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A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins.

Dash TS, Shafee T, Harvey PJ, Zhang C, Peigneur S, Deuis JR, Vetter I, Tytgat J, Anderson MA, Craik DJ, Durek T, Undheim EAB.

Structure. 2018 Nov 16. pii: S0969-2126(18)30383-6. doi: 10.1016/j.str.2018.10.022. [Epub ahead of print]


Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia.

Blombery P, Anderson MA, Gong JN, Thijssen R, Birkinshaw RW, Thompson ER, Teh CE, Nguyen T, Xu Z, Flensburg C, Lew TE, Majewski IJ, Gray DHD, Westerman DA, Tam CS, Seymour JF, Czabotar PE, Huang DCS, Roberts AW.

Cancer Discov. 2018 Dec 4. pii: CD-18-1119. doi: 10.1158/2159-8290.CD-18-1119. [Epub ahead of print]


Preoperative Predictors of Choledocholithiasis in Patients Presenting with Acute Calculous Cholecystitis.

Chisholm PR, Patel AH, Law RJ, Schulman AR, Bedi AO, Kwon RS, Wamsteker EJ, Anderson MA, Elta GH, Govani SM, Prabhu A.

Gastrointest Endosc. 2018 Nov 19. pii: S0016-5107(18)33288-7. doi: 10.1016/j.gie.2018.11.017. [Epub ahead of print]


Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma.

Agarwal R, Chan YC, Tam CS, Hunter T, Vassiliadis D, Teh CE, Thijssen R, Yeh P, Wong SQ, Ftouni S, Lam EYN, Anderson MA, Pott C, Gilan O, Bell CC, Knezevic K, Blombery P, Rayeroux K, Zordan A, Li J, Huang DCS, Wall M, Seymour JF, Gray DHD, Roberts AW, Dawson MA, Dawson SJ.

Nat Med. 2019 Jan;25(1):119-129. doi: 10.1038/s41591-018-0243-z. Epub 2018 Nov 19.


Required growth facilitators propel axon regeneration across complete spinal cord injury.

Anderson MA, O'Shea TM, Burda JE, Ao Y, Barlatey SL, Bernstein AM, Kim JH, James ND, Rogers A, Kato B, Wollenberg AL, Kawaguchi R, Coppola G, Wang C, Deming TJ, He Z, Courtine G, Sofroniew MV.

Nature. 2018 Sep;561(7723):396-400. doi: 10.1038/s41586-018-0467-6. Epub 2018 Aug 29.


Nutrition and Inflammatory Biomarkers in Chronic Pancreatitis Patients.

Greer JB, Greer P, Sandhu BS, Alkaade S, Wilcox CM, Anderson MA, Sherman S, Gardner TB, Lewis MD, Guda NM, Muniraj T, Conwell D, Cote GA, Forsmark CE, Banks PA, Tang G, Stello K, Gelrud A, Brand RE, Slivka A, Whitcomb DC, Yadav D.

Nutr Clin Pract. 2018 Aug 13. doi: 10.1002/ncp.10186. [Epub ahead of print]


Resistance to the Plant Defensin NaD1 Features Modifications to the Cell Wall and Osmo-Regulation Pathways of Yeast.

McColl AI, Bleackley MR, Anderson MA, Lowe RGT.

Front Microbiol. 2018 Jul 24;9:1648. doi: 10.3389/fmicb.2018.01648. eCollection 2018.


Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases.

Jackson MA, Gilding EK, Shafee T, Harris KS, Kaas Q, Poon S, Yap K, Jia H, Guarino R, Chan LY, Durek T, Anderson MA, Craik DJ.

Nat Commun. 2018 Jun 20;9(1):2411. doi: 10.1038/s41467-018-04669-9.


Water Recovery from Advanced Water Purification Facility Reverse Osmosis Concentrate by Photobiological Treatment Followed by Secondary Reverse Osmosis.

