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A functional role for the cancer disparity-linked genes, CRYβB2 and CRYβB2P1, in the promotion of breast cancer.

Barrow MA, Martin ME, Coffey A, Andrews PL, Jones GS, Reaves DK, Parker JS, Troester MA, Fleming JM.

Breast Cancer Res. 2019 Sep 11;21(1):105. doi: 10.1186/s13058-019-1191-3.


Prospective severity classification of scientific procedures in cephalopods: Report of a COST FA1301 Working Group survey.

Cooke GM, Anderson DB, Begout ML, Dennison N, Osorio D, Tonkins B, Kristiansen T, Fiorito G, Galligioni V, Ponte G, Andrews PL.

Lab Anim. 2019 Dec;53(6):541-563. doi: 10.1177/0023677219864626. Epub 2019 Aug 31.


Advice on avoiding the Valley of Death: insights from a 3Rs model of aversive and emetic compound identification.

Williams RSB, Andrews PLR.

ALTEX. 2019;36(3):466-469. doi: 10.14573/altex.1810182. Epub 2019 Apr 2. No abstract available.


Functional brain networks and neuroanatomy underpinning nausea severity can predict nausea susceptibility using machine learning.

Ruffle JK, Patel A, Giampietro V, Howard MA, Sanger GJ, Andrews PLR, Williams SCR, Aziz Q, Farmer AD.

J Physiol. 2019 Mar;597(6):1517-1529. doi: 10.1113/JP277474. Epub 2019 Feb 27.


Editorial: The Digestive Tract of Cephalopods: At the Interface Between Physiology and Ecology.

Ponte G, Almansa E, Andrews PLR.

Front Physiol. 2018 Oct 9;9:1409. doi: 10.3389/fphys.2018.01409. eCollection 2018. No abstract available.


A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research.

Sanger GJ, Andrews PLR.

Front Pharmacol. 2018 Sep 4;9:913. doi: 10.3389/fphar.2018.00913. eCollection 2018. Review.


Cephalopod Brains: An Overview of Current Knowledge to Facilitate Comparison With Vertebrates.

Shigeno S, Andrews PLR, Ponte G, Fiorito G.

Front Physiol. 2018 Jul 20;9:952. doi: 10.3389/fphys.2018.00952. eCollection 2018. Review.


Last Word on Viewpoint: Looking beyond macrovenitlatory parameters and rethinking ventilator-induced lung injury.

Kollisch-Singule MC, Jain SV, Andrews PL, Satalin J, Gatto LA, Villar J, De Backer D, Gattinoni L, Nieman GF, Habashi NM.

J Appl Physiol (1985). 2018 May 1;124(5):1220-1221. doi: 10.1152/japplphysiol.00049.2018. No abstract available.


Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum.

Cocorocchio M, Baldwin AJ, Stewart B, Kim L, Harwood AJ, Thompson CRL, Andrews PLR, Williams RSB.

Dis Model Mech. 2018 Jan 29;11(1). pii: dmm032375. doi: 10.1242/dmm.032375.


The Gastric Ganglion of Octopus vulgaris: Preliminary Characterization of Gene- and Putative Neurochemical-Complexity, and the Effect of Aggregata octopiana Digestive Tract Infection on Gene Expression.

Baldascino E, Di Cristina G, Tedesco P, Hobbs C, Shaw TJ, Ponte G, Andrews PLR.

Front Physiol. 2017 Dec 15;8:1001. doi: 10.3389/fphys.2017.01001. eCollection 2017.


Gastric myoelectric activity during cisplatin-induced acute and delayed emesis reveals a temporal impairment of slow waves in ferrets: effects not reversed by the GLP-1 receptor antagonist, exendin (9-39).

Lu Z, Ngan MP, Lin G, Yew DTW, Fan X, Andrews PLR, Rudd JA.

Oncotarget. 2017 Oct 16;8(58):98691-98707. doi: 10.18632/oncotarget.21859. eCollection 2017 Nov 17.


Looking beyond macroventilatory parameters and rethinking ventilator-induced lung injury.

Kollisch-Singule MC, Jain SV, Andrews PL, Satalin J, Gatto LA, Villar J, De Backer D, Gattinoni L, Nieman GF, Habashi NM.

J Appl Physiol (1985). 2018 May 1;124(5):1214-1218. doi: 10.1152/japplphysiol.00412.2017. Epub 2017 Nov 16. No abstract available.


