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Items: 1 to 50 of 108

1.

Calorie restriction activates new adult born olfactory-bulb neurones in a ghrelin-dependent manner but acyl-ghrelin does not enhance sub-ventricular zone neurogenesis.

Ratcliff M, Rees D, McGrady S, Buntwal L, Hornsby AKE, Bayliss J, Kent BA, Bussey T, Saksida L, Beynon AL, Howell OW, Morgan AH, Sun Y, Andrews ZB, Wells T, Davies JS.

J Neuroendocrinol. 2019 Jun 10:e12755. doi: 10.1111/jne.12755. [Epub ahead of print]

PMID:
31179562
2.

Glucose availability regulates ghrelin-induced food intake in the ventral tegmental area.

Lockie SH, Stark R, Spanswick DC, Andrews ZB.

J Neuroendocrinol. 2019 Feb 11:e12696. doi: 10.1111/jne.12696. [Epub ahead of print]

PMID:
30742723
3.

Acylated Ghrelin Supports the Ovarian Transcriptome and Follicles in the Mouse: Implications for Fertility.

Sominsky L, Goularte JF, Andrews ZB, Spencer SJ.

Front Endocrinol (Lausanne). 2019 Jan 15;9:815. doi: 10.3389/fendo.2018.00815. eCollection 2018.

4.

Adolescent Inhalant Abuse Results in Adrenal Dysfunction and a Hypermetabolic Phenotype with Persistent Growth Impairments.

Crossin R, Andrews ZB, Sims NA, Pang T, Mathai M, Gooi JH, Stefanidis A, Oldfield BJ, Lawrence AJ, Duncan JR.

Neuroendocrinology. 2018;107(4):340-354. doi: 10.1159/000493686. Epub 2018 Sep 12.

PMID:
30208370
5.

Glucose Availability Predicts the Feeding Response to Ghrelin in Male Mice, an Effect Dependent on AMPK in AgRP Neurons.

Lockie SH, Stark R, Mequinion M, Ch'ng S, Kong D, Spanswick DC, Lawrence AJ, Andrews ZB.

Endocrinology. 2018 Nov 1;159(11):3605-3614. doi: 10.1210/en.2018-00536.

PMID:
30204871
6.

Growth changes after inhalant abuse and toluene exposure: A systematic review and meta-analysis of human and animal studies.

Crossin R, Lawrence AJ, Andrews ZB, Churilov L, Duncan JR.

Hum Exp Toxicol. 2019 Feb;38(2):157-172. doi: 10.1177/0960327118792064. Epub 2018 Jul 31.

PMID:
30062923
7.

Carnitine acetyltransferase (Crat) in hunger-sensing AgRP neurons permits adaptation to calorie restriction.

Reichenbach A, Stark R, Mequinion M, Lockie SH, Lemus MB, Mynatt RL, Luquet S, Andrews ZB.

FASEB J. 2018 Jun 22:fj201800634R. doi: 10.1096/fj.201800634R. [Epub ahead of print]

PMID:
29932868
8.

The role of corticostriatal-hypothalamic neural circuits in feeding behaviour: implications for obesity.

Clarke RE, Verdejo-Garcia A, Andrews ZB.

J Neurochem. 2018 Dec;147(6):715-729. doi: 10.1111/jnc.14455. Epub 2018 Jun 4. Review.

PMID:
29704424
9.

Carnitine Acetyltransferase in AgRP Neurons Is Required for the Homeostatic Adaptation to Restricted Feeding in Male Mice.

Reichenbach A, Mequinion M, Bayliss JA, Lockie SH, Lemus MB, Mynatt RL, Stark R, Andrews ZB.

Endocrinology. 2018 Jun 1;159(6):2473-2483. doi: 10.1210/en.2018-00131.

PMID:
29697769
10.

Targeting AMPK Signaling as a Neuroprotective Strategy in Parkinson's Disease.

Curry DW, Stutz B, Andrews ZB, Elsworth JD.

J Parkinsons Dis. 2018;8(2):161-181. doi: 10.3233/JPD-171296.

11.

AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning.

