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Items: 43


Two factor authentication: Asf1 mediates crosstalk between H3 K14 and K56 acetylation.

Cote JM, Kuo YM, Henry RA, Scherman H, Krzizike DD, Andrews AJ.

Nucleic Acids Res. 2019 Jun 13. pii: gkz508. doi: 10.1093/nar/gkz508. [Epub ahead of print]


One minute analysis of 200 histone posttranslational modifications by direct injection mass spectrometry.

Sidoli S, Kori Y, Lopes M, Yuan ZF, Kim HJ, Kulej K, Janssen KA, Agosto LM, Cunha JPCD, Andrews AJ, Garcia BA.

Genome Res. 2019 Jun;29(6):978-987. doi: 10.1101/gr.247353.118. Epub 2019 May 23.


Boreal marine fauna from the Barents Sea disperse to Arctic Northeast Greenland.

Andrews AJ, Christiansen JS, Bhat S, Lynghammar A, Westgaard JI, Pampoulie C, Præbel K.

Sci Rep. 2019 Apr 9;9(1):5799. doi: 10.1038/s41598-019-42097-x.


T cell activation triggers reversible inosine-5'-monophosphate dehydrogenase assembly.

Duong-Ly KC, Kuo YM, Johnson MC, Cote JM, Kollman JM, Soboloff J, Rall GF, Andrews AJ, Peterson JR.

J Cell Sci. 2018 Sep 5;131(17). pii: jcs223289. doi: 10.1242/jcs.223289.


S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice.

Lee HO, Wang L, Kuo YM, Andrews AJ, Gupta S, Kruger WD.

Mol Genet Metab Rep. 2018 Jan 12;15:15-21. doi: 10.1016/j.ymgmr.2018.01.002. eCollection 2018 Jun.


Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma.

Gordon RE, Zhang L, Peri S, Kuo YM, Du F, Egleston BL, Ng JMY, Andrews AJ, Astsaturov I, Curran T, Yang ZJ.

Clin Cancer Res. 2018 Mar 15;24(6):1375-1388. doi: 10.1158/1078-0432.CCR-17-2923. Epub 2018 Feb 6.


IL-35 (Interleukin-35) Suppresses Endothelial Cell Activation by Inhibiting Mitochondrial Reactive Oxygen Species-Mediated Site-Specific Acetylation of H3K14 (Histone 3 Lysine 14).

Li X, Shao Y, Sha X, Fang P, Kuo YM, Andrews AJ, Li Y, Yang WY, Maddaloni M, Pascual DW, Luo JJ, Jiang X, Wang H, Yang X.

Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):599-609. doi: 10.1161/ATVBAHA.117.310626. Epub 2018 Jan 25.


HDAC8 substrate selectivity is determined by long- and short-range interactions leading to enhanced reactivity for full-length histone substrates compared with peptides.

Castañeda CA, Wolfson NA, Leng KR, Kuo YM, Andrews AJ, Fierke CA.

J Biol Chem. 2017 Dec 29;292(52):21568-21577. doi: 10.1074/jbc.M117.811026. Epub 2017 Nov 6.


An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis.

Stepanova DS, Semenova G, Kuo YM, Andrews AJ, Ammoun S, Hanemann CO, Chernoff J.

Cancer Res. 2017 Sep 15;77(18):5026-5038. doi: 10.1158/0008-5472.CAN-16-2834. Epub 2017 Jul 20.


Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe.

Yadav RK, Jablonowski CM, Fernandez AG, Lowe BR, Henry RA, Finkelstein D, Barnum KJ, Pidoux AL, Kuo YM, Huang J, O'Connell MJ, Andrews AJ, Onar-Thomas A, Allshire RC, Partridge JF.

Elife. 2017 Jul 18;6. pii: e27406. doi: 10.7554/eLife.27406.


Identification of the Serine Biosynthesis Pathway as a Critical Component of BRAF Inhibitor Resistance of Melanoma, Pancreatic, and Non-Small Cell Lung Cancer Cells.

Ross KC, Andrews AJ, Marion CD, Yen TJ, Bhattacharjee V.

Mol Cancer Ther. 2017 Aug;16(8):1596-1609. doi: 10.1158/1535-7163.MCT-16-0798. Epub 2017 May 12.


Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.

Schuetze KB, Stratton MS, Blakeslee WW, Wempe MF, Wagner FF, Holson EB, Kuo YM, Andrews AJ, Gilbert TM, Hooker JM, McKinsey TA.

