paul S, Peters B, de Silva AD, Lindow JC, Diehl SA, Whitehead S, Durbin A, Kirkpatrick B, Sette A.

J Virol. 2015 Jan;89(1):120-8. doi: 10.1128/JVI.02129-14. Epub 2014 Oct 15.


Immunodominance changes as a function of the infecting dengue virus serotype and primary versus secondary infection.

Weiskopf D, Angelo MA, Sidney J, Peters B, Shresta S, Sette A.

J Virol. 2014 Oct;88(19):11383-94. doi: 10.1128/JVI.01108-14. Epub 2014 Jul 23.


Nup62: a novel regulator of centrosome integrity and function.

Borlido J, D'Angelo MA.

Cell Cycle. 2014;13(1):14. doi: 10.4161/cc.27299. Epub 2013 Nov 22. No abstract available.


HLA class I alleles are associated with peptide-binding repertoires of different size, affinity, and immunogenicity.

Paul S, Weiskopf D, Angelo MA, Sidney J, Peters B, Sette A.

J Immunol. 2013 Dec 15;191(12):5831-9. doi: 10.4049/jimmunol.1302101. Epub 2013 Nov 4.


Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells.

Weiskopf D, Angelo MA, de Azeredo EL, Sidney J, Greenbaum JA, Fernando AN, Broadwater A, Kolla RV, De Silva AD, de Silva AM, Mattia KA, Doranz BJ, Grey HM, Shresta S, Peters B, Sette A.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):E2046-53. doi: 10.1073/pnas.1305227110. Epub 2013 Apr 11.


Nuclear pore complexes in the maintenance of genome integrity.

Bukata L, Parker SL, D'Angelo MA.

Curr Opin Cell Biol. 2013 Jun;25(3):378-86. doi: 10.1016/ Epub 2013 Apr 6. Review.


Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions.

Raices M, D'Angelo MA.

Nat Rev Mol Cell Biol. 2012 Nov;13(11):687-99. doi: 10.1038/nrm3461. Review.


A change in nuclear pore complex composition regulates cell differentiation.

D'Angelo MA, Gomez-Cavazos JS, Mei A, Lackner DH, Hetzer MW.

Dev Cell. 2012 Feb 14;22(2):446-58. doi: 10.1016/j.devcel.2011.11.021. Epub 2012 Jan 19.


Insights into HLA-restricted T cell responses in a novel mouse model of dengue virus infection point toward new implications for vaccine design.

Weiskopf D, Yauch LE, Angelo MA, John DV, Greenbaum JA, Sidney J, Kolla RV, De Silva AD, de Silva AM, Grey H, Peters B, Shresta S, Sette A.

J Immunol. 2011 Oct 15;187(8):4268-79. doi: 10.4049/jimmunol.1101970. Epub 2011 Sep 14.


Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells.

D'Angelo MA, Raices M, Panowski SH, Hetzer MW.

Cell. 2009 Jan 23;136(2):284-95. doi: 10.1016/j.cell.2008.11.037.


Structure, dynamics and function of nuclear pore complexes.

D'Angelo MA, Hetzer MW.

Trends Cell Biol. 2008 Oct;18(10):456-66. doi: 10.1016/j.tcb.2008.07.009. Epub 2008 Sep 9. Review.


Adenovirus core protein pVII is translocated into the nucleus by multiple import receptor pathways.

Wodrich H, Cassany A, D'Angelo MA, Guan T, Nemerow G, Gerace L.

J Virol. 2006 Oct;80(19):9608-18.


Nuclear pores form de novo from both sides of the nuclear envelope.

D'Angelo MA, Anderson DJ, Richard E, Hetzer MW.

Science. 2006 Apr 21;312(5772):440-3.


The role of the nuclear envelope in cellular organization.

D'Angelo MA, Hetzer MW.

Cell Mol Life Sci. 2006 Feb;63(3):316-32. Review.


Cyclic nucleotide specific phosphodiesterases of the kinetoplastida: a unified nomenclature.

Kunz S, Beavo JA, D'Angelo MA, Flawia MM, Francis SH, Johner A, Laxman S, Oberholzer M, Rascon A, Shakur Y, Wentzinger L, Zoraghi R, Seebeck T.

Mol Biochem Parasitol. 2006 Jan;145(1):133-5. Epub 2005 Oct 21. No abstract available.


Identification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi.

D'Angelo MA, Sanguineti S, Reece JM, Birnbaumer L, Torres HN, Flawiá MM.

Biochem J. 2004 Feb 15;378(Pt 1):63-72.


A novel calcium-stimulated adenylyl cyclase from Trypanosoma cruzi, which interacts with the structural flagellar protein paraflagellar rod.

D'Angelo MA, Montagna AE, Sanguineti S, Torres HN, Flawiá MM.

J Biol Chem. 2002 Sep 20;277(38):35025-34. Epub 2002 Jul 16.

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