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Items: 1 to 50 of 58

1.

Deletion 6q drives T-cell leukemia progression by ribosome modulation.

Gachet S, El-Chaar T, Avran D, Genescà E, Catez F, Quentin S, Delord M, Thérizols G, Briot D, Meunier G, Hernandez L, Pla M, Smits WK, Buijs-Gladdines JGCAM, Van Loocke W, Menschaert G, André-Schmutz I, Taghon T, Van Vlierberghe P, Meijerink JP, Baruchel A, Dombret H, Clappier E, Diaz JJ, Gazin C, de The H, Sigaux F, Soulier J.

Cancer Discov. 2018 Sep 28. pii: CD-17-0831. doi: 10.1158/2159-8290.CD-17-0831. [Epub ahead of print]

PMID:
30266814
2.

A Nontoxic Transduction Enhancer Enables Highly Efficient Lentiviral Transduction of Primary Murine T Cells and Hematopoietic Stem Cells.

Delville M, Soheili T, Bellier F, Durand A, Denis A, Lagresle-Peyrou C, Cavazzana M, Andre-Schmutz I, Six E.

Mol Ther Methods Clin Dev. 2018 Aug 8;10:341-347. doi: 10.1016/j.omtm.2018.08.002. eCollection 2018 Sep 21.

3.

An Optimized Lentiviral Vector Efficiently Corrects the Human Sickle Cell Disease Phenotype.

Weber L, Poletti V, Magrin E, Antoniani C, Martin S, Bayard C, Sadek H, Felix T, Meneghini V, Antoniou MN, El-Nemer W, Mavilio F, Cavazzana M, Andre-Schmutz I, Miccio A.

Mol Ther Methods Clin Dev. 2018 Aug 4;10:268-280. doi: 10.1016/j.omtm.2018.07.012. eCollection 2018 Sep 21.

4.

Severe combined immunodeficiency in stimulator of interferon genes (STING) V154M/wild-type mice.

Bouis D, Kirstetter P, Arbogast F, Lamon D, Delgado V, Jung S, Ebel C, Jacobs H, Knapp AM, Jeremiah N, Belot A, Martin T, Crow YJ, André-Schmutz I, Korganow AS, Rieux-Laucat F, Soulas-Sprauel P.

J Allergy Clin Immunol. 2018 May 23. pii: S0091-6749(18)30758-9. doi: 10.1016/j.jaci.2018.04.034. [Epub ahead of print]

PMID:
29800647
5.

Inherited Immunodeficiency: A New Association With Early-Onset Childhood Panniculitis.

Bader-Meunier B, Rieux-Laucat F, Touzot F, Frémond ML, André-Schmutz I, Fraitag S, Bodemer C.

Pediatrics. 2018 Apr;141(Suppl 5):S496-S500. doi: 10.1542/peds.2017-0213.

PMID:
29610179
6.

Plerixafor enables safe, rapid, efficient mobilization of hematopoietic stem cells in sickle cell disease patients after exchange transfusion.

Lagresle-Peyrou C, Lefrère F, Magrin E, Ribeil JA, Romano O, Weber L, Magnani A, Sadek H, Plantier C, Gabrion A, Ternaux B, Félix T, Couzin C, Stanislas A, Tréluyer JM, Lamhaut L, Joseph L, Delville M, Miccio A, André-Schmutz I, Cavazzana M.

Haematologica. 2018 May;103(5):778-786. doi: 10.3324/haematol.2017.184788. Epub 2018 Feb 22.

7.

Gene transfer into hematopoietic stem cells reduces HLH manifestations in a murine model of Munc13-4 deficiency.

Soheili T, Durand A, Sepulveda FE, Rivière J, Lagresle-Peyrou C, Sadek H, de Saint Basile G, Martin S, Mavilio F, Cavazzana M, André-Schmutz I.

Blood Adv. 2017 Dec 21;1(27):2781-2789. doi: 10.1182/bloodadvances.2017012088. eCollection 2017 Dec 26.