Reichenbach A, Stark R, Mequinion M, Denis RRG, Goularte JF, Clarke RE, Lockie SH, Lemus MB, Kowalski GM, Bruce CR, Huang C, Schittenhelm RB, Mynatt RL, Oldfield BJ, Watt MJ, Luquet S, Andrews ZB.

Cell Rep. 2018 Feb 13;22(7):1745-1759. doi: 10.1016/j.celrep.2018.01.067.

12.

AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis.

Galic S, Loh K, Murray-Segal L, Steinberg GR, Andrews ZB, Kemp BE.

Elife. 2018 Feb 13;7. pii: e32656. doi: 10.7554/eLife.32656.

13.

Ghrelin mediated neuroprotection - A possible therapy for Parkinson's disease?

Morgan AH, Rees DJ, Andrews ZB, Davies JS.

Neuropharmacology. 2018 Jul 1;136(Pt B):317-326. doi: 10.1016/j.neuropharm.2017.12.027. Epub 2017 Dec 23. Review.

PMID:
29277488
14.

Brain substrates of unhealthy versus healthy food choices: influence of homeostatic status and body mass index.

Harding IH, Andrews ZB, Mata F, Orlandea S, Martínez-Zalacaín I, Soriano-Mas C, Stice E, Verdejo-Garcia A.

Int J Obes (Lond). 2018 Mar;42(3):448-454. doi: 10.1038/ijo.2017.237. Epub 2017 Sep 25.

PMID:
29064475
15.

Metabolic diseases: Breakthrough discoveries in diabetes and obesity.

Andrews ZB.

J Neuroendocrinol. 2017 Oct;29(10). doi: 10.1111/jne.12536. No abstract available.

PMID:
28905499
16.

A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding.

Dodd GT, Andrews ZB, Simonds SE, Michael NJ, DeVeer M, Brüning JC, Spanswick D, Cowley MA, Tiganis T.

Cell Metab. 2017 Sep 5;26(3):577. doi: 10.1016/j.cmet.2017.08.001. No abstract available.

17.

Altered cross-talk between the hypothalamus and non-homeostatic regions linked to obesity and difficulty to lose weight.

Contreras-Rodríguez O, Vilar-López R, Andrews ZB, Navas JF, Soriano-Mas C, Verdejo-García A.

Sci Rep. 2017 Aug 30;7(1):9951. doi: 10.1038/s41598-017-09874-y.

18.

Less is more: Caloric regulation of neurogenesis and adult brain function.

Morgan AH, Andrews ZB, Davies JS.

J Neuroendocrinol. 2017 Oct;29(10). doi: 10.1111/jne.12512. Review.

PMID:
28771924
19.

A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding.

Dodd GT, Andrews ZB, Simonds SE, Michael NJ, DeVeer M, Brüning JC, Spanswick D, Cowley MA, Tiganis T.

Cell Metab. 2017 Aug 1;26(2):375-393.e7. doi: 10.1016/j.cmet.2017.07.013. Erratum in: Cell Metab. 2017 Sep 5;26(3):577.

20.

The role of ghrelin-responsive mediobasal hypothalamic neurons in mediating feeding responses to fasting.

Mani BK, Osborne-Lawrence S, Mequinion M, Lawrence S, Gautron L, Andrews ZB, Zigman JM.

Mol Metab. 2017 Jun 22;6(8):882-896. doi: 10.1016/j.molmet.2017.06.011. eCollection 2017 Aug.

21.

Acyl ghrelin improves cognition, synaptic plasticity deficits and neuroinflammation following amyloid β (Aβ1-40) administration in mice.

Santos VV, Stark R, Rial D, Silva HB, Bayliss JA, Lemus MB, Davies JS, Cunha RA, Prediger RD, Andrews ZB.

J Neuroendocrinol. 2017 May;29(5). doi: 10.1111/jne.12476.

PMID:
28380673
22.

The Ghrelin/GOAT System Regulates Obesity-Induced Inflammation in Male Mice.

Harvey RE, Howard VG, Lemus MB, Jois T, Andrews ZB, Sleeman MW.

