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Time will tell: Circadian clock dysregulation in triple negative breast cancer.

Rida P, Syed MI, Aneja R.

Front Biosci (Schol Ed). 2019 Mar 1;11:178-192.


Targeting risk factors for reducing the racially disparate burden in breast cancer.

Wright N, Akinyemiju T, Subhedar P, Rida P, Aneja R.

Front Biosci (Schol Ed). 2019 Mar 1;11:136-160.


The persisting puzzle of racial disparity in triple negative breast cancer: looking through a new lens.

Garlapati C, Joshi S, Sahoo B, Kapoor S, Aneja R.

Front Biosci (Schol Ed). 2019 Mar 1;11:75-88.


Pharmacokinetic stability of macrocyclic peptide triazole HIV-1 inactivators alone and in liposomes.

Aneja R, Grigoletto A, Nangarlia A, Rashad AA, Wrenn S, Jacobson JM, Pasut G, Chaiken I.

J Pept Sci. 2019 Feb 27:e3155. doi: 10.1002/psc.3155. [Epub ahead of print]


The molecular mechanisms underlying reduced E-cadherin expression in invasive ductal carcinoma of the breast: high throughput analysis of large cohorts.

Alsaleem M, Toss MS, Joseph C, Aleskandarany M, Kurozumi S, Alshankyty I, Ogden A, Rida PCG, Ellis IO, Aneja R, Green AR, Mongan NP, Rakha EA.

Mod Pathol. 2019 Feb 13. doi: 10.1038/s41379-019-0209-9. [Epub ahead of print]


ROS- and HIF1α-dependent IGFBP3 upregulation blocks IGF1 survival signaling and thereby mediates high-glucose-induced cardiomyocyte apoptosis.

Huang YT, Liu CH, Yang YC, Aneja R, Wen SY, Huang CY, Kuo WW.

J Cell Physiol. 2019 Jan 19. doi: 10.1002/jcp.28034. [Epub ahead of print]


Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience.

Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, Han Y, Easley KA, Knezevic A, Dai T, Paden M, Carcillo JA; Thrombocytopenia-Associated Multiple Organ Failure (TAMOF) Network Study Group.

Crit Care Med. 2019 Mar;47(3):e173-e181. doi: 10.1097/CCM.0000000000003559.


Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells.

Mariappan A, Soni K, Schorpp K, Zhao F, Minakar A, Zheng X, Mandad S, Macheleidt I, Ramani A, Kubelka T, Dawidowski M, Golfmann K, Wason A, Yang C, Simons J, Schmalz HG, Hyman AA, Aneja R, Ullrich R, Urlaub H, Odenthal M, Büttner R, Li H, Sattler M, Hadian K, Gopalakrishnan J.

EMBO J. 2019 Jan 15;38(2). pii: e99876. doi: 10.15252/embj.201899876. Epub 2018 Dec 10.


Comparing breast biomarker status between routine immunohistochemistry and FISH studies and Oncotype DX testing, a study of 610 cases.

Neely C, You S, Mendoza PM, Aneja R, Sahin AA, Li X.

Breast J. 2018 Nov;24(6):889-893. doi: 10.1111/tbj.13110. Epub 2018 Sep 19.


Pkcδ Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products (Ages).

Yang YC, Tsai CY, Chen CL, Kuo CH, Hou CW, Cheng SY, Aneja R, Huang CY, Kuo WW.

Aging Dis. 2018 Aug 1;9(4):647-663. doi: 10.14336/AD.2017.0924. eCollection 2018 Aug.


Panoptic Overview of Triple-Negative Breast Cancer in Nigeria: Current Challenges and Promising Global Initiatives.

Wright N, Rida P, Rakha E, Agboola A, Aneja R.

J Glob Oncol. 2018 Jul;4:1-20. doi: 10.1200/JGO.17.00116.


Dietary Cellulose Supplementation Modulates the Immune Response in a Murine Endotoxemia Model.

Di Caro V, Cummings JL, Alcamo AM, Piganelli JD, Clark RSB, Morowitz MJ, Aneja RK.

