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Does an Uninstrumented Level Increase the Rate of Revision Surgery in a Multilevel Posterior Cervical Decompression and Fusion?

Schroeder GD, McKenzie JC, Casper DS, Mangan JJ, Stull J, Kepler CK, Nicholson KJ, Kurd MF, Hilibrand AS, Murphy H, Woods BI, Radcliff KE, Anderson DG, Vaccaro AR, Rihn JA.

Clin Spine Surg. 2019 Dec;32(10):E416-E419. doi: 10.1097/BSD.0000000000000910.


How Does BMI Influence Outcomes in Patients after Lumbar Fusion?

Divi SN, Goyal DKC, Galetta MS, Fang T, Padua FG, Reyes AA, Kaye ID, Kurd MF, Woods BI, Radcliff KE, Rihn JA, Anderson DG, Hilibrand AS, Kepler CK, Vaccaro AR, Schroeder GD.

Spine (Phila Pa 1976). 2019 Nov 15. doi: 10.1097/BRS.0000000000003313. [Epub ahead of print]


Circulating miR-155-5p as a Novel Biomarker of Lumbar Degenerative Disc Disease.

Divi SN, Markova DZ, Fang T, Guzek R, Kurd MF, Rihn JA, Hilibrand AS, Anderson DG, Vaccaro AR, Schroeder GD, Kepler CK.

Spine (Phila Pa 1976). 2019 Nov 18. doi: 10.1097/BRS.0000000000003322. [Epub ahead of print] No abstract available.


Glucose-Responsive Nanoparticles for Rapid and Extended Self-Regulated Insulin Delivery.

Volpatti LR, Matranga MA, Cortinas AB, Delcassian D, Daniel KB, Langer R, Anderson DG.

ACS Nano. 2019 Nov 25. doi: 10.1021/acsnano.9b06395. [Epub ahead of print]


Adenine base editing in an adult mouse model of tyrosinaemia.

Song CQ, Jiang T, Richter M, Rhym LH, Koblan LW, Zafra MP, Schatoff EM, Doman JL, Cao Y, Dow LE, Zhu LJ, Anderson DG, Liu DR, Yin H, Xue W.

Nat Biomed Eng. 2019 Feb 25. doi: 10.1038/s41551-019-0357-8. [Epub ahead of print]


The neuropsychological deficits and dissociations in Huntington Disease-Like 2: A series of case-control studies.

Ferreira-Correia A, Anderson DG, Cockcroft K, Krause A.

Neuropsychologia. 2019 Nov 5;136:107238. doi: 10.1016/j.neuropsychologia.2019.107238. [Epub ahead of print]


Flexible Multielectrode Array for Skeletal Muscle Conditioning, Acetylcholine Receptor Stabilization and Epimysial Recording After Critical Peripheral Nerve Injury.

McAvoy M, Tsosie JK, Vyas KN, Khan OF, Sadtler K, Langer R, Anderson DG.

Theranostics. 2019 Sep 21;9(23):7099-7107. doi: 10.7150/thno.35436. eCollection 2019.


Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis.

Chen PY, Qin L, Li G, Wang Z, Dahlman JE, Malagon-Lopez J, Gujja S, Kauffman KJ, Sun L, Sun H, Zhang X, Aryal B, Canfran-Duque A, Liu R, Kusters P, Sehgal A, Jiao Y, Anderson DG, Gulcher J, Fernandez-Hernando C, Lutgens E, Schwartz MA, Pober JS, Chittenden TW, Tellides G, Simons M.

Nat Metab. 2019 Sep;1(9):912-926. doi: 10.1038/s42255-019-0102-3. Epub 2019 Aug 26.


Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation.

Miao L, Li L, Huang Y, Delcassian D, Chahal J, Han J, Shi Y, Sadtler K, Gao W, Lin J, Doloff JC, Langer R, Anderson DG.

Nat Biotechnol. 2019 Oct;37(10):1174-1185. doi: 10.1038/s41587-019-0247-3. Epub 2019 Sep 30.


Medicaid Reimbursement for Common Spine Procedures: Are Compensation Rates Consistent?