Ikehata K, Zhao Y, Kulkarni HV, Li Y, Snyder SA, Ishida KP, Anderson MA.

Environ Sci Technol. 2018 Aug 7;52(15):8588-8595. doi: 10.1021/acs.est.8b00951. Epub 2018 Jul 9.


Recurrent Acute Pancreatitis Significantly Reduces Quality of Life Even in the Absence of Overt Chronic Pancreatitis.

Coté GA, Yadav D, Abberbock JA, Whitcomb DC, Sherman S, Sandhu BS, Anderson MA, Lewis MD, Alkaade S, Singh VK, Baillie J, Banks PA, Conwell D, Guda NM, Muniraj T, Tang G, Brand R, Gelrud A, Amann ST, Forsmark CE, Wilcox CM, Slivka A, Gardner TB.

Am J Gastroenterol. 2018 Jun;113(6):906-912. doi: 10.1038/s41395-018-0087-7. Epub 2018 Jun 5.


Known genetic susceptibility factors for chronic pancreatitis in patients of European ancestry are rare in patients of African ancestry.

Phillips AE, LaRusch J, Greer P, Abberbock J, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Brand RE, Conwell D, Coté GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis M, Money ME, Muniraj T, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Wilcox CM, Whitcomb DC, Yadav D.

Pancreatology. 2018 May 19. pii: S1424-3903(18)30588-X. doi: 10.1016/j.pan.2018.05.482. [Epub ahead of print]


Acute posterior cruciate ligament injuries: effect of location, severity, and associated injuries on surgical management.

Anderson MA, Simeone FJ, Palmer WE, Chang CY.

Skeletal Radiol. 2018 Nov;47(11):1523-1532. doi: 10.1007/s00256-018-2977-6. Epub 2018 Jun 1.


X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.

Järvå M, Lay FT, Phan TK, Humble C, Poon IKH, Bleackley MR, Anderson MA, Hulett MD, Kvansakul M.

Nat Commun. 2018 May 17;9(1):1962. doi: 10.1038/s41467-018-04434-y.


Identification of Candidate Iron Transporters From the ZIP/ZnT Gene Families in the Mosquito Aedes aegypti.

Tsujimoto H, Anderson MAE, Myles KM, Adelman ZN.

Front Physiol. 2018 Apr 12;9:380. doi: 10.3389/fphys.2018.00380. eCollection 2018.


Ibrutinib plus Venetoclax for the Treatment of Mantle-Cell Lymphoma.

Tam CS, Anderson MA, Pott C, Agarwal R, Handunnetti S, Hicks RJ, Burbury K, Turner G, Di Iulio J, Bressel M, Westerman D, Lade S, Dreyling M, Dawson SJ, Dawson MA, Seymour JF, Roberts AW.

N Engl J Med. 2018 Mar 29;378(13):1211-1223. doi: 10.1056/NEJMoa1715519.


Cortico-reticulo-spinal circuit reorganization enables functional recovery after severe spinal cord contusion.

Asboth L, Friedli L, Beauparlant J, Martinez-Gonzalez C, Anil S, Rey E, Baud L, Pidpruzhnykova G, Anderson MA, Shkorbatova P, Batti L, Pagès S, Kreider J, Schneider BL, Barraud Q, Courtine G.

Nat Neurosci. 2018 Apr;21(4):576-588. doi: 10.1038/s41593-018-0093-5. Epub 2018 Mar 19.


Deterministic Integration of Biological and Soft Materials onto 3D Microscale Cellular Frameworks.

McCracken JM, Xu S, Badea A, Jang KI, Yan Z, Wetzel DJ, Nan K, Lin Q, Han M, Anderson MA, Lee JW, Wei Z, Pharr M, Wang R, Su J, Rubakhin SS, Sweedler JV, Rogers JA, Nuzzo RG.

Adv Biosyst. 2017 Sep;1(9). pii: 1700068. doi: 10.1002/adbi.201700068. Epub 2017 Jul 31.


