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Items: 48

1.

Obesity Causes Renal Mitochondrial Dysfunction and Energy Imbalance and Accelerates Chronic Kidney Disease in Mice.

Andres-Hernando A, Lanaspa MA, Kuwabara M, Orlicky DJ, Cicerchi C, Bales E, Garcia GE, Roncal-Jimenez CA, Sato Y, Johnson RJ.

Am J Physiol Renal Physiol. 2019 Aug 14. doi: 10.1152/ajprenal.00203.2019. [Epub ahead of print]

PMID:
31411075
2.

The increase of core temperature affected the progression of kidney injury by repeated heat stress exposure.

Sato Y, Roncal-Jimenez CA, Andres-Hernando A, Jensen T, Tolan DR, Sanchez-Lozada LG, Newman LS, Butler-Dawson J, Sorensen C, Glaser J, Miyazaki M, Diaz HF, Ishimoto T, Kosugi T, Maruyama S, Garcia GE, Lanaspa MA, Johnson RJ.

Am J Physiol Renal Physiol. 2019 Aug 7. doi: 10.1152/ajprenal.00259.2019. [Epub ahead of print]

PMID:
31390229
3.

Endogenous fructose production: what do we know and how relevant is it?

Andres-Hernando A, Johnson RJ, Lanaspa MA.

Curr Opin Clin Nutr Metab Care. 2019 Jul;22(4):289-294. doi: 10.1097/MCO.0000000000000573.

PMID:
31166222
4.

Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats.

Sanchez-Lozada LG, Andres-Hernando A, Garcia-Arroyo FE, Cicerchi C, Li N, Kuwabara M, Roncal-Jimenez CA, Johnson RJ, Lanaspa MA.

J Biol Chem. 2019 Mar 15;294(11):4272-4281. doi: 10.1074/jbc.RA118.006158. Epub 2019 Jan 16.

PMID:
30651350
5.

Fasting blood glucose is predictive of hypertension in a general Japanese population.

Kuwabara M, Chintaluru Y, Kanbay M, Niwa K, Hisatome I, Andres-Hernando A, Roncal-Jimenez C, Ohno M, Johnson RJ, Lanaspa MA.

J Hypertens. 2019 Jan;37(1):167-174. doi: 10.1097/HJH.0000000000001895.

PMID:
30507865
6.

Increased Serum Uric Acid over five years is a Risk Factor for Developing Fatty Liver.

Jensen T, Niwa K, Hisatome I, Kanbay M, Andres-Hernando A, Roncal-Jimenez CA, Sato Y, Garcia G, Ohno M, Lanaspa MA, Johnson RJ, Kuwabara M.

Sci Rep. 2018 Aug 6;8(1):11735. doi: 10.1038/s41598-018-30267-2.

7.

Rehydration with fructose worsens dehydration-induced renal damage.

Milagres T, García-Arroyo FE, Lanaspa MA, Garcia G, Ishimoto T, Andres-Hernando A, Kuwabara M, Jensen T, Sato Y, Glaser J, Sánchez-Lozada LG, Johnson RJ, Roncal-Jimenez C.

BMC Nephrol. 2018 Jul 13;19(1):180. doi: 10.1186/s12882-018-0963-9.

8.

Correction: Increased Serum Sodium and Serum Osmolarity Are Independent Risk Factors for Developing Chronic Kidney Disease; 5 Year Cohort Study.

Kuwabara M, Hisatome I, Roncal-Jimenez CA, Niwa K, Andres-Hernando A, Jensen T, Bjornstad P, Milagres T, Cicerchi C, Song Z, Garcia G, Sánchez-Lozada LG, Ohno M, Lanaspa MA, Johnson RJ.

PLoS One. 2018 May 17;13(5):e0197941. doi: 10.1371/journal.pone.0197941. eCollection 2018.

9.

Upregulation of CD80 on glomerular podocytes plays an important role in development of proteinuria following pig-to-baboon xeno-renal transplantation - an experimental study.

Rivard CJ, Tanabe T, Lanaspa MA, Watanabe H, Nomura S, Andres-Hernando A, Garth K, Sekijima M, Ishimoto T, Ariyoshi Y, Garcia GE, Shah J, Lennan B, Tasaki M, Pomposelli T, Shimizu A, Sachs DH, Johnson RJ, Yamada K.

Transpl Int. 2018 Oct;31(10):1164-1177. doi: 10.1111/tri.13273. Epub 2018 Jun 5.

10.

Different effects of global osteopontin and macrophage osteopontin in glomerular injury.