Casper DS, Schroeder GD, McKenzie J, Zmistowski B, Vatson J, Mangan J, Stull J, Kurd M, Rihn JA, Anderson DG, Kaye DI, Radcliff K, Woods B, Hilibrand AS, Vaccaro AR, Kepler CK.

Spine (Phila Pa 1976). 2019 Nov 15;44(22):1585-1590. doi: 10.1097/BRS.0000000000003241.


Are Outcomes of Anterior Cervical Discectomy and Fusion Influenced by Presurgical Depression Symptoms on the Mental Component Score of the Short Form-12 Survey?

Divi SN, Goyal DKC, Mangan JJ, Galetta MS, Nicholson KJ, Fang T, Goyal S, Booth TJ, Tarazona D, Lucasti C, Kaye ID, Kurd MF, Woods BI, Radcliff KE, Rihn JA, Anderson DG, Hilibrand AS, Kepler CK, Vaccaro AR, Schroeder GD.

Spine (Phila Pa 1976). 2019 Sep 6. doi: 10.1097/BRS.0000000000003231. [Epub ahead of print]


Biomaterials for Personalized Cell Therapy.

Facklam AL, Volpatti LR, Anderson DG.

Adv Mater. 2019 Sep 9:e1902005. doi: 10.1002/adma.201902005. [Epub ahead of print] Review.


Frequency of the LRRK2 G2019S mutation in South African patients with Parkinson's disease.

du Toit N, van Coller R, Anderson DG, Carr J, Bardien S.

Neurogenetics. 2019 Oct;20(4):215-218. doi: 10.1007/s10048-019-00588-z. Epub 2019 Sep 6.


Relationship among anesthesia technique, surgical stress, and cognitive dysfunction following spinal surgery: a randomized trial.

Ezhevskaya AA, Ovechkin AM, Prusakova ZB, Zagrekov VI, Mlyavykh SG, Anderson DG.

J Neurosurg Spine. 2019 Sep 6:1-8. doi: 10.3171/2019.4.SPINE184. [Epub ahead of print]


Survivorship Care Plans: Health Actions Taken and Satisfaction After Use.

Hawkins-Taylor C, Carson P, Anderson DG, Carlson A, Kerkvliet J, Cowan J, Gaster S, McClure C, Pugsley L.

Oncol Nurs Forum. 2019 Sep 1;46(5):585-594. doi: 10.1188/19.ONF.585-594.


Fusion technique does not affect short-term patient-reported outcomes for lumbar degenerative disease.

Divi SN, Schroeder GD, Goyal DKC, Radcliff KE, Galetta MS, Hilibrand AS, Anderson DG, Kurd MF, Rihn JA, Kaye ID, Woods BR, Vaccaro AR, Kepler CK.

Spine J. 2019 Dec;19(12):1960-1968. doi: 10.1016/j.spinee.2019.07.014. Epub 2019 Jul 26.


Non-mobile Adjacent Level Cervical Spondylolisthesis Does Not Always Require Fusion in Patients Undergoing ACDF.

Segar AH, Divi SN, Tarazona D, Fried T, Sandhu H, Kaye ID, Kepler CK, Kurd MF, Woods BI, Hilibrand AS, Radcliff KE, Rihn JA, Anderson DG, Vaccaro AR, Schroeder GD.

Spine (Phila Pa 1976). 2019 Sep;44(18):1287-1293. doi: 10.1097/BRS.0000000000003070.


Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations.

Farah S, Doloff JC, Müller P, Sadraei A, Han HJ, Olafson K, Vyas K, Tam HH, Hollister-Lock J, Kowalski PS, Griffin M, Meng A, McAvoy M, Graham AC, McGarrigle J, Oberholzer J, Weir GC, Greiner DL, Langer R, Anderson DG.

Nat Mater. 2019 Aug;18(8):892-904. doi: 10.1038/s41563-019-0377-5. Epub 2019 Jun 24.


Huntington Disease-Like 2.