15(V/K) kinetic isotope effect and steady-state kinetic analysis for the transglutaminase 2 catalyzed deamidation and transamidation reactions.

Wells EA, Anderson MA, Zeczycki TN.

Arch Biochem Biophys. 2018 Apr 2;643:57-61. doi: 10.1016/ Epub 2018 Feb 23.


The evolution, function and mechanisms of action for plant defensins.

Parisi K, Shafee TMA, Quimbar P, van der Weerden NL, Bleackley MR, Anderson MA.

Semin Cell Dev Biol. 2018 Feb 22. pii: S1084-9521(17)30469-X. doi: 10.1016/j.semcdb.2018.02.004. [Epub ahead of print] Review.


Mind the gap: results of a multispecialty survey on coordination of care for peri-procedural anticoagulation.

Kurlander JE, Barnes GD, Anderson MA, Haymart B, Kline-Rogers E, Kaatz S, Saini SD, Krein SL, Richardson CR, Froehlich JB.

J Thromb Thrombolysis. 2018 Apr;45(3):403-409. doi: 10.1007/s11239-018-1625-2.


The Plant Defensin NaD1 Enters the Cytoplasm of Candida Albicans via Endocytosis.

Hayes BME, Bleackley MR, Anderson MA, van der Weerden NL.

J Fungi (Basel). 2018 Feb 6;4(1). pii: E20. doi: 10.3390/jof4010020.


Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta.

Poon S, Harris KS, Jackson MA, McCorkelle OC, Gilding EK, Durek T, van der Weerden NL, Craik DJ, Anderson MA.

J Exp Bot. 2018 Jan 23;69(3):633-641. doi: 10.1093/jxb/erx422.


The Henry's constant of monochloramine.

Garcia MA, Anderson MA.

Chemosphere. 2018 Feb;192:244-249. doi: 10.1016/j.chemosphere.2017.10.157. Epub 2017 Oct 30.


Synergistic Activity between Two Antifungal Proteins, the Plant Defensin NaD1 and the Bovine Pancreatic Trypsin Inhibitor.

Bleackley MR, Dawson CS, McKenna JA, Quimbar P, Hayes BME, van der Weerden NL, Anderson MA.

mSphere. 2017 Oct 18;2(5). pii: e00390-17. doi: 10.1128/mSphere.00390-17. eCollection 2017 Sep-Oct.


Patient and Disease Characteristics Associated With the Presence of Diabetes Mellitus in Adults With Chronic Pancreatitis in the United States.

Bellin MD, Whitcomb DC, Abberbock J, Sherman S, Sandhu BS, Gardner TB, Anderson MA, Lewis MD, Alkaade S, Singh VK, Baillie J, Banks PA, Conwell D, Cote GA, Guda NM, Muniraj T, Tang G, Brand RE, Gelrud A, Amann ST, Forsmark CE, Wilcox CM, Slivka A, Yadav D.

Am J Gastroenterol. 2017 Sep;112(9):1457-1465. doi: 10.1038/ajg.2017.181. Epub 2017 Jul 25.


Validation of Demographics, Etiology, and Risk Factors for Chronic Pancreatitis in the USA: A Report of the North American Pancreas Study (NAPS) Group.

Conwell DL, Banks PA, Sandhu BS, Sherman S, Al-Kaade S, Gardner TB, Anderson MA, Wilcox CM, Lewis MD, Muniraj T, Forsmark CE, Cote GA, Guda NM, Tian Y, Romagnuolo J, Wisniewski SR, Brand R, Gelrud A, Slivka A, Whitcomb DC, Yadav D.

Dig Dis Sci. 2017 Aug;62(8):2133-2140. doi: 10.1007/s10620-017-4621-z. Epub 2017 Jun 9.


Specialist Endoscopists Are Associated with a Decreased Risk of Incomplete Polyp Resection During Endoscopic Mucosal Resection in the Colon.