8.

Generation of adult human T-cell progenitors for immunotherapeutic applications.

Simons L, Ma K, de Chappedelaine C, Moiranghtem RD, Elkaim E, Olivré J, Susini S, Appourchaux K, Reimann C, Sadek H, Pellé O, Cagnard N, Magrin E, Lagresle-Peyrou C, Taghon T, Rausell A, Cavazzana M, André-Schmutz I.

J Allergy Clin Immunol. 2018 Apr;141(4):1491-1494.e4. doi: 10.1016/j.jaci.2017.10.034. Epub 2017 Dec 5. No abstract available.

9.

Neutropenia in Patients with Common Variable Immunodeficiency: a Rare Event Associated with Severe Outcome.

Guffroy A, Mourot-Cottet R, Gérard L, Gies V, Lagresle C, Pouliet A, Nitschké P, Hanein S, Bienvenu B, Chanet V, Donadieu J, Gardembas M, Karmochkine M, Nove-Josserand R, Martin T, Poindron V, Soulas-Sprauel P, Rieux-Laucat F, Fieschi C, Oksenhendler E, André-Schmutz I, Korganow AS; DEFI study group.

J Clin Immunol. 2017 Oct;37(7):715-726. doi: 10.1007/s10875-017-0434-2. Epub 2017 Aug 26.

PMID:
28842786
10.

B cells differentiate in human thymus and express AIRE.

Gies V, Guffroy A, Danion F, Billaud P, Keime C, Fauny JD, Susini S, Soley A, Martin T, Pasquali JL, Gros F, André-Schmutz I, Soulas-Sprauel P, Korganow AS.

J Allergy Clin Immunol. 2017 Mar;139(3):1049-1052.e12. doi: 10.1016/j.jaci.2016.09.044. Epub 2016 Nov 15. No abstract available.

PMID:
27864026
11.

Gene-corrected human Munc13-4-deficient CD8+ T cells can efficiently restrict EBV-driven lymphoproliferation in immunodeficient mice.

Soheili T, Rivière J, Ricciardelli I, Durand A, Verhoeyen E, Derrien AC, Lagresle-Peyrou C, de Saint Basile G, Cosset FL, Amrolia P, André-Schmutz I, Cavazzana M.

Blood. 2016 Dec 15;128(24):2859-2862. Epub 2016 Oct 31. No abstract available.

12.

Gene Therapy with Hematopoietic Stem Cells: The Diseased Bone Marrow's Point of View.

Cavazzana M, Ribeil JA, Lagresle-Peyrou C, André-Schmutz I.

Stem Cells Dev. 2017 Jan 15;26(2):71-76. doi: 10.1089/scd.2016.0230. Epub 2016 Oct 16. Review.

13.

Interleukin-15-Dependent T-Cell-like Innate Intraepithelial Lymphocytes Develop in the Intestine and Transform into Lymphomas in Celiac Disease.

Ettersperger J, Montcuquet N, Malamut G, Guegan N, Lopez-Lastra S, Gayraud S, Reimann C, Vidal E, Cagnard N, Villarese P, Andre-Schmutz I, Gomes Domingues R, Godinho-Silva C, Veiga-Fernandes H, Lhermitte L, Asnafi V, Macintyre E, Cellier C, Beldjord K, Di Santo JP, Cerf-Bensussan N, Meresse B.

Immunity. 2016 Sep 20;45(3):610-625. doi: 10.1016/j.immuni.2016.07.018. Epub 2016 Sep 6.

14.

X-linked primary immunodeficiency associated with hemizygous mutations in the moesin (MSN) gene.

Lagresle-Peyrou C, Luce S, Ouchani F, Soheili TS, Sadek H, Chouteau M, Durand A, Pic I, Majewski J, Brouzes C, Lambert N, Bohineust A, Verhoeyen E, Cosset FL, Magerus-Chatinet A, Rieux-Laucat F, Gandemer V, Monnier D, Heijmans C, van Gijn M, Dalm VA, Mahlaoui N, Stephan JL, Picard C, Durandy A, Kracker S, Hivroz C, Jabado N, de Saint Basile G, Fischer A, Cavazzana M, André-Schmutz I.

