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Items: 1 to 50 of 70

1.

Thy-1 (CD90) promotes bone formation and protects against obesity.

Picke AK, Campbell GM, Blüher M, Krügel U, Schmidt FN, Tsourdi E, Winzer M, Rauner M, Vukicevic V, Busse B, Salbach-Hirsch J, Tuckermann JP, Simon JC, Anderegg U, Hofbauer LC, Saalbach A.

Sci Transl Med. 2018 Aug 8;10(453). pii: eaao6806. doi: 10.1126/scitranslmed.aao6806.

PMID:
30089635
2.

High-Fat Diet Exacerbates Early Psoriatic Skin Inflammation Independent of Obesity: Saturated Fatty Acids as Key Players.

Herbert D, Franz S, Popkova Y, Anderegg U, Schiller J, Schwede K, Lorz A, Simon JC, Saalbach A.

J Invest Dermatol. 2018 Mar 30. pii: S0022-202X(18)31858-X. doi: 10.1016/j.jid.2018.03.1522. [Epub ahead of print]

PMID:
29605673
3.

Mimicking Paracrine TGFβ1 Signals during Myofibroblast Differentiation in 3D Collagen Networks.

Ansorge M, Sapudom J, Chkolnikov M, Wilde M, Anderegg U, Möller S, Schnabelrauch M, Pompe T.

Sci Rep. 2017 Jul 18;7(1):5664. doi: 10.1038/s41598-017-05912-x.

4.

Fibroblast fate regulation by time dependent TGF-β1 and IL-10 stimulation in biomimetic 3D matrices.

Sapudom J, Wu X, Chkolnikov M, Ansorge M, Anderegg U, Pompe T.

Biomater Sci. 2017 Aug 22;5(9):1858-1867. doi: 10.1039/c7bm00286f.

PMID:
28676875
5.

Molecular weight specific impact of soluble and immobilized hyaluronan on CD44 expressing melanoma cells in 3D collagen matrices.

Sapudom J, Ullm F, Martin S, Kalbitzer L, Naab J, Möller S, Schnabelrauch M, Anderegg U, Schmidt S, Pompe T.

Acta Biomater. 2017 Mar 1;50:259-270. doi: 10.1016/j.actbio.2016.12.026. Epub 2016 Dec 10.

PMID:
27965172
6.

Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq.

Gerber T, Willscher E, Loeffler-Wirth H, Hopp L, Schadendorf D, Schartl M, Anderegg U, Camp G, Treutlein B, Binder H, Kunz M.

Oncotarget. 2017 Jan 3;8(1):846-862. doi: 10.18632/oncotarget.13666.

7.

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.

Riecken LB, Zoch A, Wiehl U, Reichert S, Scholl I, Cui Y, Ziemer M, Anderegg U, Hagel C, Morrison H.

Oncotarget. 2016 Nov 29;7(48):78242-78254. doi: 10.18632/oncotarget.12919.

8.

New E-beam-initiated hyaluronan acrylate cryogels support growth and matrix deposition by dermal fibroblasts.

Thönes S, Kutz LM, Oehmichen S, Becher J, Heymann K, Saalbach A, Knolle W, Schnabelrauch M, Reichelt S, Anderegg U.

Int J Biol Macromol. 2017 Jan;94(Pt A):611-620. doi: 10.1016/j.ijbiomac.2016.10.065. Epub 2016 Oct 20.

PMID:
27773837
9.

Thy-1/β3 Integrin Interaction-Induced Apoptosis of Dermal Fibroblasts Is Mediated by Up-Regulation of FasL Expression.

Schmidt M, Gutknecht D, Anastassiadis K, Eckes B, Anderegg U, Saalbach A.

J Invest Dermatol. 2016 Feb;136(2):526-9. doi: 10.1016/j.jid.2015.10.063. Epub 2015 Nov 18. No abstract available.

10.

