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Physical Determinants of Amyloid Assembly in Biofilm Formation.

Andreasen M, Meisl G, Taylor JD, Michaels TCT, Levin A, Otzen DE, Chapman MR, Dobson CM, Matthews SJ, Knowles TPJ.

MBio. 2019 Jan 8;10(1). pii: e02279-18. doi: 10.1128/mBio.02279-18.


Use of alternative medicine, ginger and licorice among Danish pregnant women - a prospective cohort study.

Volqvartz T, Vestergaard AL, Aagaard SK, Andreasen MF, Lesnikova I, Uldbjerg N, Larsen A, Bor P.

BMC Complement Altern Med. 2019 Jan 5;19(1):5. doi: 10.1186/s12906-018-2419-y.


Role of GABAB receptors in proepileptic and antiepileptic effects of an applied electric field in rat hippocampus in vitro.

Svejgaard B, Andreasen M, Nedergaard S.

Brain Res. 2018 Dec 29. pii: S0006-8993(18)30669-3. doi: 10.1016/j.brainres.2018.12.043. [Epub ahead of print]


Imperfect repeats in the functional amyloid protein FapC reduce the tendency to fragment during fibrillation.

Rasmussen CB, Christiansen G, Vad BS, Lynggaard C, Enghild JJ, Andreasen M, Otzen D.

Protein Sci. 2018 Dec 28. doi: 10.1002/pro.3566. [Epub ahead of print]


Remote optimization of an ultracold atoms experiment by experts and citizen scientists.

Heck R, Vuculescu O, Sørensen JJ, Zoller J, Andreasen MG, Bason MG, Ejlertsen P, Elíasson O, Haikka P, Laustsen JS, Nielsen LL, Mao A, Müller R, Napolitano M, Pedersen MK, Thorsen AR, Bergenholtz C, Calarco T, Montangero S, Sherson JF.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11231-E11237. doi: 10.1073/pnas.1716869115. Epub 2018 Nov 9.


Postmortem analysis of three methoxyacetylfentanyl-related deaths in Denmark and in vitro metabolite profiling in pooled human hepatocytes.

Mardal M, Johansen SS, Davidsen AB, Telving R, Jornil JR, Dalsgaard PW, Hasselstrøm JB, Øiestad ÅM, Linnet K, Andreasen MF.

Forensic Sci Int. 2018 Sep;290:310-317. doi: 10.1016/j.forsciint.2018.07.020. Epub 2018 Jul 25.


Implementation of triple the time spent on physical education in pre-school to 6th grade: A qualitative study from the programme managers' perspective.

Nielsen JV, Klakk H, Bugge A, Andreasen ML, Skovgaard T.

Eval Program Plann. 2018 Oct;70:51-60. doi: 10.1016/j.evalprogplan.2018.06.001. Epub 2018 Jun 19.


Corneal Dystrophy Mutations Drive Pathogenesis by Targeting TGFBIp Stability and Solubility in a Latent Amyloid-forming Domain.

Stenvang M, Schafer NP, Malmos KG, Pérez AW, Niembro O, Sormanni P, Basaiawmoit RV, Christiansen G, Andreasen M, Otzen DE.

J Mol Biol. 2018 Apr 13;430(8):1116-1140. doi: 10.1016/j.jmb.2018.03.001. Epub 2018 Mar 7.


Prevalence of xenobiotic substances in first-trimester blood samples from Danish pregnant women: a cross-sectional study.

Aagaard SK, Larsen A, Andreasen MF, Lesnikova I, Telving R, Vestergaard AL, Tørring N, Uldbjerg N, Bor P.

BMJ Open. 2018 Mar 3;8(3):e018390. doi: 10.1136/bmjopen-2017-018390.


Opposing effects of 2-deoxy-d-glucose on interictal- and ictal-like activity when K+ currents and GABAA receptors are blocked in rat hippocampus in vitro.

Nedergaard S, Andreasen M.

J Neurophysiol. 2018 May 1;119(5):1912-1923. doi: 10.1152/jn.00732.2017. Epub 2018 Feb 7.