J Allergy Clin Immunol. 2016 Dec;138(6):1681-1689.e8. doi: 10.1016/j.jaci.2016.04.032. Epub 2016 Jun 4.

PMID:
27405666
15.

Alterations of circulating lymphoid committed progenitor cellular metabolism after allogeneic stem cell transplantation in humans.

Glauzy S, Peffault de Latour R, André-Schmutz I, Lachuer J, Servais S, Socié G, Clave E, Toubert A.

Exp Hematol. 2016 Sep;44(9):811-816.e3. doi: 10.1016/j.exphem.2016.05.008. Epub 2016 Jun 17.

PMID:
27321893
16.

Gene Therapy for X-Linked Severe Combined Immunodeficiency: Where Do We Stand?

Cavazzana M, Six E, Lagresle-Peyrou C, André-Schmutz I, Hacein-Bey-Abina S.

Hum Gene Ther. 2016 Feb;27(2):108-16. doi: 10.1089/hum.2015.137. Review.

17.

AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages.

Six E, Lagresle-Peyrou C, Susini S, De Chappedelaine C, Sigrist N, Sadek H, Chouteau M, Cagnard N, Fontenay M, Hermine O, Chomienne C, Reynier P, Fischer A, André-Schmutz I, Gueguen N, Cavazzana M.

Cell Death Dis. 2015 Aug 13;6:e1856. doi: 10.1038/cddis.2015.211.

18.

An in vivo genetic reversion highlights the crucial role of Myb-Like, SWIRM, and MPN domains 1 (MYSM1) in human hematopoiesis and lymphocyte differentiation.

Le Guen T, Touzot F, André-Schmutz I, Lagresle-Peyrou C, France B, Kermasson L, Lambert N, Picard C, Nitschke P, Carpentier W, Bole-Feysot C, Lim A, Cavazzana M, Callebaut I, Soulier J, Jabado N, Fischer A, de Villartay JP, Revy P.

J Allergy Clin Immunol. 2015 Dec;136(6):1619-1626.e5. doi: 10.1016/j.jaci.2015.06.008. Epub 2015 Jul 26.

PMID:
26220525
19.

Fetal consequences of maternal antiretroviral nucleoside reverse transcriptase inhibitor use in human and nonhuman primate pregnancy.

Poirier MC, Gibbons AT, Rugeles MT, Andre-Schmutz I, Blanche S.

Curr Opin Pediatr. 2015 Apr;27(2):233-9. doi: 10.1097/MOP.0000000000000193. Review.

20.

Comparing genotoxic signatures in cord blood cells from neonates exposed in utero to zidovudine or tenofovir.

Vivanti A, Soheili TS, Cuccuini W, Luce S, Mandelbrot L, Lechenadec J, Cordier AG, Azria E, Soulier J, Cavazzana M, Blanche S, André-Schmutz I.

AIDS. 2015 Jul 17;29(11):1319-24. doi: 10.1097/QAD.0000000000000564.

21.

RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement.

Cieslak A, Le Noir S, Trinquand A, Lhermitte L, Franchini DM, Villarese P, Gon S, Bond J, Simonin M, Vanhille L, Reimann C, Verhoeyen E, Larghero J, Six E, Spicuglia S, André-Schmutz I, Langerak A, Nadel B, Macintyre E, Payet-Bornet D, Asnafi V.

J Exp Med. 2014 Aug 25;211(9):1821-32. doi: 10.1084/jem.20132585. Epub 2014 Aug 18. Erratum in: J Exp Med. 2014 Dec 15;211(13):2681. Vanhile, Laurent [Corrected to Vanhille, Laurent].

22.