Trostel J, Truong LD, Roncal-Jimenez C, Miyazaki M, Miyazaki-Anzai S, Kuwabara M, McMahan R, Andres-Hernando A, Sato Y, Jensen T, Lanaspa MA, Johnson RJ, Garcia GE.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F759-F768. doi: 10.1152/ajprenal.00458.2017. Epub 2018 May 2.

PMID:
29717936
11.

Experimental heat stress nephropathy and liver injury are improved by allopurinol.

Roncal-Jimenez CA, Sato Y, Milagres T, Andres Hernando A, García G, Bjornstad P, Dawson JB, Sorensen C, Newman L, Krisher L, Madero M, Glaser J, Gárcía-Trabanino R, Romero EJ, Song Z, Jensen T, Kuwabara M, Rodriguez-Iturbe B, Sanchez-Lozada LG, Lanaspa MA, Johnson RJ.

Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F726-F733. doi: 10.1152/ajprenal.00543.2017. Epub 2018 Apr 18.

PMID:
29667911
12.

Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice.

Lanaspa MA, Andres-Hernando A, Orlicky DJ, Cicerchi C, Jang C, Li N, Milagres T, Kuwabara M, Wempe MF, Rabinowitz JD, Johnson RJ, Tolan DR.

J Clin Invest. 2018 Jun 1;128(6):2226-2238. doi: 10.1172/JCI94427. Epub 2018 Apr 23.

13.

High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism.

Lanaspa MA, Kuwabara M, Andres-Hernando A, Li N, Cicerchi C, Jensen T, Orlicky DJ, Roncal-Jimenez CA, Ishimoto T, Nakagawa T, Rodriguez-Iturbe B, MacLean PS, Johnson RJ.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3138-3143. doi: 10.1073/pnas.1713837115. Epub 2018 Mar 5. Erratum in: Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9509.

14.

Uric Acid Is a Strong Risk Marker for Developing Hypertension From Prehypertension: A 5-Year Japanese Cohort Study.

Kuwabara M, Hisatome I, Niwa K, Hara S, Roncal-Jimenez CA, Bjornstad P, Nakagawa T, Andres-Hernando A, Sato Y, Jensen T, Garcia G, Rodriguez-Iturbe B, Ohno M, Lanaspa MA, Johnson RJ.

Hypertension. 2018 Jan;71(1):78-86. doi: 10.1161/HYPERTENSIONAHA.117.10370. Epub 2017 Dec 4.

15.

"Metabolically Healthy" Obesity and Hyperuricemia Increase Risk for Hypertension and Diabetes: 5-year Japanese Cohort Study.

Kuwabara M, Kuwabara R, Hisatome I, Niwa K, Roncal-Jimenez CA, Bjornstad P, Andres-Hernando A, Sato Y, Jensen T, Garcia G, Ohno M, Hill JO, Lanaspa MA, Johnson RJ.

Obesity (Silver Spring). 2017 Nov;25(11):1997-2008. doi: 10.1002/oby.22000. Epub 2017 Sep 18.

16.

Asymptomatic Hyperuricemia Without Comorbidities Predicts Cardiometabolic Diseases: Five-Year Japanese Cohort Study.

Kuwabara M, Niwa K, Hisatome I, Nakagawa T, Roncal-Jimenez CA, Andres-Hernando A, Bjornstad P, Jensen T, Sato Y, Milagres T, Garcia G, Ohno M, Lanaspa MA, Johnson RJ.

Hypertension. 2017 Jun;69(6):1036-1044. doi: 10.1161/HYPERTENSIONAHA.116.08998. Epub 2017 Apr 10.

17.

Erratum to: Dietary and commercialized fructose: Sweet or sour?

Yerlikaya A, Dagel T, King C, Kuwabara M, Lanaspa MA, Andres-Hernando A, Covic A, Manitius J, Sag AA, Kanbay M.

Int Urol Nephrol. 2017 Sep;49(9):1699. doi: 10.1007/s11255-017-1579-x. No abstract available.

PMID:
28382575
18.

Early peritoneal dialysis reduces lung inflammation in mice with ischemic acute kidney injury.

Altmann C, Ahuja N, Kiekhaefer CM, Andres Hernando A, Okamura K, Bhargava R, Duplantis J, Kirkbride-Romeo LA, Huckles J, Fox BM, Kahn K, Soranno D, Gil HW, Teitelbaum I, Faubel S.

Kidney Int. 2017 Aug;92(2):365-376. doi: 10.1016/j.kint.2017.01.020. Epub 2017 Mar 16.

19.

Elevated Serum Uric Acid Level Predicts Rapid Decline in Kidney Function.

