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Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism.

Weivoda MM, Chew CK, Monroe DG, Farr JN, Atkinson EJ, Geske JR, Eckhardt B, Thicke B, Ruan M, Tweed AJ, McCready LK, Rizza RA, Matveyenko A, Kassem M, Andersen TL, Vella A, Drake MT, Clarke BL, Oursler MJ, Khosla S.

Nat Commun. 2020 Jan 7;11(1):87. doi: 10.1038/s41467-019-14003-6.


High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome.

Moldovan LI, Hansen TB, Venø MT, Okholm TLH, Andersen TL, Hager H, Iversen L, Kjems J, Johansen C, Kristensen LS.

BMC Med Genomics. 2019 Nov 27;12(1):174. doi: 10.1186/s12920-019-0616-2.


Bone marrow adipose tissue does not express UCP1 during development or adrenergic-induced remodeling.

Craft CS, Robles H, Lorenz MR, Hilker ED, Magee KL, Andersen TL, Cawthorn WP, MacDougald OA, Harris CA, Scheller EL.

Sci Rep. 2019 Nov 22;9(1):17427. doi: 10.1038/s41598-019-54036-x.


The generation of enlarged eroded pores upon existing intracortical canals is a major contributor to endocortical trabecularization.

Andreasen CM, Bakalova LP, Brüel A, Hauge EM, Kiil BJ, Delaisse JM, Kersh ME, Thomsen JS, Andersen TL.

Bone. 2020 Jan;130:115127. doi: 10.1016/j.bone.2019.115127. Epub 2019 Nov 2.


Improving contrast and detectability - imaging with [55Co]Co-DOTATATE in comparison with [64Cu]Cu-DOTATATE and [68Ga]Ga-DOTATATE.

Andersen TL, Baun C, Olsen BB, Dam JH, Thisgaard H.

J Nucl Med. 2019 Sep 13. pii: jnumed.119.233015. doi: 10.2967/jnumed.119.233015. [Epub ahead of print]


Hybrid PET/MRI in major cancers: a scoping review.

Morsing A, Hildebrandt MG, Vilstrup MH, Wallenius SE, Gerke O, Petersen H, Johansen A, Andersen TL, Høilund-Carlsen PF.

Eur J Nucl Med Mol Imaging. 2019 Sep;46(10):2138-2151. doi: 10.1007/s00259-019-04402-8. Epub 2019 Jul 2.


Coordination of Fusion and Trafficking of Pre-osteoclasts at the Marrow-Bone Interface.

Søe K, Andersen TL, Hinge M, Rolighed L, Marcussen N, Delaisse JM.

Calcif Tissue Int. 2019 Oct;105(4):430-445. doi: 10.1007/s00223-019-00575-4. Epub 2019 Jun 25.


Obesity-Associated Hypermetabolism and Accelerated Senescence of Bone Marrow Stromal Stem Cells Suggest a Potential Mechanism for Bone Fragility.

Tencerova M, Frost M, Figeac F, Nielsen TK, Ali D, Lauterlein JL, Andersen TL, Haakonsson AK, Rauch A, Madsen JS, Ejersted C, Højlund K, Kassem M.

Cell Rep. 2019 May 14;27(7):2050-2062.e6. doi: 10.1016/j.celrep.2019.04.066.


Catabolic activity of osteoblast lineage cells contributes to osteoclastic bone resorption in vitro.

Pirapaharan DC, Olesen JB, Andersen TL, Christensen SB, Kjærsgaard-Andersen P, Delaisse JM, Søe K.

J Cell Sci. 2019 May 15;132(10). pii: jcs229351. doi: 10.1242/jcs.229351.


Innervation is higher above Bone Remodeling Surfaces and in Cortical Pores in Human Bone: Lessons from patients with primary hyperparathyroidism.

Sayilekshmy M, Hansen RB, Delaissé JM, Rolighed L, Andersen TL, Heegaard AM.

Sci Rep. 2019 Mar 29;9(1):5361. doi: 10.1038/s41598-019-41779-w.


KIAA1199 is a secreted molecule that enhances osteoblastic stem cell migration and recruitment.

Chen L, Shi K, Andersen TL, Qiu W, Kassem M.

Cell Death Dis. 2019 Feb 12;10(2):126. doi: 10.1038/s41419-018-1202-9.


Absence of an osteopetrosis phenotype in IKBKG (NEMO) mutation-positive women: A case-control study.

Frost M, Tencerova M, Andreasen CM, Andersen TL, Ejersted C, Svaneby D, Qui W, Kassem M, Zarei A, McAlister WH, Veis DJ, Whyte MP, Frederiksen AL.

Bone. 2019 Apr;121:243-254. doi: 10.1016/j.bone.2019.01.014. Epub 2019 Jan 16.


