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Items: 1 to 50 of 342

1.

CRISPR/Cas9 Editing of the Polyomavirus Tumor Antigens Inhibits Merkel Cell Carcinoma Growth In Vitro.

Temblador A, Topalis D, Andrei G, Snoeck R.

Cancers (Basel). 2019 Aug 28;11(9). pii: E1260. doi: 10.3390/cancers11091260.

2.

Meeting report: 32nd International Conference on Antiviral Research.

Tramontano E, Tarbet B, Spengler JR, Seley-Radtke K, Meier C, Jordan R, Janeba Z, Gowen B, Gentry B, Esté JA, Bray M, Andrei G, Schang LM; International Society for Antiviral Research.

Antiviral Res. 2019 Sep;169:104550. doi: 10.1016/j.antiviral.2019.104550. Epub 2019 Jul 11. Review.

PMID:
31302149
3.

Persistent primary cytomegalovirus infection in a kidney transplant recipient: Multi-drug resistant and compartmentalized infection leading to graft loss.

Andrei G, Van Loon E, Lerut E, Victoor J, Meijers B, Bammens B, Sprangers B, Gillemot S, Fiten P, Opdenakker G, Lagrou K, Kuypers D, Snoeck R, Naesens M.

Antiviral Res. 2019 Aug;168:203-209. doi: 10.1016/j.antiviral.2019.06.004. Epub 2019 Jun 15.

PMID:
31212020
4.

Novel Therapeutics for Epstein⁻Barr Virus.

Andrei G, Trompet E, Snoeck R.

Molecules. 2019 Mar 12;24(5). pii: E997. doi: 10.3390/molecules24050997. Review.

5.

Design, Synthesis, and Biological Evaluation of Novel C5-Modified Pyrimidine Ribofuranonucleosides as Potential Antitumor or/and Antiviral Agents.

Kollatos N, Mitsos C, Manta S, Tzioumaki N, Giannakas C, Alexouli T, Panagiotopoulou A, Schols D, Andrei G, Komioti D.

Med Chem. 2019 Feb 24. doi: 10.2174/1573406415666190225112950. [Epub ahead of print]

PMID:
30799795
6.

Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives.

Mohammed AF, Andrei G, Hayallah AM, Abdel-Moty SG, Snoeck R, Simons C.

Bioorg Med Chem. 2019 Mar 15;27(6):1023-1033. doi: 10.1016/j.bmc.2019.02.005. Epub 2019 Feb 2.

PMID:
30738653
7.

Antiviral activity spectrum of phenoxazine nucleoside derivatives.

Kozlovskaya LI, Andrei G, Orlov AA, Khvatov EV, Koruchekov AA, Belyaev ES, Nikolaev EN, Korshun VA, Snoeck R, Osolodkin DI, Matyugina ES, Aralov AV.

Antiviral Res. 2019 Mar;163:117-124. doi: 10.1016/j.antiviral.2019.01.010. Epub 2019 Jan 23.

PMID:
30684562
8.

Utilization of 1,3-Dioxolanes in the Synthesis of α-branched Alkyl and Aryl 9-[2-(Phosphonomethoxy)Ethyl]Purines and Study of the Influence of α-branched Substitution for Potential Biological Activity.

Pomeisl K, Pohl R, Snoeck R, Andrei G, Krečmerová M.

Nucleosides Nucleotides Nucleic Acids. 2019;38(2):119-156. doi: 10.1080/15257770.2018.1506884. Epub 2018 Dec 7.

PMID:
30526265
9.

Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus.

Baszczyňski O, Kaiser MM, Česnek M, Břehová P, Jansa P, Procházková E, Dračínský M, Snoeck R, Andrei G, Janeba Z.

Antivir Chem Chemother. 2018 Jan-Dec;26:2040206618813050. doi: 10.1177/2040206618813050.

10.

Synthesis, Anti-varicella-zoster virus and Anti-cytomegalovirus Activity of 4,5-Disubstituted 1,2,3-(1H)-Triazoles.

Yuan WY, Chen X, Liu NN, Wen YN, Yang B, Andrei G, Snoeck R, Xiang YH, Wu YW, Jiang Z, Schols D, Zhang ZY, Wu QP.

Med Chem. 2018 Nov 8. doi: 10.2174/1573406414666181109095239. [Epub ahead of print]

PMID:
30411688
11.

Synthesis of a 3'-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides.

Hulpia F, Noppen S, Schols D, Andrei G, Snoeck R, Liekens S, Vervaeke P, Van Calenbergh S.

