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Frailty and Risk of Fractures in Patients With Type 2 Diabetes.

Li G, Prior JC, Leslie WD, Thabane L, Papaioannou A, Josse RG, Kaiser SM, Kovacs CS, Anastassiades T, Towheed T, Davison KS, Levine M, Goltzman D, Adachi JD; CaMos Research Group.

Diabetes Care. 2019 Jan 28. pii: dc181965. doi: 10.2337/dc18-1965. [Epub ahead of print]


A novel quantitative approach to the measurement of abdominal aortic calcification as applied to the Canadian Multicenter Osteoporosis Study (CaMOS).

Grant M, Turner ME, Murray-Guenther J, Anastassiades T, Hopman WM, Adams SM, Jeronimo P, Nolan R, Adams MA, Holden RM.

Bone. 2017 Apr;97:201-208. doi: 10.1016/j.bone.2017.01.018. Epub 2017 Jan 19.


Rheological study of hyaluronic acid derivatives.

Chernos M, Grecov D, Kwok E, Bebe S, Babsola O, Anastassiades T.

Biomed Eng Lett. 2017 Jan 17;7(1):17-24. doi: 10.1007/s13534-017-0010-y. eCollection 2017 Feb.


Human acetyl-CoA:glucosamine-6-phosphate N-acetyltransferase 1 has a relaxed donor specificity and transfers acyl groups up to four carbons in length.

Brockhausen I, Nair DG, Chen M, Yang X, Allingham JS, Szarek WA, Anastassiades T.

Biochem Cell Biol. 2016 Apr;94(2):197-204. doi: 10.1139/bcb-2015-0115. Epub 2015 Dec 15.


Ten-year incident osteoporosis-related fractures in the population-based Canadian Multicentre Osteoporosis Study - comparing site and age-specific risks in women and men.

Prior JC, Langsetmo L, Lentle BC, Berger C, Goltzman D, Kovacs CS, Kaiser SM, Adachi JD, Papaioannou A, Anastassiades T, Towheed T, Josse RG, Brown JP, Leslie WD, Kreiger N; CaMOS Research Group.

Bone. 2015 Feb;71:237-43. doi: 10.1016/j.bone.2014.10.026. Epub 2014 Nov 7.


Chemically modified N-acylated hyaluronan fragments modulate proinflammatory cytokine production by stimulated human macrophages.

Babasola O, Rees-Milton KJ, Bebe S, Wang J, Anastassiades TP.

J Biol Chem. 2014 Sep 5;289(36):24779-91. doi: 10.1074/jbc.M113.515783. Epub 2014 Jul 22.


Prospectively measured 10-year changes in health-related quality of life and comparison with cross-sectional estimates in a population-based cohort of adult women and men.

Hopman WM, Berger C, Joseph L, Zhou W, Prior JC, Towheed T, Anastassiades T, Adachi JD, Hanley DA, Papadimitropoulos EA, Kirkland S, Kaiser SM, Josse RG, Goltzman D; CaMos Research Group.

Qual Life Res. 2014 Dec;23(10):2707-21. doi: 10.1007/s11136-014-0733-5. Epub 2014 Jun 13.


Effect of Anticholinergic Medications on Falls, Fracture Risk, and Bone Mineral Density Over a 10-Year Period.

Fraser LA, Adachi JD, Leslie WD, Goltzman D, Josse R, Prior J, Kaiser S, Kreiger N, Kovacs CS, Anastassiades TP, Papaioannou A; for the CaMos Research Group.

Ann Pharmacother. 2014 Aug;48(8):954-961. Epub 2014 May 9.


Choice of lumbar spine bone density reference database for fracture prediction in men and women: a population-based analysis.

Leslie WD, Langsetmo L, Zhou W, Goltzman D, Kovacs CS, Prior J, Josse R, Olszynski WP, Davison KS, Anastassiades T, Towheed T, Hanley DA, Kaiser SM, Lentle B, Kreiger N; CaMos Research Group.

J Clin Densitom. 2014 Apr-Jun;17(2):295-300. doi: 10.1016/j.jocd.2013.09.003. Epub 2014 Mar 7.


Longitudinal changes in calcium and vitamin D intakes and relationship to bone mineral density in a prospective population-based study: the Canadian Multicentre Osteoporosis Study (CaMos).

Zhou W, Langsetmo L, Berger C, Poliquin S, Kreiger N, Barr SI, Kaiser SM, Josse RG, Prior JC, Towheed TE, Anastassiades T, Davison KS, Kovacs CS, Hanley DA, Papadimitropoulos EA, Goltzman D; CaMos Research Group.

