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Simultaneous detection of zinc and its pathway metabolites using MALDI MS imaging of prostate tissue.

Andersen MK, Krossa S, Høiem TS, Buchholz R, Claes BSR, Balluff B, Ellis SR, Richardsen E, Bertilsson H, Heeren RMA, Bathen TF, Karst U, Giskeødegård GF, Tessem MB.

Anal Chem. 2020 Jan 16. doi: 10.1021/acs.analchem.9b04903. [Epub ahead of print]


The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome.

Brieghel C, da Cunha-Bang C, Yde CW, Schmidt AY, Kinalis S, Nadeu F, Andersen MA, Jacobsen LO, Andersen MK, Pedersen LB, Delgado J, Baumann T, Mattsson M, Mansouri L, Rosenquist R, Campo E, Nielsen FC, Niemann CU.

Clin Cancer Res. 2020 Jan 9. pii: clincanres.4158.2018. doi: 10.1158/1078-0432.CCR-18-4158. [Epub ahead of print]


A colonized general practice? A critical habermasian analysis of how general practitioners experience defensive medicine in their everyday working life.

Assing Hvidt E, Bjørnskov Pedersen L, Lykkegaard J, Møller Pedersen K, Andersen MK.

Health (London). 2019 Jun 20:1363459319857461. doi: 10.1177/1363459319857461. [Epub ahead of print]


Global microRNA profiling of metastatic conjunctival melanoma.

Mikkelsen LH, Andersen MK, Andreasen S, Larsen AC, Tan Q, Toft PB, Wadt K, Heegaard S.

Melanoma Res. 2019 Oct;29(5):465-473. doi: 10.1097/CMR.0000000000000606.


The central nervous system and muscular system play different roles for chill coma onset and recovery in insects.

Andersen MK, Overgaard J.

Comp Biochem Physiol A Mol Integr Physiol. 2019 Jul;233:10-16. doi: 10.1016/j.cbpa.2019.03.015. Epub 2019 Mar 22.


Addressing the room for improvement in management of acute promyelocytic leukemia.

Nørgaard JM, Friis LS, Kristensen JS, Severinsen MT, Mølle I, Marcher CW, Møller P, Schoellkopf C, Nielsen OJ, Preiss BS, Andersen MK, Kjeldsen E, Medeiros BC, Østgård LSG; Danish Acute Leukemia Group.

Eur J Haematol. 2019 Jun;102(6):479-485. doi: 10.1111/ejh.13229. Epub 2019 Apr 7.


Orbital precursor B-lymphoblastic lymphoma involving the extraocular muscles in a 56-year-old male and a review of the literature.

Ejstrup R, Mikkelsen LH, Andersen MK, Clasen-Linde E, Gjerdrum LMR, Safavi S, Heegaard S.

Oncol Lett. 2019 Feb;17(2):1477-1482. doi: 10.3892/ol.2018.9725. Epub 2018 Nov 19.


Fluctuating thermal regime preserves physiological homeostasis and reproductive capacity in Drosophila suzukii.

Grumiaux C, Andersen MK, Colinet H, Overgaard J.

J Insect Physiol. 2019 Feb - Mar;113:33-41. doi: 10.1016/j.jinsphys.2019.01.001. Epub 2019 Jan 4.


Cold exposure causes cell death by depolarization-mediated Ca2+ overload in a chill-susceptible insect.

Bayley JS, Winther CB, Andersen MK, Grønkjær C, Nielsen OB, Pedersen TH, Overgaard J.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9737-E9744. doi: 10.1073/pnas.1813532115. Epub 2018 Sep 25.


First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes.