Understanding age-induced cortical porosity in women: Is a negative BMU balance in quiescent osteons a major contributor?

Andreasen CM, Delaisse JM, van der Eerden BCJ, van Leeuwen JPTM, Ding M, Andersen TL.

Bone. 2018 Dec;117:70-82. doi: 10.1016/j.bone.2018.09.011. Epub 2018 Sep 18.


Septins are critical regulators of osteoclastic bone resorption.

Møller AMJ, Füchtbauer EM, Brüel A, Andersen TL, Borggaard XG, Pavlos NJ, Thomsen JS, Pedersen FS, Delaisse JM, Søe K.

Sci Rep. 2018 Aug 29;8(1):13016. doi: 10.1038/s41598-018-31159-1.


Synthesis of Aliphatic Carboxamides Mediated by Nickel NN2 -Pincer Complexes and Adaptation to Carbon-Isotope Labeling.

Neumann KT, Donslund AS, Andersen TL, Nielsen DU, Skrydstrup T.

Chemistry. 2018 Oct 9;24(56):14946-14949. doi: 10.1002/chem.201804077. Epub 2018 Sep 11.


Intracortical Bone Mechanics Are Related to Pore Morphology and Remodeling in Human Bone.

Bakalova LP, Andreasen CM, Thomsen JS, Brüel A, Hauge EM, Kiil BJ, Delaisse JM, Andersen TL, Kersh ME.

J Bone Miner Res. 2018 Dec;33(12):2177-2185. doi: 10.1002/jbmr.3561. Epub 2018 Aug 29.


SPIDR: small-molecule peptide-influenced drug repurposing.

King MD, Long T, Pfalmer DL, Andersen TL, McDougal OM.

BMC Bioinformatics. 2018 Apr 16;19(1):138. doi: 10.1186/s12859-018-2153-y.


Carbonylative Coupling of Alkyl Zinc Reagents with Benzyl Bromides Catalyzed by a Nickel/NN2  Pincer Ligand Complex.

Andersen TL, Donslund AS, Neumann KT, Skrydstrup T.

Angew Chem Int Ed Engl. 2018 Jan 15;57(3):800-804. doi: 10.1002/anie.201710089. Epub 2017 Dec 18.


Understanding Age-Induced Cortical Porosity in Women: The Accumulation and Coalescence of Eroded Cavities Upon Existing Intracortical Canals Is the Main Contributor.

Andreasen CM, Delaisse JM, van der Eerden BC, van Leeuwen JP, Ding M, Andersen TL.

J Bone Miner Res. 2018 Apr;33(4):606-620. doi: 10.1002/jbmr.3354. Epub 2018 Jan 4.


Effects of substitute coated with hyaluronic acid or poly-lactic acid on implant fixation: Experimental study in ovariectomized and glucocorticoid-treated sheep.

Andreasen CM, Ding M, Andersen TL, Overgaard S.

J Tissue Eng Regen Med. 2018 Feb;12(2):e1122-e1130. doi: 10.1002/term.2447. Epub 2017 Jul 25.


Application of Methyl Bisphosphine-Ligated Palladium Complexes for Low Pressure N-11 C-Acetylation of Peptides.

Andersen TL, Nordeman P, Christoffersen HF, Audrain H, Antoni G, Skrydstrup T.

Angew Chem Int Ed Engl. 2017 Apr 10;56(16):4549-4553. doi: 10.1002/anie.201700446. Epub 2017 Mar 16.


Coupling of Bone Resorption and Formation in Real Time: New Knowledge Gained From Human Haversian BMUs.

Lassen NE, Andersen TL, Pløen GG, Søe K, Hauge EM, Harving S, Eschen GET, Delaisse JM.

J Bone Miner Res. 2017 Jul;32(7):1395-1405. doi: 10.1002/jbmr.3091. Epub 2017 Feb 28.


Legumain Regulates Differentiation Fate of Human Bone Marrow Stromal Cells and Is Altered in Postmenopausal Osteoporosis.

Jafari A, Qanie D, Andersen TL, Zhang Y, Chen L, Postert B, Parsons S, Ditzel N, Khosla S, Johansen HT, Kjærsgaard-Andersen P, Delaisse JM, Abdallah BM, Hesselson D, Solberg R, Kassem M.

Stem Cell Reports. 2017 Feb 14;8(2):373-386. doi: 10.1016/j.stemcr.2017.01.003. Epub 2017 Feb 2.


CRMP4 Inhibits Bone Formation by Negatively Regulating BMP and RhoA Signaling.

Abdallah BM, Figeac F, Larsen KH, Ditzel N, Keshari P, Isa A, Jafari A, Andersen TL, Delaisse JM, Goshima Y, Ohshima T, Kassem M.

