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Items: 37

1.

Author Correction: MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG.

Fets L, Driscoll PC, Grimm F, Jain A, Nunes PM, Gounis M, Doglioni G, Papageorgiou G, Ragan TJ, Campos S, Dos Santos MS, MacRae JI, O'Reilly N, Wright AJ, Benes CH, Courtney KD, House D, Anastasiou D.

Nat Chem Biol. 2019 Dec;15(12):1249. doi: 10.1038/s41589-019-0409-0.

PMID:
31645751
2.

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma.

Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sugiura Y, Sampetrean O, Ikeda Y, Warren M, Sakamoto N, Kitahara S, Yoshino H, Yamashita D, Sumita K, Wolfe K, Lange L, Ikeda S, Shimada H, Minami N, Malhotra A, Morioka S, Ban Y, Asano M, Flanary VL, Ramkissoon A, Chow LML, Kiyokawa J, Mashimo T, Lucey G, Mareninov S, Ozawa T, Onishi N, Okumura K, Terakawa J, Daikoku T, Wise-Draper T, Majd N, Kofuji K, Sasaki M, Mori M, Kanemura Y, Smith EP, Anastasiou D, Wakimoto H, Holland EC, Yong WH, Horbinski C, Nakano I, DeBerardinis RJ, Bachoo RM, Mischel PS, Yasui W, Suematsu M, Saya H, Soga T, Grummt I, Bierhoff H, Sasaki AT.

Nat Cell Biol. 2019 Aug;21(8):1003-1014. doi: 10.1038/s41556-019-0363-9. Epub 2019 Aug 1.

PMID:
31371825
3.

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation.

Macpherson JA, Theisen A, Masino L, Fets L, Driscoll PC, Encheva V, Snijders AP, Martin SR, Kleinjung J, Barran PE, Fraternali F, Anastasiou D.

Elife. 2019 Jul 2;8. pii: e45068. doi: 10.7554/eLife.45068.

4.

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer.

Morotti M, Bridges E, Valli A, Choudhry H, Sheldon H, Wigfield S, Gray N, Zois CE, Grimm F, Jones D, Teoh EJ, Cheng WC, Lord S, Anastasiou D, Haider S, McIntyre A, Goberdhan DCI, Buffa F, Harris AL.

Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12452-12461. doi: 10.1073/pnas.1818521116. Epub 2019 May 31.

5.

mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1-induced collagen biosynthesis.

Selvarajah B, Azuelos I, Platé M, Guillotin D, Forty EJ, Contento G, Woodcock HV, Redding M, Taylor A, Brunori G, Durrenberger PF, Ronzoni R, Blanchard AD, Mercer PF, Anastasiou D, Chambers RC.

Sci Signal. 2019 May 21;12(582). pii: eaav3048. doi: 10.1126/scisignal.aav3048.

6.

PI3K/AKT pathway genetic alterations and dysregulation of expression in bladder cancer.

Kachrilas S, Dellis A, Papatsoris A, Avgeris S, Anastasiou D, Gavriil A, Horti M, Tseleni Balafouta S, Livadas K, Stravopodis DJ, Alivizatos G, Voutsinas GE, Deliveliotis C.

J BUON. 2019 Jan-Feb;24(1):329-337.

7.

Endrew and FAPE: Concepts and Implications for All Students With Disabilities.

Kauffman JM, Wiley AL, Travers JC, Badar J, Anastasiou D.

Behav Modif. 2019 Mar 5:145445519832990. doi: 10.1177/0145445519832990. [Epub ahead of print]

PMID:
30832492
8.

MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG.

Fets L, Driscoll PC, Grimm F, Jain A, Nunes PM, Gounis M, Doglioni G, Papageorgiou G, Ragan TJ, Campos S, Silva Dos Santos M, MacRae JI, O'Reilly N, Wright AJ, Benes CH, Courtney KD, House D, Anastasiou D.

Nat Chem Biol. 2018 Nov;14(11):1032-1042. doi: 10.1038/s41589-018-0136-y. Epub 2018 Oct 8. Erratum in: Nat Chem Biol. 2019 Dec;15(12):1249.

9.

An engineered photoswitchable mammalian pyruvate kinase.

Gehrig S, Macpherson JA, Driscoll PC, Symon A, Martin SR, MacRae JI, Kleinjung J, Fraternali F, Anastasiou D.

FEBS J. 2017 Sep;284(18):2955-2980. doi: 10.1111/febs.14175. Epub 2017 Aug 16.

10.

Allosteric regulation of metabolism in cancer: endogenous mechanisms and considerations for drug design.

Macpherson JA, Anastasiou D.

Curr Opin Biotechnol. 2017 Dec;48:102-110. doi: 10.1016/j.copbio.2017.03.022. Epub 2017 Apr 18. Review.

PMID:
28431259
11.

PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation.

Gupta A, Anjomani-Virmouni S, Koundouros N, Dimitriadi M, Choo-Wing R, Valle A, Zheng Y, Chiu YH, Agnihotri S, Zadeh G, Asara JM, Anastasiou D, Arends MJ, Cantley LC, Poulogiannis G.

Mol Cell. 2017 Mar 16;65(6):999-1013.e7. doi: 10.1016/j.molcel.2017.02.019.

12.

Daptomycin for Complicated Skin Infections: A Randomized Trial.

Bradley J, Glasser C, Patino H, Arnold SR, Arrieta A, Congeni B, Daum RS, Kojaoghlanian T, Yoon M, Anastasiou D, Wolf DJ, Bokesch P.

Pediatrics. 2017 Mar;139(3). pii: e20162477. doi: 10.1542/peds.2016-2477. Epub 2017 Feb 15.

13.

Tumour microenvironment factors shaping the cancer metabolism landscape.

Anastasiou D.

Br J Cancer. 2017 Jan;116(3):277-286. doi: 10.1038/bjc.2016.412. Epub 2016 Dec 22. Review.

14.

Hippo's Q for a big liver.

Anastasiou D.

Nat Cell Biol. 2016 Jul 27;18(8):835-7. doi: 10.1038/ncb3391.

PMID:
27463251
15.

Gas Chromatography Coupled to Mass Spectrometry (GC-MS) to Study Metabolism in Cultured Cells.

Grimm F, Fets L, Anastasiou D.

Adv Exp Med Biol. 2016;899:59-88. doi: 10.1007/978-3-319-26666-4_5.

PMID:
27325262
16.

The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.

Sumita K, Lo YH, Takeuchi K, Senda M, Kofuji S, Ikeda Y, Terakawa J, Sasaki M, Yoshino H, Majd N, Zheng Y, Kahoud ER, Yokota T, Emerling BM, Asara JM, Ishida T, Locasale JW, Daikoku T, Anastasiou D, Senda T, Sasaki AT.

Mol Cell. 2016 Jan 21;61(2):187-98. doi: 10.1016/j.molcel.2015.12.011. Epub 2016 Jan 7.

17.

Degradation of activated K-Ras orthologue via K-Ras-specific lysine residues is required for cytokinesis.

Sumita K, Yoshino H, Sasaki M, Majd N, Kahoud ER, Takahashi H, Takeuchi K, Kuroda T, Lee S, Charest PG, Takeda K, Asara JM, Firtel RA, Anastasiou D, Sasaki AT.

J Biol Chem. 2014 Feb 14;289(7):3950-9. doi: 10.1074/jbc.M113.531178. Epub 2013 Dec 13.

18.

p73 keeps metabolic control in the family.

Fets L, Anastasiou D.

Nat Cell Biol. 2013 Aug;15(8):891-3. doi: 10.1038/ncb2810.

PMID:
23907193
19.

ML265: A potent PKM2 activator induces tetramerization and reduces tumor formation and size in a mouse xenograft model.

Jiang J, Walsh MJ, Brimacombe KR, Anastasiou D, Yu Y, Israelsen WJ, Hong BS, Tempel W, Dimov S, Veith H, Yang H, Kung C, Yen KE, Dang L, Salituro F, Auld DS, Park HW, Vander Heiden MG, Thomas CJ, Shen M, Boxer MB.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Mar 16 [updated 2013 May 8].

20.

ML285 affects reactive oxygen species’ inhibition of pyruvate kinase M2.

Brimacombe KR, Anastasiou D, Hong BS, Tempel W, Dimov S, Veith H, Auld DS, Vander Heiden MG, Thomas CJ, Park HW, Shen M, Cantley LC, Boxer MB.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Aug 3 [updated 2013 May 8].

21.

The social model of disability: dichotomy between impairment and disability.

Anastasiou D, Kauffman JM.

J Med Philos. 2013 Aug;38(4):441-59. doi: 10.1093/jmp/jht026.

PMID:
23856481
22.

Metformin: a case of divide and conquer.

Anastasiou D.

Breast Cancer Res. 2013 Mar 11;15(2):306. doi: 10.1186/bcr3387.

23.

mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.

Kalaitzidis D, Sykes SM, Wang Z, Punt N, Tang Y, Ragu C, Sinha AU, Lane SW, Souza AL, Clish CB, Anastasiou D, Gilliland DG, Scadden DT, Guertin DA, Armstrong SA.

Cell Stem Cell. 2012 Sep 7;11(3):429-39. doi: 10.1016/j.stem.2012.06.009.

24.

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.