Endocrinology. 2017 Jul 1;158(7):2179-2189. doi: 10.1210/en.2016-1832.

23.

Caloric Restriction Protects against Lactacystin-Induced Degeneration of Dopamine Neurons Independent of the Ghrelin Receptor.

Coppens J, Bentea E, Bayliss JA, Demuyser T, Walrave L, Albertini G, Van Liefferinge J, Deneyer L, Aourz N, Van Eeckhaut A, Portelli J, Andrews ZB, Massie A, De Bundel D, Smolders I.

Int J Mol Sci. 2017 Mar 4;18(3). pii: E558. doi: 10.3390/ijms18030558.

24.

Food Seeking in a Risky Environment: A Method for Evaluating Risk and Reward Value in Food Seeking and Consumption in Mice.

Lockie SH, McAuley CV, Rawlinson S, Guiney N, Andrews ZB.

Front Neurosci. 2017 Jan 30;11:24. doi: 10.3389/fnins.2017.00024. eCollection 2017.

25.

Is there a role for ghrelin in central dopaminergic systems? Focus on nigrostriatal and mesocorticolimbic pathways.

Stievenard A, Méquinion M, Andrews ZB, Destée A, Chartier-Harlin MC, Viltart O, Vanbesien-Mailliot CC.

Neurosci Biobehav Rev. 2017 Feb;73:255-275. doi: 10.1016/j.neubiorev.2016.11.021. Epub 2016 Nov 30. Review.

PMID:
27914942
26.

Transient Receptor Potential Canonical 3 (TRPC3) Channels Are Required for Hypothalamic Glucose Detection and Energy Homeostasis.

Chrétien C, Fenech C, Liénard F, Grall S, Chevalier C, Chaudy S, Brenachot X, Berges R, Louche K, Stark R, Nédélec E, Laderrière A, Andrews ZB, Benani A, Flockerzi V, Gascuel J, Hartmann J, Moro C, Birnbaumer L, Leloup C, Pénicaud L, Fioramonti X.

Diabetes. 2017 Feb;66(2):314-324. doi: 10.2337/db16-1114. Epub 2016 Nov 29.

27.

Early life disruption to the ghrelin system with over-eating is resolved in adulthood in male rats.

Sominsky L, Ziko I, Nguyen TX, Andrews ZB, Spencer SJ.

Neuropharmacology. 2017 Feb;113(Pt A):21-30. doi: 10.1016/j.neuropharm.2016.09.023. Epub 2016 Sep 23.

PMID:
27671325
28.

RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State.

Yi Lo JC, O'Connor AE, Andrews ZB, Lo C, Tiganis T, Watt MJ, O'Bryan MK.

Endocrinology. 2016 Dec;157(12):4732-4743. Epub 2016 Oct 12.

PMID:
27732084
29.

Ghrelin is the metabolic link connecting calorie restriction to neuroprotection.

Bayliss JA, Andrews ZB.

Neural Regen Res. 2016 Aug;11(8):1228-9. doi: 10.4103/1673-5374.189171. No abstract available.

30.

Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery.

Ratner C, Skov LJ, Raida Z, Bächler T, Bellmann-Sickert K, Le Foll C, Sivertsen B, Dalbøge LS, Hartmann B, Beck-Sickinger AG, Madsen AN, Jelsing J, Holst JJ, Lutz TA, Andrews ZB, Holst B.

Endocrinology. 2016 Sep;157(9):3482-92. doi: 10.1210/en.2016-1329. Epub 2016 Jul 20.

PMID:
27580810
31.

Des-Acyl Ghrelin and Ghrelin O-Acyltransferase Regulate Hypothalamic-Pituitary-Adrenal Axis Activation and Anxiety in Response to Acute Stress.

Stark R, Santos VV, Geenen B, Cabral A, Dinan T, Bayliss JA, Lockie SH, Reichenbach A, Lemus MB, Perello M, Spencer SJ, Kozicz T, Andrews ZB.

Endocrinology. 2016 Oct;157(10):3946-3957. Epub 2016 Aug 4.

PMID:
27490185
32.

Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons.