Shock. 2019 Apr;51(4):526-534. doi: 10.1097/SHK.0000000000001180.


Lack of Benefit on Brain Edema, Blood-Brain Barrier Permeability, or Cognitive Outcome in Global Inducible High Mobility Group Box 1 Knockout Mice Despite Tissue Sparing after Experimental Traumatic Brain Injury.

Aneja RK, Alcamo AM, Cummings J, Vagni V, Feldman K, Wang Q, Dixon CE, Billiar TR, Kochanek PM.

J Neurotrauma. 2019 Jan 15;36(2):360-369. doi: 10.1089/neu.2018.5664. Epub 2018 Sep 5.


Presenting predictors and temporal trends of treatment-related outcomes in diabetic ketoacidosis.

Horvat CM, Ismail HM, Au AK, Garibaldi L, Siripong N, Kantawala S, Aneja RK, Hupp DS, Kochanek PM, Clark RS.

Pediatr Diabetes. 2018 Aug;19(5):985-992. doi: 10.1111/pedi.12663. Epub 2018 Apr 26.


Prognostic significance of tumor-infiltrating lymphocytes in ductal carcinoma in situ of the breast.

Toss MS, Miligy I, Al-Kawaz A, Alsleem M, Khout H, Rida PC, Aneja R, Green AR, Ellis IO, Rakha EA.

Mod Pathol. 2018 Aug;31(8):1226-1236. doi: 10.1038/s41379-018-0040-8. Epub 2018 Mar 20.


Pharmacokinetic-pharmacodynamic correlations in the development of ginger extract as an anticancer agent.

Mukkavilli R, Yang C, Tanwar RS, Saxena R, Gundala SR, Zhang Y, Ghareeb A, Floyd SD, Vangala S, Kuo WW, Rida PCG, Aneja R.

Sci Rep. 2018 Feb 14;8(1):3056. doi: 10.1038/s41598-018-21125-2.


First international TNBC conference meeting report.

Rida P, Ogden A, Ellis IO, Varga Z, Wolff AC, Traina TA, Hatzis C, Palmer JR, Ambrosone CB, Lehmann BD, Nanda R, Montgomery Rice V, Brawley OW, Torres MA, Rakha E, Aneja R.

Breast Cancer Res Treat. 2018 Jun;169(3):407-412. doi: 10.1007/s10549-018-4692-3. Epub 2018 Feb 8.


Pediatric Sepsis Update: How Are Children Different?

Emr BM, Alcamo AM, Carcillo JA, Aneja RK, Mollen KP.

Surg Infect (Larchmt). 2018 Feb/Mar;19(2):176-183. doi: 10.1089/sur.2017.316. Epub 2018 Feb 2. Review.


Diallyl trisulfide suppresses doxorubicin-induced cardiomyocyte apoptosis by inhibiting MAPK/NF-κB signaling through attenuation of ROS generation.

Wen SY, Tsai CY, Pai PY, Chen YW, Yang YC, Aneja R, Huang CY, Kuo WW.

Environ Toxicol. 2018 Jan;33(1):93-103. doi: 10.1002/tox.22500. Epub 2017 Oct 31.


Rationale for Adjunctive Therapies for Pediatric Sepsis Induced Multiple Organ Failure.

Podd BS, Simon DW, Lopez S, Nowalk A, Aneja R, Carcillo JA.

Pediatr Clin North Am. 2017 Oct;64(5):1071-1088. doi: 10.1016/j.pcl.2017.06.007. Epub 2017 Aug 18. Review.


Galangin suppresses H2 O2 -induced aging in human dermal fibroblasts.

Wen SY, Chen JY, Weng YS, Aneja R, Chen CJ, Huang CY, Kuo WW.

Environ Toxicol. 2017 Dec;32(12):2419-2427. doi: 10.1002/tox.22455. Epub 2017 Aug 18.


Rho-GTPase activating-protein 18: a biomarker associated with good prognosis in invasive breast cancer.