Anderson DG, Krause A, Margolis RL.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019.
2004 Jan 30 [updated 2019 Jun 27].


mRNA Delivery for Therapeutic Anti-HER2 Antibody Expression In Vivo.

Rybakova Y, Kowalski PS, Huang Y, Gonzalez JT, Heartlein MW, DeRosa F, Delcassian D, Anderson DG.

Mol Ther. 2019 Aug 7;27(8):1415-1423. doi: 10.1016/j.ymthe.2019.05.012. Epub 2019 May 18.


Intraosseous Basivertebral Nerve Ablation for the Treatment of Chronic Low Back Pain: 2-Year Results From a Prospective Randomized Double-Blind Sham-Controlled Multicenter Study.

Fischgrund JS, Rhyne A, Franke J, Sasso R, Kitchel S, Bae H, Yeung C, Truumees E, Schaufele M, Yuan P, Vajkoczy P, Depalma M, Anderson DG, Thibodeau L, Meyer B.

Int J Spine Surg. 2019 Apr 30;13(2):110-119. doi: 10.14444/6015. eCollection 2019 Apr.


Strategies, design, and chemistry in siRNA delivery systems.

Dong Y, Siegwart DJ, Anderson DG.

Adv Drug Deliv Rev. 2019 Apr;144:133-147. doi: 10.1016/j.addr.2019.05.004. Epub 2019 May 15. Review.


Comparison of the Huntington's Disease like 2 and Huntington's Disease Clinical Phenotypes.

Anderson DG, Ferreira-Correia A, Rodrigues FB, Aziz NA, Carr J, Wild EJ, Margolis RL, Krause A.

Mov Disord Clin Pract. 2019 Mar 12;6(4):302-311. doi: 10.1002/mdc3.12742. eCollection 2019 Apr.


Biomanufacturing for clinically advanced cell therapies.

Aijaz A, Li M, Smith D, Khong D, LeBlon C, Fenton OS, Olabisi RM, Libutti S, Tischfield J, Maus MV, Deans R, Barcia RN, Anderson DG, Ritz J, Preti R, Parekkadan B.

Nat Biomed Eng. 2018 Jun;2(6):362-376. doi: 10.1038/s41551-018-0246-6. Epub 2018 Jun 11. Review.


Comparison of Short-term Outcomes After Lumbar Fusion Between an Orthopedic Specialty Hospital and Tertiary Referral Center.

Kreitz TM, Tarazona D, Padegimas EM, Foltz C, Kepler CK, Anderson DG, Vaccaro AR, Hilibrand AS, Schroeder GD.

Spine (Phila Pa 1976). 2019 May 1;44(9):652-658. doi: 10.1097/BRS.0000000000002911.


Polyimide Electrode-Based Electrical Stimulation Impedes Early Stage Muscle Graft Regeneration.

Srinivasan S, Vyas K, McAvoy M, Calvaresi P, Khan OF, Langer R, Anderson DG, Herr H.

Front Neurol. 2019 Mar 22;10:252. doi: 10.3389/fneur.2019.00252. eCollection 2019.


Reduction of measurement noise in a continuous glucose monitor by coating the sensor with a zwitterionic polymer.

Xie X, Doloff JC, Yesilyurt V, Sadraei A, McGarrigle JJ, Omami M, Veiseh O, Farah S, Isa D, Ghani S, Joshi I, Vegas A, Li J, Wang W, Bader A, Tam HH, Tao J, Chen HJ, Yang B, Williamson KA, Oberholzer J, Langer R, Anderson DG.

Nat Biomed Eng. 2018 Dec;2(12):894-906. doi: 10.1038/s41551-018-0273-3. Epub 2018 Jul 30.


RNA Circularization Diminishes Immunogenicity and Can Extend Translation Duration In Vivo.

Wesselhoeft RA, Kowalski PS, Parker-Hale FC, Huang Y, Bisaria N, Anderson DG.

Mol Cell. 2019 May 2;74(3):508-520.e4. doi: 10.1016/j.molcel.2019.02.015. Epub 2019 Mar 19.


Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques.