Tavakkoli A, Law RJ, Bedi AO, Prabhu A, Hiatt T, Anderson MA, Wamsteker EJ, Elmunzer BJ, Piraka CR, Scheiman JM, Elta GH, Kwon RS.

Dig Dis Sci. 2017 Sep;62(9):2464-2471. doi: 10.1007/s10620-017-4643-6. Epub 2017 Jun 9.


Clinicopathological features and outcomes of progression of CLL on the BCL2 inhibitor venetoclax.

Anderson MA, Tam C, Lew TE, Juneja S, Juneja M, Westerman D, Wall M, Lade S, Gorelik A, Huang DCS, Seymour JF, Roberts AW.

Blood. 2017 Jun 22;129(25):3362-3370. doi: 10.1182/blood-2017-01-763003. Epub 2017 May 4.


Academic Pancreas Centers of Excellence: Guidance from a multidisciplinary chronic pancreatitis working group at PancreasFest.

Sheth SG, Conwell DL, Whitcomb DC, Alsante M, Anderson MA, Barkin J, Brand R, Cote GA, Freedman SD, Gelrud A, Gorelick F, Lee LS, Morgan K, Pandol S, Singh VK, Yadav D, Wilcox CM, Hart PA.

Pancreatology. 2017 May - Jun;17(3):419-430. doi: 10.1016/j.pan.2017.02.015. Epub 2017 Feb 28.


Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities.

Machicado JD, Amann ST, Anderson MA, Abberbock J, Sherman S, Conwell DL, Cote GA, Singh VK, Lewis MD, Alkaade S, Sandhu BS, Guda NM, Muniraj T, Tang G, Baillie J, Brand RE, Gardner TB, Gelrud A, Forsmark CE, Banks PA, Slivka A, Wilcox CM, Whitcomb DC, Yadav D.

Am J Gastroenterol. 2017 Apr;112(4):633-642. doi: 10.1038/ajg.2017.42. Epub 2017 Feb 28.


Venous thromboembolism management practices and knowledge of guidelines: a survey of Australian haematologists and respiratory physicians.

Wallace R, Anderson MA, See K, Gorelik A, Irving L, Manser R.

Intern Med J. 2017 Apr;47(4):436-446. doi: 10.1111/imj.13382.


Phase I First-in-Human Study of Venetoclax in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma.

Davids MS, Roberts AW, Seymour JF, Pagel JM, Kahl BS, Wierda WG, Puvvada S, Kipps TJ, Anderson MA, Salem AH, Dunbar M, Zhu M, Peale F, Ross JA, Gressick L, Desai M, Kim SY, Verdugo M, Humerickhouse RA, Gordon GB, Gerecitano JF.

J Clin Oncol. 2017 Mar 10;35(8):826-833. doi: 10.1200/JCO.2016.70.4320. Epub 2017 Jan 17.


Venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukaemia: a phase 1b study.

Seymour JF, Ma S, Brander DM, Choi MY, Barrientos J, Davids MS, Anderson MA, Beaven AW, Rosen ST, Tam CS, Prine B, Agarwal SK, Munasinghe W, Zhu M, Lash LL, Desai M, Cerri E, Verdugo M, Kim SY, Humerickhouse RA, Gordon GB, Kipps TJ, Roberts AW.

Lancet Oncol. 2017 Feb;18(2):230-240. doi: 10.1016/S1470-2045(17)30012-8. Epub 2017 Jan 13.


Provocative endoscopy: Let sleeping dogs lie or grab the tiger by the tail?

Shuster D, Anderson MA.

Gastrointest Endosc. 2017 Jan;85(1):121-122. doi: 10.1016/j.gie.2016.08.036. No abstract available.


Concentrator photovoltaic module architectures with capabilities for capture and conversion of full global solar radiation.