CXCR4-related increase of circulating human lymphoid progenitors after allogeneic hematopoietic stem cell transplantation.

Glauzy S, André-Schmutz I, Larghero J, Ezine S, Peffault de Latour R, Moins-Teisserenc H, Servais S, Robin M, Socié G, Clave E, Toubert A.

PLoS One. 2014 Mar 12;9(3):e91492. doi: 10.1371/journal.pone.0091492. eCollection 2014.

23.

The BLNK adaptor protein has a nonredundant role in human B-cell differentiation.

Lagresle-Peyrou C, Millili M, Luce S, Boned A, Sadek H, Rouiller J, Frange P, Cros G, Cavazzana M, André-Schmutz I, Schiff C.

J Allergy Clin Immunol. 2014 Jul;134(1):145-54. doi: 10.1016/j.jaci.2013.12.1083. Epub 2014 Feb 28.

PMID:
24582315
24.

Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination.

André-Schmutz I, Dal-Cortivo L, Six E, Kaltenbach S, Cocchiarella F, Le Chenadec J, Cagnard N, Cordier AG, Benachi A, Mandelbrot L, Azria E, Bouallag N, Luce S, Ternaux B, Reimann C, Revy P, Radford-Weiss I, Leschi C, Recchia A, Mavilio F, Cavazzana M, Blanche S.

J Infect Dis. 2013 Jul 15;208(2):235-43. doi: 10.1093/infdis/jit149. Epub 2013 Apr 4.

PMID:
23559464
25.

Haematopoietic stem cell transplantation for SCID patients: where do we stand?

Cavazzana-Calvo M, André-Schmutz I, Fischer A.

Br J Haematol. 2013 Jan;160(2):146-52. doi: 10.1111/bjh.12119. Epub 2012 Nov 20. Review.

PMID:
23167301
26.

Human T-lymphoid progenitors generated in a feeder-cell-free Delta-like-4 culture system promote T-cell reconstitution in NOD/SCID/γc(-/-) mice.

Reimann C, Six E, Dal-Cortivo L, Schiavo A, Appourchaux K, Lagresle-Peyrou C, de Chappedelaine C, Ternaux B, Coulombel L, Beldjord K, Cavazzana-Calvo M, Andre-Schmutz I.

Stem Cells. 2012 Aug;30(8):1771-80. doi: 10.1002/stem.1145.

27.

Amniotic fluid stem cells restore the muscle cell niche in a HSA-Cre, Smn(F7/F7) mouse model.

Piccoli M, Franzin C, Bertin E, Urbani L, Blaauw B, Repele A, Taschin E, Cenedese A, Zanon GF, André-Schmutz I, Rosato A, Melki J, Cavazzana-Calvo M, Pozzobon M, De Coppi P.

Stem Cells. 2012 Aug;30(8):1675-84. doi: 10.1002/stem.1134.

28.

MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survival.

Nehme NT, Schmid JP, Debeurme F, André-Schmutz I, Lim A, Nitschke P, Rieux-Laucat F, Lutz P, Picard C, Mahlaoui N, Fischer A, de Saint Basile G.

Blood. 2012 Apr 12;119(15):3458-68. doi: 10.1182/blood-2011-09-378364. Epub 2011 Dec 14.

29.

Cytokines and culture medium have a major impact on human in vitro T-cell differentiation.

Six EM, Benjelloun F, Garrigue A, Bonhomme D, Morillon E, Rouiller J, Cacavelli L, Blondeau J, Beldjord K, Hacein-Bey-Abina S, Cavazzana-Calvo M, André-Schmutz I.

Blood Cells Mol Dis. 2011 Jun 15;47(1):72-8. doi: 10.1016/j.bcmd.2011.04.001. Epub 2011 Apr 29.

PMID:
21531153
30.

Advances in adoptive immunotherapy to accelerate T-cellular immune reconstitution after HLA-incompatible hematopoietic stem cell transplantation.

Reimann C, Dal Cortivo L, Hacein-Bey-Abina S, Fischer A, André-Schmutz I, Cavazzana-Calvo M.

