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Items: 28


TLR3 absence confers increased survival with improved macrophage activity against pneumonia.

Suresh MV, Dolgachev VA, Zhang B, Balijepalli S, Swamy S, Mooliyil J, Kralovich G, Thomas B, Machado-Aranda D, Karmakar M, Lalwani S, Subramanian A, Anantharam A, Moore BB, Raghavendran K.

JCI Insight. 2019 Dec 5;4(23). pii: 131195. doi: 10.1172/jci.insight.131195.


Unraveling the mechanisms of calcium-dependent secretion.

Anantharam A, Kreutzberger AJB.

J Gen Physiol. 2019 Apr 1;151(4):417-434. doi: 10.1085/jgp.201812298. Epub 2019 Feb 19. Review.


Perivascular Adipocytes Store Norepinephrine by Vesicular Transport.

Ahmad MF, Ferland D, Ayala-Lopez N, Contreras GA, Darios E, Thompson J, Ismail A, Thelen K, Moeser AJ, Burnett R, Anantharam A, Watts SW.

Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):188-199. doi: 10.1161/ATVBAHA.118.311720.


Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production.

de Rubio RG, Ransom RF, Malik S, Yule DI, Anantharam A, Smrcka AV.

Sci Signal. 2018 Sep 11;11(547). pii: eaan1210. doi: 10.1126/scisignal.aan1210.


A simple supported tubulated bilayer system for evaluating protein-mediated membrane remodeling.

Schenk NA, Dahl PJ, Hanna MG 4th, Audhya A, Tall GG, Knight JD, Anantharam A.

Chem Phys Lipids. 2018 Sep;215:18-28. doi: 10.1016/j.chemphyslip.2018.06.002. Epub 2018 Jul 22.


The high-affinity calcium sensor synaptotagmin-7 serves multiple roles in regulated exocytosis.

MacDougall DD, Lin Z, Chon NL, Jackman SL, Lin H, Knight JD, Anantharam A.

J Gen Physiol. 2018 Jun 4;150(6):783-807. doi: 10.1085/jgp.201711944. Epub 2018 May 24. Review.


The synaptotagmin C2B domain calcium-binding loops modulate the rate of fusion pore expansion.

Bendahmane M, Bohannon KP, Bradberry MM, Rao TC, Schmidtke MW, Abbineni PS, Chon NL, Tran S, Lin H, Chapman ER, Knight JD, Anantharam A.

Mol Biol Cell. 2018 Feb 14;29(7):773-880. doi: 10.1091/mbc.E17-11-0623. [Epub ahead of print]


Synaptotagmin isoforms confer distinct activation kinetics and dynamics to chromaffin cell granules.

Rao TC, Santana Rodriguez Z, Bradberry MM, Ranski AH, Dahl PJ, Schmidtke MW, Jenkins PM, Axelrod D, Chapman ER, Giovannucci DR, Anantharam A.

J Gen Physiol. 2017 Aug 7;149(8):763-780. doi: 10.1085/jgp.201711757. Epub 2017 Jul 7.


Food deprivation induces presynaptic plasticity in the autonomic nervous system.

Holz RW, Anantharam A.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):5766-7. doi: 10.1073/pnas.1605618113. Epub 2016 May 13. No abstract available.


Lumenal protein within secretory granules affects fusion pore expansion.

Weiss AN, Anantharam A, Bittner MA, Axelrod D, Holz RW.

Biophys J. 2014 Jul 1;107(1):26-33. doi: 10.1016/j.bpj.2014.04.064.


Real-time investigation of plasma membrane deformation and fusion pore expansion using polarized Total Internal Reflection Fluorescence Microscopy.

Passmore DR, Rao T, Anantharam A.

Methods Mol Biol. 2014;1174:263-73. doi: 10.1007/978-1-4939-0944-5_18.


Distinct fusion properties of synaptotagmin-1 and synaptotagmin-7 bearing dense core granules.

Rao TC, Passmore DR, Peleman AR, Das M, Chapman ER, Anantharam A.

Mol Biol Cell. 2014 Aug 15;25(16):2416-27. doi: 10.1091/mbc.E14-02-0702. Epub 2014 Jun 18.


Imaging plasma membrane deformations with pTIRFM.

Passmore DR, Rao TC, Peleman AR, Anantharam A.

J Vis Exp. 2014 Apr 2;(86). doi: 10.3791/51334.