Lee KT, Yao Y, He J, Fisher B, Sheng X, Lumb M, Xu L, Anderson MA, Scheiman D, Han S, Kang Y, Gumus A, Bahabry RR, Lee JW, Paik U, Bronstein ND, Alivisatos AP, Meitl M, Burroughs S, Hussain MM, Lee JC, Nuzzo RG, Rogers JA.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):E8210-E8218. doi: 10.1073/pnas.1617391113. Epub 2016 Dec 5.


Transformed Lymphoma.

Anderson MA, Blombery P, Seymour JF.

Hematol Oncol Clin North Am. 2016 Dec;30(6):1317-1332. doi: 10.1016/j.hoc.2016.07.012. Review.


Membrane-less organic-inorganic aqueous flow batteries with improved cell potential.

Leung PK, Martin T, Shah AA, Anderson MA, Palma J.

Chem Commun (Camb). 2016 Dec 6;52(99):14270-14273.


The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies.

Redin C, Brand H, Collins RL, Kammin T, Mitchell E, Hodge JC, Hanscom C, Pillalamarri V, Seabra CM, Abbott MA, Abdul-Rahman OA, Aberg E, Adley R, Alcaraz-Estrada SL, Alkuraya FS, An Y, Anderson MA, Antolik C, Anyane-Yeboa K, Atkin JF, Bartell T, Bernstein JA, Beyer E, Blumenthal I, Bongers EM, Brilstra EH, Brown CW, Brüggenwirth HT, Callewaert B, Chiang C, Corning K, Cox H, Cuppen E, Currall BB, Cushing T, David D, Deardorff MA, Dheedene A, D'Hooghe M, de Vries BB, Earl DL, Ferguson HL, Fisher H, FitzPatrick DR, Gerrol P, Giachino D, Glessner JT, Gliem T, Grady M, Graham BH, Griffis C, Gripp KW, Gropman AL, Hanson-Kahn A, Harris DJ, Hayden MA, Hill R, Hochstenbach R, Hoffman JD, Hopkin RJ, Hubshman MW, Innes AM, Irons M, Irving M, Jacobsen JC, Janssens S, Jewett T, Johnson JP, Jongmans MC, Kahler SG, Koolen DA, Korzelius J, Kroisel PM, Lacassie Y, Lawless W, Lemyre E, Leppig K, Levin AV, Li H, Li H, Liao EC, Lim C, Lose EJ, Lucente D, Macera MJ, Manavalan P, Mandrile G, Marcelis CL, Margolin L, Mason T, Masser-Frye D, McClellan MW, Mendoza CJ, Menten B, Middelkamp S, Mikami LR, Moe E, Mohammed S, Mononen T, Mortenson ME, Moya G, Nieuwint AW, Ordulu Z, Parkash S, Pauker SP, Pereira S, Perrin D, Phelan K, Aguilar RE, Poddighe PJ, Pregno G, Raskin S, Reis L, Rhead W, Rita D, Renkens I, Roelens F, Ruliera J, Rump P, Schilit SL, Shaheen R, Sparkes R, Spiegel E, Stevens B, Stone MR, Tagoe J, Thakuria JV, van Bon BW, van de Kamp J, van Der Burgt I, van Essen T, van Ravenswaaij-Arts CM, van Roosmalen MJ, Vergult S, Volker-Touw CM, Warburton DP, Waterman MJ, Wiley S, Wilson A, Yerena-de Vega MC, Zori RT, Levy B, Brunner HG, de Leeuw N, Kloosterman WP, Thorland EC, Morton CC, Gusella JF, Talkowski ME.

Nat Genet. 2017 Jan;49(1):36-45. doi: 10.1038/ng.3720. Epub 2016 Nov 14.


Breath Testing for Barrett's Esophagus Using Exhaled Volatile Organic Compound Profiling With an Electronic Nose Device.

Chan DK, Zakko L, Visrodia KH, Leggett CL, Lutzke LS, Clemens MA, Allen JD, Anderson MA, Wang KK.

Gastroenterology. 2017 Jan;152(1):24-26. doi: 10.1053/j.gastro.2016.11.001. Epub 2016 Nov 5. No abstract available.


