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IMP/GTP balance modulates cytoophidium assembly and IMPDH activity.

Keppeke GD, Chang CC, Peng M, Chen LY, Lin WC, Pai LM, Andrade LEC, Sung LY, Liu JL.

Cell Div. 2018 Jun 15;13:5. doi: 10.1186/s13008-018-0038-0. eCollection 2018.


International consensus on antinuclear antibody patterns: definition of the AC-29 pattern associated with antibodies to DNA topoisomerase I.

Andrade LEC, Klotz W, Herold M, Conrad K, Rönnelid J, Fritzler MJ, von Mühlen CA, Satoh M, Damoiseaux J, Cruvinel WM, Chan EKL; Executive Committee of ICAP.

Clin Chem Lab Med. 2018 May 29. pii: /j/cclm.ahead-of-print/cclm-2018-0188/cclm-2018-0188.xml. doi: 10.1515/cclm-2018-0188. [Epub ahead of print]


Clarification Needed Regarding Anti-Topoisomerase I as a Biomarker for Non-Small Cell Lung Cancer.

Chan EKL, Andrade LEC.

Ann Thorac Surg. 2018 Apr 18. pii: S0003-4975(18)30530-7. doi: 10.1016/j.athoracsur.2018.03.037. [Epub ahead of print] No abstract available.


Unending story of the indirect immunofluorescence assay on HEp-2 cells: old problems and new solutions?

Meroni PL, Chan EK, Damoiseaux J, Andrade LEC, Bossuyt X, Conrad K, Mariette X, Sheldon J, Rönnelid J, Fritzler MJ; members of the committees.

Ann Rheum Dis. 2018 Apr 17. pii: annrheumdis-2018-213440. doi: 10.1136/annrheumdis-2018-213440. [Epub ahead of print] No abstract available.


International Consensus on Antinuclear Antibody Patterns: defining negative results and reporting unidentified patterns.

Herold M, Klotz W, Andrade LEC, Conrad K, Cruvinel WM, Damoiseaux J, Fritzler MJ, von Muhlen CA, Satoh M, Chan EKL.

Clin Chem Lab Med. 2018 Apr 10. pii: /j/cclm.ahead-of-print/cclm-2018-0052/cclm-2018-0052.xml. doi: 10.1515/cclm-2018-0052. [Epub ahead of print] No abstract available.


Reference standards for the detection of anti-mitochondrial and anti-rods/rings autoantibodies.

Calise SJ, Zheng B, Hasegawa T, Satoh M, Isailovic N, Ceribelli A, Andrade LEC, Boylan K, Cavazzana I, Fritzler MJ, de la Torre IG, Hiepe F, Kohl K, Selmi C, Shoenfeld Y, Tincani A, Chan EKL; IUIS Autoantibody Standardization Committee.

Clin Chem Lab Med. 2018 Feb 26. pii: /j/cclm.ahead-of-print/cclm-2017-1152/cclm-2017-1152.xml. doi: 10.1515/cclm-2017-1152. [Epub ahead of print]


[Patient safety culture in three Brazilian hospitals with different types of management].

Andrade LEL, Lopes JM, Souza MCM Filho, Vieira RF Júnior, Farias LPC, Santos CCMD, Gama ZADS.

Cien Saude Colet. 2018 Jan;23(1):161-172. doi: 10.1590/1413-81232018231.24392015. Portuguese.


Latent Class Analysis of Noninvasive Methods and Liver Biopsy in Chronic Hepatitis C: An Approach without a Gold Standard.

Fernandes FF, Perazzo H, Andrade LE, Dellavance A, Terra C, Pereira G, Pereira JL, Campos F, Ferraz ML, Perez RM.

Biomed Res Int. 2017;2017:8252980. doi: 10.1155/2017/8252980. Epub 2017 Sep 13.


Soluble CD40L is associated with increased oxidative burst and neutrophil extracellular trap release in Behçet's disease.

Perazzio SF, Soeiro-Pereira PV, Dos Santos VC, de Brito MV, Salu B, Oliva MLV, Stevens AM, de Souza AWS, Ochs HD, Torgerson TR, Condino-Neto A, Andrade LEC.