J Pharmacol Exp Ther. 2017 Apr;361(1):140-150. doi: 10.1124/jpet.116.237701. Epub 2017 Feb 7.


Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels.

Carrer A, Parris JL, Trefely S, Henry RA, Montgomery DC, Torres A, Viola JM, Kuo YM, Blair IA, Meier JL, Andrews AJ, Snyder NW, Wellen KE.

J Biol Chem. 2017 Feb 24;292(8):3312-3322. doi: 10.1074/jbc.M116.750620. Epub 2017 Jan 11.


Interaction with the DNA Repair Protein Thymine DNA Glycosylase Regulates Histone Acetylation by p300.

Henry RA, Mancuso P, Kuo YM, Tricarico R, Tini M, Cole PA, Bellacosa A, Andrews AJ.

Biochemistry. 2016 Dec 13;55(49):6766-6775. Epub 2016 Dec 1.


ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.

Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, Metallo CM, Snyder NW, Andrews AJ, Wellen KE.

Cell Rep. 2016 Oct 18;17(4):1037-1052. doi: 10.1016/j.celrep.2016.09.069.


Lack of global epigenetic methylation defects in CBS deficient mice.

Lee HO, Wang L, Kuo YM, Gupta S, Slifker MJ, Li YS, Andrews AJ, Kruger WD.

J Inherit Metab Dis. 2017 Jan;40(1):113-120. doi: 10.1007/s10545-016-9958-5. Epub 2016 Jul 21.


Modulation of p300/CBP Acetylation of Nucleosomes by Bromodomain Ligand I-CBP112.

Zucconi BE, Luef B, Xu W, Henry RA, Nodelman IM, Bowman GD, Andrews AJ, Cole PA.

Biochemistry. 2016 Jul 12;55(27):3727-34. doi: 10.1021/acs.biochem.6b00480. Epub 2016 Jul 1.


Global Profiling of Acetyltransferase Feedback Regulation.

Montgomery DC, Garlick JM, Kulkarni RA, Kennedy S, Allali-Hassani A, Kuo YM, Andrews AJ, Wu H, Vedadi M, Meier JL.

J Am Chem Soc. 2016 May 25;138(20):6388-91. doi: 10.1021/jacs.6b03036. Epub 2016 May 17.


Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell Activation.

Li X, Fang P, Li Y, Kuo YM, Andrews AJ, Nanayakkara G, Johnson C, Fu H, Shan H, Du F, Hoffman NE, Yu D, Eguchi S, Madesh M, Koch WJ, Sun J, Jiang X, Wang H, Yang X.

Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1090-100. doi: 10.1161/ATVBAHA.115.306964. Epub 2016 Apr 28.


Quantitative Measurement of Histone Tail Acetylation Reveals Stage-Specific Regulation and Response to Environmental Changes during Drosophila Development.

Henry RA, Singh T, Kuo YM, Biester A, O'Keefe A, Lee S, Andrews AJ, O'Reilly AM.

Biochemistry. 2016 Mar 22;55(11):1663-72. doi: 10.1021/acs.biochem.5b01070. Epub 2016 Feb 18.


Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer.

Raynal NJ, Lee JT, Wang Y, Beaudry A, Madireddi P, Garriga J, Malouf GG, Dumont S, Dettman EJ, Gharibyan V, Ahmed S, Chung W, Childers WE, Abou-Gharbia M, Henry RA, Andrews AJ, Jelinek J, Cui Y, Baylin SB, Gill DL, Issa JP.

Cancer Res. 2016 Mar 15;76(6):1494-505. doi: 10.1158/0008-5472.CAN-14-2391. Epub 2015 Dec 30.


Site specificity analysis of Piccolo NuA4-mediated acetylation for different histone complexes.

Kuo YM, Henry RA, Tan S, Côté J, Andrews AJ.

Biochem J. 2015 Dec 1;472(2):239-48. doi: 10.1042/BJ20150654. Epub 2015 Sep 29.


Measuring specificity in multi-substrate/product systems as a tool to investigate selectivity in vivo.

Kuo YM, Henry RA, Andrews AJ.

Biochim Biophys Acta. 2016 Jan;1864(1):70-6. doi: 10.1016/j.bbapap.2015.08.011. Epub 2015 Aug 29. Review.


Utilizing targeted mass spectrometry to demonstrate Asf1-dependent increases in residue specificity for Rtt109-Vps75 mediated histone acetylation.

Kuo YM, Henry RA, Huang L, Chen X, Stargell LA, Andrews AJ.