Immunotherapy. 2010 Jul;2(4):481-96. doi: 10.2217/imt.10.36. Review.

PMID:
20636003
31.

Immune reconstitution after haematopoietic stem cell transplantation: obstacles and anticipated progress.

Cavazzana-Calvo M, André-Schmutz I, Dal Cortivo L, Neven B, Hacein-Bey-Abina S, Fischer A.

Curr Opin Immunol. 2009 Oct;21(5):544-8. doi: 10.1016/j.coi.2009.08.001. Epub 2009 Sep 18. Review.

PMID:
19766472
32.

Human and murine amniotic fluid c-Kit+Lin- cells display hematopoietic activity.

Ditadi A, de Coppi P, Picone O, Gautreau L, Smati R, Six E, Bonhomme D, Ezine S, Frydman R, Cavazzana-Calvo M, André-Schmutz I.

Blood. 2009 Apr 23;113(17):3953-60. doi: 10.1182/blood-2008-10-182105. Epub 2009 Feb 12. Erratum in: Blood. 2009 Sep 10;114(11):2362.

33.

Shortening the immunodeficient period after hematopoietic stem cell transplantation.

André-Schmutz I, Six E, Bonhomme D, Rouiller J, Dal Cortivo L, Fischer A, Cavazzana-Calvo M.

Immunol Res. 2009;44(1-3):54-60. doi: 10.1007/s12026-008-8080-7.

PMID:
19034396
34.

Lymphoid-affiliated genes are associated with active histone modifications in human hematopoietic stem cells.

Maës J, Maleszewska M, Guillemin C, Pflumio F, Six E, André-Schmutz I, Cavazzana-Calvo M, Charron D, Francastel C, Goodhardt M.

Blood. 2008 Oct 1;112(7):2722-9. doi: 10.1182/blood-2008-02-140806. Epub 2008 Jul 14.

35.

Mesenchymal stromal cells can be derived from bone marrow CD133+ cells: implications for therapy.

Pozzobon M, Piccoli M, Ditadi A, Bollini S, Destro R, André-Schmutz I, Masiero L, Lenzini E, Zanesco L, Petrelli L, Cavazzana-Calvo M, Gazzola MV, De Coppi P.

Stem Cells Dev. 2009 Apr;18(3):497-510. doi: 10.1089/scd.2008.0003.

PMID:
18598159
36.

HIV-1 Nef protein expression in human CD34+ progenitors impairs the differentiation of an early T/NK cell precursor.

Dorival C, Brizzi F, Lelièvre JD, Sol-Foulon N, Six E, Henry A, André-Schmutz I, Cavazzana-Calvo M, Coulombel L, Estaquier J, Schwartz O, Lévy Y.

Virology. 2008 Jul 20;377(1):207-15. doi: 10.1016/j.virol.2008.04.009.

37.

Restoration of human B-cell differentiation into NOD-SCID mice engrafted with gene-corrected CD34+ cells isolated from Artemis or RAG1-deficient patients.

Lagresle-Peyrou C, Benjelloun F, Hue C, Andre-Schmutz I, Bonhomme D, Forveille M, Beldjord K, Hacein-Bey-Abina S, De Villartay JP, Charneau P, Durandy A, Fischer A, Cavazzana-Calvo M.

Mol Ther. 2008 Feb;16(2):396-403. doi: 10.1038/sj.mt.6300353. Epub 2007 Nov 27.

38.

A human postnatal lymphoid progenitor capable of circulating and seeding the thymus.

Six EM, Bonhomme D, Monteiro M, Beldjord K, Jurkowska M, Cordier-Garcia C, Garrigue A, Dal Cortivo L, Rocha B, Fischer A, Cavazzana-Calvo M, André-Schmutz I.

J Exp Med. 2007 Dec 24;204(13):3085-93. Epub 2007 Dec 10.

39.

[Cell therapy for inherited diseases of the hematopoietic system].