J Bone Miner Res. 2017 May;32(5):913-926. doi: 10.1002/jbmr.3069. Epub 2017 Feb 2.


The efficacy of poly-d,l-lactic acid- and hyaluronic acid-coated bone substitutes on implant fixation in sheep.

Andreasen CM, Henriksen SS, Ding M, Theilgaard N, Andersen TL, Overgaard S.

J Orthop Translat. 2016 Aug 25;8:12-19. doi: 10.1016/ eCollection 2017 Jan.


An ATP Binding Cassette Transporter Mediates the Uptake of α-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates.

Ejby M, Fredslund F, Andersen JM, Vujičić Žagar A, Henriksen JR, Andersen TL, Svensson B, Slotboom DJ, Abou Hachem M.

J Biol Chem. 2016 Sep 16;291(38):20220-31. doi: 10.1074/jbc.M116.746529. Epub 2016 Aug 8.


Direct Access to α,α-Difluoroacylated Arenes by Palladium-Catalyzed Carbonylation of (Hetero)Aryl Boronic Acid Derivatives.

Andersen TL, Frederiksen MW, Domino K, Skrydstrup T.

Angew Chem Int Ed Engl. 2016 Aug 22;55(35):10396-400. doi: 10.1002/anie.201604152. Epub 2016 Jun 27.


Correction: Bone Canopies in Pediatric Renal Osteodystrophy.

Pereira RC, Andersen TL, Friedman PA, Tumber N, Salusky IB, Wesseling-Perry K.

PLoS One. 2016 May 11;11(5):e0155663. doi: 10.1371/journal.pone.0155663. eCollection 2016.


Bone Canopies in Pediatric Renal Osteodystrophy.

Pereira RC, Andersen TL, Friedman PA, Tumber N, Salusky IB, Wesseling-Perry K.

PLoS One. 2016 Apr 5;11(4):e0152871. doi: 10.1371/journal.pone.0152871. eCollection 2016. Erratum in: PLoS One. 2016;11(5):e0155663.


Early reversal cells in adult human bone remodeling: osteoblastic nature, catabolic functions and interactions with osteoclasts.

Abdelgawad ME, Delaisse JM, Hinge M, Jensen PR, Alnaimi RW, Rolighed L, Engelholm LH, Marcussen N, Andersen TL.

Histochem Cell Biol. 2016 Jun;145(6):603-15. doi: 10.1007/s00418-016-1414-y. Epub 2016 Feb 9.


Rapid and Efficient Conversion of (11) CO2 to (11) CO through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations.

Nordeman P, Friis SD, Andersen TL, Audrain H, Larhed M, Skrydstrup T, Antoni G.

Chemistry. 2015 Dec 1;21(49):17601-4. doi: 10.1002/chem.201503262. Epub 2015 Oct 23.


Osteoporosis 2014.

Yuan LQ, Ouyang HW, Andersen TL, Jiang Y, Pantano F, Shan PF.

Int J Endocrinol. 2015;2015:567593. doi: 10.1155/2015/567593. Epub 2015 Jul 28. No abstract available.


High-dose therapy improves the bone remodelling compartment canopy coverage and bone formation in multiple myeloma.

Hinge M, Delaisse JM, Plesner T, Clasen-Linde E, Salomo M, Andersen TL.

Br J Haematol. 2015 Nov;171(3):355-65. doi: 10.1111/bjh.13584. Epub 2015 Jul 27.


A reversal phase arrest uncoupling the bone formation and resorption contributes to the bone loss in glucocorticoid treated ovariectomised aged sheep.

Andreasen CM, Ding M, Overgaard S, Bollen P, Andersen TL.

Bone. 2015 Jun;75:32-9. doi: 10.1016/j.bone.2015.02.014. Epub 2015 Feb 14.


Efficient 11C-carbonylation of isolated aryl palladium complexes for PET: application to challenging radiopharmaceutical synthesis.

Andersen TL, Friis SD, Audrain H, Nordeman P, Antoni G, Skrydstrup T.

J Am Chem Soc. 2015 Feb 4;137(4):1548-55. doi: 10.1021/ja511441u. Epub 2015 Jan 26.


General method for the preparation of active esters by palladium-catalyzed alkoxycarbonylation of aryl bromides.

de Almeida AM, Andersen TL, Lindhardt AT, de Almeida MV, Skrydstrup T.

J Org Chem. 2015 Feb 6;80(3):1920-8. doi: 10.1021/jo5025464. Epub 2015 Jan 21.


A joined role of canopy and reversal cells in bone remodeling--lessons from glucocorticoid-induced osteoporosis.

Jensen PR, Andersen TL, Hauge EM, Bollerslev J, Delaissé JM.