Ultrafast detection and quantification of brain signaling molecules with carbon fiber microelectrodes.

Lama RD, Charlson K, Anantharam A, Hashemi P.

Anal Chem. 2012 Oct 2;84(19):8096-101. doi: 10.1021/ac301670h. Epub 2012 Aug 23.


Real-time imaging of plasma membrane deformations reveals pre-fusion membrane curvature changes and a role for dynamin in the regulation of fusion pore expansion.

Anantharam A, Axelrod D, Holz RW.

J Neurochem. 2012 Aug;122(4):661-71. doi: 10.1111/j.1471-4159.2012.07816.x. Epub 2012 Jun 27. Review.


Subunit-dependent axonal trafficking of distinct alpha heteromeric potassium channel complexes.

Jenkins PM, McIntyre JC, Zhang L, Anantharam A, Vesely ED, Arendt KL, Carruthers CJ, Kerppola TK, Iñiguez-Lluhí JA, Holz RW, Sutton MA, Martens JR.

J Neurosci. 2011 Sep 14;31(37):13224-35. doi: 10.1523/JNEUROSCI.0976-11.2011.


A new role for the dynamin GTPase in the regulation of fusion pore expansion.

Anantharam A, Bittner MA, Aikman RL, Stuenkel EL, Schmid SL, Axelrod D, Holz RW.

Mol Biol Cell. 2011 Jun 1;22(11):1907-18. doi: 10.1091/mbc.E11-02-0101. Epub 2011 Apr 1.


Polarized TIRFM reveals changes in plasma membrane topology before and during granule fusion.

Anantharam A, Axelrod D, Holz RW.

Cell Mol Neurobiol. 2010 Nov;30(8):1343-9. doi: 10.1007/s10571-010-9590-0.


Localized topological changes of the plasma membrane upon exocytosis visualized by polarized TIRFM.

Anantharam A, Onoa B, Edwards RH, Holz RW, Axelrod D.

J Cell Biol. 2010 Feb 8;188(3):415-28. doi: 10.1083/jcb.200908010.


Determination of epithelial Na+ channel subunit stoichiometry from single-channel conductances.

Anantharam A, Palmer LG.

J Gen Physiol. 2007 Jul;130(1):55-70. Epub 2007 Jun 11.


The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion.

Roepke TK, Anantharam A, Kirchhoff P, Busque SM, Young JB, Geibel JP, Lerner DJ, Abbott GW.

J Biol Chem. 2006 Aug 18;281(33):23740-7. Epub 2006 Jun 5.


Open probability of the epithelial sodium channel is regulated by intracellular sodium.

Anantharam A, Tian Y, Palmer LG.

J Physiol. 2006 Jul 15;574(Pt 2):333-47. Epub 2006 May 11.


Does hERG coassemble with a beta subunit? Evidence for roles of MinK and MiRP1.

Anantharam A, Abbott GW.

Novartis Found Symp. 2005;266:100-12; discussion 112-7, 155-8. Review.


N-type Ca2+ channels as scaffold proteins in the assembly of signaling molecules for GABAB receptor effects.

Richman RW, Tombler E, Lau KK, Anantharam A, Rodriguez J, O'Bryan JP, Diversé-Pierluissi MA.

J Biol Chem. 2004 Jun 4;279(23):24649-58. Epub 2004 Mar 26. Retraction in: J Biol Chem. 2011 Jun 17;286(24):21952.


Pharmacogenetic considerations in diseases of cardiac ion channels.

Anantharam A, Markowitz SM, Abbott GW.

J Pharmacol Exp Ther. 2003 Dec;307(3):831-8. Epub 2003 Oct 15. Review.


RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies.

Anantharam A, Lewis A, Panaghie G, Gordon E, McCrossan ZA, Lerner DJ, Abbott GW.

J Biol Chem. 2003 Apr 4;278(14):11739-45. Epub 2003 Jan 15.


Biochemical approaches to study interaction of calcium channels with RGS12 in primary neuronal cultures.

Anantharam A, Diversé-Pierluissi MA.

Methods Enzymol. 2002;345:60-70. No abstract available.


Studies of endogenous G-protein-mediated pathways in neurons by whole-cell electrophysiology.

Anantharam A, Diversé-Pierluissi MA.

Methods Enzymol. 2002;345:51-9. No abstract available.


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