Corrigendum: The Coral Trait Database, a curated database of trait information for coral species from the global oceans.

Madin JS, Anderson KD, Andreasen MH, Bridge TCL, Cairns SD, Connolly SR, Darling ES, Diaz M, Falster DS, Franklin EC, Gates RD, Harmer AMT, Hoogenboom MO, Huang D, Keith SA, Kosnik MA, Kuo CY, Lough JM, Lovelock CE, Luiz O, Martinelli J, Mizerek T, Pandolfi JM, Pochon X, Pratchett MS, Putnam HM, Roberts TE, Stat M, Wallace CC, Widman E, Baird AH.

Sci Data. 2017 Dec 5;4:170174. doi: 10.1038/sdata.2017.174.


Absolute Quantification of Amyloid Propagons by Digital Microfluidics.

Pfammatter M, Andreasen M, Meisl G, Taylor CG, Adamcik J, Bolisetty S, Sánchez-Ferrer A, Klenerman D, Dobson CM, Mezzenga R, Knowles TPJ, Aguzzi A, Hornemann S.

Anal Chem. 2017 Nov 21;89(22):12306-12313. doi: 10.1021/acs.analchem.7b03279. Epub 2017 Nov 1.


Recreational drug use at a major music festival: trend analysis of anonymised pooled urine.

Hoegberg LCG, Christiansen C, Soe J, Telving R, Andreasen MF, Staerk D, Christrup LL, Kongstad KT.

Clin Toxicol (Phila). 2018 Apr;56(4):245-255. doi: 10.1080/15563650.2017.1360496. Epub 2017 Aug 17.


Assessment of the Risk to Public Health due to Use of Antimicrobials in Pigs-An Example of Pleuromutilins in Denmark.

Alban L, Ellis-Iversen J, Andreasen M, Dahl J, Sönksen UW.

Front Vet Sci. 2017 May 26;4:74. doi: 10.3389/fvets.2017.00074. eCollection 2017.


[Use of complementary and herbal medicine in the general population and among pregnant women].

Aagaard SK, Larsen A, Andreasen MF, Uldbjerg N, Bor P.

Ugeskr Laeger. 2017 Jan 30;179(5). pii: V08160586. Review. Danish.


Furosemide depresses the presynaptic fiber volley and modifies frequency-dependent axonal excitability in rat hippocampus.

Andreasen M, Nedergaard S.

J Neurophysiol. 2017 Apr 1;117(4):1512-1523. doi: 10.1152/jn.00704.2016. Epub 2017 Jan 18.


Cognitive deficits caused by a disease-mutation in the α3 Na(+)/K(+)-ATPase isoform.

Holm TH, Isaksen TJ, Glerup S, Heuck A, Bøttger P, Füchtbauer EM, Nedergaard S, Nyengaard JR, Andreasen M, Nissen P, Lykke-Hartmann K.

Sci Rep. 2016 Aug 23;6:31972. doi: 10.1038/srep31972.


Identification of a new psychoactive substance in seized material: the synthetic opioid N-phenyl-N-[1-(2-phenethyl)piperidin-4-yl]prop-2-enamide (Acrylfentanyl).

Breindahl T, Kimergård A, Andreasen MF, Pedersen DS.

Drug Test Anal. 2017 Mar;9(3):415-422. doi: 10.1002/dta.2046. Epub 2016 Aug 24.


Targeted toxicological screening for acidic, neutral and basic substances in postmortem and antemortem whole blood using simple protein precipitation and UPLC-HR-TOF-MS.

Telving R, Hasselstrøm JB, Andreasen MF.

Forensic Sci Int. 2016 Sep;266:453-461. doi: 10.1016/j.forsciint.2016.07.004. Epub 2016 Jul 18.


Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones.

Taylor JD, Hawthorne WJ, Lo J, Dear A, Jain N, Meisl G, Andreasen M, Fletcher C, Koch M, Darvill N, Scull N, Escalera-Maurer A, Sefer L, Wenman R, Lambert S, Jean J, Xu Y, Turner B, Kazarian SG, Chapman MR, Bubeck D, de Simone A, Knowles TP, Matthews SJ.