Anti-Inflammatory Action of Keratinocyte-Derived Vaspin: Relevance for the Pathogenesis of Psoriasis.

Saalbach A, Tremel J, Herbert D, Schwede K, Wandel E, Schirmer C, Anderegg U, Beck-Sickinger AG, Heiker JT, Schultz S, Magin T, Simon JC.

Am J Pathol. 2016 Mar;186(3):639-51. doi: 10.1016/j.ajpath.2015.10.030. Epub 2016 Jan 11.

PMID:
26783881
11.

Glycosaminoglycan derivatives: promising candidates for the design of functional biomaterials.

Scharnweber D, Hübner L, Rother S, Hempel U, Anderegg U, Samsonov SA, Pisabarro MT, Hofbauer L, Schnabelrauch M, Franz S, Simon J, Hintze V.

J Mater Sci Mater Med. 2015 Sep;26(9):232. doi: 10.1007/s10856-015-5563-7. Epub 2015 Sep 10.

PMID:
26358319
12.

The interplay of fibronectin functionalization and TGF-β1 presence on fibroblast proliferation, differentiation and migration in 3D matrices.

Sapudom J, Rubner S, Martin S, Thoenes S, Anderegg U, Pompe T.

Biomater Sci. 2015 Sep;3(9):1291-301. doi: 10.1039/c5bm00140d.

PMID:
26230292
13.

TGFβ functionalized starPEG-heparin hydrogels modulate human dermal fibroblast growth and differentiation.

Watarai A, Schirmer L, Thönes S, Freudenberg U, Werner C, Simon JC, Anderegg U.

Acta Biomater. 2015 Oct;25:65-75. doi: 10.1016/j.actbio.2015.07.036. Epub 2015 Jul 26.

PMID:
26219861
14.

Artificial extracellular matrices support cell growth and matrix synthesis of human dermal fibroblasts in macroporous 3D scaffolds.

van der Smissen A, Hoffmeister PG, Friedrich N, Watarai A, Hacker MC, Schulz-Siegmund M, Anderegg U.

J Tissue Eng Regen Med. 2017 May;11(5):1390-1402. doi: 10.1002/term.2037. Epub 2015 May 26.

PMID:
26010761
15.

Fibroblasts support migration of monocyte-derived dendritic cells by secretion of PGE2 and MMP-1.

Saalbach A, Janik T, Busch M, Herbert D, Anderegg U, Simon JC.

Exp Dermatol. 2015 Aug;24(8):598-604. doi: 10.1111/exd.12722. Epub 2015 May 22.

PMID:
25865800
16.

Controlling the Balance of Fibroblast Proliferation and Differentiation: Impact of Thy-1.

Schmidt M, Gutknecht D, Simon JC, Schulz JN, Eckes B, Anderegg U, Saalbach A.

J Invest Dermatol. 2015 Jul;135(7):1893-1902. doi: 10.1038/jid.2015.86. Epub 2015 Mar 4.

17.

miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy.

Bhattacharya A, Schmitz U, Raatz Y, Schönherr M, Kottek T, Schauer M, Franz S, Saalbach A, Anderegg U, Wolkenhauer O, Schadendorf D, Simon JC, Magin T, Vera J, Kunz M.

Oncotarget. 2015 Feb 20;6(5):2966-80.

18.

Gelatin-based biomaterial engineering with anhydride-containing oligomeric cross-linkers.

Loth T, Hötzel R, Kascholke C, Anderegg U, Schulz-Siegmund M, Hacker MC.

Biomacromolecules. 2014 Jun 9;15(6):2104-18. doi: 10.1021/bm500241y. Epub 2014 May 21.

PMID:
24806218
19.

More than just a filler - the role of hyaluronan for skin homeostasis.

Anderegg U, Simon JC, Averbeck M.

Exp Dermatol. 2014 May;23(5):295-303. doi: 10.1111/exd.12370. Review.

PMID:
24628940
20.

