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Items: 40

1.

A pathway for isethionate dissimilation in Bacillus krulwichiae.

Tong Y, Wei Y, Hu Y, Ang EL, Zhao H, Zhang Y.

Appl Environ Microbiol. 2019 May 24. pii: AEM.00793-19. doi: 10.1128/AEM.00793-19. [Epub ahead of print]

PMID:
31126948
2.

Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacterium Bifidobacterium kashiwanohense.

Zhou Y, Wei Y, Nanjaraj Urs AN, Lin L, Xu T, Hu Y, Ang EL, Zhao H, Yuchi Z, Zhang Y.

Biosci Rep. 2019 Jun 20;39(6). pii: BSR20190715. doi: 10.1042/BSR20190715. Print 2019 Jun 28.

PMID:
31123167
3.

Biochemical and structural investigation of taurine:2-oxoglutarate aminotransferase from Bifidobacterium kashiwanohense.

Li M, Wei Y, Yin J, Lin L, Zhou Y, Hua G, Cao P, Ang EL, Zhao H, Yuchi Z, Zhang Y.

Biochem J. 2019 Jun 11;476(11):1605-1619. doi: 10.1042/BCJ20190206.

PMID:
31088892
4.

Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria.

Xing M, Wei Y, Zhou Y, Zhang J, Lin L, Hu Y, Hua G, N Nanjaraj Urs A, Liu D, Wang F, Guo C, Tong Y, Li M, Liu Y, Ang EL, Zhao H, Yuchi Z, Zhang Y.

Nat Commun. 2019 Apr 8;10(1):1609. doi: 10.1038/s41467-019-09618-8.

5.

Delta Integration CRISPR-Cas (Di-CRISPR) in Saccharomyces cerevisiae.

Shi S, Liang Y, Ang EL, Zhao H.

Methods Mol Biol. 2019;1927:73-91. doi: 10.1007/978-1-4939-9142-6_6.

PMID:
30788786
6.

Biochemical and structural investigation of sulfoacetaldehyde reductase from Klebsiella oxytoca.

Zhou Y, Wei Y, Lin L, Xu T, Ang EL, Zhao H, Yuchi Z, Zhang Y.

Biochem J. 2019 Feb 28;476(4):733-746. doi: 10.1042/BCJ20190005.

PMID:
30718306
7.

Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole.

Liu D, Wei Y, Liu X, Zhou Y, Jiang L, Yin J, Wang F, Hu Y, Nanjaraj Urs AN, Liu Y, Ang EL, Zhao S, Zhao H, Zhang Y.

Nat Commun. 2018 Oct 11;9(1):4224. doi: 10.1038/s41467-018-06627-x.

8.

A coupled chlorinase-fluorinase system with a high efficiency of trans-halogenation and a shared substrate tolerance.

Sun H, Zhao H, Ang EL.

Chem Commun (Camb). 2018 Aug 21;54(68):9458-9461. doi: 10.1039/c8cc04436h.

PMID:
30083673
9.

Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR-Cas9 Activation.

Lim YH, Wong FT, Yeo WL, Ching KC, Lim YW, Heng E, Chen S, Tsai DJ, Lauderdale TL, Shia KS, Ho YS, Hoon S, Ang EL, Zhang MM, Zhao H.

Chembiochem. 2018 May 25. doi: 10.1002/cbic.201800266. [Epub ahead of print]

PMID:
29799651
10.

Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes.

Tapsin S, Sun M, Shen Y, Zhang H, Lim XN, Susanto TT, Yang SL, Zeng GS, Lee J, Lezhava A, Ang EL, Zhang LH, Wang Y, Zhao H, Nagarajan N, Wan Y.

Nat Commun. 2018 Mar 29;9(1):1289. doi: 10.1038/s41467-018-03675-1.

11.

In vivo biosensors: mechanisms, development, and applications.

Shi S, Ang EL, Zhao H.

J Ind Microbiol Biotechnol. 2018 Jul;45(7):491-516. doi: 10.1007/s10295-018-2004-x. Epub 2018 Jan 29.

PMID:
29380152
12.

Recent developments in the application of P450 based biocatalysts.