Bone. 2015 Apr;73:16-23. doi: 10.1016/j.bone.2014.12.004. Epub 2014 Dec 10.


Does collagen trigger the recruitment of osteoblasts into vacated bone resorption lacunae during bone remodeling?

Abdelgawad ME, Søe K, Andersen TL, Merrild DM, Christiansen P, Kjærsgaard-Andersen P, Delaisse JM.

Bone. 2014 Oct;67:181-8. doi: 10.1016/j.bone.2014.07.012. Epub 2014 Jul 11.


Two-chamber hydrogen generation and application: access to pressurized deuterium gas.

Modvig A, Andersen TL, Taaning RH, Lindhardt AT, Skrydstrup T.

J Org Chem. 2014 Jun 20;79(12):5861-8. doi: 10.1021/jo500801t. Epub 2014 Jun 11.


Correlation between absence of bone remodeling compartment canopies, reversal phase arrest, and deficient bone formation in post-menopausal osteoporosis.

Andersen TL, Hauge EM, Rolighed L, Bollerslev J, Kjærsgaard-Andersen P, Delaisse JM.

Am J Pathol. 2014 Apr;184(4):1142-1151. doi: 10.1016/j.ajpath.2013.12.005. Epub 2014 Feb 5.


Osteoblast recruitment routes in human cancellous bone remodeling.

Kristensen HB, Andersen TL, Marcussen N, Rolighed L, Delaisse JM.

Am J Pathol. 2014 Mar;184(3):778-89. doi: 10.1016/j.ajpath.2013.11.022. Epub 2014 Jan 9.


A supra-cellular model for coupling of bone resorption to formation during remodeling: lessons from two bone resorption inhibitors affecting bone formation differently.

Jensen PR, Andersen TL, Pennypacker BL, Duong LT, Engelholm LH, Delaissé JM.

Biochem Biophys Res Commun. 2014 Jan 10;443(2):694-9. doi: 10.1016/j.bbrc.2013.12.036. Epub 2013 Dec 12.


The bone resorption inhibitors odanacatib and alendronate affect post-osteoclastic events differently in ovariectomized rabbits.

Jensen PR, Andersen TL, Pennypacker BL, Duong LT, Delaissé JM.

Calcif Tissue Int. 2014 Feb;94(2):212-22. doi: 10.1007/s00223-013-9800-0. Epub 2013 Oct 2.


DockoMatic 2.0: high throughput inverse virtual screening and homology modeling.

Bullock C, Cornia N, Jacob R, Remm A, Peavey T, Weekes K, Mallory C, Oxford JT, McDougal OM, Andersen TL.

J Chem Inf Model. 2013 Aug 26;53(8):2161-70. doi: 10.1021/ci400047w. Epub 2013 Aug 8.


Understanding coupling between bone resorption and formation: are reversal cells the missing link?

Andersen TL, Abdelgawad ME, Kristensen HB, Hauge EM, Rolighed L, Bollerslev J, Kjærsgaard-Andersen P, Delaisse JM.

Am J Pathol. 2013 Jul;183(1):235-46. doi: 10.1016/j.ajpath.2013.03.006. Epub 2013 Jun 6.


Birth weight and adult bone metabolism are unrelated: results from birth weight-discordant monozygotic twins.

Frost M, Petersen I, Andersen TL, Langdahl BL, Buhl T, Christiansen L, Brixen K, Christensen K.

J Bone Miner Res. 2013 Dec;28(12):2561-9. doi: 10.1002/jbmr.1995.


Palladium-catalyzed synthesis of aromatic carboxylic acids with silacarboxylic acids.

Friis SD, Andersen TL, Skrydstrup T.

Org Lett. 2013 Mar 15;15(6):1378-81. doi: 10.1021/ol4003465. Epub 2013 Feb 26.


Increased presence of capillaries next to remodeling sites in adult human cancellous bone.

Kristensen HB, Andersen TL, Marcussen N, Rolighed L, Delaisse JM.

J Bone Miner Res. 2013 Mar;28(3):574-85. doi: 10.1002/jbmr.1760.


Synthesis and evaluation of silanediols as highly selective uncompetitive inhibitors of human neutrophil elastase.

Madsen JL, Andersen TL, Santamaria S, Nagase H, Enghild JJ, Skrydstrup T.

J Med Chem. 2012 Sep 13;55(17):7900-8. doi: 10.1021/jm301000k. Epub 2012 Aug 28.


Immunolocalization of RANK and RANKL along the root surface and in the periodontal membrane of human primary and permanent teeth.

Bille ML, Thomsen B, Andersen TL, Kjær I.

Acta Odontol Scand. 2012 Jul;70(4):265-71. doi: 10.3109/00016357.2011.641585. Epub 2012 Mar 8.


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