Bochenek MA, Veiseh O, Vegas AJ, McGarrigle JJ, Qi M, Marchese E, Omami M, Doloff JC, Mendoza-Elias J, Nourmohammadzadeh M, Khan A, Yeh CC, Xing Y, Isa D, Ghani S, Li J, Landry C, Bader AR, Olejnik K, Chen M, Hollister-Lock J, Wang Y, Greiner DL, Weir GC, Strand BL, Rokstad AMA, Lacik I, Langer R, Anderson DG, Oberholzer J.

Nat Biomed Eng. 2018 Nov;2(11):810-821. doi: 10.1038/s41551-018-0275-1. Epub 2018 Aug 13.


Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1.

McCann JV, Xiao L, Kim DJ, Khan OF, Kowalski PS, Anderson DG, Pecot CV, Azam SH, Parker JS, Tsai YS, Wolberg AS, Turner SD, Tatsumi K, Mackman N, Dudley AC.

J Clin Invest. 2019 Mar 11;130:1654-1670. doi: 10.1172/JCI123106. eCollection 2019 Mar 11.


Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery.

Kowalski PS, Rudra A, Miao L, Anderson DG.

Mol Ther. 2019 Apr 10;27(4):710-728. doi: 10.1016/j.ymthe.2019.02.012. Epub 2019 Feb 19. Review.


Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning.

Spanoudaki V, Doloff JC, Huang W, Norcross SR, Farah S, Langer R, Anderson DG.

Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4861-4870. doi: 10.1073/pnas.1815909116. Epub 2019 Feb 26.


BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.

Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan J 3rd, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY.

Circulation. 2019 May 7;139(19):2238-2255. doi: 10.1161/CIRCULATIONAHA.118.035889.


Faecal biomarkers can distinguish specific mammalian species in modern and past environments.

Harrault L, Milek K, Jardé E, Jeanneau L, Derrien M, Anderson DG.

PLoS One. 2019 Feb 7;14(2):e0211119. doi: 10.1371/journal.pone.0211119. eCollection 2019.


Emerging differences between Huntington's disease-like 2 and Huntington's disease: A comparison using MRI brain volumetry.

Anderson DG, Haagensen M, Ferreira-Correia A, Pierson R, Carr J, Krause A, Margolis RL.

Neuroimage Clin. 2019;21:101666. doi: 10.1016/j.nicl.2019.101666. Epub 2019 Jan 7.


CRISPR-Cas: a tool for cancer research and therapeutics.

Yin H, Xue W, Anderson DG.

Nat Rev Clin Oncol. 2019 May;16(5):281-295. doi: 10.1038/s41571-019-0166-8. Review.


Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium.

Patel AK, Kaczmarek JC, Bose S, Kauffman KJ, Mir F, Heartlein MW, DeRosa F, Langer R, Anderson DG.

Adv Mater. 2019 Feb;31(8):e1805116. doi: 10.1002/adma.201805116. Epub 2019 Jan 4.


Medicaid Reimbursement for Common Orthopedic Procedures Is Not Consistent.

Casper DS, Schroeder GD, Zmistowski B, Rihn JA, Anderson DG, Hilibrand AS, Vaccaro AR, Kepler CK.

Orthopedics. 2019 Mar 1;42(2):e193-e196. doi: 10.3928/01477447-20181227-06. Epub 2019 Jan 3.


The Total Cost to the Health Care System in Medicare and Medicaid Patients for the Treatment of Cervical Myelopathy.

Schroeder GD, McKenzie JC, Casper DS, Kurd MF, Hilibrand AS, Woods BI, Radcliff KE, Rihn JA, Anderson DG, Vaccaro AR, Kepler C.

Clin Spine Surg. 2019 Feb;32(1):32-37. doi: 10.1097/BSD.0000000000000757.


Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.

Nakano T, Katsuki S, Chen M, Decano JL, Halu A, Lee LH, Pestana DVS, Kum AST, Kuromoto RK, Golden WS, Boff MS, Guimaraes GC, Higashi H, Kauffman KJ, Maejima T, Suzuki T, Iwata H, Barabási AL, Aster JC, Anderson DG, Sharma A, Singh SA, Aikawa E, Aikawa M.