Wei Y, Ang EL, Zhao H.

Curr Opin Chem Biol. 2018 Apr;43:1-7. doi: 10.1016/j.cbpa.2017.08.006. Epub 2017 Oct 27. Review.

PMID:
29100098
13.

Discovery and engineering of a 1-butanol biosensor in Saccharomyces cerevisiae.

Shi S, Choi YW, Zhao H, Tan MH, Ang EL.

Bioresour Technol. 2017 Dec;245(Pt B):1343-1351. doi: 10.1016/j.biortech.2017.06.114. Epub 2017 Jun 23.

PMID:
28712783
14.

Biocatalysis for the synthesis of pharmaceuticals and pharmaceutical intermediates.

Sun H, Zhang H, Ang EL, Zhao H.

Bioorg Med Chem. 2018 Apr 1;26(7):1275-1284. doi: 10.1016/j.bmc.2017.06.043. Epub 2017 Jun 28. Review.

PMID:
28709846
15.

Evaluation of Corneal Endothelial Cell Loss After Uncomplicated Phacoemulsification Cataract Surgery With Intracameral Phenylephrine.

Teoh LS, Foo SW, Mansurali VN, Ang EL, Md Noh UK, Bastion MC.

Asia Pac J Ophthalmol (Phila). 2017 Jul-Aug;6(4):318-325. doi: 10.22608/APO.2016206. Epub 2017 Jun 1.

PMID:
28581284
16.

CRISPR-Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters.

Zhang MM, Wong FT, Wang Y, Luo S, Lim YH, Heng E, Yeo WL, Cobb RE, Enghiad B, Ang EL, Zhao H.

Nat Chem Biol. 2017 Apr 10. doi: 10.1038/nchembio.2341. [Epub ahead of print]

17.

Twin-primer non-enzymatic DNA assembly: an efficient and accurate multi-part DNA assembly method.

Liang J, Liu Z, Low XZ, Ang EL, Zhao H.

Nucleic Acids Res. 2017 Jun 20;45(11):e94. doi: 10.1093/nar/gkx132.

18.

Using natural products for drug discovery: the impact of the genomics era.

Zhang MM, Qiao Y, Ang EL, Zhao H.

Expert Opin Drug Discov. 2017 May;12(5):475-487. doi: 10.1080/17460441.2017.1303478. Epub 2017 Mar 14. Review.

19.

Probing the molecular determinants of fluorinase specificity.

Yeo WL, Chew X, Smith DJ, Chan KP, Sun H, Zhao H, Lim YH, Ang EL.

Chem Commun (Camb). 2017 Feb 23;53(17):2559-2562. doi: 10.1039/c6cc09213f.

PMID:
28184383
20.

A New Era of Genome Integration-Simply Cut and Paste!

Liu Z, Liang Y, Ang EL, Zhao H.

ACS Synth Biol. 2017 Apr 21;6(4):601-609. doi: 10.1021/acssynbio.6b00331. Epub 2017 Jan 24. Review.

PMID:
28073246
21.

Directed Evolution of a Fluorinase for Improved Fluorination Efficiency with a Non-native Substrate.

Sun H, Yeo WL, Lim YH, Chew X, Smith DJ, Xue B, Chan KP, Robinson RC, Robins EG, Zhao H, Ang EL.

Angew Chem Int Ed Engl. 2016 Nov 7;55(46):14277-14280. doi: 10.1002/anie.201606722. Epub 2016 Oct 14.

PMID:
27739177
22.

A step through the looking glass.

Liang Y, Ang EL, Zhao H.

Sci China Life Sci. 2016 Sep;59(9):979-80. doi: 10.1007/s11427-016-0170-6. Epub 2016 Jun 27. No abstract available.

PMID:
27349997
23.

Metabolic engineering of a synergistic pathway for n-butanol production in Saccharomyces cerevisiae.

Shi S, Si T, Liu Z, Zhang H, Ang EL, Zhao H.

Sci Rep. 2016 May 10;6:25675. doi: 10.1038/srep25675.

24.

Engineering microbial hosts for production of bacterial natural products.