Kuwabara M, Bjornstad P, Hisatome I, Niwa K, Roncal-Jimenez CA, Andres-Hernando A, Jensen T, Milagres T, Sato Y, Garcia G, Ohno M, Lanaspa MA, Johnson RJ.

Am J Nephrol. 2017;45(4):330-337. doi: 10.1159/000464260. Epub 2017 Mar 11.

20.

Circulating IL-6 upregulates IL-10 production in splenic CD4+ T cells and limits acute kidney injury-induced lung inflammation.

Andres-Hernando A, Okamura K, Bhargava R, Kiekhaefer CM, Soranno D, Kirkbride-Romeo LA, Gil HW, Altmann C, Faubel S.

Kidney Int. 2017 May;91(5):1057-1069. doi: 10.1016/j.kint.2016.12.014. Epub 2017 Feb 14.

PMID:
28214022
21.

Dietary and commercialized fructose: Sweet or sour?

Yerlikaya A, Dagel T, King C, Kuwabara M, Lanaspa MA, Andres-Hernando A, Covic A, Manitius J, Sag AA, Kanbay M.

Int Urol Nephrol. 2017 Sep;49(9):1611-1620. doi: 10.1007/s11255-017-1544-8. Epub 2017 Feb 16. Review. Erratum in: Int Urol Nephrol. 2017 Apr 5;:.

PMID:
28210913
22.

Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice.

Andres-Hernando A, Li N, Cicerchi C, Inaba S, Chen W, Roncal-Jimenez C, Le MT, Wempe MF, Milagres T, Ishimoto T, Fini M, Nakagawa T, Johnson RJ, Lanaspa MA.

Nat Commun. 2017 Feb 13;8:14181. doi: 10.1038/ncomms14181.

23.

Increased Serum Sodium and Serum Osmolarity Are Independent Risk Factors for Developing Chronic Kidney Disease; 5 Year Cohort Study.

Kuwabara M, Hisatome I, Roncal-Jimenez CA, Niwa K, Andres-Hernando A, Jensen T, Bjornstad P, Milagres T, Cicerchi C, Song Z, Garcia G, Sánchez-Lozada LG, Ohno M, Lanaspa MA, Johnson RJ.

PLoS One. 2017 Jan 12;12(1):e0169137. doi: 10.1371/journal.pone.0169137. eCollection 2017. Erratum in: PLoS One. 2018 May 17;13(5):e0197941.

24.

Effects of exogenous desmopressin on a model of heat stress nephropathy in mice.

Roncal-Jimenez CA, Milagres T, Andres-Hernando A, Kuwabara M, Jensen T, Song Z, Bjornstad P, Garcia GE, Sato Y, Sanchez-Lozada LG, Lanaspa MA, Johnson RJ.

Am J Physiol Renal Physiol. 2017 Mar 1;312(3):F418-F426. doi: 10.1152/ajprenal.00495.2016. Epub 2016 Dec 21.

25.

Role of fructose and fructokinase in acute dehydration-induced vasopressin gene expression and secretion in mice.

Song 宋志林 Z, Roncal-Jimenez CA, Lanaspa-Garcia MA, Oppelt SA, Kuwabara M, Jensen T, Milagres T, Andres-Hernando A, Ishimoto T, Garcia GE, Johnson G, MacLean PS, Sanchez-Lozada LG, Tolan DR, Johnson RJ.

J Neurophysiol. 2017 Feb 1;117(2):646-654. doi: 10.1152/jn.00781.2016. Epub 2016 Nov 16.

26.

Climate Change and the Emergent Epidemic of CKD from Heat Stress in Rural Communities: The Case for Heat Stress Nephropathy.

Glaser J, Lemery J, Rajagopalan B, Diaz HF, García-Trabanino R, Taduri G, Madero M, Amarasinghe M, Abraham G, Anutrakulchai S, Jha V, Stenvinkel P, Roncal-Jimenez C, Lanaspa MA, Correa-Rotter R, Sheikh-Hamad D, Burdmann EA, Andres-Hernando A, Milagres T, Weiss I, Kanbay M, Wesseling C, Sánchez-Lozada LG, Johnson RJ.

Clin J Am Soc Nephrol. 2016 Aug 8;11(8):1472-83. doi: 10.2215/CJN.13841215. Epub 2016 May 5. Review.

27.

Delivery of interleukin-10 via injectable hydrogels improves renal outcomes and reduces systemic inflammation following ischemic acute kidney injury in mice.

Soranno DE, Rodell CB, Altmann C, Duplantis J, Andres-Hernando A, Burdick JA, Faubel S.

Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F362-72. doi: 10.1152/ajprenal.00579.2015. Epub 2016 Mar 9.

28.

Prolonged acute kidney injury exacerbates lung inflammation at 7 days post-acute kidney injury.

Andres-Hernando A, Altmann C, Bhargava R, Okamura K, Bacalja J, Hunter B, Ahuja N, Soranno D, Faubel S.

Physiol Rep. 2014 Jul 22;2(7). pii: e12084. doi: 10.14814/phy2.12084. Print 2014 Jul 1.

29.

Endogenous fructose production and fructokinase activation mediate renal injury in diabetic nephropathy.

Lanaspa MA, Ishimoto T, Cicerchi C, Tamura Y, Roncal-Jimenez CA, Chen W, Tanabe K, Andres-Hernando A, Orlicky DJ, Finol E, Inaba S, Li N, Rivard CJ, Kosugi T, Sanchez-Lozada LG, Petrash JM, Sautin YY, Ejaz AA, Kitagawa W, Garcia GE, Bonthron DT, Asipu A, Diggle CP, Rodriguez-Iturbe B, Nakagawa T, Johnson RJ.

J Am Soc Nephrol. 2014 Nov;25(11):2526-38. doi: 10.1681/ASN.2013080901. Epub 2014 May 29.

30.

Acute lung injury and acute kidney injury are established by four hours in experimental sepsis and are improved with pre, but not post, sepsis administration of TNF-α antibodies.

Bhargava R, Altmann CJ, Andres-Hernando A, Webb RG, Okamura K, Yang Y, Falk S, Schmidt EP, Faubel S.

PLoS One. 2013 Nov 12;8(11):e79037. doi: 10.1371/journal.pone.0079037. eCollection 2013.

31.

Intratracheal IL-6 protects against lung inflammation in direct, but not indirect, causes of acute lung injury in mice.

Bhargava R, Janssen W, Altmann C, Andrés-Hernando A, Okamura K, Vandivier RW, Ahuja N, Faubel S.

PLoS One. 2013 May 8;8(5):e61405. doi: 10.1371/journal.pone.0061405. Print 2013.

32.

Inorganic phosphate modulates the expression of the NaPi-2a transporter in the trans-Golgi network and the interaction with PIST in the proximal tubule.

Lanaspa MA, Caldas YA, Breusegem SY, Andrés-Hernando A, Cicerchi C, Levi M, Sorribas V.

Biomed Res Int. 2013;2013:513932. doi: 10.1155/2013/513932. Epub 2013 Feb 14.

33.

Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver.

Lanaspa MA, Cicerchi C, Garcia G, Li N, Roncal-Jimenez CA, Rivard CJ, Hunter B, Andrés-Hernando A, Ishimoto T, Sánchez-Lozada LG, Thomas J, Hodges RS, Mant CT, Johnson RJ.

PLoS One. 2012;7(11):e48801. doi: 10.1371/journal.pone.0048801. Epub 2012 Nov 9.

34.

Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver.

Lanaspa MA, Sanchez-Lozada LG, Cicerchi C, Li N, Roncal-Jimenez CA, Ishimoto T, Le M, Garcia GE, Thomas JB, Rivard CJ, Andres-Hernando A, Hunter B, Schreiner G, Rodriguez-Iturbe B, Sautin YY, Johnson RJ.

PLoS One. 2012;7(10):e47948. doi: 10.1371/journal.pone.0047948. Epub 2012 Oct 24.

35.

Circulating IL-6 mediates lung injury via CXCL1 production after acute kidney injury in mice.

Ahuja N, Andres-Hernando A, Altmann C, Bhargava R, Bacalja J, Webb RG, He Z, Edelstein CL, Faubel S.

Am J Physiol Renal Physiol. 2012 Sep 15;303(6):F864-72. doi: 10.1152/ajprenal.00025.2012. Epub 2012 Jul 11.

36.

Cytokine production increases and cytokine clearance decreases in mice with bilateral nephrectomy.

Andres-Hernando A, Dursun B, Altmann C, Ahuja N, He Z, Bhargava R, Edelstein CE, Jani A, Hoke TS, Klein C, Faubel S.

Nephrol Dial Transplant. 2012 Dec;27(12):4339-47. doi: 10.1093/ndt/gfs256. Epub 2012 Jul 9.

37.

Depletion of macrophages and dendritic cells in ischemic acute kidney injury.

Lu L, Faubel S, He Z, Andres Hernando A, Jani A, Kedl R, Edelstein CL.

Am J Nephrol. 2012;35(2):181-90. doi: 10.1159/000335582. Epub 2012 Jan 25.