J Musculoskelet Neuronal Interact. 2013 Dec;13(4):470-9.


N-acylated glucosamines for bone and joint disorders: effects of N-butyryl glucosamine on ovariectomized rat bone.

Anastassiades T, Rees-Milton K, Xiao H, Yang X, Willett T, Grynpas M.

Transl Res. 2013 Aug;162(2):93-101. doi: 10.1016/j.trsl.2013.04.002. Epub 2013 May 13.


The effect of glucosamine on glucose metabolism in humans: a systematic review of the literature.

Dostrovsky NR, Towheed TE, Hudson RW, Anastassiades TP.

Osteoarthritis Cartilage. 2011 Apr;19(4):375-80. doi: 10.1016/j.joca.2011.01.007. Epub 2011 Jan 18. Review.


Dietary patterns and incident low-trauma fractures in postmenopausal women and men aged ≥ 50 y: a population-based cohort study.

Langsetmo L, Hanley DA, Prior JC, Barr SI, Anastassiades T, Towheed T, Goltzman D, Morin S, Poliquin S, Kreiger N; CaMos Research Group.

Am J Clin Nutr. 2011 Jan;93(1):192-9. doi: 10.3945/ajcn.110.002956. Epub 2010 Nov 10.


Fragility fractures and the osteoporosis care gap in women: the Canadian Multicentre Osteoporosis Study.

Fraser LA, Ioannidis G, Adachi JD, Pickard L, Kaiser SM, Prior J, Brown JP, Hanley DA, Olszynski WP, Anastassiades T, Jamal S, Josse R, Goltzman D, Papaioannou A; CaMos Research Group.

Osteoporos Int. 2011 Mar;22(3):789-96. doi: 10.1007/s00198-010-1359-2. Epub 2010 Aug 4.


Using the same bone density reference database for men and women provides a simpler estimation of fracture risk.

Langsetmo L, Leslie WD, Zhou W, Goltzman D, Kovacs CS, Prior J, Josse R, Olszynski WP, Davison KS, Anastassiades T, Towheed T, Hanley DA, Kaiser S, Kreiger N; CaMOS Research Group.

J Bone Miner Res. 2010 Oct;25(10):2108-14. doi: 10.1002/jbmr.112.


Health-related quality of life in Canadian adolescents and young adults: normative data using the SF-36.

Hopman WM, Berger C, Joseph L, Towheed T, Prior JC, Anastassiades T, Poliquin S, Zhou W, Adachi JD, Hanley DA, Papadimitropoulos EA, Tenenhouse A; CaMos Research Group.

Can J Public Health. 2009 Nov-Dec;100(6):449-52.


Dietary patterns in Canadian men and women ages 25 and older: relationship to demographics, body mass index, and bone mineral density.

Langsetmo L, Poliquin S, Hanley DA, Prior JC, Barr S, Anastassiades T, Towheed T, Goltzman D, Kreiger N; CaMos Research Group.

BMC Musculoskelet Disord. 2010 Jan 28;11:20. doi: 10.1186/1471-2474-11-20.


Philip Hench, a Nobel link in the evolution of the Canada Gairdner International Awards.

Gordon DA, Anastassiades T.

J Rheumatol. 2010 Jan;37(1):195-8. doi: 10.3899/jrheum.091047. No abstract available.


Immunoassay of low to moderately abundant anionic proteins utilizing selective immobilization to chitosan-coated plates.

Rees-Milton KJ, Anastassiades TP.

Anal Biochem. 2010 Jan 15;396(2):310-2. doi: 10.1016/j.ab.2009.09.037. Epub 2009 Sep 24.


Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study.

Ioannidis G, Papaioannou A, Hopman WM, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS, Goltzman D, Thabane L, Gafni A, Papadimitropoulos EA, Brown JP, Josse RG, Hanley DA, Adachi JD.

CMAJ. 2009 Sep 1;181(5):265-71. doi: 10.1503/cmaj.081720. Epub 2009 Aug 4.


The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study.

Papaioannou A, Kennedy CC, Ioannidis G, Sawka A, Hopman WM, Pickard L, Brown JP, Josse RG, Kaiser S, Anastassiades T, Goltzman D, Papadimitropoulos M, Tenenhouse A, Prior JC, Olszynski WP, Adachi JD; CaMos Study Group.

Osteoporos Int. 2009 May;20(5):703-14. doi: 10.1007/s00198-008-0743-7. Epub 2008 Sep 19.