Prey Capture, Ingestion, and Digestion Dynamics of Octopus vulgaris Paralarvae Fed Live Zooplankton.

Nande M, Presa P, Roura Á, Andrews PLR, Pérez M.

Front Physiol. 2017 Aug 17;8:573. doi: 10.3389/fphys.2017.00573. eCollection 2017.


The Digestive Tract of Cephalopods: a Neglected Topic of Relevance to Animal Welfare in the Laboratory and Aquaculture.

Sykes AV, Almansa E, Cooke GM, Ponte G, Andrews PLR.

Front Physiol. 2017 Jul 17;8:492. doi: 10.3389/fphys.2017.00492. eCollection 2017. Review.


The Digestive Tract of Cephalopods: Toward Non-invasive In vivo Monitoring of Its Physiology.

Ponte G, Sykes AV, Cooke GM, Almansa E, Andrews PLR.

Front Physiol. 2017 Jun 19;8:403. doi: 10.3389/fphys.2017.00403. eCollection 2017.


Brain Activation by H1 Antihistamines Challenges Conventional View of Their Mechanism of Action in Motion Sickness: A Behavioral, c-Fos and Physiological Study in Suncus murinus (House Musk Shrew).

Tu L, Lu Z, Dieser K, Schmitt C, Chan SW, Ngan MP, Andrews PLR, Nalivaiko E, Rudd JA.

Front Physiol. 2017 Jun 14;8:412. doi: 10.3389/fphys.2017.00412. eCollection 2017.


Centrally located GLP-1 receptors modulate gastric slow waves and cardiovascular function in ferrets consistent with the induction of nausea.

Lu Z, Yeung CK, Lin G, Yew DTW, Andrews PLR, Rudd JA.

Neuropeptides. 2017 Oct;65:28-36. doi: 10.1016/j.npep.2017.04.006. Epub 2017 Apr 21.


Effect of Different Formulations of Magnesium Chloride Used As Anesthetic Agents on the Performance of the Isolated Heart of Octopus vulgaris.

Pugliese C, Mazza R, Andrews PL, Cerra MC, Fiorito G, Gattuso A.

Front Physiol. 2016 Dec 26;7:610. doi: 10.3389/fphys.2016.00610. eCollection 2016.


Autonomic changes induced by provocative motion in rats bred for high (HAB) and low (LAB) anxiety-related behavior: Paradoxical responses in LAB animals.

Carnevali L, Andrews PL, Neumann ID, Nalivaiko E, Sgoifo A.

Physiol Behav. 2016 Dec 1;167:363-373. doi: 10.1016/j.physbeh.2016.09.028. Epub 2016 Oct 1.


Insights into the central pathways involved in the emetic and behavioural responses to exendin-4 in the ferret.

Lu Z, Yeung CK, Lin G, Yew DT, Andrews PL, Rudd JA.

Auton Neurosci. 2017 Jan;202:122-135. doi: 10.1016/j.autneu.2016.09.003. Epub 2016 Sep 14.


Ondansetron and promethazine have differential effects on hypothermic responses to lithium chloride administration and to provocative motion in rats.

Guimaraes DD, Andrews PL, Rudd JA, Braga VA, Nalivaiko E.

Temperature (Austin). 2015 Oct 27;2(4):543-53. doi: 10.1080/23328940.2015.1071700. eCollection 2015 Oct-Dec.


The involvement of TRPV1 in emesis and anti-emesis.

Rudd JA, Nalivaiko E, Matsuki N, Wan C, Andrews PL.

Temperature (Austin). 2015 May 21;2(2):258-76. doi: 10.1080/23328940.2015.1043042. eCollection 2015 Apr-Jun. Review.


Mechanisms of wound closure following acute arm injury in Octopus vulgaris.

Shaw TJ, Osborne M, Ponte G, Fiorito G, Andrews PL.

Zoological Lett. 2016 Mar 29;2:8. doi: 10.1186/s40851-016-0044-5. eCollection 2016.


Bitter tastant responses in the amoeba Dictyostelium correlate with rat and human taste assays.

Cocorocchio M, Ives R, Clapham D, Andrews PL, Williams RS.

ALTEX. 2016;33(3):225-36. doi: 10.14573/altex.1509011. Epub 2015 Dec 22.


Guidelines for the Care and Welfare of Cephalopods in Research -A consensus based on an initiative by CephRes, FELASA and the Boyd Group.