Aleskandarany MA, Sonbul S, Surridge R, Mukherjee A, Caldas C, Diez-Rodriguez M, Ashankyty I, Albrahim KI, Elmouna AM, Aneja R, Martin SG, Ellis IO, Green AR, Rakha EA.

Br J Cancer. 2017 Oct 10;117(8):1176-1184. doi: 10.1038/bjc.2017.261. Epub 2017 Aug 22.


50 years on … the discovery of tubulin continues to advance cancer treatment.

Crasta K, Aneja R.

Endocr Relat Cancer. 2017 Sep;24(9):E3-E5. doi: 10.1530/ERC-17-0273. No abstract available.


Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring.

Rashad AA, Acharya K, Haftl A, Aneja R, Dick A, Holmes AP, Chaiken I.

Org Biomol Chem. 2017 Sep 26;15(37):7770-7782. doi: 10.1039/c7ob01448a.


The American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock: Executive Summary.

Davis AL, Carcillo JA, Aneja RK, Deymann AJ, Lin JC, Nguyen TC, Okhuysen-Cawley RS, Relvas MS, Rozenfeld RA, Skippen PW, Stojadinovic BJ, Williams EA, Yeh TS, Balamuth F, Brierley J, de Caen AR, Cheifetz IM, Choong K, Conway E Jr, Cornell T, Doctor A, Dugas MA, Feldman JD, Fitzgerald JC, Flori HR, Fortenberry JD, Graciano AL, Greenwald BM, Hall MW, Han YY, Hernan LJ, Irazuzta JE, Iselin E, van der Jagt EW, Jeffries HE, Kache S, Katyal C, Kissoon N, Kon AA, Kutko MC, MacLaren G, Maul T, Mehta R, Odetola F, Parbuoni K, Paul R, Peters MJ, Ranjit S, Reuter-Rice KE, Schnitzler EJ, Scott HF, Torres A Jr, Weingarten-Abrams J, Weiss SL, Zimmerman JJ, Zuckerberg AL.

Pediatr Crit Care Med. 2017 Sep;18(9):884-890. doi: 10.1097/PCC.0000000000001259. No abstract available.


Novel immunohistochemistry-based signatures to predict metastatic site of triple-negative breast cancers.

Klimov S, Rida PC, Aleskandarany MA, Green AR, Ellis IO, Janssen EA, Rakha EA, Aneja R.

Br J Cancer. 2017 Sep 5;117(6):826-834. doi: 10.1038/bjc.2017.224. Epub 2017 Jul 18.


Minocycline Attenuates High Mobility Group Box 1 Translocation, Microglial Activation, and Thalamic Neurodegeneration after Traumatic Brain Injury in Post-Natal Day 17 Rats.

Simon DW, Aneja RK, Alexander H, Bell MJ, Bayır H, Kochanek PM, Clark RSB.

J Neurotrauma. 2018 Jan 1;35(1):130-138. doi: 10.1089/neu.2017.5093. Epub 2017 Aug 22.


Detecting and Quantifying pADPr In Vivo.

Lai YC, Aneja RK, Satchell MA, Clark RSB.

Methods Mol Biol. 2017;1608:27-43. doi: 10.1007/978-1-4939-6993-7_3.


Brain-Specific Serum Biomarkers Predict Neurological Morbidity in Diagnostically Diverse Pediatric Intensive Care Unit Patients.

Au AK, Bell MJ, Fink EL, Aneja RK, Kochanek PM, Clark RSB.

Neurocrit Care. 2018 Feb;28(1):26-34. doi: 10.1007/s12028-017-0414-7.


Centrosome amplification: a suspect in breast cancer and racial disparities.

Ogden A, Rida PCG, Aneja R.

Endocr Relat Cancer. 2017 Sep;24(9):T47-T64. doi: 10.1530/ERC-17-0072. Epub 2017 May 17. Review.


Application of Combination High-Throughput Phenotypic Screening and Target Identification Methods for the Discovery of Natural Product-Based Combination Drugs.

Isgut M, Rao M, Yang C, Subrahmanyam V, Rida PCG, Aneja R.