Arthritis Res Ther. 2017 Oct 19;19(1):235. doi: 10.1186/s13075-017-1443-5.


Improvement of nailfold capillary microangiopathy after immunosuppressant therapy in a child with clinically amyopathic juvenile dermatomyositis.

Campos LMA, Sallum AME, Camargo CZ, Andrade LEC, Kayser C.

Rev Bras Reumatol Engl Ed. 2017 Sep - Oct;57(5):487-490. doi: 10.1016/j.rbre.2016.05.002. Epub 2016 Jun 4. English, Portuguese. No abstract available.


Adaptation and validation of the Hospital Survey on Patient Safety Culture in an electronic Brazilian version.

Andrade LEL, Melo LOM, Silva IGD, Souza RM, Lima ALB, Freitas MR, Batista AM, Gama ZADS.

Epidemiol Serv Saude. 2017 Jul-Sep;26(3):455-468. doi: 10.5123/S1679-49742017000300004. Portuguese, English.


CD4+ T helper cells and regulatory T cells in active lupus nephritis: an imbalance towards a predominant Th1 response?

Mesquita D Jr, Kirsztajn GM, Franco MF, Reis LA, Perazzio SF, Mesquita FV, Ferreira VDS, Andrade LEC, de Souza AWS.

Clin Exp Immunol. 2018 Jan;191(1):50-59. doi: 10.1111/cei.13050. Epub 2017 Oct 10.


Hypogammaglobulinemia in children: a warning sign to look deeply?

de Melo KM, de Moraes-Pinto MI, Andrade LEC, Salomão R, Brunialti MKC, Ferreira VS, Costa-Carvalho BT.

APMIS. 2017 Oct;125(10):902-909. doi: 10.1111/apm.12738.


Foundations, facts, photos and Facebook.

Assis MR, Rocha FAC, Andrade LEC, Levy RA, Seda H.

Rev Bras Reumatol Engl Ed. 2017;57 Suppl 2:414-420. doi: 10.1016/j.rbre.2017.07.005. Epub 2017 Aug 10. English, Portuguese. No abstract available.


Biological anti-TNF drugs: immunogenicity underlying treatment failure and adverse events.

Prado MS, Bendtzen K, Andrade LEC.

Expert Opin Drug Metab Toxicol. 2017 Sep;13(9):985-995. doi: 10.1080/17425255.2017.1360280. Epub 2017 Aug 14. Review.


Expansion and intensification of humoral autoimmune response in the transition from preclinical to full-blown primary biliary cholangitis.

Dellavance A, Ferraz MLG, Cançado ELR, Andrade LEC.

Hepatology. 2017 Sep;66(3):997. doi: 10.1002/hep.29260. Epub 2017 Jul 27. No abstract available.


Outcomes of 847 childhood-onset systemic lupus erythematosus patients in three age groups.

Lopes SRM, Gormezano NWS, Gomes RC, Aikawa NE, Pereira RMR, Terreri MT, Magalhães CS, Ferreira JC, Okuda EM, Sakamoto AP, Sallum AME, Appenzeller S, Ferriani VPL, Barbosa CM, Lotufo S, Jesus AA, Andrade LEC, Campos LMA, Bonfá E, Silva CA; Brazilian Childhood-onset Systemic Lupus Erythematosus Group.

Lupus. 2017 Aug;26(9):996-1001. doi: 10.1177/0961203317690616. Epub 2017 Jan 29.


25-Hydroxivitamin D Serum Concentration, Not Free and Bioavailable Vitamin D, Is Associated with Disease Activity in Systemic Lupus Erythematosus Patients.

Eloi M, Horvath DV, Ortega JC, Prado MS, Andrade LE, Szejnfeld VL, de Moura Castro CH.

PLoS One. 2017 Jan 13;12(1):e0170323. doi: 10.1371/journal.pone.0170323. eCollection 2017.


Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients.

Grecco M, Santos VC, Pereira KM, Andrade LE, Silva NP.

Rev Bras Reumatol Engl Ed. 2016 Nov - Dec;56(6):515-520. doi: 10.1016/j.rbre.2016.07.013. Epub 2016 Oct 25. English, Portuguese.