Sci Rep. 2016 Apr 21;6:24656. doi: 10.1038/srep24656.


Exploring the quantum speed limit with computer games.

Sørensen JJ, Pedersen MK, Munch M, Haikka P, Jensen JH, Planke T, Andreasen MG, Gajdacz M, Mølmer K, Lieberoth A, Sherson JF.

Nature. 2016 Apr 14;532(7598):210-3. doi: 10.1038/nature17620.


The Coral Trait Database, a curated database of trait information for coral species from the global oceans.

Madin JS, Anderson KD, Andreasen MH, Bridge TC, Cairns SD, Connolly SR, Darling ES, Diaz M, Falster DS, Franklin EC, Gates RD, Harmer A, Hoogenboom MO, Huang D, Keith SA, Kosnik MA, Kuo CY, Lough JM, Lovelock CE, Luiz O, Martinelli J, Mizerek T, Pandolfi JM, Pochon X, Pratchett MS, Putnam HM, Roberts TE, Stat M, Wallace CC, Widman E, Baird AH.

Sci Data. 2016 Mar 29;3:160017. doi: 10.1038/sdata.2016.17. Erratum in: Sci Data. 2017 Dec 05;4:170174. Harmer, Aaron [added].


A Metabolomics Study of Retrospective Forensic Data from Whole Blood Samples of Humans Exposed to 3,4-Methylenedioxymethamphetamine: A New Approach for Identifying Drug Metabolites and Changes in Metabolism Related to Drug Consumption.

Nielsen KL, Telving R, Andreasen MF, Hasselstrøm JB, Johannsen M.

J Proteome Res. 2016 Feb 5;15(2):619-27. doi: 10.1021/acs.jproteome.5b01023. Epub 2016 Jan 8.


A novel mechanism for the anticonvulsant effect of furosemide in rat hippocampus in vitro.

Uwera J, Nedergaard S, Andreasen M.

Brain Res. 2015 Nov 2;1625:1-8. doi: 10.1016/j.brainres.2015.08.014. Epub 2015 Aug 21.


Scaffolded multimers of hIAPP(20-29) peptide fragments fibrillate faster and lead to different fibrils compared to the free hIAPP(20-29) peptide fragment.

Christoffersen HF, Andreasen M, Zhang S, Nielsen EH, Christiansen G, Dong M, Skrydstrup T, Otzen DE.

Biochim Biophys Acta. 2015 Dec;1854(12):1890-1897. doi: 10.1016/j.bbapap.2015.08.005. Epub 2015 Aug 15.


Near-complete 1H, 13C, 15N resonance assignments of dimethylsulfoxide-denatured TGFBIp FAS1-4 A546T.

Kulminskaya NV, Yoshimura Y, Runager K, Sørensen CS, Bjerring M, Andreasen M, Otzen DE, Enghild JJ, Nielsen NC, Mulder FA.

Biomol NMR Assign. 2016 Apr;10(1):25-9. doi: 10.1007/s12104-015-9630-2. Epub 2015 Aug 15.


The use of third and fourth generation cephalosporins affects the occurrence of extended-spectrum cephalosporinase-producing Escherichia coli in Danish pig herds.

Andersen VD, Jensen VF, Vigre H, Andreasen M, Agersø Y.

Vet J. 2015 Jun;204(3):345-50. doi: 10.1016/j.tvjl.2015.03.014. Epub 2015 Mar 16.


Preventing peptide and protein misbehavior.

Arosio P, Meisl G, Andreasen M, Knowles TP.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5267-8. doi: 10.1073/pnas.1505170112. Epub 2015 Apr 20. No abstract available.


A fatal poisoning involving 25C-NBOMe.

Andreasen MF, Telving R, Rosendal I, Eg MB, Hasselstrøm JB, Andersen LV.