Cousminer DL, Ahlqvist E, Mishra R, Andersen MK, Chesi A, Hawa MI, Davis A, Hodge KM, Bradfield JP, Zhou K, Guy VC, Åkerlund M, Wod M, Fritsche LG, Vestergaard H, Snyder J, Højlund K, Linneberg A, Käräjämäki A, Brandslund I, Kim CE, Witte D, Sørgjerd EP, Brillon DJ, Pedersen O, Beck-Nielsen H, Grarup N, Pratley RE, Rickels MR, Vella A, Ovalle F, Melander O, Harris RI, Varvel S, Grill VER; Bone Mineral Density in Childhood Study, Hakonarson H, Froguel P, Lonsdale JT, Mauricio D, Schloot NC, Khunti K, Greenbaum CJ, Åsvold BO, Yderstræde KB, Pearson ER, Schwartz S, Voight BF, Hansen T, Tuomi T, Boehm BO, Groop L, Leslie RD, Grant SFA.

Diabetes Care. 2018 Nov;41(11):2396-2403. doi: 10.2337/dc18-1032. Epub 2018 Sep 25.


Integrative metabolic and transcriptomic profiling of prostate cancer tissue containing reactive stroma.

Andersen MK, Rise K, Giskeødegård GF, Richardsen E, Bertilsson H, Størkersen Ø, Bathen TF, Rye M, Tessem MB.

Sci Rep. 2018 Sep 24;8(1):14269. doi: 10.1038/s41598-018-32549-1.


Implementation of the safewards model to reduce the use of coercive measures in adult psychiatric inpatient units: An interrupted time-series analysis.

Stensgaard L, Andersen MK, Nordentoft M, Hjorthøj C.

J Psychiatr Res. 2018 Oct;105:147-152. doi: 10.1016/j.jpsychires.2018.08.026. Epub 2018 Sep 8.


Putative new childhood leukemia cancer predisposition syndrome caused by germline bi-allelic missense mutations in DDX41.

Diness BR, Risom L, Frandsen TL, Hansen B, Andersen MK, Schmiegelow K, Wadt KAW.

Genes Chromosomes Cancer. 2018 Dec;57(12):670-674. doi: 10.1002/gcc.22680. Epub 2018 Oct 11.


Genetics of metabolic traits in Greenlanders: lessons from an isolated population.

Andersen MK, Hansen T.

J Intern Med. 2018 Nov;284(5):464-477. doi: 10.1111/joim.12814. Epub 2018 Aug 12. Review.


Defensive medicine in primary health care.

Lykkegaard J, Andersen MKK, Nexøe J, Hvidt EA.

Scand J Prim Health Care. 2018 Sep;36(3):225-226. doi: 10.1080/02813432.2018.1499483. Epub 2018 Aug 8. No abstract available.


Genetic Aspects of Latent Autoimmune Diabetes in Adults: A Mini-Review.

Andersen MK, Hansen T.

Curr Diabetes Rev. 2019;15(3):194-198. doi: 10.2174/1573399814666180730123226. Review.


Can external interventions crowd in intrinsic motivation? A cluster randomised field experiment on mandatory accreditation of general practice in Denmark.

Pedersen LB, Andersen MKK, Jensen UT, Waldorff FB, Jacobsen CB.

Soc Sci Med. 2018 Aug;211:224-233. doi: 10.1016/j.socscimed.2018.06.023. Epub 2018 Jun 22.


Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population.

Grarup N, Moltke I, Andersen MK, Bjerregaard P, Larsen CVL, Dahl-Petersen IK, Jørsboe E, Tiwari HK, Hopkins SE, Wiener HW, Boyer BB, Linneberg A, Pedersen O, Jørgensen ME, Albrechtsen A, Hansen T.

Diabetologia. 2018 Sep;61(9):2005-2015. doi: 10.1007/s00125-018-4659-2. Epub 2018 Jun 20.


NMR-Based Prostate Cancer Metabolomics.

Euceda LR, Andersen MK, Tessem MB, Moestue SA, Grinde MT, Bathen TF.

Methods Mol Biol. 2018;1786:237-257. doi: 10.1007/978-1-4939-7845-8_14.


Central nervous system shutdown underlies acute cold tolerance in tropical and temperate Drosophila species.

Andersen MK, Jensen NJS, Robertson RM, Overgaard J.