Differential capacity of therapeutic drugs to induce Rods/Rings structures in vitro and in vivo and generation of anti-Rods/Rings autoantibodies.

Keppeke GD, Prado MS, Nunes E, Perazzio SF, Rodrigues SH, Ferraz ML, Chan EK, Andrade LE.

Clin Immunol. 2016 Dec;173:149-156. doi: 10.1016/j.clim.2016.10.004. Epub 2016 Oct 13.


Absence of mycobacterial DNA in peripheral blood and artery specimens in patients with Takayasu arteritis.

Carvalho ES, de Souza AW, Leão SC, Levy-Neto M, de Oliveira RS, Drake W, de Franco MF, Saldiva PH, Gutierrez PS, Andrade LE.

Clin Rheumatol. 2017 Jan;36(1):205-208. doi: 10.1007/s10067-016-3400-0. Epub 2016 Sep 7.


Enhanced liver fibrosis (ELF) score: Analytical performance and distribution range in a large cohort of blood donors.

Dellavance A, Fernandes F, Shimabokuro N, Latini F, Baldo D, Barreto JA, Marvulle V, Andrade LE, Ferraz ML.

Clin Chim Acta. 2016 Oct 1;461:151-5. doi: 10.1016/j.cca.2016.08.006. Epub 2016 Aug 9.


The Clinical Relevance of Anti-DFS70 Autoantibodies.

Conrad K, Röber N, Andrade LE, Mahler M.

Clin Rev Allergy Immunol. 2017 Apr;52(2):202-216. doi: 10.1007/s12016-016-8564-5. Review.


High frequency of immunodeficiency-like states in systemic lupus erythematosus: a cross-sectional study in 300 consecutive patients.

Perazzio SF, Granados Á, Salomão R, Silva NP, Carneiro-Sampaio M, Andrade LE.

Rheumatology (Oxford). 2016 Sep;55(9):1647-55. doi: 10.1093/rheumatology/kew227. Epub 2016 Jun 5.


Mild and moderate Mannose Binding Lectin deficiency are associated with systemic lupus erythematosus and lupus nephritis in Brazilian patients.

Perazzio SF, Silva NP, Carneiro-Sampaio M, Andrade LE.

Rev Bras Reumatol Engl Ed. 2016 May-Jun;56(3):220-7. doi: 10.1016/j.rbre.2016.01.002. Epub 2016 Mar 21. English, Portuguese.


Primary immunodeficiency association with systemic lupus erythematosus: review of literature and lessons learned by the Rheumatology Division of a tertiary university hospital at São Paulo, Brazil.

Errante PR, Perazzio SF, Frazão JB, da Silva NP, Andrade LE.

Rev Bras Reumatol Engl Ed. 2016 Jan-Feb;56(1):58-68. doi: 10.1016/j.rbre.2015.07.006. Epub 2015 Sep 1. English, Portuguese.


Th17 cells and CD4(+) multifunctional T cells in patients with systemic lupus erythematosus.

Araújo JA, Mesquita D Jr, de Melo Cruvinel W, Salmazi KI, Kallás EG, Andrade LE.

Rev Bras Reumatol Engl Ed. 2016 Jan-Feb;56(1):28-36. doi: 10.1016/j.rbre.2015.10.003. Epub 2015 Nov 19. English, Portuguese.


Report on the second International Consensus on ANA Pattern (ICAP) workshop in Dresden 2015.

Chan EK, Damoiseaux J, de Melo Cruvinel W, Carballo OG, Conrad K, Francescantonio PL, Fritzler MJ, Garcia-De La Torre I, Herold M, Mimori T, Satoh M, von Mühlen CA, Andrade LE.

Lupus. 2016 Jul;25(8):797-804. doi: 10.1177/0961203316640920.


From autoantibody research to standardized diagnostic assays in the management of human diseases - report of the 12th Dresden Symposium on Autoantibodies.

Conrad K, Andrade LE, Chan EK, Mahler M, Meroni PL, Pruijn GJ, Steiner G, Shoenfeld Y.