Anastasiou D, Yu Y, Israelsen WJ, Jiang JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, Yang H, Mattaini KR, Metallo CM, Fiske BP, Courtney KD, Malstrom S, Khan TM, Kung C, Skoumbourdis AP, Veith H, Southall N, Walsh MJ, Brimacombe KR, Leister W, Lunt SY, Johnson ZR, Yen KE, Kunii K, Davidson SM, Christofk HR, Austin CP, Inglese J, Harris MH, Asara JM, Stephanopoulos G, Salituro FG, Jin S, Dang L, Auld DS, Park HW, Cantley LC, Thomas CJ, Vander Heiden MG.

Nat Chem Biol. 2012 Oct;8(10):839-47. Erratum in: Nat Chem Biol. 2012 Dec;8(12):1008.

25.

Randomized controlled trial of the safety and efficacy of Daptomycin versus standard-of-care therapy for management of patients with osteomyelitis associated with prosthetic devices undergoing two-stage revision arthroplasty.

Byren I, Rege S, Campanaro E, Yankelev S, Anastasiou D, Kuropatkin G, Evans R.

Antimicrob Agents Chemother. 2012 Nov;56(11):5626-32. doi: 10.1128/AAC.00038-12. Epub 2012 Aug 20.

26.

Systemic elevation of PTEN induces a tumor-suppressive metabolic state.

Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, de Boer VC, Anastasiou D, Ito K, Sasaki AT, Rameh L, Carracedo A, Vander Heiden MG, Cantley LC, Pinton P, Haigis MC, Pandolfi PP.

Cell. 2012 Mar 30;149(1):49-62. doi: 10.1016/j.cell.2012.02.030. Epub 2012 Mar 6.

27.

Breathless cancer cells get fat on glutamine.

Anastasiou D, Cantley LC.

Cell Res. 2012 Mar;22(3):443-6. doi: 10.1038/cr.2012.5. Epub 2012 Jan 3. No abstract available.

28.

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.

Anastasiou D, Poulogiannis G, Asara JM, Boxer MB, Jiang JK, Shen M, Bellinger G, Sasaki AT, Locasale JW, Auld DS, Thomas CJ, Vander Heiden MG, Cantley LC.

Science. 2011 Dec 2;334(6060):1278-83. doi: 10.1126/science.1211485. Epub 2011 Nov 3.

29.

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.

Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG.

Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890.

30.

Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.

Sasaki AT, Carracedo A, Locasale JW, Anastasiou D, Takeuchi K, Kahoud ER, Haviv S, Asara JM, Pandolfi PP, Cantley LC.

Sci Signal. 2011 Mar 8;4(163):ra13. doi: 10.1126/scisignal.2001518.

31.

Evidence for daptomycin Etest lot-related MIC elevations for Staphylococcus aureus.

Friedrich L, Thorne G, Steenbergen JN, Anastasiou D, Koeth L.

Diagn Microbiol Infect Dis. 2009 Nov;65(3):306-11. doi: 10.1016/j.diagmicrobio.2009.07.012. Epub 2009 Sep 16.

PMID:
19762196
32.

Grade-dependent effects on cell cycle progression and apoptosis in response to doxorubicin in human bladder cancer cell lines.

Stravopodis DJ, Karkoulis PK, Konstantakou EG, Melachroinou S, Lampidonis AD, Anastasiou D, Kachrilas S, Messini-Nikolaki N, Papassideri IS, Aravantinos G, Margaritis LH, Voutsinas GE.

Int J Oncol. 2009 Jan;34(1):137-60.

PMID:
19082486
33.

In vitro activity of daptomycin against multidrug-resistant Staphylococcus aureus and S. aureus with known virulence factors, including community-acquired methicillin-resistant isolates.

Anastasiou DM, Morgan M, Ruane PJ, Steenbergen JN, Katz BD, Alder JD, Thorne GM.

Diagn Microbiol Infect Dis. 2008 Jul;61(3):339-42. doi: 10.1016/j.diagmicrobio.2008.01.012. Epub 2008 Mar 4.

PMID:
18304772
34.

SIRT1: linking adaptive cellular responses to aging-associated changes in organismal physiology.

Anastasiou D, Krek W.

Physiology (Bethesda). 2006 Dec;21:404-10. Review.

35.

In vitro activity of daptomycin against clinical isolates with reduced susceptibilities to linezolid and quinupristin/dalfopristin.

Anastasiou DM, Thorne GM, Luperchio SA, Alder JD.

Int J Antimicrob Agents. 2006 Nov;28(5):385-8. Review.

PMID:
17046205
36.

The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II.

Yart A, Gstaiger M, Wirbelauer C, Pecnik M, Anastasiou D, Hess D, Krek W.

Mol Cell Biol. 2005 Jun;25(12):5052-60.

37.

Antiviral activity of influenza virus M1 zinc finger peptides.

Nasser EH, Judd AK, Sanchez A, Anastasiou D, Bucher DJ.

J Virol. 1996 Dec;70(12):8639-44.

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