Med Res Rev. 2018 Mar;38(2):504-524. doi: 10.1002/med.21444. Epub 2017 May 16. Review.


American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock.

Davis AL, Carcillo JA, Aneja RK, Deymann AJ, Lin JC, Nguyen TC, Okhuysen-Cawley RS, Relvas MS, Rozenfeld RA, Skippen PW, Stojadinovic BJ, Williams EA, Yeh TS, Balamuth F, Brierley J, de Caen AR, Cheifetz IM, Choong K, Conway E Jr, Cornell T, Doctor A, Dugas MA, Feldman JD, Fitzgerald JC, Flori HR, Fortenberry JD, Graciano AL, Greenwald BM, Hall MW, Han YY, Hernan LJ, Irazuzta JE, Iselin E, van der Jagt EW, Jeffries HE, Kache S, Katyal C, Kissoon NT, Kon AA, Kutko MC, MacLaren G, Maul T, Mehta R, Odetola F, Parbuoni K, Paul R, Peters MJ, Ranjit S, Reuter-Rice KE, Schnitzler EJ, Scott HF, Torres A Jr, Weingarten-Abrams J, Weiss SL, Zimmerman JJ, Zuckerberg AL.

Crit Care Med. 2017 Jun;45(6):1061-1093. doi: 10.1097/CCM.0000000000002425.


Immunohistochemical Classification of Ampullary Carcinomas: Critical Reappraisal Fails to Confirm Prognostic Relevance for Recently Proposed Panels, and Highlights MUC5AC as a Strong Prognosticator.

Xue Y, Reid MD, Balci S, Quigley B, Muraki T, Memis B, Xia J, Hacihasanoglu E, Bedolla G, Pehlivanoglu B, Kim GE, Tajiri T, Ohike N, Aneja R, Krasinskas AM, Adsay V.

Am J Surg Pathol. 2017 Jul;41(7):865-876. doi: 10.1097/PAS.0000000000000863.


Three Hypothetical Inflammation Pathobiology Phenotypes and Pediatric Sepsis-Induced Multiple Organ Failure Outcome.

Carcillo JA, Halstead ES, Hall MW, Nguyen TC, Reeder R, Aneja R, Shakoory B, Simon D; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Investigators.

Pediatr Crit Care Med. 2017 Jun;18(6):513-523. doi: 10.1097/PCC.0000000000001122.


Tackling intra- and inter-tumor heterogeneity to combat triple negative breast cancer.

Wright N, Rida PCG, Aneja R.

Front Biosci (Landmark Ed). 2017 Jun 1;22:1549-1580. Review.


Absorption, Metabolic Stability, and Pharmacokinetics of Ginger Phytochemicals.

Mukkavilli R, Yang C, Singh Tanwar R, Ghareeb A, Luthra L, Aneja R.

Molecules. 2017 Mar 30;22(4). pii: E553. doi: 10.3390/molecules22040553.


Multinucleated polyploidy drives resistance to Docetaxel chemotherapy in prostate cancer.

Mittal K, Donthamsetty S, Kaur R, Yang C, Gupta MV, Reid MD, Choi DH, Rida PCG, Aneja R.

Br J Cancer. 2017 Apr 25;116(9):1186-1194. doi: 10.1038/bjc.2017.78. Epub 2017 Mar 23.


Prognostic value of CA20, a score based on centrosome amplification-associated genes, in breast tumors.

Ogden A, Rida PC, Aneja R.

Sci Rep. 2017 Mar 21;7(1):262. doi: 10.1038/s41598-017-00363-w.


Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells.

Mittal K, Choi DH, Ogden A, Donthamsetty S, Melton BD, Gupta MV, Pannu V, Cantuaria G, Varambally S, Reid MD, Jonsdottir K, Janssen EA, Aleskandarany MA, Ellis IO, Rakha EA, Rida PC, Aneja R.

Sci Rep. 2017 Mar 8;7:43984. doi: 10.1038/srep43984.


Dietary Supplementation With Nonfermentable Fiber Alters the Gut Microbiota and Confers Protection in Murine Models of Sepsis.