Topologically defined composites of collagen types I and V as in vitro cell culture scaffolds.

Franke K, Sapudom J, Kalbitzer L, Anderegg U, Pompe T.

Acta Biomater. 2014 Jun;10(6):2693-702. doi: 10.1016/j.actbio.2014.02.036. Epub 2014 Mar 1.

PMID:
24590159
21.

Artificial extracellular matrix composed of collagen I and highly sulfated hyaluronan interferes with TGFβ(1) signaling and prevents TGFβ(1)-induced myofibroblast differentiation.

van der Smissen A, Samsonov S, Hintze V, Scharnweber D, Moeller S, Schnabelrauch M, Pisabarro MT, Anderegg U.

Acta Biomater. 2013 Aug;9(8):7775-86. doi: 10.1016/j.actbio.2013.04.023. Epub 2013 Apr 18.

PMID:
23602877
22.

Melanoma cells use Thy-1 (CD90) on endothelial cells for metastasis formation.

Schubert K, Gutknecht D, Köberle M, Anderegg U, Saalbach A.

Am J Pathol. 2013 Jan;182(1):266-76. doi: 10.1016/j.ajpath.2012.10.003. Epub 2012 Nov 16.

PMID:
23159525
23.

Quantitative proteomics reveals altered expression of extracellular matrix related proteins of human primary dermal fibroblasts in response to sulfated hyaluronan and collagen applied as artificial extracellular matrix.

Müller SA, van der Smissen A, von Feilitzsch M, Anderegg U, Kalkhof S, von Bergen M.

J Mater Sci Mater Med. 2012 Dec;23(12):3053-65. doi: 10.1007/s10856-012-4760-x. Epub 2012 Sep 19.

24.

Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action.

Schaab M, Kausch H, Klammt J, Nowicki M, Anderegg U, Gebhardt R, Rose-John S, Scheller J, Thiery J, Kratzsch J.

PLoS One. 2012;7(4):e34787. doi: 10.1371/journal.pone.0034787. Epub 2012 Apr 24.

25.

Vaspin--a link of obesity and psoriasis?

Saalbach A, Vester K, Rall K, Tremel J, Anderegg U, Beck-Sickinger AG, Blüher M, Simon JC.

Exp Dermatol. 2012 Apr;21(4):309-12. doi: 10.1111/j.1600-0625.2012.01460.x.

PMID:
22417310
26.

Regenerative potential of glycosaminoglycans for skin and bone.

Salbach J, Rachner TD, Rauner M, Hempel U, Anderegg U, Franz S, Simon JC, Hofbauer LC.

J Mol Med (Berl). 2012 Jun;90(6):625-35. doi: 10.1007/s00109-011-0843-2. Epub 2011 Dec 21. Review.

PMID:
22187113
27.

De novo biosynthesis of glycosaminoglycans in the extracellular matrix of skin studied by matrix-assisted laser desorption/ionization mass spectrometry.

Böhme J, Anderegg U, Nimptsch A, Nimptsch K, Hacker M, Schulz-Siegmund M, Huster D, Schiller J.

Anal Biochem. 2012 Feb 15;421(2):791-3. doi: 10.1016/j.ab.2011.11.002. Epub 2011 Nov 12.

PMID:
22138347
28.

Melanoma cells control HA synthesis in peritumoral fibroblasts via PDGF-AA and PDGF-CC: impact on melanoma cell proliferation.

Willenberg A, Saalbach A, Simon JC, Anderegg U.

J Invest Dermatol. 2012 Feb;132(2):385-93. doi: 10.1038/jid.2011.325. Epub 2011 Oct 13.

29.

Growth promoting substrates for human dermal fibroblasts provided by artificial extracellular matrices composed of collagen I and sulfated glycosaminoglycans.

van der Smissen A, Hintze V, Scharnweber D, Moeller S, Schnabelrauch M, Majok A, Simon JC, Anderegg U.