Fiorito G, Affuso A, Basil J, Cole A, de Girolamo P, D'Angelo L, Dickel L, Gestal C, Grasso F, Kuba M, Mark F, Melillo D, Osorio D, Perkins K, Ponte G, Shashar N, Smith D, Smith J, Andrews PL.

Lab Anim. 2015 Jul;49(2 Suppl):1-90. doi: 10.1177/0023677215580006.


Alveolar instability (atelectrauma) is not identified by arterial oxygenation predisposing the development of an occult ventilator-induced lung injury.

Andrews PL, Sadowitz B, Kollisch-Singule M, Satalin J, Roy S, Snyder K, Gatto LA, Nieman GF, Habashi NM.

Intensive Care Med Exp. 2015 Dec;3(1):54. doi: 10.1186/s40635-015-0054-1. Epub 2015 Jun 9.


Visually induced nausea causes characteristic changes in cerebral, autonomic and endocrine function in humans.

Farmer AD, Ban VF, Coen SJ, Sanger GJ, Barker GJ, Gresty MA, Giampietro VP, Williams SC, Webb DL, Hellström PM, Andrews PL, Aziz Q.

J Physiol. 2015 Mar 1;593(5):1183-96. doi: 10.1113/jphysiol.2014.284240. Epub 2015 Jan 29.


Differential hypoglycaemic, anorectic, autonomic and emetic effects of the glucagon-like peptide receptor agonist, exendin-4, in the conscious telemetered ferret.

Lu Z, Percie Du Sert N, Chan SW, Yeung CK, Lin G, Yew DT, Andrews PL, Rudd JA.

J Transl Med. 2014 Dec 10;12:327. doi: 10.1186/s12967-014-0327-6.


Netupitant and palonosetron (NEPA): a winning team in the race for the optimal treatment of chemotherapy-induced nausea and vomiting?

Andrews PL.

Ann Oncol. 2014 Jul;25(7):1258-9. doi: 10.1093/annonc/mdu190. Epub 2014 Jun 18. No abstract available.


The role of the parasympathetic nervous system in visually induced motion sickness: systematic review and meta-analysis.

Farmer AD, Al Omran Y, Aziz Q, Andrews PL.

Exp Brain Res. 2014 Aug;232(8):2665-73. doi: 10.1007/s00221-014-3964-3. Epub 2014 May 4. Review.


Nausea and the quest for the perfect anti-emetic.

Andrews PL, Sanger GJ.

Eur J Pharmacol. 2014 Jan 5;722:108-21. doi: 10.1016/j.ejphar.2013.09.072. Epub 2013 Oct 22.


Early application of airway pressure release ventilation may reduce mortality in high-risk trauma patients: a systematic review of observational trauma ARDS literature.

Andrews PL, Shiber JR, Jaruga-Killeen E, Roy S, Sadowitz B, O'Toole RV, Gatto LA, Nieman GF, Scalea T, Habashi NM.

J Trauma Acute Care Surg. 2013 Oct;75(4):635-41. doi: 10.1097/TA.0b013e31829d3504. Review.


A novel human receptor involved in bitter tastant detection identified using Dictyostelium discoideum.

Robery S, Tyson R, Dinh C, Kuspa A, Noegel AA, Bretschneider T, Andrews PL, Williams RS.

J Cell Sci. 2013 Dec 1;126(Pt 23):5465-76. doi: 10.1242/jcs.136440. Epub 2013 Sep 4.


The relationship between gastric motility and nausea: gastric prokinetic agents as treatments.

Sanger GJ, Broad J, Andrews PL.

Eur J Pharmacol. 2013 Sep 5;715(1-3):10-4. doi: 10.1016/j.ejphar.2013.06.031. Epub 2013 Jul 4. Review.


What's in a name? Mechanical ventilation is at the mercy of the operator.

Andrews PL, Scalea T, Habashi NM.

J Trauma Acute Care Surg. 2013 May;74(5):1377-8. doi: 10.1097/TA.0b013e31828b7da5. No abstract available.


Why can't rodents vomit? A comparative behavioral, anatomical, and physiological study.

Horn CC, Kimball BA, Wang H, Kaus J, Dienel S, Nagy A, Gathright GR, Yates BJ, Andrews PL.

PLoS One. 2013 Apr 10;8(4):e60537. doi: 10.1371/journal.pone.0060537. Print 2013. Erratum in: PLoS One. 2013;8(6). 10.1371/annotation/1c75cd5d-9dde-4ace-8524-a4980745e804.