Geographic variation of bone mineral density and selected risk factors for prediction of incident fracture among Canadians 50 and older.

Langsetmo L, Hanley DA, Kreiger N, Jamal SA, Prior J, Adachi JD, Davison KS, Kovacs C, Anastassiades T, Tenenhouse A, Goltzman D; CaMos Research Group.

Bone. 2008 Oct;43(4):672-8. doi: 10.1016/j.bone.2008.06.009. Epub 2008 Jul 1.


A multifaceted intervention to improve treatment of osteoporosis in postmenopausal women with wrist fractures: a cluster randomized trial.

Cranney A, Lam M, Ruhland L, Brison R, Godwin M, Harrison MM, Harrison MB, Anastassiades T, Grimshaw JM, Graham ID.

Osteoporos Int. 2008 Dec;19(12):1733-40. doi: 10.1007/s00198-008-0669-0. Epub 2008 Jul 16.


Inflammation and arthritis: perspectives of the glycobiologist.

Brockhausen I, Anastassiades TP.

Expert Rev Clin Immunol. 2008 Mar;4(2):173-91. doi: 10.1586/1744666X.4.2.173.


The association between body mass index and health-related quality of life: data from CaMos, a stratified population study.

Hopman WM, Berger C, Joseph L, Barr SI, Gao Y, Prior JC, Poliquin S, Towheed T, Anastassiades T; CaMos Research Group.

Qual Life Res. 2007 Dec;16(10):1595-603. Epub 2007 Oct 24.


The osteoporosis care gap in men with fragility fractures: the Canadian Multicentre Osteoporosis Study.

Papaioannou A, Kennedy CC, Ioannidis G, Gao Y, Sawka AM, Goltzman D, Tenenhouse A, Pickard L, Olszynski WP, Davison KS, Kaiser S, Josse RG, Kreiger N, Hanley DA, Prior JC, Brown JP, Anastassiades T, Adachi JD; CaMos Research Group.

Osteoporos Int. 2008 Apr;19(4):581-7. Epub 2007 Oct 9.


Glucosamine therapy for osteoarthritis: an update.

Towheed TE, Anastassiades T.

J Rheumatol. 2007 Sep;34(9):1787-90. No abstract available.


Changes in body mass index in Canadians over a five-year period: results of a prospective, population-based study.

Hopman WM, Leroux C, Berger C, Joseph L, Barr SI, Prior JC, Harrison M, Poliquin S, Towheed T, Anastassiades T, Goltzman D; CaMos Research Group.

BMC Public Health. 2007 Jul 9;7:150.


Disease modifying effects of N-butyryl glucosamine in a streptococcal cell wall induced arthritis model in rats.

Wang SX, Cherian A, Dumitriu M, Grynpas MD, Carran J, Wainman D, Anastassiades T.

J Rheumatol. 2007 Apr;34(4):712-20. Epub 2007 Feb 15.


Single dose pharmacokinetics and bioavailability of butyryl glucosamine in the rat.

Aghazadeh-Habashi A, Ibrahim A, Carran J, Anastassiades T, Jamali F.

J Pharm Pharm Sci. 2006;9(3):359-64.


What is the number of older Canadians needed to screen by measurement of bone density to detect an undiagnosed case of osteoporosis? a population-based study from CaMos.

Sawka AM, Papaioannou A, Josse RG, Murray TM, Ioannidis G, Hanley DA, Prior JC, Thabane L, Papadimitropoulos EA, Gafni A, Pickard L, Anastassiades T, Kirkland S, Adachi JD; CaMos Research Group.

J Clin Densitom. 2006 Oct-Dec;9(4):413-8. Epub 2006 Sep 1.


The action of TNFalpha and TGFbeta include specific alterations of the glycosylation of bovine and human chondrocytes.

Yang X, Yip J, Anastassiades T, Harrison M, Brockhausen I.

Biochim Biophys Acta. 2007 Feb;1773(2):264-72. Epub 2006 Sep 20.


Prevalence of and factors associated with glucosamine use in Canada.

Hopman WM, Towheed TE, Gao Y, Berger C, Joseph L, Vik SA, Hanley DA, Carran J, Anastassiades T.

Osteoarthritis Cartilage. 2006 Dec;14(12):1288-93. Epub 2006 Jul 10.


The natural progression of health-related quality of life: results of a five-year prospective study of SF-36 scores in a normative population.

Hopman WM, Berger C, Joseph L, Towheed T, VandenKerkhof E, Anastassiades T, Adachi JD, Ioannidis G, Brown JP, Hanley DA, Papadimitropoulos EA; CaMos Research Group.