Zhang MM, Wang Y, Ang EL, Zhao H.

Nat Prod Rep. 2016 Aug 27;33(8):963-87. doi: 10.1039/c6np00017g. Epub 2016 Apr 13. Review.

25.

A highly efficient single-step, markerless strategy for multi-copy chromosomal integration of large biochemical pathways in Saccharomyces cerevisiae.

Shi S, Liang Y, Zhang MM, Ang EL, Zhao H.

Metab Eng. 2016 Jan;33:19-27. doi: 10.1016/j.ymben.2015.10.011. Epub 2015 Nov 4.

PMID:
26546089
26.

Recent advances in combinatorial biosynthesis for drug discovery.

Sun H, Liu Z, Zhao H, Ang EL.

Drug Des Devel Ther. 2015 Feb 12;9:823-33. doi: 10.2147/DDDT.S63023. eCollection 2015. Review.

27.

Engineered pentafunctional minicellulosome for simultaneous saccharification and ethanol fermentation in Saccharomyces cerevisiae.

Liang Y, Si T, Ang EL, Zhao H.

Appl Environ Microbiol. 2014 Nov;80(21):6677-84. doi: 10.1128/AEM.02070-14. Epub 2014 Aug 22.

28.

Urease activity represents an alternative pathway for Mycobacterium tuberculosis nitrogen metabolism.

Lin W, Mathys V, Ang EL, Koh VH, Martínez Gómez JM, Ang ML, Zainul Rahim SZ, Tan MP, Pethe K, Alonso S.

Infect Immun. 2012 Aug;80(8):2771-9. doi: 10.1128/IAI.06195-11. Epub 2012 May 29.

29.

Duodenal tuberculosis presenting as gastric outlet obstruction: A case report.

Flores HB, Zano F, Ang EL, Estanislao N.

World J Gastrointest Endosc. 2011 Jan 16;3(1):16-9. doi: 10.4253/wjge.v3.i1.16.

30.

Primary carcinoid tumour of the liver in a young Filipino female.

Holgado-Galicia MV, Nomorosa KM, Ang EL, Lantion-Ang FL.

BMJ Case Rep. 2011 Feb 14;2011. pii: bcr1020103419. doi: 10.1136/bcr.10.2010.3419.

31.

Directed evolution of aniline dioxygenase for enhanced bioremediation of aromatic amines.

Ang EL, Obbard JP, Zhao H.

Appl Microbiol Biotechnol. 2009 Jan;81(6):1063-70. doi: 10.1007/s00253-008-1710-0. Epub 2008 Sep 24.

PMID:
18813921
32.

Improvements in quality of care resulting from a formal multidisciplinary tumour clinic in the management of high-grade glioma.

Back MF, Ang EL, Ng WH, See SJ, Lim CC, Tay LL, Yeo TT.

Ann Acad Med Singapore. 2007 May;36(5):347-51.

33.

Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy.

Back MF, Ang EL, Ng WH, See SJ, Lim CC, Chan SP, Yeo TT.

Ann Acad Med Singapore. 2007 May;36(5):338-42.

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37.

Severe vincristine neurotoxicity with concomitant use of itraconazole.

Ariffin H, Omar KZ, Ang EL, Shekhar K.

J Paediatr Child Health. 2003 Nov;39(8):638-9. No abstract available.

PMID:
14629538
38.

Effects of a meal on hemodynamic function at rest and during exercise in patients with hypertrophic cardiomyopathy.

Gilligan DM, Chan WL, Ang EL, Oakley CM.

J Am Coll Cardiol. 1991 Aug;18(2):429-36.

39.

Placebo controlled trial of xamoterol versus digoxin in chronic atrial fibrillation.

Ang EL, Chan WL, Cleland JG, Moore D, Krikler SJ, Alexander ND, Oakley CM.

Br Heart J. 1990 Oct;64(4):256-60.

40.

Effect of preload change on resting and exercise cardiac performance in hypertrophic cardiomyopathy.

Chan WL, Gilligan DM, Ang EL, Oakley CM.

Am J Cardiol. 1990 Sep 15;66(7):746-51.

PMID:
2399894

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