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Items: 44


Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations.

Crombie TA, Zdraljevic S, Cook DE, Tanny RE, Brady SC, Wang Y, Evans KS, Hahnel S, Lee D, Rodriguez BC, Zhang G, van der Zwagg J, Kiontke K, Andersen EC.

Elife. 2019 Dec 3;8. pii: e50465. doi: 10.7554/eLife.50465. [Epub ahead of print]


Tightly linked antagonistic-effect loci underlie polygenic phenotypic variation in C. elegans.

Bernstein MR, Zdraljevic S, Andersen EC, Rockman MV.

Evol Lett. 2019 Sep 11;3(5):462-473. doi: 10.1002/evl3.139. eCollection 2019 Oct.


Selection and gene flow shape niche-associated variation in pheromone response.

Lee D, Zdraljevic S, Cook DE, Frézal L, Hsu JC, Sterken MG, Riksen JAG, Wang J, Kammenga JE, Braendle C, Félix MA, Schroeder FC, Andersen EC.

Nat Ecol Evol. 2019 Oct;3(10):1455-1463. doi: 10.1038/s41559-019-0982-3. Epub 2019 Sep 23.


Natural Variation and Genetic Determinants of Caenorhabditis elegans Sperm Size.

Gimond C, Vielle A, Silva-Soares N, Zdraljevic S, McGrath PT, Andersen EC, Braendle C.

Genetics. 2019 Oct;213(2):615-632. doi: 10.1534/genetics.119.302462. Epub 2019 Aug 8.


A Novel Gene Underlies Bleomycin-Response Variation in Caenorhabditis elegans.

Brady SC, Zdraljevic S, Bisaga KW, Tanny RE, Cook DE, Lee D, Wang Y, Andersen EC.

Genetics. 2019 Aug;212(4):1453-1468. doi: 10.1534/genetics.119.302286. Epub 2019 Jun 6.


Long-read sequencing reveals intra-species tolerance of substantial structural variations and new subtelomere formation in C. elegans.

Kim C, Kim J, Kim S, Cook DE, Evans KS, Andersen EC, Lee J.

Genome Res. 2019 Jun;29(6):1023-1035. doi: 10.1101/gr.246082.118. Epub 2019 May 23.


Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino acid metabolism.

Zdraljevic S, Fox BW, Strand C, Panda O, Tenjo FJ, Brady SC, Crombie TA, Doench JG, Schroeder FC, Andersen EC.

Elife. 2019 Apr 8;8. pii: e40260. doi: 10.7554/eLife.40260.


Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles.

Hahnel SR, Zdraljevic S, Rodriguez BC, Zhao Y, McGrath PT, Andersen EC.

PLoS Pathog. 2018 Oct 29;14(10):e1007226. doi: 10.1371/journal.ppat.1007226. eCollection 2018 Oct.


Shared Genomic Regions Underlie Natural Variation in Diverse Toxin Responses.

Evans KS, Brady SC, Bloom JS, Tanny RE, Cook DE, Giuliani SE, Hippleheuser SW, Zamanian M, Andersen EC.

Genetics. 2018 Dec;210(4):1509-1525. doi: 10.1534/genetics.118.301311. Epub 2018 Oct 19.


Discovery of genomic intervals that underlie nematode responses to benzimidazoles.

Zamanian M, Cook DE, Zdraljevic S, Brady SC, Lee D, Lee J, Andersen EC.

PLoS Negl Trop Dis. 2018 Mar 30;12(3):e0006368. doi: 10.1371/journal.pntd.0006368. eCollection 2018 Mar.


Natural diversity facilitates the discovery of conserved chemotherapeutic response mechanisms.

Zdraljevic S, Andersen EC.

Curr Opin Genet Dev. 2017 Dec;47:41-47. doi: 10.1016/j.gde.2017.08.002. Epub 2017 Sep 9. Review.


The genetic basis of natural variation in a phoretic behavior.

Lee D, Yang H, Kim J, Brady S, Zdraljevic S, Zamanian M, Kim H, Paik YK, Kruglyak L, Andersen EC, Lee J.

Nat Commun. 2017 Aug 17;8(1):273. doi: 10.1038/s41467-017-00386-x.


Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.

Zdraljevic S, Strand C, Seidel HS, Cook DE, Doench JG, Andersen EC.

PLoS Genet. 2017 Jul 12;13(7):e1006891. doi: 10.1371/journal.pgen.1006891. eCollection 2017 Jul.


Natural Variation in the Distribution and Abundance of Transposable Elements Across the Caenorhabditis elegans Species.