Qual Life Res. 2006 Apr;15(3):527-36.


Driving problems in patients with rheumatoid arthritis.

Cranney AB, Harrison A, Ruhland L, Vaidyanath C, Graham I, Man-Son-Hing M, Jaffey J, Towheed TE, Anastassiades TP, Dwosh II.

J Rheumatol. 2005 Dec;32(12):2337-42.


N-acylation of glucosamine modulates chondrocyte growth, proteoglycan synthesis, and gene expression.

Terry DE, Rees-Milton K, Smith P, Carran J, Pezeshki P, Woods C, Greer P, Anastassiades TP.

J Rheumatol. 2005 Sep;32(9):1775-86.


N-Acyl derivatives of glucosamine as acceptor substrates for galactosyltransferase from bone and cartilage cells.

Brockhausen I, Carran J, McEleney K, Lehotay M, Yang X, Yin L, Anastassiades T.

Carbohydr Res. 2005 Sep 5;340(12):1997-2003.


Glucosamine therapy for treating osteoarthritis.

Towheed TE, Maxwell L, Anastassiades TP, Shea B, Houpt J, Robinson V, Hochberg MC, Wells G.

Cochrane Database Syst Rev. 2005 Apr 18;(2):CD002946. Review.


Biochemical markers for osteoarthritis: from the present to the future and back to the past.

Anastassiades T, Rees-Milton K.

J Rheumatol. 2005 Apr;32(4):578-9. No abstract available.


High performance liquid chromatographic determination of N-butyryl glucosamine in rat plasma.

Aghazadeh-Habashi A, Carran J, Anastassiades T, Jamali F.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 May 5;819(1):91-6.


Artefacts in the mechanical characterization of porcine articular cartilage due to freezing.

Willett TL, Whiteside R, Wild PM, Wyss UP, Anastassiades T.

Proc Inst Mech Eng H. 2005;219(1):23-9.


Risk factors associated with incident clinical vertebral and nonvertebral fractures in postmenopausal women: the Canadian Multicentre Osteoporosis Study (CaMos).

Papaioannou A, Joseph L, Ioannidis G, Berger C, Anastassiades T, Brown JP, Hanley DA, Hopman W, Josse RG, Kirkland S, Murray TM, Olszynski WP, Pickard L, Prior JC, Siminoski K, Adachi JD.

Osteoporos Int. 2005 May;16(5):568-78. Epub 2004 Oct 27.


The effect of TNF-alpha on glycosylation pathways in bovine synoviocytes.

Yang X, Lehotay M, Anastassiades T, Harrison M, Brockhausen I.

Biochem Cell Biol. 2004 Oct;82(5):559-68.


Stability of normative data for the SF-36: results of a three-year prospective study in middle-aged Canadians.

Hopman WM, Berger C, Joseph L, Towheed T, vandenKerkhof E, Anastassiades T, Cranney A, Adachi JD, Loannidis G, Poliquin S, Brown JP, Murray TM, Hanley DA, Papadimitropoulos EA, Tenenhouse A; CaMos Research Group.

Can J Public Health. 2004 Sep-Oct;95(5):387-91.


N-butyryl glucosamine increases matrix gene expression by chondrocytes.

Poustie MW, Carran J, McEleney K, Dixon SJ, Anastassiades TP, Bernier SM.

J Pharmacol Exp Ther. 2004 Nov;311(2):610-6. Epub 2004 Jul 7.


Hyperglycosylation of fibronectin by TGF-beta1-stimulated chondrocytes.

Rees-Milton KJ, Terry D, Anastassiades TP.

Biochem Biophys Res Commun. 2004 May 7;317(3):844-50.


The impact of sampling and measurement on the prevalence of self-reported pain in Canada.

Van Den Kerkhof EG, Hopman WM, Towheed TE, Anastassiades TP, Goldstein DH; Canadian Multicentre Osteoporosis Study Research Group.

Pain Res Manag. 2003 Fall;8(3):157-63.


The association between osteoporotic fractures and health-related quality of life as measured by the Health Utilities Index in the Canadian Multicentre Osteoporosis Study (CaMos).

Adachi JD, Ioannidis G, Pickard L, Berger C, Prior JC, Joseph L, Hanley DA, Olszynski WP, Murray TM, Anastassiades T, Hopman W, Brown JP, Kirkland S, Joyce C, Papaioannou A, Poliquin S, Tenenhouse A, Papadimitropoulos EA.

Osteoporos Int. 2003 Nov;14(11):895-904. Epub 2003 Aug 12.


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