Biomaterials. 2011 Dec;32(34):8938-46. doi: 10.1016/j.biomaterials.2011.08.025. Epub 2011 Aug 27.

PMID:
21875749
30.

Influence of low dose irradiation on differentiation, maturation and T-cell activation of human dendritic cells.

Jahns J, Anderegg U, Saalbach A, Rosin B, Patties I, Glasow A, Kamprad M, Scholz M, Hildebrandt G.

Mutat Res. 2011 May 10;709-710:32-9. doi: 10.1016/j.mrfmmm.2011.02.007. Epub 2011 Mar 3.

PMID:
21376737
31.

Thy-1 (CD90) regulates the extravasation of leukocytes during inflammation.

Schubert K, Polte T, Bönisch U, Schader S, Holtappels R, Hildebrandt G, Lehmann J, Simon JC, Anderegg U, Saalbach A.

Eur J Immunol. 2011 Mar;41(3):645-56. doi: 10.1002/eji.201041117. Epub 2011 Jan 25.

32.

Suppression of hyaluronan synthase 2 expression reflects the atrophogenic potential of glucocorticoids.

Averbeck M, Gebhardt C, Anderegg U, Simon JC.

Exp Dermatol. 2010 Aug;19(8):757-9. doi: 10.1111/j.1600-0625.2010.01099.x.

PMID:
20659158
33.

Connective tissue response to fractionated thermo-ablative Erbium: YAG skin laser treatment.

Bodendorf MO, Willenberg A, Anderegg U, Grunewald S, Simon JC, Paasch U.

Int J Cosmet Sci. 2010 Dec;32(6):435-45. doi: 10.1111/j.1468-2494.2009.00567.x.

PMID:
20384901
34.

Elevated sex steroid hormones in great saphenous veins in men.

Kendler M, Makrantonaki E, Tzellos T, Kratzsch J, Anderegg U, Wetzig T, Zouboulis C, Simon JC.

J Vasc Surg. 2010 Mar;51(3):639-46. doi: 10.1016/j.jvs.2009.07.128. Epub 2010 Jan 4. Erratum in: J Vasc Surg. 2010 Aug;52(2):538. Tzellos, Thrasivoulos [added].

35.

Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions.

Schiller M, Dennler S, Anderegg U, Kokot A, Simon JC, Luger TA, Mauviel A, Böhm M.

J Biol Chem. 2010 Jan 1;285(1):409-21. doi: 10.1074/jbc.M109.038620. Epub 2009 Oct 26.

36.

The NF-kappaB signalling pathway is involved in the LPS/IL-2-induced upregulation of FoxP3 expression in human CD4+CD25high regulatory T cells.

Milkova L, Voelcker V, Forstreuter I, Sack U, Anderegg U, Simon JC, Maier-Simon C.

Exp Dermatol. 2010 Jan;19(1):29-37. doi: 10.1111/j.1600-0625.2009.00953.x. Epub 2009 Oct 21.

PMID:
19845758
37.

Dermal fibroblasts promote the migration of dendritic cells.

Saalbach A, Klein C, Schirmer C, Briest W, Anderegg U, Simon JC.

J Invest Dermatol. 2010 Feb;130(2):444-54. doi: 10.1038/jid.2009.253. Epub 2009 Aug 27.

38.

Dermal hyaluronan is rapidly reduced by topical treatment with glucocorticoids.

Gebhardt C, Averbeck M, Diedenhofen N, Willenberg A, Anderegg U, Sleeman JP, Simon JC.

J Invest Dermatol. 2010 Jan;130(1):141-9. doi: 10.1038/jid.2009.210.

39.

ADAM10 is the constitutive functional sheddase of CD44 in human melanoma cells.

Anderegg U, Eichenberg T, Parthaune T, Haiduk C, Saalbach A, Milkova L, Ludwig A, Grosche J, Averbeck M, Gebhardt C, Voelcker V, Sleeman JP, Simon JC.