Investigating the effect of emetic compounds on chemotaxis in Dictyostelium identifies a non-sentient model for bitter and hot tastant research.

Robery S, Mukanowa J, Percie du Sert N, Andrews PL, Williams RS.

PLoS One. 2011;6(9):e24439. doi: 10.1371/journal.pone.0024439. Epub 2011 Sep 8.


Predicting the emetic liability of novel chemical entities: a comparative study.

du Sert NP, Holmes AM, Wallis R, Andrews PL.

Br J Pharmacol. 2012 Mar;165(6):1848-1867. doi: 10.1111/j.1476-5381.2011.01669.x. Review.


Introduction: laboratory invertebrates: only spineless, or spineless and painless?

Andrews PL.

ILAR J. 2011;52(2):121-5. No abstract available.


The translational value of rodent gastrointestinal functions: a cautionary tale.

Sanger GJ, Holbrook JD, Andrews PL.

Trends Pharmacol Sci. 2011 Jul;32(7):402-9. doi: 10.1016/ Epub 2011 Apr 29. Review.


Cannabinoid-induced reduction in antral pacemaker frequency: a telemetric study in the ferret.

Percie du Sert N, Ho WS, Rudd JA, Andrews PL.

Neurogastroenterol Motil. 2010 Nov;22(11):1257-66, e324. doi: 10.1111/j.1365-2982.2010.01581.x. Epub 2010 Aug 22.


Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT₃ receptor antagonists.

Percie du Sert N, Rudd JA, Apfel CC, Andrews PL.

Cancer Chemother Pharmacol. 2011 Mar;67(3):667-86. doi: 10.1007/s00280-010-1339-4. Epub 2010 May 28. Review.


Telemetry in a motion-sickness model implicates the abdominal vagus in motion-induced gastric dysrhythmia.

Percie du Sert N, Chu KM, Wai MK, Rudd JA, Andrews PL.

Exp Physiol. 2010 Jul;95(7):768-73. doi: 10.1113/expphysiol.2009.052001. Epub 2010 Apr 1.


Reduced normogastric electrical activity associated with emesis: a telemetric study in ferrets.

Percie du Sert N, Chu KM, Wai MK, Rudd JA, Andrews PL.

World J Gastroenterol. 2009 Dec 28;15(48):6034-43.


Olvanil, a non-pungent vanilloid enhances the gastrointestinal toxicity of cisplatin in the ferret.

Chu KM, Ngan MP, Wai MK, Yeung CK, Andrews PL, Percie du Sert N, Lin G, Rudd JA.

Toxicol Lett. 2010 Feb 15;192(3):402-7. doi: 10.1016/j.toxlet.2009.11.015. Epub 2009 Nov 30.


Olvanil: a non-pungent TRPV1 activator has anti-emetic properties in the ferret.

Chu KM, Ngan MP, Wai MK, Yeung CK, Andrews PL, Percie du Sert N, Rudd JA.

Neuropharmacology. 2010 Feb;58(2):383-91. doi: 10.1016/j.neuropharm.2009.10.002. Epub 2009 Oct 13.


The delayed phase of cisplatin-induced emesis is mediated by the area postrema and not the abdominal visceral innervation in the ferret.

Percie du Sert N, Rudd JA, Moss R, Andrews PL.

Neurosci Lett. 2009 Nov 6;465(1):16-20. doi: 10.1016/j.neulet.2009.08.075. Epub 2009 Sep 3.


Opportunities for the replacement of animals in the study of nausea and vomiting.

Holmes AM, Rudd JA, Tattersall FD, Aziz Q, Andrews PL.

Br J Pharmacol. 2009 Jul;157(6):865-80. doi: 10.1111/j.1476-5381.2009.00176.x. Epub 2009 Apr 9. Review.


Determination of metal ion content of beverages and estimation of target hazard quotients: a comparative study.

Hague T, Petroczi A, Andrews PL, Barker J, Naughton DP.

Chem Cent J. 2008 Jun 25;2:13. doi: 10.1186/1752-153X-2-13.


Adaptive upregulation of gastric and hypothalamic ghrelin receptors and increased plasma ghrelin in a model of cancer chemotherapy-induced dyspepsia.

Malik NM, Moore GB, Kaur R, Liu YL, Wood SL, Morrow RW, Sanger GJ, Andrews PL.

Regul Pept. 2008 Jun 5;148(1-3):33-8. doi: 10.1016/j.regpep.2008.03.005. Epub 2008 Mar 25.


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