Bayliss JA, Lemus MB, Santos VV, Deo M, Davies JS, Kemp BE, Elsworth JD, Andrews ZB.

PLoS One. 2016 Jul 28;11(7):e0159381. doi: 10.1371/journal.pone.0159381. eCollection 2016.

33.

Protective actions of des-acylated ghrelin on brain injury and blood-brain barrier disruption after stroke in mice.

Ku JM, Taher M, Chin KY, Barsby T, Austin V, Wong CH, Andrews ZB, Spencer SJ, Miller AA.

Clin Sci (Lond). 2016 Sep 1;130(17):1545-58. doi: 10.1042/CS20160077. Epub 2016 Jun 14.

PMID:
27303049
34.

The Neurobiology of "Food Addiction" and Its Implications for Obesity Treatment and Policy.

Carter A, Hendrikse J, Lee N, Yücel M, Verdejo-Garcia A, Andrews ZB, Hall W.

Annu Rev Nutr. 2016 Jul 17;36:105-28. doi: 10.1146/annurev-nutr-071715-050909. Epub 2016 Jun 1. Review.

PMID:
27296500
35.

Correction to 'Obesity Impairs the Action of the Neuroendocrine Ghrelin System': [Trends in Endocrinology and Metabolism, 27 (2016) 54-63].

Zigman JM, Bouret SG, Andrews ZB.

Trends Endocrinol Metab. 2016 May;27(5):348. doi: 10.1016/j.tem.2016.02.007. Epub 2016 Mar 9. No abstract available.

PMID:
27106266
36.

Cinnamon users with prediabetes have a better fasting working memory: a cross-sectional function study.

Wahlqvist ML, Lee MS, Lee JT, Hsu CC, Chou YC, Fang WH, Liu HY, Xiu L, Andrews ZB.

Nutr Res. 2016 Apr;36(4):305-310. doi: 10.1016/j.nutres.2015.12.005. Epub 2015 Dec 8.

PMID:
27001275
37.

Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease.

Bayliss JA, Lemus MB, Stark R, Santos VV, Thompson A, Rees DJ, Galic S, Elsworth JD, Kemp BE, Davies JS, Andrews ZB.

J Neurosci. 2016 Mar 9;36(10):3049-63. doi: 10.1523/JNEUROSCI.4373-15.2016.

38.

Acylated but not des-acyl ghrelin is neuroprotective in an MPTP mouse model of Parkinson's disease.

Bayliss JA, Lemus M, Santos VV, Deo M, Elsworth JD, Andrews ZB.

J Neurochem. 2016 May;137(3):460-71. doi: 10.1111/jnc.13576. Epub 2016 Mar 11.

39.

Ghrelin-related peptides do not modulate vasodilator nitric oxide production or superoxide levels in mouse systemic arteries.

Ku JM, Sleeman MW, Sobey CG, Andrews ZB, Miller AA.

Clin Exp Pharmacol Physiol. 2016 Apr;43(4):468-75. doi: 10.1111/1440-1681.12548.

PMID:
26800483
40.

Obesity Impairs the Action of the Neuroendocrine Ghrelin System.

Zigman JM, Bouret SG, Andrews ZB.

Trends Endocrinol Metab. 2016 Jan;27(1):54-63. doi: 10.1016/j.tem.2015.09.010. Epub 2015 Nov 2. Review. Erratum in: Trends Endocrinol Metab. 2016 May;27(5):348.

41.

Short-term calorie restriction enhances adult hippocampal neurogenesis and remote fear memory in a Ghsr-dependent manner.

Hornsby AK, Redhead YT, Rees DJ, Ratcliff MS, Reichenbach A, Wells T, Francis L, Amstalden K, Andrews ZB, Davies JS.

Psychoneuroendocrinology. 2016 Jan;63:198-207. doi: 10.1016/j.psyneuen.2015.09.023. Epub 2015 Sep 25.

42.

Diet-induced obesity causes ghrelin resistance in reward processing tasks.

Lockie SH, Dinan T, Lawrence AJ, Spencer SJ, Andrews ZB.