Eur J Med Chem. 2018 Sep 5;157:248-267. doi: 10.1016/j.ejmech.2018.07.062. Epub 2018 Jul 29.

PMID:
30098481
12.

Meeting report: 31st International Conference on Antiviral Research.

Bray M, Andrei G, Ballana E, Carter K, Durantel D, Gentry B, Janeba Z, Moffat J, Oomen CJ, Tarbet B, Riveira-Muñoz E, Esté JA; International Society for Antiviral Research.

Antiviral Res. 2018 Oct;158:88-102. doi: 10.1016/j.antiviral.2018.08.002. Epub 2018 Aug 4. Review.

PMID:
30086336
13.

Isoxazolidine Conjugates of N3-Substituted 6-Bromoquinazolinones-Synthesis, Anti-Varizella-Zoster Virus, and Anti-Cytomegalovirus Activity.

Grabkowska-Drużyc M, Andrei G, Schols D, Snoeck R, Piotrowska DG.

Molecules. 2018 Jul 28;23(8). pii: E1889. doi: 10.3390/molecules23081889.

14.

Dihydropyrimidinone/1,2,3-triazole hybrid molecules: Synthesis and anti-varicella-zoster virus (VZV) evaluation.

Kaoukabi H, Kabri Y, Curti C, Taourirte M, Rodriguez-Ubis JC, Snoeck R, Andrei G, Vanelle P, Lazrek HB.

Eur J Med Chem. 2018 Jul 15;155:772-781. doi: 10.1016/j.ejmech.2018.06.028. Epub 2018 Jun 13.

PMID:
29945100
15.

Antiviral Drugs for EBV.

Pagano JS, Whitehurst CB, Andrei G.

Cancers (Basel). 2018 Jun 13;10(6). pii: E197. doi: 10.3390/cancers10060197.

16.

Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs.

Pileggi E, Serpi M, Andrei G, Schols D, Snoeck R, Pertusati F.

Bioorg Med Chem. 2018 Jul 23;26(12):3596-3609. doi: 10.1016/j.bmc.2018.05.034. Epub 2018 May 23.

PMID:
29880251
17.

Varicella-Zoster Virus ORF9p Binding to Cellular Adaptor Protein Complex 1 Is Important for Viral Infectivity.

Lebrun M, Lambert J, Riva L, Thelen N, Rambout X, Blondeau C, Thiry M, Snoeck R, Twizere JC, Dequiedt F, Andrei G, Sadzot-Delvaux C.

J Virol. 2018 Jul 17;92(15). pii: e00295-18. doi: 10.1128/JVI.00295-18. Print 2018 Aug 1.

18.

Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.

Mertens B, Cristina de Araujo Nogueira T, Topalis D, Stranska R, Snoeck R, Andrei G.

Oncotarget. 2018 Apr 24;9(31):21978-22000. doi: 10.18632/oncotarget.25140. eCollection 2018 Apr 24.

19.

Amidate Prodrugs of Cyclic 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine with Potent Anti-Herpesvirus Activity.

Luo M, Groaz E, De Jonghe S, Snoeck R, Andrei G, Herdewijn P.

ACS Med Chem Lett. 2018 Mar 16;9(4):381-385. doi: 10.1021/acsmedchemlett.8b00079. eCollection 2018 Apr 12.

20.

Synthesis and antiviral evaluation of cyclopentyl nucleoside phosphonates.

Wang M, Srivastava P, Liu C, Snoeck R, Andrei G, De Jonghe S, Herdewijn P.

Eur J Med Chem. 2018 Apr 25;150:616-625. doi: 10.1016/j.ejmech.2018.03.008. Epub 2018 Mar 10.

PMID:
29550734
21.

Thymidine kinase and protein kinase in drug-resistant herpesviruses: Heads of a Lernaean Hydra.

Topalis D, Gillemot S, Snoeck R, Andrei G.

Drug Resist Updat. 2018 Mar;37:1-16. doi: 10.1016/j.drup.2018.01.003. Epub 2018 Jan 31. Review.

PMID:
29548479
22.

Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates.

Bessières M, Hervin V, Roy V, Chartier A, Snoeck R, Andrei G, Lohier JF, Agrofoglio LA.

Eur J Med Chem. 2018 Feb 25;146:678-686. doi: 10.1016/j.ejmech.2018.01.086. Epub 2018 Jan 31.

PMID:
29407990
23.

Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma.