PLoS One. 2015 Mar 17;10(3):e0118516. doi: 10.1371/journal.pone.0118516. eCollection 2015.


Changing the selectivity of p300 by acetyl-CoA modulation of histone acetylation.

Henry RA, Kuo YM, Bhattacharjee V, Yen TJ, Andrews AJ.

ACS Chem Biol. 2015 Jan 16;10(1):146-56. doi: 10.1021/cb500726b. Epub 2014 Nov 6.


A quantitative multiplexed mass spectrometry assay for studying the kinetic of residue-specific histone acetylation.

Kuo YM, Henry RA, Andrews AJ.

Methods. 2014 Dec;70(2-3):127-33. doi: 10.1016/j.ymeth.2014.08.003. Epub 2014 Aug 11.


Differences in specificity and selectivity between CBP and p300 acetylation of histone H3 and H3/H4.

Henry RA, Kuo YM, Andrews AJ.

Biochemistry. 2013 Aug 27;52(34):5746-59. doi: 10.1021/bi400684q. Epub 2013 Aug 12.


Quantitating the specificity and selectivity of Gcn5-mediated acetylation of histone H3.

Kuo YM, Andrews AJ.

PLoS One. 2013;8(2):e54896. doi: 10.1371/journal.pone.0054896. Epub 2013 Feb 21. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/b2bf9c2e-90a9-4228-9b38-2f1bc977a437.


Classification of activity engagement in individuals with severe physical disabilities using signals of the peripheral nervous system.

Kushki A, Andrews AJ, Power SD, King G, Chau T.

PLoS One. 2012;7(2):e30373. doi: 10.1371/journal.pone.0030373. Epub 2012 Feb 17.


Nucleosome structure(s) and stability: variations on a theme.

Andrews AJ, Luger K.

Annu Rev Biophys. 2011;40:99-117. doi: 10.1146/annurev-biophys-042910-155329. Review.


A coupled equilibrium approach to study nucleosome thermodynamics.

Andrews AJ, Luger K.

Methods Enzymol. 2011;488:265-85. doi: 10.1016/B978-0-12-381268-1.00011-2.


Nucleosome accessibility governed by the dimer/tetramer interface.

Böhm V, Hieb AR, Andrews AJ, Gansen A, Rocker A, Tóth K, Luger K, Langowski J.

Nucleic Acids Res. 2011 Apr;39(8):3093-102. doi: 10.1093/nar/gkq1279. Epub 2010 Dec 21.


The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions.

Andrews AJ, Chen X, Zevin A, Stargell LA, Luger K.

Mol Cell. 2010 Mar 26;37(6):834-42. doi: 10.1016/j.molcel.2010.01.037.


NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P.

Koutmou KS, Casiano-Negroni A, Getz MM, Pazicni S, Andrews AJ, Penner-Hahn JE, Al-Hashimi HM, Fierke CA.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2479-84. doi: 10.1073/pnas.0906319107. Epub 2010 Jan 25.


Histone chaperone specificity in Rtt109 activation.

Park YJ, Sudhoff KB, Andrews AJ, Stargell LA, Luger K.

Nat Struct Mol Biol. 2008 Sep;15(9):957-64.


Analysis of flavivirus NS5 methyltransferase cap binding.

Geiss BJ, Thompson AA, Andrews AJ, Sons RL, Gari HH, Keenan SM, Peersen OB.

J Mol Biol. 2009 Feb 6;385(5):1643-54. doi: 10.1016/j.jmb.2008.11.058. Epub 2008 Dec 11.


A thermodynamic model for Nap1-histone interactions.

Andrews AJ, Downing G, Brown K, Park YJ, Luger K.

J Biol Chem. 2008 Nov 21;283(47):32412-8. doi: 10.1074/jbc.M805918200. Epub 2008 Aug 25.


Roles of protein subunits in RNA-protein complexes: lessons from ribonuclease P.

Hsieh J, Andrews AJ, Fierke CA.

Biopolymers. 2004 Jan;73(1):79-89. Review.


Compact 2.5-W 10-kHz Nd:YLF-pumped dye laser.

McGonigle AJ, Andrews AJ, Coutts DW, Hogan GP, Johnston KS, Moorhouse JD, Webb CE.

Appl Opt. 2002 Mar 20;41(9):1714-7.


Inadvertent hypothermia. A comparison of postoperative cholecystectomy patients by age.

Andrews AJ.

AORN J. 1990 Nov;52(5):987-91. No abstract available.


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