J Exp Biol. 2018 Jun 15;221(Pt 12). pii: jeb179598. doi: 10.1242/jeb.179598.


International variation in programmes for assessment of children's neurodevelopment in the community: Understanding disparate approaches to evaluation of motor, social, emotional, behavioural and cognitive function.

Wilson P, Wood R, Lykke K, Hauskov Graungaard A, Ertmann RK, Andersen MK, Haavet OR, Lagerløv P, Abildsnes E, Dahli MP, Mäkelä M, Varinen A, Hietanen M.

Scand J Public Health. 2018 Dec;46(8):805-816. doi: 10.1177/1403494818772211. Epub 2018 May 4.


Long-Term Metastatic Risk after Biopsy of Posterior Uveal Melanoma.

Bagger M, Smidt-Nielsen I, Andersen MK, Jensen PK, Heegaard S, Andersen KK, Friis S, Kiilgaard JF.

Ophthalmology. 2018 Dec;125(12):1969-1976. doi: 10.1016/j.ophtha.2018.03.047. Epub 2018 Apr 25.


Cholesterol synthesis pathway genes in prostate cancer are transcriptionally downregulated when tissue confounding is minimized.

Rye MB, Bertilsson H, Andersen MK, Rise K, Bathen TF, Drabløs F, Tessem MB.

BMC Cancer. 2018 Apr 27;18(1):478. doi: 10.1186/s12885-018-4373-y.


Paralytic hypo-energetic state facilitates anoxia tolerance despite ionic imbalance in adult Drosophila melanogaster.

Campbell JB, Andersen MK, Overgaard J, Harrison JF.

J Exp Biol. 2018 Jun 14;221(Pt 12). pii: jeb177147. doi: 10.1242/jeb.177147.


Genetic architecture of obesity and related metabolic traits-recent insights from isolated populations.

Andersen MK, Grarup N, Moltke I, Albrechtsen A, Hansen T.

Curr Opin Genet Dev. 2018 Jun;50:74-78. doi: 10.1016/j.gde.2018.02.010. Epub 2018 Mar 3. Review.


Early relapsed disease of multiple myeloma following up-front HDM-ASCT: a study based on the Danish Multiple Myeloma Registry in the period 2005 to 2014.

Helm-Petersen S, Sørrig R, Klausen TW, Preiss B, Frølund UC, Helleberg C, Breinholt M, Andersen MK, Abildgaard N, Gimsing P, Vangsted AJ.

Leukemia. 2018 Sep;32(9):2054-2057. doi: 10.1038/s41375-018-0057-5. Epub 2018 Feb 22. No abstract available.


Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes.

Grarup N, Moltke I, Andersen MK, Dalby M, Vitting-Seerup K, Kern T, Mahendran Y, Jørsboe E, Larsen CVL, Dahl-Petersen IK, Gilly A, Suveges D, Dedoussis G, Zeggini E, Pedersen O, Andersson R, Bjerregaard P, Jørgensen ME, Albrechtsen A, Hansen T.

Nat Genet. 2018 Feb;50(2):172-174. doi: 10.1038/s41588-017-0022-7. Epub 2018 Jan 8.


How is defensive medicine understood and experienced in a primary care setting? A qualitative focus group study among Danish general practitioners.

Assing Hvidt E, Lykkegaard J, Pedersen LB, Pedersen KM, Munck A, Andersen MK.

BMJ Open. 2017 Dec 21;7(12):e019851. doi: 10.1136/bmjopen-2017-019851.


SFRP4 gene expression is increased in aggressive prostate cancer.

Sandsmark E, Andersen MK, Bofin AM, Bertilsson H, Drabløs F, Bathen TF, Rye MB, Tessem MB.

Sci Rep. 2017 Oct 27;7(1):14276. doi: 10.1038/s41598-017-14622-3.


Cold tolerance of Drosophila species is tightly linked to the epithelial K+ transport capacity of the Malpighian tubules and rectal pads.