J Invest Dermatol. 2009 Jun;129(6):1471-82. doi: 10.1038/jid.2008.323. Epub 2008 Oct 30.

40.

Human Thy-1 induces secretion of matrix metalloproteinase-9 and CXCL8 from human neutrophils.

Saalbach A, Arnhold J, Lessig J, Simon JC, Anderegg U.

Eur J Immunol. 2008 May;38(5):1391-403. doi: 10.1002/eji.200737901.

41.

Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models.

Kloss D, Kurz R, Jahnke HG, Fischer M, Rothermel A, Anderegg U, Simon JC, Robitzki AA.

Biosens Bioelectron. 2008 May 15;23(10):1473-80. doi: 10.1016/j.bios.2008.01.003. Epub 2008 Jan 12.

PMID:
18289841
42.

Hyaluronan fragments induce cytokine and metalloprotease upregulation in human melanoma cells in part by signalling via TLR4.

Voelcker V, Gebhardt C, Averbeck M, Saalbach A, Wolf V, Weih F, Sleeman J, Anderegg U, Simon J.

Exp Dermatol. 2008 Feb;17(2):100-7. Epub 2007 Nov 21.

PMID:
18031543
43.

Ultraviolet-B irradiation enhances melanoma cell motility via induction of autocrine interleukin 8 secretion.

Gebhardt C, Averbeck M, Viertel A, Kauer F, Saalbach A, Anderegg U, Simon JC.

Exp Dermatol. 2007 Aug;16(8):636-43.

PMID:
17620090
44.

Switch in syndecan-1 and syndecan-4 expression controls maturation associated dendritic cell motility.

Averbeck M, Gebhardt C, Anderegg U, Termeer C, Sleeman JP, Simon JC.

Exp Dermatol. 2007 Jul;16(7):580-9.

PMID:
17576238
45.

Dermal fibroblasts induce maturation of dendritic cells.

Saalbach A, Klein C, Sleeman J, Sack U, Kauer F, Gebhardt C, Averbeck M, Anderegg U, Simon JC.

J Immunol. 2007 Apr 15;178(8):4966-74.

46.

Differential regulation of hyaluronan metabolism in the epidermal and dermal compartments of human skin by UVB irradiation.

Averbeck M, Gebhardt CA, Voigt S, Beilharz S, Anderegg U, Termeer CC, Sleeman JP, Simon JC.

J Invest Dermatol. 2007 Mar;127(3):687-97. Epub 2006 Nov 2.

47.

The signal-to-noise ratio as a measure of HA oligomer concentration: a MALDI-TOF MS study.

Busse K, Averbeck M, Anderegg U, Arnold K, Simon JC, Schiller J.

Carbohydr Res. 2006 Jun 12;341(8):1065-70. Epub 2006 Apr 11.

PMID:
16584713
48.

Increased neutrophil adherence in psoriasis: role of the human endothelial cell receptor Thy-1 (CD90).

Wetzel A, Wetzig T, Haustein UF, Sticherling M, Anderegg U, Simon JC, Saalbach A.

J Invest Dermatol. 2006 Feb;126(2):441-52.

49.

Investigation of arthritic joint destruction by a novel fibroblast-based model.

Sack U, Sehm B, Kahlenberg F, Murr A, Lehmann J, Tannapfel A, Uberla K, Moessner A, Dietrich A, Emmrich F, Lange F, Jungel A, Braun JM, Anderegg U.

Ann N Y Acad Sci. 2005 Jun;1051:291-8.

PMID:
16126970
50.

MEL4B3, a novel mRNA is induced in skin tumors and regulated by TGF-beta and pro-inflammatory cytokines.

Anderegg U, Breitschwerdt K, Köhler MJ, Sticherling M, Haustein UF, Simon JC, Saalbach A.

Exp Dermatol. 2005 Sep;14(9):709-18.

PMID:
16098131

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