38.

Macrophages mediate lung inflammation in a mouse model of ischemic acute kidney injury.

Altmann C, Andres-Hernando A, McMahan RH, Ahuja N, He Z, Rivard CJ, Edelstein CL, Barthel L, Janssen WJ, Faubel S.

Am J Physiol Renal Physiol. 2012 Feb 15;302(4):F421-32. doi: 10.1152/ajprenal.00559.2010. Epub 2011 Nov 23.

39.

Splenectomy exacerbates lung injury after ischemic acute kidney injury in mice.

Andrés-Hernando A, Altmann C, Ahuja N, Lanaspa MA, Nemenoff R, He Z, Ishimoto T, Simpson PA, Weiser-Evans MC, Bacalja J, Faubel S.

Am J Physiol Renal Physiol. 2011 Oct;301(4):F907-16. doi: 10.1152/ajprenal.00107.2011. Epub 2011 Jun 15.

40.

Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake.

Roncal-Jimenez CA, Lanaspa MA, Rivard CJ, Nakagawa T, Sanchez-Lozada LG, Jalal D, Andres-Hernando A, Tanabe K, Madero M, Li N, Cicerchi C, Mc Fann K, Sautin YY, Johnson RJ.

Metabolism. 2011 Sep;60(9):1259-70. doi: 10.1016/j.metabol.2011.01.008. Epub 2011 Apr 12.

41.

Urine interleukin-6 is an early biomarker of acute kidney injury in children undergoing cardiac surgery.

Dennen P, Altmann C, Kaufman J, Klein CL, Andres-Hernando A, Ahuja NH, Edelstein CL, Cadnapaphornchai MA, Keniston A, Faubel S.

Crit Care. 2010;14(5):R181. doi: 10.1186/cc9289. Epub 2010 Oct 13.

42.

Effects of 2-bromoethanamine on TonEBP expression and its possible role in induction of renal papillary necrosis in mice.

Andres-Hernando A, Lanaspa MA, Li N, Cicerchi C, Roncal-Jimenez C, Cantor GH, Sorribas V, Rivard CJ, Berl T.

Toxicol Sci. 2010 Dec;118(2):510-20. doi: 10.1093/toxsci/kfq261. Epub 2010 Sep 7.

43.

The expression of aquaporin-1 in the medulla of the kidney is dependent on the transcription factor associated with hypertonicity, TonEBP.

Lanaspa MA, Andres-Hernando A, Li N, Rivard CJ, Cicerchi C, Roncal-Jimenez C, Schrier RW, Berl T.

J Biol Chem. 2010 Oct 8;285(41):31694-703. doi: 10.1074/jbc.M109.093690. Epub 2010 Jul 16.

44.

ZAC1 is up-regulated by hypertonicity and decreases sorbitol dehydrogenase expression, allowing accumulation of sorbitol in kidney cells.

Lanaspa MA, Andres-Hernando A, Rivard CJ, Dai Y, Li N, Berl T.

J Biol Chem. 2009 Jul 24;284(30):19974-81. doi: 10.1074/jbc.M109.001792. Epub 2009 May 7.

45.

Hypertonic stress increases claudin-4 expression and tight junction integrity in association with MUPP1 in IMCD3 cells.

Lanaspa MA, Andres-Hernando A, Rivard CJ, Dai Y, Berl T.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15797-802. doi: 10.1073/pnas.0805761105. Epub 2008 Oct 7.

46.

Nucleoporin 88 (Nup88) is regulated by hypertonic stress in kidney cells to retain the transcription factor tonicity enhancer-binding protein (TonEBP) in the nucleus.

Andres-Hernando A, Lanaspa MA, Rivard CJ, Berl T.

J Biol Chem. 2008 Sep 5;283(36):25082-90. doi: 10.1074/jbc.M802381200. Epub 2008 Jul 7.

47.

The tight junction protein, MUPP1, is up-regulated by hypertonicity and is important in the osmotic stress response in kidney cells.

Lanaspa MA, Almeida NE, Andres-Hernando A, Rivard CJ, Capasso JM, Berl T.

Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13672-7. Epub 2007 Aug 9.

48.

Expression of the calcium-binding protein S100A4 is markedly up-regulated by osmotic stress and is involved in the renal osmoadaptive response.

Rivard CJ, Brown LM, Almeida NE, Maunsbach AB, Pihakaski-Maunsbach K, Andres-Hernando A, Capasso JM, Berl T.

J Biol Chem. 2007 Mar 2;282(9):6644-52. Epub 2007 Jan 2.

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