Andersen MK, MacMillan HA, Donini A, Overgaard J.

J Exp Biol. 2017 Nov 15;220(Pt 22):4261-4269. doi: 10.1242/jeb.168518. Epub 2017 Sep 25.


TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy.

Eskelund CW, Dahl C, Hansen JW, Westman M, Kolstad A, Pedersen LB, Montano-Almendras CP, Husby S, Freiburghaus C, Ek S, Pedersen A, Niemann C, Räty R, Brown P, Geisler CH, Andersen MK, Guldberg P, Jerkeman M, Grønbæk K.

Blood. 2017 Oct 26;130(17):1903-1910. doi: 10.1182/blood-2017-04-779736. Epub 2017 Aug 17.


Bilateral diffuse uveal melanocytic proliferation: Case report and literature review.

Klemp K, Kiilgaard JF, Heegaard S, Nørgaard T, Andersen MK, Prause JU.

Acta Ophthalmol. 2017 Aug;95(5):439-445. doi: 10.1111/aos.13481. Epub 2017 Jun 21. Review.


Children with low-risk acute lymphoblastic leukemia are at highest risk of second cancers.

Nielsen SN, Eriksson F, Rosthoej S, Andersen MK, Forestier E, Hasle H, Hjalgrim LL, Aasberg A, Abrahamsson J, Heyman M, Jónsson ÓG, Pruunsild K, Vaitkeviciené GE, Vettenranta K, Schmiegelow K.

Pediatr Blood Cancer. 2017 Oct;64(10). doi: 10.1002/pbc.26518. Epub 2017 May 13.


General practitioners' attitudes towards and experiences with referrals due to supplemental health insurance.

Andersen MK, Pedersen LB, Dupont M, Pedersen KM, Munck A, Nexøe J.

Fam Pract. 2017 Sep 1;34(5):581-586. doi: 10.1093/fampra/cmx035.


Accreditation in general practice in Denmark: study protocol for a cluster-randomized controlled trial.

Andersen MK, Pedersen LB, Siersma V, Bro F, Reventlow S, Søndergaard J, Kousgaard MB, Waldorff FB.

Trials. 2017 Feb 13;18(1):69. doi: 10.1186/s13063-017-1818-6.


Physiological correlates of chill susceptibility in Lepidoptera.

Andersen MK, Jensen SO, Overgaard J.

J Insect Physiol. 2017 Apr;98:317-326. doi: 10.1016/j.jinsphys.2017.02.002. Epub 2017 Feb 8.


Frailty characteristics and preventive home visits: an audit on elderly patients in Danish general practice.

Christensen HK, Kristensen T, Andersen MK, Lykkegaard J.

Fam Pract. 2017 Feb;34(1):57-62. doi: 10.1093/fampra/cmw110. Epub 2016 Oct 17.


Cold acclimation improves chill tolerance in the migratory locust through preservation of ion balance and membrane potential.

Andersen MK, Folkersen R, MacMillan HA, Overgaard J.

J Exp Biol. 2017 Feb 1;220(Pt 3):487-496. doi: 10.1242/jeb.150813. Epub 2016 Nov 30.


Mutations in idiopathic cytopenia of undetermined significance assist diagnostics and correlate to dysplastic changes.

Hansen JW, Westman MK, Sjö LD, Saft L, Kristensen LS, Ørskov AD, Treppendahl M, Andersen MK, Grønbaek K.

Am J Hematol. 2016 Dec;91(12):1234-1238. doi: 10.1002/ajh.24554. Epub 2016 Nov 8.


Almost half of the Danish general practitioners have negative a priori attitudes towards a mandatory accreditation programme.

Waldorff FB, Nicolaisdóttir DR, Kousgaard MB, Reventlow S, Søndergaard J, Thorsen T, Andersen MK, Pedersen LB, Bisgaard L, Hutters CL, Bro F.

Dan Med J. 2016 Sep;63(9). pii: A5266.


Leukemic blasts are present at low levels in spinal fluid in one-third of childhood acute lymphoblastic leukemia cases.