Morowitz MJ, Di Caro V, Pang D, Cummings J, Firek B, Rogers MB, Ranganathan S, Clark RSB, Aneja RK.

Crit Care Med. 2017 May;45(5):e516-e523. doi: 10.1097/CCM.0000000000002291.


Pathophysiology of Pediatric Multiple Organ Dysfunction Syndrome.

Carcillo JA, Podd B, Aneja R, Weiss SL, Hall MW, Cornell TT, Shanley TP, Doughty LA, Nguyen TC.

Pediatr Crit Care Med. 2017 Mar;18(3_suppl Suppl 1):S32-S45. doi: 10.1097/PCC.0000000000001052. Review.


Multi-institutional study of nuclear KIFC1 as a biomarker of poor prognosis in African American women with triple-negative breast cancer.

Ogden A, Garlapati C, Li XB, Turaga RC, Oprea-Ilies G, Wright N, Bhattarai S, Mittal K, Wetherilt CS, Krishnamurti U, Reid MD, Jones M, Gupta M, Osan R, Pattni S, Riaz A, Klimov S, Rao A, Cantuaria G, Rida PC, Aneja R.

Sci Rep. 2017 Feb 20;7:42289. doi: 10.1038/srep42289.


Preclinical Development of a Nontoxic Oral Formulation of Monoethanolamine, a Lipid Precursor, for Prostate Cancer Treatment.

Saxena R, Yang C, Rao M, Turaga RC, Garlapati C, Gundala SR, Myers K, Ghareeb A, Bhattarai S, Kamalinia G, Bristi S, Su D, Gadda G, Rida PCG, Cantuaria GH, Aneja R.

Clin Cancer Res. 2017 Jul 15;23(14):3781-3793. doi: 10.1158/1078-0432.CCR-16-1716. Epub 2017 Feb 6.


From Phantasmagoria to Reality?

Pang D, Aneja R.

Pediatr Crit Care Med. 2017 Feb;18(2):191-192. doi: 10.1097/PCC.0000000000001034. No abstract available.


Distinctions in Breast Tumor Recurrence Patterns Post-Therapy among Racially Distinct Populations.

Wright N, Xia J, Cantuaria G, Klimov S, Jones M, Neema P, Il'yasova D, Krishnamurti U, Li X, Reid MD, Gupta M, Rida PC, Osan R, Aneja R.

PLoS One. 2017 Jan 13;12(1):e0170095. doi: 10.1371/journal.pone.0170095. eCollection 2017.


Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury.

Au AK, Aneja RK, Bayır H, Bell MJ, Janesko-Feldman K, Kochanek PM, Clark RSB.

Neurocrit Care. 2017 Jun;26(3):348-355. doi: 10.1007/s12028-016-0351-x.


The more the messier: centrosome amplification as a novel biomarker for personalized treatment of colorectal cancers.

Mahathre MM, Rida PC, Aneja R.

J Biomed Res. 2016 Nov;30(6):441-451. doi: 10.7555/JBR.30.20150109. Epub 2015 Nov 10. Review.


Treatment and follow-up of venous thrombosis in the neonatal intensive care unit: a retrospective study.

Bohnhoff JC, DiSilvio SA, Aneja RK, Shenk JR, Domnina YA, Brozanski BS, Good M.

J Perinatol. 2017 Mar;37(3):306-310. doi: 10.1038/jp.2016.218. Epub 2016 Dec 1.


Targeted drugs and diagnostic assays: Companions in the race to combat ethnic disparity.

Wright N, Rida P, Krishnamurti U, Li X, Aneja R.

Front Biosci (Landmark Ed). 2017 Jan 1;22:193-211. Review.


Stromal PD-L1 Expression Is Associated With Better Disease-Free Survival in Triple-Negative Breast Cancer.

Li X, Wetherilt CS, Krishnamurti U, Yang J, Ma Y, Styblo TM, Meisel JL, Peng L, Siddiqui MT, Cohen C, Aneja R.

Am J Clin Pathol. 2016 Oct;146(4):496-502. doi: 10.1093/ajcp/aqw134.


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