Lupus. 2016 Jul;25(8):787-96. doi: 10.1177/0961203316644337. Review.


Follicular helper T cell in immunity and autoimmunity.

Mesquita D Jr, Cruvinel WM, Resende LS, Mesquita FV, Silva NP, Câmara NO, Andrade LE.

Braz J Med Biol Res. 2016;49(5):e5209. doi: 10.1590/1414-431X20165209. Epub 2016 Apr 19. Review.


Fc gamma receptor IIIb polymorphism and systemic lupus erythematosus: association with disease susceptibility and identification of a novel FCGR3B*01 variant.

Santos VC, Grecco M, Pereira KM, Terzian CC, Andrade LE, Silva NP.

Lupus. 2016 Oct;25(11):1237-43. doi: 10.1177/0961203316636952. Epub 2016 Mar 4.


Immunogenicity of pneumococcal polysaccharide vaccine in adult systemic lupus erythematosus patients undergoing immunosuppressive treatment.

Rezende RP, Ribeiro FM, Albuquerque EM, Gayer CR, Andrade LE, Klumb EM.

Lupus. 2016 Oct;25(11):1254-9. doi: 10.1177/0961203316636472. Epub 2016 Feb 27.


Anti-rods/rings autoantibody generation in hepatitis C patients during interferon-α/ribavirin therapy.

Keppeke GD, Calise SJ, Chan EK, Andrade LE.

World J Gastroenterol. 2016 Feb 14;22(6):1966-74. doi: 10.3748/wjg.v22.i6.1966. Review.


International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results.

Damoiseaux J, von Mühlen CA, Garcia-De La Torre I, Carballo OG, de Melo Cruvinel W, Francescantonio PL, Fritzler MJ, Herold M, Mimori T, Satoh M, Andrade LE, Chan EK, Conrad K.

Auto Immun Highlights. 2016 Dec;7(1):1. doi: 10.1007/s13317-016-0075-0. Epub 2016 Jan 30.


Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.

Pereira KM, Faria AG, Liphaus BL, Jesus AA, Silva CA, Carneiro-Sampaio M, Andrade LE.

Rheumatology (Oxford). 2016 May;55(5):869-73. doi: 10.1093/rheumatology/kev436. Epub 2016 Jan 22.


Towards a better understanding of the clinical association of anti-DFS70 autoantibodies.

Mahler M, Meroni PL, Andrade LE, Khamashta M, Bizzaro N, Casiano CA, Fritzler MJ.

Autoimmun Rev. 2016 Feb;15(2):198-201. doi: 10.1016/j.autrev.2015.11.006. Epub 2015 Nov 14. Review.


The effects of freeze/thawing on the function and phenotype of CD4(+) lymphocyte subsets in normal individuals and patients with systemic lupus erythematosus.

Ferreira Vda S, Mesquita FV, Mesquita DJ, Andrade LE.

Cryobiology. 2015 Dec;71(3):507-10. doi: 10.1016/j.cryobiol.2015.10.149. Epub 2015 Oct 26.


Abnormal phenotypic distribution of regulatory and effector T cells in octogenarian and nonagenarian women.

Cruvinel Wde M, Mesquita Júnior D, Araújo JA, Samazi KC, Kállas EG, Cendoroglo MS, Andrade LE.

Rev Assoc Med Bras (1992). 2015 Aug;61(4):329-35. doi: 10.1590/1806-9282.61.04.329.


Behçet's disease heterogeneity: cytokine production and oxidative burst of phagocytes are altered in patients with severe manifestations.

Perazzio SF, Soeiro-Pereira PV, de Souza AW, Condino-Neto A, Andrade LE.

Clin Exp Rheumatol. 2015 Nov-Dec;33(6 Suppl 94):S85-95. Epub 2015 Sep 22.


Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014-2015.

Chan EK, Damoiseaux J, Carballo OG, Conrad K, de Melo Cruvinel W, Francescantonio PL, Fritzler MJ, Garcia-De La Torre I, Herold M, Mimori T, Satoh M, von Mühlen CA, Andrade LE.

Front Immunol. 2015 Aug 20;6:412. doi: 10.3389/fimmu.2015.00412. eCollection 2015. Review.


