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p120-catenin regulates WNT signaling and EMT in the mouse embryo.

Hernández-Martínez R, Ramkumar N, Anderson KV.

Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16872-16881. doi: 10.1073/pnas.1902843116. Epub 2019 Aug 1.


Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.

Bowie E, Norris R, Anderson KV, Goetz SC.

PLoS Genet. 2018 Dec 10;14(12):e1007844. doi: 10.1371/journal.pgen.1007844. eCollection 2018 Dec.


Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.

Bozal-Basterra L, Martín-Ruíz I, Pirone L, Liang Y, Sigurðsson JO, Gonzalez-Santamarta M, Giordano I, Gabicagogeascoa E, de Luca A, Rodríguez JA, Wilkie AOM, Kohlhase J, Eastwood D, Yale C, Olsen JV, Rauchman M, Anderson KV, Sutherland JD, Barrio R.

Am J Hum Genet. 2018 Feb 1;102(2):249-265. doi: 10.1016/j.ajhg.2017.12.017.


ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2.

Jain D, Puno MR, Meydan C, Lailler N, Mason CE, Lima CD, Anderson KV, Keeney S.

Elife. 2018 Jan 23;7. pii: e30919. doi: 10.7554/eLife.30919.


STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo.

Bazzi H, Soroka E, Alcorn HL, Anderson KV.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10928-E10936. doi: 10.1073/pnas.1713535114. Epub 2017 Dec 4.


The small GTPase RSG1 controls a final step in primary cilia initiation.

Agbu SO, Liang Y, Liu A, Anderson KV.

J Cell Biol. 2018 Jan 2;217(1):413-427. doi: 10.1083/jcb.201604048. Epub 2017 Oct 16.


rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline.

Jain D, Meydan C, Lange J, Claeys Bouuaert C, Lailler N, Mason CE, Anderson KV, Keeney S.

PLoS Genet. 2017 Aug 30;13(8):e1006964. doi: 10.1371/journal.pgen.1006964. eCollection 2017 Aug.


The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling.

Goetz SC, Bangs F, Barrington CL, Katsanis N, Anderson KV.

PLoS One. 2017 Mar 14;12(3):e0173399. doi: 10.1371/journal.pone.0173399. eCollection 2017.


Primary Cilia and Mammalian Hedgehog Signaling.

Bangs F, Anderson KV.

Cold Spring Harb Perspect Biol. 2017 May 1;9(5). pii: a028175. doi: 10.1101/cshperspect.a028175. Review.


Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation.

Ramkumar N, Omelchenko T, Silva-Gagliardi NF, McGlade CJ, Wijnholds J, Anderson KV.

Nat Cell Biol. 2016 Dec;18(12):1281-1291. doi: 10.1038/ncb3442. Epub 2016 Nov 21.


Microtubule Motors Drive Hedgehog Signaling in Primary Cilia.

He M, Agbu S, Anderson KV.

Trends Cell Biol. 2017 Feb;27(2):110-125. doi: 10.1016/j.tcb.2016.09.010. Epub 2016 Oct 17. Review.


Patient satisfaction with extended-interval warfarin monitoring.

Carris NW, Hwang AY, Smith SM, Taylor JR, Sando K, Powell J, Rosenberg EI, Zumberg MS, Gums JG, Dietrich EA, Anderson KV.

J Thromb Thrombolysis. 2016 Nov;42(4):486-93. doi: 10.1007/s11239-016-1385-9.


Somatic PIK3CA mutations as a driver of sporadic venous malformations.

Castel P, Carmona FJ, Grego-Bessa J, Berger MF, Viale A, Anderson KV, Bague S, Scaltriti M, Antonescu CR, Baselga E, Baselga J.

Sci Transl Med. 2016 Mar 30;8(332):332ra42. doi: 10.1126/scitranslmed.aaf1164.


The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium.

Grego-Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson KV.

Elife. 2016 Jan 26;5:e12034. doi: 10.7554/eLife.12034.


Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2.

Ramkumar N, Harvey BM, Lee JD, Alcorn HL, Silva-Gagliardi NF, McGlade CJ, Bestor TH, Wijnholds J, Haltiwanger RS, Anderson KV.

PLoS Genet. 2015 Oct 23;11(10):e1005551. doi: 10.1371/journal.pgen.1005551. eCollection 2015 Oct.


Feasibility of Extended-interval Follow-up for Patients Receiving Warfarin.

Carris NW, Spinelli A, Pierini D, Taylor JR, Anderson KV, Sando K, Powell J, Rosenberg EI, Zumberg MS, Smith SM, Gums JG, Dietrich E.