Stranska R, Gysbrechts L, Wouters J, Vermeersch P, Bloch K, Dierickx D, Andrei G, Snoeck R.

J Transl Med. 2018 Jan 9;16(1):1. doi: 10.1186/s12967-017-1374-6.

24.

Auspicious Management of a Acute Obstructive Left Colon Tumor in a 93-year-old Patient - Case Report and Literature Review.

Andrei GN, Constantinescu G, Nedelcu C, Dumitriu BC, Valcea S, Beuran M.

Chirurgia (Bucur). 2017 Nov-Dec;112(6):734-746. doi: 10.21614/chirurgia.112.6.734. Review.

25.

Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.

Plebanek E, Lescrinier E, Andrei G, Snoeck R, Herdewijn P, De Jonghe S.

Eur J Med Chem. 2018 Jan 20;144:93-103. doi: 10.1016/j.ejmech.2017.12.018. Epub 2017 Dec 7.

PMID:
29268134
26.

Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis.

Brisse E, Imbrechts M, Mitera T, Vandenhaute J, Wouters CH, Snoeck R, Andrei G, Matthys P.

Virol J. 2017 Dec 19;14(1):240. doi: 10.1186/s12985-017-0908-0.

27.

The Anti-Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase.

Andrei G, Gillemot S, Topalis D, Snoeck R.

J Infect Dis. 2018 Feb 14;217(5):790-801. doi: 10.1093/infdis/jix605.

PMID:
29186456
28.

Lymphocyte-independent pathways underlie the pathogenesis of murine cytomegalovirus-associated secondary haemophagocytic lymphohistiocytosis.

Brisse E, Imbrechts M, Mitera T, Vandenhaute J, Berghmans N, Boon L, Wouters C, Snoeck R, Andrei G, Matthys P.

Clin Exp Immunol. 2018 Apr;192(1):104-119. doi: 10.1111/cei.13084. Epub 2018 Jan 18.

29.

A European multi-centre External Quality Assessment (EQA) study on phenotypic and genotypic methods used for Herpes Simplex Virus (HSV) drug resistance testing.

Afshar B, Bibby DF, Piorkowska R, Ohemeng-Kumi N, Snoeck R, Andrei G, Gillemot S, Morfin F, Frobert E, Burrel S, Boutolleau D, Crowley B, Mbisa JL.

J Clin Virol. 2017 Nov;96:89-93. doi: 10.1016/j.jcv.2017.10.002. Epub 2017 Oct 6.

PMID:
29031157
30.

How Viruses Contribute to the Pathogenesis of Hemophagocytic Lymphohistiocytosis.

Brisse E, Wouters CH, Andrei G, Matthys P.

Front Immunol. 2017 Sep 7;8:1102. doi: 10.3389/fimmu.2017.01102. eCollection 2017.

31.

Virtual Screening of Acyclovir Derivatives as Potential Antiviral Agents: Design, Synthesis, and Biological Evaluation of New Acyclic Nucleoside ProTides.

Derudas M, Vanpouille C, Carta D, Zicari S, Andrei G, Snoeck R, Brancale A, Margolis L, Balzarini J, McGuigan C.

J Med Chem. 2017 Sep 28;60(18):7876-7896. doi: 10.1021/acs.jmedchem.7b01009. Epub 2017 Sep 19.

32.

Highlights of the 30th International Conference on Antiviral Research.

Andrei G, Carter K, Janeba Z, Sampath A, Schang LM, Tarbet EB, Vere Hodge RA, Bray M, Esté JA.

Antiviral Res. 2017 Sep;145:184-196. doi: 10.1016/j.antiviral.2017.07.017. Epub 2017 Aug 1.

PMID:
28774800
33.

Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3-Triazole Nucleosides.

Głowacka IE, Andrei G, Schols D, Snoeck R, Gawron K.

Arch Pharm (Weinheim). 2017 Sep;350(9). doi: 10.1002/ardp.201700166. Epub 2017 Aug 1.

PMID:
28763115
34.

New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity.

Krečmerová M, Dračínský M, Snoeck R, Balzarini J, Pomeisl K, Andrei G.

Bioorg Med Chem. 2017 Sep 1;25(17):4637-4648. doi: 10.1016/j.bmc.2017.06.046. Epub 2017 Jul 6.

PMID:
28757102
35.

Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.

Luo M, Groaz E, Andrei G, Snoeck R, Kalkeri R, Ptak RG, Hartman T, Buckheit RW Jr, Schols D, De Jonghe S, Herdewijn P.