Psychoneuroendocrinology. 2015 Dec;62:114-20. doi: 10.1016/j.psyneuen.2015.08.004. Epub 2015 Aug 11.

43.

Hypothalamic carnitine metabolism integrates nutrient and hormonal feedback to regulate energy homeostasis.

Stark R, Reichenbach A, Andrews ZB.

Mol Cell Endocrinol. 2015 Dec 15;418 Pt 1:9-16. doi: 10.1016/j.mce.2015.08.002. Epub 2015 Aug 8. Review.

PMID:
26261054
44.

Central Administration of the Ciliary Neurotrophic Factor Analogue, Axokine, Does Not Play a Role in Long-Term Energy Homeostasis in Adult Mice.

Borg ML, Reichenbach A, Lemus M, Oldfield BJ, Andrews ZB, Watt MJ.

Neuroendocrinology. 2016;103(3-4):223-9. doi: 10.1159/000435860. Epub 2015 Jun 18.

PMID:
26088805
45.

Ghrelin.

Müller TD, Nogueiras R, Andermann ML, Andrews ZB, Anker SD, Argente J, Batterham RL, Benoit SC, Bowers CY, Broglio F, Casanueva FF, D'Alessio D, Depoortere I, Geliebter A, Ghigo E, Cole PA, Cowley M, Cummings DE, Dagher A, Diano S, Dickson SL, Diéguez C, Granata R, Grill HJ, Grove K, Habegger KM, Heppner K, Heiman ML, Holsen L, Holst B, Inui A, Jansson JO, Kirchner H, Korbonits M, Laferrère B, LeRoux CW, Lopez M, Morin S, Nakazato M, Nass R, Perez-Tilve D, Pfluger PT, Schwartz TW, Seeley RJ, Sleeman M, Sun Y, Sussel L, Tong J, Thorner MO, van der Lely AJ, van der Ploeg LH, Zigman JM, Kojima M, Kangawa K, Smith RG, Horvath T, Tschöp MH.

Mol Metab. 2015 Mar 21;4(6):437-60. doi: 10.1016/j.molmet.2015.03.005. eCollection 2015 Jun. Review.

46.

A stereological analysis of NPY, POMC, Orexin, GFAP astrocyte, and Iba1 microglia cell number and volume in diet-induced obese male mice.

Lemus MB, Bayliss JA, Lockie SH, Santos VV, Reichenbach A, Stark R, Andrews ZB.

Endocrinology. 2015 May;156(5):1701-13. doi: 10.1210/en.2014-1961. Epub 2015 Mar 5.

PMID:
25742051
47.

Neonatal ghrelin programs development of hypothalamic feeding circuits.

Steculorum SM, Collden G, Coupe B, Croizier S, Lockie S, Andrews ZB, Jarosch F, Klussmann S, Bouret SG.

J Clin Invest. 2015 Feb;125(2):846-58. doi: 10.1172/JCI73688. Epub 2015 Jan 20.

48.

Leptin and insulin act on POMC neurons to promote the browning of white fat.

Dodd GT, Decherf S, Loh K, Simonds SE, Wiede F, Balland E, Merry TL, Münzberg H, Zhang ZY, Kahn BB, Neel BG, Bence KK, Andrews ZB, Cowley MA, Tiganis T.

Cell. 2015 Jan 15;160(1-2):88-104. doi: 10.1016/j.cell.2014.12.022.

49.

Acyl ghrelin acts in the brain to control liver function and peripheral glucose homeostasis in male mice.

Stark R, Reichenbach A, Lockie SH, Pracht C, Wu Q, Tups A, Andrews ZB.

Endocrinology. 2015 Mar;156(3):858-68. doi: 10.1210/en.2014-1733. Epub 2014 Dec 23.

PMID:
25535832
50.

Ghrelin's Role in the Hypothalamic-Pituitary-Adrenal Axis Stress Response: Implications for Mood Disorders.

Spencer SJ, Emmerzaal TL, Kozicz T, Andrews ZB.

Biol Psychiatry. 2015 Jul 1;78(1):19-27. doi: 10.1016/j.biopsych.2014.10.021. Epub 2014 Oct 31. Review.

PMID:
25534754

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