Laricchia KM, Zdraljevic S, Cook DE, Andersen EC.

Mol Biol Evol. 2017 Sep 1;34(9):2187-2202. doi: 10.1093/molbev/msx155.


Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics.

García-González AP, Ritter AD, Shrestha S, Andersen EC, Yilmaz LS, Walhout AJM.

Cell. 2017 Apr 20;169(3):431-441.e8. doi: 10.1016/j.cell.2017.03.046.


VCF-kit: assorted utilities for the variant call format.

Cook DE, Andersen EC.

Bioinformatics. 2017 May 15;33(10):1581-1582. doi: 10.1093/bioinformatics/btx011.


Copper Oxide Nanoparticles Impact Several Toxicological Endpoints and Cause Neurodegeneration in Caenorhabditis elegans.

Mashock MJ, Zanon T, Kappell AD, Petrella LN, Andersen EC, Hristova KR.

PLoS One. 2016 Dec 2;11(12):e0167613. doi: 10.1371/journal.pone.0167613. eCollection 2016.


Correlations of Genotype with Climate Parameters Suggest Caenorhabditis elegans Niche Adaptations.

Evans KS, Zhao Y, Brady SC, Long L, McGrath PT, Andersen EC.

G3 (Bethesda). 2017 Jan 5;7(1):289-298. doi: 10.1534/g3.116.035162.


CeNDR, the Caenorhabditis elegans natural diversity resource.

Cook DE, Zdraljevic S, Roberts JP, Andersen EC.

Nucleic Acids Res. 2017 Jan 4;45(D1):D650-D657. doi: 10.1093/nar/gkw893. Epub 2016 Oct 3.


Selection on a Subunit of the NURF Chromatin Remodeler Modifies Life History Traits in a Domesticated Strain of Caenorhabditis elegans.

Large EE, Xu W, Zhao Y, Brady SC, Long L, Butcher RA, Andersen EC, McGrath PT.

PLoS Genet. 2016 Jul 28;12(7):e1006219. doi: 10.1371/journal.pgen.1006219. eCollection 2016 Jul.


The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length.

Cook DE, Zdraljevic S, Tanny RE, Seo B, Riccardi DD, Noble LM, Rockman MV, Alkema MJ, Braendle C, Kammenga JE, Wang J, Kruglyak L, Félix MA, Lee J, Andersen EC.

Genetics. 2016 Sep;204(1):371-83. doi: 10.1534/genetics.116.191148. Epub 2016 Jul 22.


Mutation Is a Sufficient and Robust Predictor of Genetic Variation for Mitotic Spindle Traits in Caenorhabditis elegans.

Farhadifar R, Ponciano JM, Andersen EC, Needleman DJ, Baer CF.

Genetics. 2016 Aug;203(4):1859-70. doi: 10.1534/genetics.115.185736. Epub 2016 Jun 22.


Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector-borne nematode diseases.

Zamanian M, Andersen EC.

FEBS J. 2016 Sep;283(17):3204-21. doi: 10.1111/febs.13781. Epub 2016 Jul 11. Review.


Remarkably Divergent Regions Punctuate the Genome Assembly of the Caenorhabditis elegans Hawaiian Strain CB4856.

Thompson OA, Snoek LB, Nijveen H, Sterken MG, Volkers RJ, Brenchley R, Van't Hof A, Bevers RP, Cossins AR, Yanai I, Hajnal A, Schmid T, Perkins JD, Spencer D, Kruglyak L, Andersen EC, Moerman DG, Hillier LW, Kammenga JE, Waterston RH.

Genetics. 2015 Jul;200(3):975-89. doi: 10.1534/genetics.115.175950. Epub 2015 May 19.


The laboratory domestication of Caenorhabditis elegans.

Sterken MG, Snoek LB, Kammenga JE, Andersen EC.

Trends Genet. 2015 May;31(5):224-31. doi: 10.1016/j.tig.2015.02.009. Epub 2015 Mar 21. Review.


A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains.

Andersen EC, Shimko TC, Crissman JR, Ghosh R, Bloom JS, Seidel HS, Gerke JP, Kruglyak L.

G3 (Bethesda). 2015 Mar 13;5(5):911-20. doi: 10.1534/g3.115.017178.


Scaling, selection, and evolutionary dynamics of the mitotic spindle.

Farhadifar R, Baer CF, Valfort AC, Andersen EC, Müller-Reichert T, Delattre M, Needleman DJ.

Curr Biol. 2015 Mar 16;25(6):732-740. doi: 10.1016/j.cub.2014.12.060. Epub 2015 Feb 12.