Forensic Sci Int. 2015 Jun;251:e1-8. doi: 10.1016/j.forsciint.2015.03.012. Epub 2015 Mar 24.


Interactions between misfolded protein oligomers and membranes: A central topic in neurodegenerative diseases?

Andreasen M, Lorenzen N, Otzen D.

Biochim Biophys Acta. 2015 Sep;1848(9):1897-907. doi: 10.1016/j.bbamem.2015.01.018. Epub 2015 Feb 7. Review.


The importance of being capped: Terminal capping of an amyloidogenic peptide affects fibrillation propensity and fibril morphology.

Andreasen M, Skeby KK, Zhang S, Nielsen EH, Klausen LH, Frahm H, Christiansen G, Skrydstrup T, Dong M, Schiøtt B, Otzen D.

Biochemistry. 2014 Nov 11;53(44):6968-80. doi: 10.1021/bi500674u. Epub 2014 Oct 31.


Intrinsic Ca2+-dependent theta oscillations in apical dendrites of hippocampal CA1 pyramidal cells in vitro.

Hansen AK, Nedergaard S, Andreasen M.

J Neurophysiol. 2014 Aug 1;112(3):631-43. doi: 10.1152/jn.00753.2013. Epub 2014 May 14.


High stability and cooperative unfolding of α-synuclein oligomers.

Paslawski W, Andreasen M, Nielsen SB, Lorenzen N, Thomsen K, Kaspersen JD, Pedersen JS, Otzen DE.

Biochemistry. 2014 Oct 7;53(39):6252-63. doi: 10.1021/bi5007833. Epub 2014 Sep 24.


The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.

Lorenzen N, Nielsen SB, Buell AK, Kaspersen JD, Arosio P, Vad BS, Paslawski W, Christiansen G, Valnickova-Hansen Z, Andreasen M, Enghild JJ, Pedersen JS, Dobson CM, Knowles TP, Otzen DE.

J Am Chem Soc. 2014 Mar 12;136(10):3859-68. doi: 10.1021/ja411577t. Epub 2014 Feb 28.


GM food in the public mind-facts are not what they used to be.

Andreasen M.

Nat Biotechnol. 2014 Jan;32(1):25. doi: 10.1038/nbt.2790. No abstract available.


Suppression of epileptiform activity by a single short-duration electric field in rat hippocampus in vitro.

Mikkelsen R, Andreasen M, Nedergaard S.

J Neurophysiol. 2013 Jun;109(11):2720-31. doi: 10.1152/jn.00887.2012. Epub 2013 Mar 13.


Coexistence of ribbon and helical fibrils originating from hIAPP(20-29) revealed by quantitative nanomechanical atomic force microscopy.

Zhang S, Andreasen M, Nielsen JT, Liu L, Nielsen EH, Song J, Ji G, Sun F, Skrydstrup T, Besenbacher F, Nielsen NC, Otzen DE, Dong M.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2798-803. doi: 10.1073/pnas.1209955110. Epub 2013 Feb 6.


Possible impact of the "yellow card" antimicrobial scheme on meat inspection lesions in Danish finisher pigs.

Alban L, Dahl J, Andreasen M, Petersen JV, Sandberg M.

Prev Vet Med. 2013 Mar 1;108(4):334-41. doi: 10.1016/j.prevetmed.2012.11.010. Epub 2012 Nov 26.


Carriage and fecal counts of cefotaxime M-producing Escherichia coli in pigs: a longitudinal study.

Hansen KH, Damborg P, Andreasen M, Nielsen SS, Guardabassi L.

Appl Environ Microbiol. 2013 Feb;79(3):794-8. doi: 10.1128/AEM.02399-12. Epub 2012 Nov 16. Erratum in: Appl Environ Microbiol. 2013 Mar;79(6):2110.


Polymorphic fibrillation of the destabilized fourth fasciclin-1 domain mutant A546T of the Transforming growth factor-β-induced protein (TGFBIp) occurs through multiple pathways with different oligomeric intermediates.

Andreasen M, Nielsen SB, Runager K, Christiansen G, Nielsen NC, Enghild JJ, Otzen DE.