The inner membrane protein YhiM is necessary for Escherichia coli growth at high temperatures and low osmolarity.

Anderson MA, Mann MD, Evans MA, Sparks-Thissen RL.

Arch Microbiol. 2017 Jan;199(1):171-175. doi: 10.1007/s00203-016-1288-3. Epub 2016 Sep 14.


Plant Defensins NaD1 and NaD2 Induce Different Stress Response Pathways in Fungi.

Dracatos PM, Payne J, Di Pietro A, Anderson MA, Plummer KM.

Int J Mol Sci. 2016 Sep 3;17(9). pii: E1473. doi: 10.3390/ijms17091473.


The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured.

Daly NL, Gunasekera S, Clark RJ, Lin F, Wade JD, Anderson MA, Craik DJ.

Biopolymers. 2016 Nov;106(6):825-833. doi: 10.1002/bip.22977.


Convergent evolution of defensin sequence, structure and function.

Shafee TM, Lay FT, Phan TK, Anderson MA, Hulett MD.

Cell Mol Life Sci. 2017 Feb;74(4):663-682. doi: 10.1007/s00018-016-2344-5. Epub 2016 Aug 24. Review.


Thermoresponsive Copolypeptide Hydrogel Vehicles for Central Nervous System Cell Delivery.

Zhang S, Burda JE, Anderson MA, Zhao Z, Ao Y, Cheng Y, Sun Y, Deming TJ, Sofroniew MV.

ACS Biomater Sci Eng. 2015 Aug 10;1(8):705-717. Epub 2015 Jun 22.


Racial Differences in the Clinical Profile, Causes, and Outcome of Chronic Pancreatitis.

Wilcox CM, Sandhu BS, Singh V, Gelrud A, Abberbock JN, Sherman S, Cote GA, Al-Kaade S, Anderson MA, Gardner TB, Lewis MD, Forsmark CE, Guda NM, Romagnuolo J, Baillie J, Amann ST, Muniraj T, Tang G, Conwell DL, Banks PA, Brand RE, Slivka A, Whitcomb D, Yadav D.

Am J Gastroenterol. 2016 Oct;111(10):1488-1496. doi: 10.1038/ajg.2016.316. Epub 2016 Aug 16.


Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant.

Bleackley MR, Payne JA, Hayes BM, Durek T, Craik DJ, Shafee TM, Poon IK, Hulett MD, van der Weerden NL, Anderson MA.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):6302-12. doi: 10.1128/AAC.01479-16. Print 2016 Oct.


The Defensins Consist of Two Independent, Convergent Protein Superfamilies.

Shafee TM, Lay FT, Hulett MD, Anderson MA.

Mol Biol Evol. 2016 Sep;33(9):2345-56. doi: 10.1093/molbev/msw106. Epub 2016 Jun 13.


AirJump: Using Interfaces to Instantly Perform Simultaneous Extractions.

Berry SM, Pezzi HM, LaVanway AJ, Guckenberger DJ, Anderson MA, Beebe DJ.

ACS Appl Mater Interfaces. 2016 Jun 22;8(24):15040-5. doi: 10.1021/acsami.6b02555. Epub 2016 Jun 10.


New Operational Modes to Increase Energy Efficiency in Capacitive Deionization Systems.

García-Quismondo E, Santos C, Soria J, Palma J, Anderson MA.

Environ Sci Technol. 2016 Jun 7;50(11):6053-60. doi: 10.1021/acs.est.5b05379. Epub 2016 May 19.


The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism.

Anderson MA, Deng J, Seymour JF, Tam C, Kim SY, Fein J, Yu L, Brown JR, Westerman D, Si EG, Majewski IJ, Segal D, Heitner Enschede SL, Huang DC, Davids MS, Letai A, Roberts AW.

Blood. 2016 Jun 23;127(25):3215-24. doi: 10.1182/blood-2016-01-688796. Epub 2016 Apr 11.

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