Circulation. 2019 Jan 2;139(1):78-96. doi: 10.1161/CIRCULATIONAHA.118.034588.


Longer Preoperative Duration of Symptoms Negatively Affects Health-related Quality of Life After Surgery for Cervical Radiculopathy.

Tarazona D, Boody B, Hilibrand AS, Stull J, Bell K, Fang T, Goyal D, Galetta M, Kaye D, Kepler CK, Kurd MF, Woods BI, Radcliff KE, Rihn JA, Anderson DG, Vaccaro AR, Schroeder GD.

Spine (Phila Pa 1976). 2019 May 15;44(10):685-690. doi: 10.1097/BRS.0000000000002924.


Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis.

Meyer IS, Goetzke CC, Kespohl M, Sauter M, Heuser A, Eckstein V, Vornlocher HP, Anderson DG, Haas J, Meder B, Katus HA, Klingel K, Beling A, Leuschner F.

Front Immunol. 2018 Oct 8;9:2303. doi: 10.3389/fimmu.2018.02303. eCollection 2018.


Utilization of Time-driven Activity-based Costing to Determine the True Cost of a Single or 2-level Anterior Cervical Discectomy and Fusion.

Schroeder GD, Hilibrand AS, Kepler CK, McKenzie JC, Nicholson KJ, Stawicki C, Paul J, Kumar P, Hollern DA, Murphy H, Milhouse PW, Kurd MF, Woods BI, Radcliff KE, Anderson DG, Vaccaro AR, Rihn JA.

Clin Spine Surg. 2018 Dec;31(10):452-456. doi: 10.1097/BSD.0000000000000728.


Optimization of a Degradable Polymer-Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells.

Kaczmarek JC, Kauffman KJ, Fenton OS, Sadtler K, Patel AK, Heartlein MW, DeRosa F, Anderson DG.

Nano Lett. 2018 Oct 10;18(10):6449-6454. doi: 10.1021/acs.nanolett.8b02917. Epub 2018 Sep 20.


Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs.

Fenton OS, Kauffman KJ, McClellan RL, Kaczmarek JC, Zeng MD, Andresen JL, Rhym LH, Heartlein MW, DeRosa F, Anderson DG.

Angew Chem Int Ed Engl. 2018 Oct 8;57(41):13582-13586. doi: 10.1002/anie.201809056. Epub 2018 Sep 14.


Engineering circular RNA for potent and stable translation in eukaryotic cells.

Wesselhoeft RA, Kowalski PS, Anderson DG.

Nat Commun. 2018 Jul 6;9(1):2629. doi: 10.1038/s41467-018-05096-6.


Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery.

Kowalski PS, Capasso Palmiero U, Huang Y, Rudra A, Langer R, Anderson DG.

Adv Mater. 2018 Jul 5:e1801151. doi: 10.1002/adma.201801151. [Epub ahead of print]


Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles.

Khan OF, Kowalski PS, Doloff JC, Tsosie JK, Bakthavatchalu V, Winn CB, Haupt J, Jamiel M, Langer R, Anderson DG.

Sci Adv. 2018 Jun 27;4(6):eaar8409. doi: 10.1126/sciadv.aar8409. eCollection 2018 Jun.


Five-year results of a clinical pilot study utilizing a pedicle-lengthening osteotomy for the treatment of lumbar spinal stenosis.

Mlyavykh S, Ludwig SC, Kepler CK, Anderson DG.

J Neurosurg Spine. 2018 Sep;29(3):241-249. doi: 10.3171/2017.11.SPINE16664. Epub 2018 Jun 1.


Are Patients Undergoing an Anterior Cervical Discectomy and Fusion Treated Differently at a Physician-owned Hospital?

Schroeder GD, Kurd MF, Kepler CK, Radcliff KE, Maltenfort MG, Murphy H, Rihn JA, Anderson DG, Hilibrand AS, Vaccaro AR.

Clin Spine Surg. 2018 Jun;31(5):211-215. doi: 10.1097/BSD.0000000000000577.


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