J Biol Chem. 2012 Oct 5;287(41):34730-42. doi: 10.1074/jbc.M112.379552. Epub 2012 Aug 14.


Screening analysis for medicinal drugs and drugs of abuse in whole blood using ultra-performance liquid chromatography time-of-flight mass spectrometry (UPLC-TOF-MS)--toxicological findings in cases of alleged sexual assault.

Birkler RI, Telving R, Ingemann-Hansen O, Charles AV, Johannsen M, Andreasen MF.

Forensic Sci Int. 2012 Oct 10;222(1-3):154-61. doi: 10.1016/j.forsciint.2012.05.019. Epub 2012 Jul 6.


Heterogeneous firing behavior during ictal-like epileptiform activity in vitro.

Andreasen M, Nedergaard S.

J Neurophysiol. 2012 Mar;107(5):1379-92. doi: 10.1152/jn.00309.2011. Epub 2011 Dec 7.


Farm-specific lineages of methicillin-resistant Staphylococcus aureus clonal complex 398 in Danish pig farms.

Espinosa-Gongora C, Larsen J, Moodley A, Nielsen JP, Skov RL, Andreasen M, Guardabassi L.

Epidemiol Infect. 2012 Oct;140(10):1794-9. doi: 10.1017/S0950268811002391. Epub 2011 Nov 25.


Modulation of fibrillation of hIAPP core fragments by chemical modification of the peptide backbone.

Andreasen M, Nielsen SB, Mittag T, Bjerring M, Nielsen JT, Zhang S, Nielsen EH, Jeppesen M, Christiansen G, Besenbacher F, Dong M, Nielsen NC, Skrydstrup T, Otzen DE.

Biochim Biophys Acta. 2012 Feb;1824(2):274-85. doi: 10.1016/j.bbapap.2011.10.014. Epub 2011 Oct 29.


Aβ1-16 can aggregate and induce the production of reactive oxygen species, nitric oxide, and inflammatory cytokines.

Du XT, Wang L, Wang YJ, Andreasen M, Zhan DW, Feng Y, Li M, Zhao M, Otzen D, Xue D, Yang Y, Liu RT.

J Alzheimers Dis. 2011;27(2):401-13. doi: 10.3233/JAD-2011-110476.


[Very little risk of infection in pig farms].

Andreasen M, Dahl J.

Ugeskr Laeger. 2011 Feb 14;173(7):523. Danish. No abstract available.


Baclofen and adenosine inhibition of synaptic transmission at CA3-CA1 synapses display differential sensitivity to K+ channel blockade.

Skov J, Andreasen M, Hablitz JJ, Nedergaard S.

Cell Mol Neurobiol. 2011 May;31(4):587-96. doi: 10.1007/s10571-011-9652-y. Epub 2011 Jan 28.


Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp.

Runager K, Basaiawmoit RV, Deva T, Andreasen M, Valnickova Z, Sørensen CS, Karring H, Thøgersen IB, Christiansen G, Underhaug J, Kristensen T, Nielsen NC, Klintworth GK, Otzen DE, Enghild JJ.

J Biol Chem. 2011 Feb 18;286(7):4951-8. doi: 10.1074/jbc.M110.181099. Epub 2010 Dec 6.


Weak habitat specificity in ectomycorrhizal communities associated with Salix herbacea and Salix polaris in alpine tundra.

Ryberg M, Andreasen M, Björk RG.

Mycorrhiza. 2011 May;21(4):289-96. doi: 10.1007/s00572-010-0335-1. Epub 2010 Aug 3.


A UPLC-MS/MS application for profiling of intermediary energy metabolites in microdialysis samples--a method for high-throughput.

Birkler RI, Støttrup NB, Hermannson S, Nielsen TT, Gregersen N, Bøtker HE, Andreasen MF, Johannsen M.

J Pharm Biomed Anal. 2010 Dec 1;53(4):983-90. doi: 10.1016/j.jpba.2010.06.005. Epub 2010 Jun 18.


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