Cavazzana-Calvo M, Dal-Cortivo L, André-Schmutz I, Hacein-Bey Abina S, Fischer A.

C R Biol. 2007 Jun-Jul;330(6-7):538-42. Epub 2007 May 15. Review. French.

PMID:
17631450
40.

[Human hematopoiesis: from CD34 cells to T lymphocytes].

Cavazzana-Calvo M, Six E, André-Schmutz I, Coulombel L.

Med Sci (Paris). 2007 Feb;23(2):151-9. Review. French.

41.

[Notch ligands Delta and lymphoid development niches].

Six E, André Schmutz I, Cavazzana-Calvo M.

Med Sci (Paris). 2007 Jan;23(1):21-4. French. No abstract available.

42.

HOX11L2/TLX3 is transcriptionally activated through T-cell regulatory elements downstream of BCL11B as a result of the t(5;14)(q35;q32).

Su XY, Della-Valle V, Andre-Schmutz I, Lemercier C, Radford-Weiss I, Ballerini P, Lessard M, Lafage-Pochitaloff M, Mugneret F, Berger R, Romana SP, Bernard OA, Penard-Lacronique V.

Blood. 2006 Dec 15;108(13):4198-201. Epub 2006 Aug 22.

43.

Bone marrow transplantation attenuates the myopathic phenotype of a muscular mouse model of spinal muscular atrophy.

Salah-Mohellibi N, Millet G, André-Schmutz I, Desforges B, Olaso R, Roblot N, Courageot S, Bensimon G, Cavazzana-Calvo M, Melki J.

Stem Cells. 2006 Dec;24(12):2723-32. Epub 2006 Aug 3.

44.

Dynamics of thymus-colonizing cells during human development.

Haddad R, Guimiot F, Six E, Jourquin F, Setterblad N, Kahn E, Yagello M, Schiffer C, Andre-Schmutz I, Cavazzana-Calvo M, Gluckman JC, Delezoide AL, Pflumio F, Canque B.

Immunity. 2006 Feb;24(2):217-30.

45.

Improving immune reconstitution while preventing GvHD in allogeneic stem cell transplantation.

André-Schmutz I, Dal Cortivo L, Fischer A, Cavazzana-Calvo M.

Cytotherapy. 2005;7(2):102-8. Review.

PMID:
16040389
46.

Selective allodepletion.

Cavazzana-Calvo M, André-Schmutz I.

Cytotherapy. 2005;7(2):101. No abstract available.

PMID:
16040388
47.

Severe combined immunodeficiency. A model disease for molecular immunology and therapy.

Fischer A, Le Deist F, Hacein-Bey-Abina S, André-Schmutz I, Basile Gde S, de Villartay JP, Cavazzana-Calvo M.

Immunol Rev. 2005 Feb;203:98-109. Review.

PMID:
15661024
48.

Clonal evidence for the transduction of CD34+ cells with lymphomyeloid differentiation potential and self-renewal capacity in the SCID-X1 gene therapy trial.

Schmidt M, Hacein-Bey-Abina S, Wissler M, Carlier F, Lim A, Prinz C, Glimm H, Andre-Schmutz I, Hue C, Garrigue A, Le Deist F, Lagresle C, Fischer A, Cavazzana-Calvo M, von Kalle C.

Blood. 2005 Apr 1;105(7):2699-706. Epub 2004 Dec 7.

49.

IL-7 effect on immunological reconstitution after HSCT depends on MHC incompatibility.

André-Schmutz I, Bonhomme D, Yates F, Malassis M, Selz F, Fischer A, Cavazzana-Calvo M.

Br J Haematol. 2004 Sep;126(6):844-51.

PMID:
15352989
50.

Gene transfer for activation of CMV specific T cells.

André-Schmutz I, Dal Cortivo L, Hamel Y, Cavazzana-Calvo M.

Hum Immunol. 2004 May;65(5):565-70. Review.

PMID:
15172458

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