J Med Chem. 2017 Jul 27;60(14):6220-6238. doi: 10.1021/acs.jmedchem.7b00416. Epub 2017 Jul 6.

PMID:
28682067
36.

Phosphonoamidate prodrugs of C5-substituted pyrimidine acyclic nucleosides for antiviral therapy.

Pertusati F, Serafini S, Albadry N, Snoeck R, Andrei G.

Antiviral Res. 2017 Jul;143:262-268. doi: 10.1016/j.antiviral.2017.04.013. Epub 2017 Apr 25.

PMID:
28454912
37.

Antiviral and Cytostatic Evaluation of 5-(1-Halo-2-sulfonylvinyl)- and 5-(2-Furyl)uracil Nucleosides.

Wen Z, Suzol SH, Peng J, Liang Y, Snoeck R, Andrei G, Liekens S, Wnuk SF.

Arch Pharm (Weinheim). 2017 Apr;350(3-4). doi: 10.1002/ardp.201700023. Epub 2017 Mar 17.

PMID:
28304114
38.

Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).

Wen YN, Zhang ZF, Liu NN, Andrei G, Snoeck R, Xiang YH, Schols D, Chen X, Zhang ZY, Zhang QS, Wu QP.

Med Chem. 2017;13(5):453-464. doi: 10.2174/1573406413666170307165236.

PMID:
28290250
39.
40.
41.

Acyclic nucleoside phosphonates containing the amide bond.

Głowacka IE, Piotrowska DG, Andrei G, Schols D, Snoeck R, Wróblewski AE.

Monatsh Chem. 2016;147(12):2163-2177. Epub 2016 Oct 26.

42.

Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates.

Głowacka IE, Gulej R, Grzonkowski P, Andrei G, Schols D, Snoeck R, Piotrowska DG.

Molecules. 2016 Oct 26;21(11). pii: E1420.

43.

Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures.

Piotrowska DG, Andrei G, Schols D, Snoeck R, Łysakowska M.

Eur J Med Chem. 2017 Jan 27;126:84-100. doi: 10.1016/j.ejmech.2016.10.002. Epub 2016 Oct 4.

PMID:
27750154
44.

Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase.

Topalis D, Gillemot S, Snoeck R, Andrei G.

Nucleic Acids Res. 2016 Nov 16;44(20):9530-9554. Epub 2016 Sep 29. Review.

45.

Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor.

Musella S, di Sarno V, Ciaglia T, Sala M, Spensiero A, Scala MC, Ostacolo C, Andrei G, Balzarini J, Snoeck R, Novellino E, Campiglia P, Bertamino A, Gomez-Monterrey IM.

Eur J Med Chem. 2016 Nov 29;124:773-781. doi: 10.1016/j.ejmech.2016.09.014. Epub 2016 Sep 7.

PMID:
27639368
46.

Distinct Effects of T-705 (Favipiravir) and Ribavirin on Influenza Virus Replication and Viral RNA Synthesis.

Vanderlinden E, Vrancken B, Van Houdt J, Rajwanshi VK, Gillemot S, Andrei G, Lemey P, Naesens L.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6679-6691. doi: 10.1128/AAC.01156-16. Print 2016 Nov.

47.

New Isoxazolidine-Conjugates of Quinazolinones-Synthesis, Antiviral and Cytostatic Activity.

Piotrowska DG, Andrei G, Schols D, Snoeck R, Grabkowska-Drużyc M.

Molecules. 2016 Jul 22;21(7). pii: E959. doi: 10.3390/molecules21070959.

48.

Isolated Ileum Perforation Following Veal Attack in a Pacient with an Undiagnosed Inguinal Hernia: Case Report and Review of the Literature.

Andrei GN, Diaconescu BI, Martian BV, Beuran M.

Chirurgia (Bucur). 2016 May-Jun;111(3):266-9. Review.

49.

Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms.

Mertens B, Nogueira T, Stranska R, Naesens L, Andrei G, Snoeck R.

Oncotarget. 2016 Jul 26;7(30):47302-47318. doi: 10.18632/oncotarget.10100.

50.

Multidrug-resistant cytomegalovirus infection in a pediatric stem cell transplantation patient.

Bauters T, Bordon V, Florin L, Padalko E, Andrei G, Gillemot S, Fiten P, Opdenakker G, Snoeck R, Laureys G.

Antiviral Res. 2016 Aug;132:149-53. doi: 10.1016/j.antiviral.2016.05.020. Epub 2016 Jun 11. No abstract available.

PMID:
27296901

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