A wild C. elegans strain has enhanced epithelial immunity to a natural microsporidian parasite.

Balla KM, Andersen EC, Kruglyak L, Troemel ER.

PLoS Pathog. 2015 Feb 13;11(2):e1004583. doi: 10.1371/journal.ppat.1004583. eCollection 2015 Feb.


The red death meets the abdominal bristle: polygenic mutation for susceptibility to a bacterial pathogen in Caenorhabditis elegans.

Etienne V, Andersen EC, Ponciano JM, Blanton D, Cadavid A, Joyner-Matos J, Matsuba C, Tabman B, Baer CF.

Evolution. 2015 Feb;69(2):508-19. doi: 10.1111/evo.12585. Epub 2015 Jan 19.


COPASutils: an R package for reading, processing, and visualizing data from COPAS large-particle flow cytometers.

Shimko TC, Andersen EC.

PLoS One. 2014 Oct 20;9(10):e111090. doi: 10.1371/journal.pone.0111090. eCollection 2014.


A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology.

Andersen EC, Bloom JS, Gerke JP, Kruglyak L.

PLoS Genet. 2014 Feb 27;10(2):e1004156. doi: 10.1371/journal.pgen.1004156. eCollection 2014 Feb. Erratum in: PLoS Genet. 2014 Mar;10(3):e1004316.


Species richness, distribution and genetic diversity of Caenorhabditis nematodes in a remote tropical rainforest.

Félix MA, Jovelin R, Ferrari C, Han S, Cho YR, Andersen EC, Cutter AD, Braendle C.

BMC Evol Biol. 2013 Jan 12;13:10. doi: 10.1186/1471-2148-13-10.


Natural variation in a chloride channel subunit confers avermectin resistance in C. elegans.

Ghosh R, Andersen EC, Shapiro JA, Gerke JP, Kruglyak L.

Science. 2012 Feb 3;335(6068):574-8. doi: 10.1126/science.1214318.


Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity.

Andersen EC, Gerke JP, Shapiro JA, Crissman JR, Ghosh R, Bloom JS, Félix MA, Kruglyak L.

Nat Genet. 2012 Jan 29;44(3):285-90. doi: 10.1038/ng.1050.


PCR-directed in vivo plasmid construction using homologous recombination in baker's yeast.

Andersen EC.

Methods Mol Biol. 2011;772:409-21. doi: 10.1007/978-1-61779-228-1_24.


Differential localization and independent acquisition of the H3K9me2 and H3K9me3 chromatin modifications in the Caenorhabditis elegans adult germ line.

Bessler JB, Andersen EC, Villeneuve AM.

PLoS Genet. 2010 Jan 22;6(1):e1000830. doi: 10.1371/journal.pgen.1000830.


Deregulation of apoptotic volume decrease and ionic movements in multidrug-resistant tumor cells: role of chloride channels.

Poulsen KA, Andersen EC, Hansen CF, Klausen TK, Hougaard C, Lambert IH, Hoffmann EK.

Am J Physiol Cell Physiol. 2010 Jan;298(1):C14-25. doi: 10.1152/ajpcell.00654.2008. Epub 2009 Oct 21.


A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans.

Reddy KC, Andersen EC, Kruglyak L, Kim DH.

Science. 2009 Jan 16;323(5912):382-4. doi: 10.1126/science.1166527.


Multiple levels of redundant processes inhibit Caenorhabditis elegans vulval cell fates.

Andersen EC, Saffer AM, Horvitz HR.

Genetics. 2008 Aug;179(4):2001-12. doi: 10.1534/genetics.108.092197. Epub 2008 Aug 9.


Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development.

Andersen EC, Horvitz HR.

Development. 2007 Aug;134(16):2991-9. Epub 2007 Jul 18.


DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans.

Reddien PW, Andersen EC, Huang MC, Horvitz HR.

Genetics. 2007 Apr;175(4):1719-33. Epub 2007 Jan 21.


C. elegans ISWI and NURF301 antagonize an Rb-like pathway in the determination of multiple cell fates.

Andersen EC, Lu X, Horvitz HR.

Development. 2006 Jul;133(14):2695-704. Epub 2006 Jun 14.


Patterns of gene expression during Drosophila mesoderm development.

Furlong EE, Andersen EC, Null B, White KP, Scott MP.

Science. 2001 Aug 31;293(5535):1629-33. Epub 2001 Aug 2.


Electrostatic control of enzyme reactions: the mechanism of inhibition of glucose oxidase by putrescine.

Voet JG, Andersen EC.

Arch Biochem Biophys. 1984 Aug 15;233(1):88-92.


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