Specificity of antinuclear autoantibodies recognizing the dense fine speckled nuclear pattern: Preferential targeting of DFS70/LEDGFp75 over its interacting partner MeCP2.

Basu A, Woods-Burnham L, Ortiz G, Rios-Colon L, Figueroa J, Albesa R, Andrade LE, Mahler M, Casiano CA.

Clin Immunol. 2015 Dec;161(2):241-50. doi: 10.1016/j.clim.2015.07.014. Epub 2015 Jul 31.


High mobility group box 1 serum levels are increased in Behçet's disease, but not associated with disease activity or disease manifestations.

de Souza AW, Perazzio SF, de França NR, Andrade LE, Bijl M, Westra J, Kallenberg CG.

Rheumatology (Oxford). 2015 Dec;54(12):2151-5. doi: 10.1093/rheumatology/kev202. Epub 2015 Jul 12.


Assembly of IMPDH2-based, CTPS-based, and mixed rod/ring structures is dependent on cell type and conditions of induction.

Keppeke GD, Calise SJ, Chan EK, Andrade LE.

J Genet Genomics. 2015 Jun 20;42(6):287-99. doi: 10.1016/j.jgg.2015.04.002. Epub 2015 Apr 18.


The significance of autoantibodies to DFS70/LEDGFp75 in health and disease: integrating basic science with clinical understanding.

Ochs RL, Mahler M, Basu A, Rios-Colon L, Sanchez TW, Andrade LE, Fritzler MJ, Casiano CA.

Clin Exp Med. 2016 Aug;16(3):273-93. doi: 10.1007/s10238-015-0367-0. Epub 2015 Jun 19. Review.


High mobility group box 1 levels in large vessel vasculitis are not associated with disease activity but are influenced by age and statins.

de Souza AW, van der Geest KS, Brouwer E, Pinheiro FA, Oliveira AC, Sato EI, Andrade LE, Bijl M, Westra J, Kallenberg CG.

Arthritis Res Ther. 2015 Jun 12;17:158. doi: 10.1186/s13075-015-0672-8.


[Safe use of biological therapies for the treatment of rheumatoid arthritis and spondyloarthritides].

Mota LM, Cruz BA, Brenol CV, Pollak DF, Pinheiro Gda R, Laurindo IM, Pereira IA, Carvalho JF, Bertolo MB, Pinheiro Mde M, Freitas MV, Silva NA, Louzada-Júnior P, Sampaio-Barros PD, Giorgi RD, Lima RA, Andrade LE.

Rev Bras Reumatol. 2015 May-Jun;55(3):281-309. doi: 10.1016/j.rbr.2014.06.006. Epub 2014 Oct 13. Review. Portuguese.


Anti-rods/rings: a human model of drug-induced autoantibody generation.

Calise SJ, Keppeke GD, Andrade LE, Chan EK.

Front Immunol. 2015 Feb 5;6:41. doi: 10.3389/fimmu.2015.00041. eCollection 2015. Review.


Autoantibodies 2015: From diagnostic biomarkers toward prediction, prognosis and prevention.

Damoiseaux J, Andrade LE, Fritzler MJ, Shoenfeld Y.

Autoimmun Rev. 2015 Jun;14(6):555-63. doi: 10.1016/j.autrev.2015.01.017. Epub 2015 Feb 3. Review.


Characterization of cumulative joint damage patterns in patients with rheumatoid arthritis: a clinical, serological, and gene polymorphism perspective.

Alarcon RT, Fernandes Ada R, Laurindo IM, Bértolo MB, Pinheiro GC, Andrade LE.

J Rheumatol. 2015 Mar;42(3):405-12. doi: 10.3899/jrheum.131177. Epub 2015 Feb 1.


Microinjection of specific anti-IMPDH2 antibodies induces disassembly of cytoplasmic rods/rings that are primarily stationary and stable structures.

Keppeke GD, Andrade LE, Grieshaber SS, Chan EK.

Cell Biosci. 2015 Jan 5;5(1):1. doi: 10.1186/2045-3701-5-1. eCollection 2015.

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