Levinsen M, Marquart HV, Groth-Pedersen L, Abrahamsson J, Albertsen BK, Andersen MK, Frandsen TL, Harila-Saari A, Pronk C, Ulvmoen A, Vaitkevičienė G, Lähteenmäki PM, Niinimäki R, Taskinen M, Jeppesen M, Schmiegelow K; Nordic Society of Pediatric Hematology and Oncology (NOPHO).

Pediatr Blood Cancer. 2016 Nov;63(11):1935-42. doi: 10.1002/pbc.26128. Epub 2016 Jul 22.


Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders.

Andersen MK, Jørsboe E, Sandholt CH, Grarup N, Jørgensen ME, Færgeman NJ, Bjerregaard P, Pedersen O, Moltke I, Hansen T, Albrechtsen A.

PLoS Genet. 2016 Jun 24;12(6):e1006119. doi: 10.1371/journal.pgen.1006119. eCollection 2016 Jun.


Genetics of Type 2 Diabetes: the Power of Isolated Populations.

Andersen MK, Pedersen CE, Moltke I, Hansen T, Albrechtsen A, Grarup N.

Curr Diab Rep. 2016 Jul;16(7):65. doi: 10.1007/s11892-016-0757-z. Review.


Gene expression risk signatures maintain prognostic power in multiple myeloma despite microarray probe set translation.

Hermansen NE, Borup R, Andersen MK, Vangsted AJ, Clausen NT, Kristensen DL, Nielsen FC, Gimsing P.

Int J Lab Hematol. 2016 Jun;38(3):298-307. doi: 10.1111/ijlh.12486. Epub 2016 Mar 29.


Hypogammaglobulinemia in newly diagnosed chronic lymphocytic leukemia is a predictor of early death.

Andersen MA, Vojdeman FJ, Andersen MK, Brown Pde N, Geisler CH, Weis Bjerrum O, Niemann CU.

Leuk Lymphoma. 2016 Jul;57(7):1592-9. doi: 10.3109/10428194.2016.1142082. Epub 2016 Feb 5. Erratum in: Leuk Lymphoma. 2016 Jul;57(7):I.


Ambient CO2, fish behaviour and altered GABAergic neurotransmission: exploring the mechanism of CO2-altered behaviour by taking a hypercapnia dweller down to low CO2 levels.

Regan MD, Turko AJ, Heras J, Andersen MK, Lefevre S, Wang T, Bayley M, Brauner CJ, Huong do TT, Phuong NT, Nilsson GE.

J Exp Biol. 2016 Jan;219(Pt 1):109-18. doi: 10.1242/jeb.131375.


JP-HHT phenotype in Danish patients with SMAD4 mutations.

Jelsig AM, Tørring PM, Kjeldsen AD, Qvist N, Bojesen A, Jensen UB, Andersen MK, Gerdes AM, Brusgaard K, Ousager LB.

Clin Genet. 2016 Jul;90(1):55-62. doi: 10.1111/cge.12693. Epub 2015 Dec 21.


[Patients with spinal cord injuries experience many sequelae].

Lundberg AS, Andersen MK, Kasch H, Hansen RM.

Ugeskr Laeger. 2015 Oct 9;177(43):V06150476. Review. Danish.


Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients.

Helbo AS, Treppendahl M, Aslan D, Dimopoulos K, Nandrup-Bus C, Holm MS, Andersen MK, Liang G, Kristensen LS, Grønbæk K.

Genes (Basel). 2015 Oct 14;6(4):977-90. doi: 10.3390/genes6040977.


Transvitreal Retinochoroidal Biopsy Provides a Representative Sample From Choroidal Melanoma for Detection of Chromosome 3 Aberrations.

Bagger M, Andersen MT, Heegaard S, Andersen MK, Kiilgaard JF.

Invest Ophthalmol Vis Sci. 2015 Sep;56(10):5917-24. doi: 10.1167/iovs.15-17349.


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