Cardiovasc Ther. 2015 Jun;33(3):98-103. doi: 10.1111/1755-5922.12115.


Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains.

Grego-Bessa J, Hildebrand J, Anderson KV.

Development. 2015 Apr 1;142(7):1305-14. doi: 10.1242/dev.115493. Epub 2015 Mar 5.


Lineage specificity of primary cilia in the mouse embryo.

Bangs FK, Schrode N, Hadjantonakis AK, Anderson KV.

Nat Cell Biol. 2015 Feb;17(2):113-22. doi: 10.1038/ncb3091. Epub 2015 Jan 19.


β-Pix directs collective migration of anterior visceral endoderm cells in the early mouse embryo.

Omelchenko T, Rabadan MA, Hernández-Martínez R, Grego-Bessa J, Anderson KV, Hall A.

Genes Dev. 2014 Dec 15;28(24):2764-77. doi: 10.1101/gad.251371.114.


Centrioles in the mouse: cilia and beyond.

Bazzi H, Anderson KV.

Cell Cycle. 2014;13(18):2809. doi: 10.4161/15384101.2014.954450. No abstract available.


ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling.

Handschuh K, Feenstra J, Koss M, Ferretti E, Risolino M, Zewdu R, Sahai MA, Bénazet JD, Peng XP, Depew MJ, Quintana L, Sharpe J, Wang B, Alcorn H, Rivi R, Butcher S, Manak JR, Vaccari T, Weinstein H, Anderson KV, Lacy E, Selleri L.

Cell Rep. 2014 Oct 23;9(2):674-87. doi: 10.1016/j.celrep.2014.09.019. Epub 2014 Oct 16.


Cortical neurogenesis in the absence of centrioles.

Insolera R, Bazzi H, Shao W, Anderson KV, Shi SH.

Nat Neurosci. 2014 Nov;17(11):1528-35. doi: 10.1038/nn.3831. Epub 2014 Oct 5.


The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment.

He M, Subramanian R, Bangs F, Omelchenko T, Liem KF Jr, Kapoor TM, Anderson KV.

Nat Cell Biol. 2014 Jul;16(7):663-72. doi: 10.1038/ncb2988. Epub 2014 Jun 22.


Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo.

Bazzi H, Anderson KV.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1491-500. doi: 10.1073/pnas.1400568111. Epub 2014 Mar 31.


Azilsartan medoxomil/chlorthalidone: a new fixed-dose combination antihypertensive.

Pierini D, Anderson KV.

Ann Pharmacother. 2013 May;47(5):694-703. doi: 10.1345/aph.1R618. Epub 2013 Apr 12.


Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo.

Mahaffey JP, Grego-Bessa J, Liem KF Jr, Anderson KV.

Development. 2013 Mar;140(6):1262-71. doi: 10.1242/dev.085316. Epub 2013 Feb 13.


The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.

Goetz SC, Liem KF Jr, Anderson KV.

Cell. 2012 Nov 9;151(4):847-858. doi: 10.1016/j.cell.2012.10.010.


The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.

Liem KF Jr, Ashe A, He M, Satir P, Moran J, Beier D, Wicking C, Anderson KV.

J Cell Biol. 2012 Jun 11;197(6):789-800. doi: 10.1083/jcb.201110049.


Pten regulates collective cell migration during specification of the anterior-posterior axis of the mouse embryo.

Bloomekatz J, Grego-Bessa J, Migeotte I, Anderson KV.

Dev Biol. 2012 Apr 15;364(2):192-201. doi: 10.1016/j.ydbio.2012.02.005. Epub 2012 Feb 11.


Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies.

Ashe A, Butterfield NC, Town L, Courtney AD, Cooper AN, Ferguson C, Barry R, Olsson F, Liem KF Jr, Parton RG, Wainwright BJ, Anderson KV, Whitelaw E, Wicking C.

Hum Mol Genet. 2012 Apr 15;21(8):1808-23. doi: 10.1093/hmg/ddr613. Epub 2012 Jan 6.


Ror2 enhances polarity and directional migration of primordial germ cells.

Laird DJ, Altshuler-Keylin S, Kissner MD, Zhou X, Anderson KV.

PLoS Genet. 2011 Dec;7(12):e1002428. doi: 10.1371/journal.pgen.1002428. Epub 2011 Dec 22.


Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.

Tuson M, He M, Anderson KV.

Development. 2011 Nov;138(22):4921-30. doi: 10.1242/dev.070805. Epub 2011 Oct 17.


SnapShot: mouse primitive streak.

Ramkumar N, Anderson KV.

Cell. 2011 Aug 5;146(3):488-488.e2. doi: 10.1016/j.cell.2011.07.028. No abstract available.


Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo.

Migeotte I, Grego-Bessa J, Anderson KV.

Development. 2011 Jul;138(14):3011-20. doi: 10.1242/dev.059766.


A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus.

Friedland-Little JM, Hoffmann AD, Ocbina PJ, Peterson MA, Bosman JD, Chen Y, Cheng SY, Anderson KV, Moskowitz IP.

Hum Mol Genet. 2011 Oct 1;20(19):3725-37. doi: 10.1093/hmg/ddr241. Epub 2011 Jun 8.


New options in anticoagulation for the prevention of venous thromboembolism and stroke.

Clayville LR, Anderson KV, Miller SA, St Onge EL.

P T. 2011 Feb;36(2):86-99. No abstract available.


Tissue-specific roles of Axin2 in the inhibition and activation of Wnt signaling in the mouse embryo.

Qian L, Mahaffey JP, Alcorn HL, Anderson KV.

Proc Natl Acad Sci U S A. 2011 May 24;108(21):8692-7. doi: 10.1073/pnas.1100328108. Epub 2011 May 9. Erratum in: Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11297.


Complex interactions between genes controlling trafficking in primary cilia.

Ocbina PJ, Eggenschwiler JT, Moskowitz I, Anderson KV.

Nat Genet. 2011 Jun;43(6):547-53. doi: 10.1038/ng.832. Epub 2011 May 8.


Essential role for Abi1 in embryonic survival and WAVE2 complex integrity.

Dubielecka PM, Ladwein KI, Xiong X, Migeotte I, Chorzalska A, Anderson KV, Sawicki JA, Rottner K, Stradal TE, Kotula L.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7022-7. doi: 10.1073/pnas.1016811108. Epub 2011 Apr 11.


The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation.

Becker-Heck A, Zohn IE, Okabe N, Pollock A, Lenhart KB, Sullivan-Brown J, McSheene J, Loges NT, Olbrich H, Haeffner K, Fliegauf M, Horvath J, Reinhardt R, Nielsen KG, Marthin JK, Baktai G, Anderson KV, Geisler R, Niswander L, Omran H, Burdine RD.

Nat Genet. 2011 Jan;43(1):79-84. doi: 10.1038/ng.727. Epub 2010 Dec 5.


Global control of motor neuron topography mediated by the repressive actions of a single hox gene.

Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS.

Neuron. 2010 Sep 9;67(5):781-96. doi: 10.1016/j.neuron.2010.08.008.


Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse.

Migeotte I, Omelchenko T, Hall A, Anderson KV.

PLoS Biol. 2010 Aug 3;8(8):e1000442. doi: 10.1371/journal.pbio.1000442.


Left-right patterning in the mouse requires Epb4.1l5-dependent morphogenesis of the node and midline.

Lee JD, Migeotte I, Anderson KV.

Dev Biol. 2010 Oct 15;346(2):237-46. doi: 10.1016/j.ydbio.2010.07.029. Epub 2010 Aug 1.


Development of head organizer of the mouse embryo depends on a high level of mitochondrial metabolism.

Zhou X, Anderson KV.

Dev Biol. 2010 Aug 1;344(1):185-95. doi: 10.1016/j.ydbio.2010.04.031. Epub 2010 May 4.


The primary cilium: a signalling centre during vertebrate development.

Goetz SC, Anderson KV.

Nat Rev Genet. 2010 May;11(5):331-44. doi: 10.1038/nrg2774. Review.


Drosophila Rel proteins are central regulators of a robust, multi-organ immune network.

Matova N, Anderson KV.

J Cell Sci. 2010 Feb 15;123(Pt 4):627-33. doi: 10.1242/jcs.060731.


A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling.

Weatherbee SD, Niswander LA, Anderson KV.

Hum Mol Genet. 2009 Dec 1;18(23):4565-75. doi: 10.1093/hmg/ddp422. Epub 2009 Sep 22.


Primary cilia are not required for normal canonical Wnt signaling in the mouse embryo.

Ocbina PJ, Tuson M, Anderson KV.

PLoS One. 2009 Aug 31;4(8):e6839. doi: 10.1371/journal.pone.0006839.


Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.

Liem KF Jr, He M, Ocbina PJ, Anderson KV.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13377-82. doi: 10.1073/pnas.0906944106. Epub 2009 Jul 29.


The primary cilium as a Hedgehog signal transduction machine.

Goetz SC, Ocbina PJ, Anderson KV.

Methods Cell Biol. 2009;94:199-222. doi: 10.1016/S0091-679X(08)94010-3. Epub 2009 Dec 23.

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