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Items: 23

1.

Constitutive Androstane Receptor Differentially Regulates Bile Acid Homeostasis in Mouse Models of Intrahepatic Cholestasis.

Kim KH, Choi JM, Li F, Dong B, Wooton-Kee CR, Arizpe A, Anakk S, Jung SY, Hartig SM, Moore DD.

Hepatol Commun. 2018 Dec 4;3(1):147-159. doi: 10.1002/hep4.1274. eCollection 2019 Jan.

2.

Identification of IQ motif-containing GTPase-activating protein 1 as a regulator of long-term ketosis.

Erickson HL, Anakk S.

JCI Insight. 2018 Nov 2;3(21). pii: 99866. doi: 10.1172/jci.insight.99866.

3.

Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration.

Bangru S, Arif W, Seimetz J, Bhate A, Chen J, Rashan EH, Carstens RP, Anakk S, Kalsotra A.

Nat Struct Mol Biol. 2018 Oct;25(10):928-939. doi: 10.1038/s41594-018-0129-2. Epub 2018 Sep 24.

PMID:
30250226
4.

Xenobiotic Nuclear Receptor Signaling Determines Molecular Pathogenesis of Progressive Familial Intrahepatic Cholestasis.

Kim KH, Choi JM, Li F, Arizpe A, Wooton-Kee CR, Anakk S, Jung SY, Finegold MJ, Moore DD.

Endocrinology. 2018 Jun 1;159(6):2435-2446. doi: 10.1210/en.2018-00110.

PMID:
29718219
5.

Small heterodimer partner deletion prevents hepatic steatosis and when combined with farnesoid X receptor loss protects against type 2 diabetes in mice.

Akinrotimi O, Riessen R, VanDuyne P, Park JE, Lee YK, Wong LJ, Zavacki AM, Schoonjans K, Anakk S.

Hepatology. 2017 Dec;66(6):1854-1865. doi: 10.1002/hep.29305. Epub 2017 Oct 30.

6.

Hepatic FXR/SHP axis modulates systemic glucose and fatty acid homeostasis in aged mice.

Kim KH, Choi S, Zhou Y, Kim EY, Lee JM, Saha PK, Anakk S, Moore DD.

Hepatology. 2017 Aug;66(2):498-509. doi: 10.1002/hep.29199. Epub 2017 Jun 26.

PMID:
28378930
7.

Bile acid excess induces cardiomyopathy and metabolic dysfunctions in the heart.

Desai MS, Mathur B, Eblimit Z, Vasquez H, Taegtmeyer H, Karpen SJ, Penny DJ, Moore DD, Anakk S.

Hepatology. 2017 Jan;65(1):189-201. doi: 10.1002/hep.28890. Epub 2016 Nov 29.

8.

ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation.

Bhate A, Parker DJ, Bebee TW, Ahn J, Arif W, Rashan EH, Chorghade S, Chau A, Lee JH, Anakk S, Carstens RP, Xiao X, Kalsotra A.

Nat Commun. 2015 Nov 4;6:8768. doi: 10.1038/ncomms9768.

9.

Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.

Chow EC, Magomedova L, Quach HP, Patel R, Durk MR, Fan J, Maeng HJ, Irondi K, Anakk S, Moore DD, Cummins CL, Pang KS.

Gastroenterology. 2014 Apr;146(4):1048-59. doi: 10.1053/j.gastro.2013.12.027. Epub 2013 Dec 21.

PMID:
24365583
10.

Bile acids activate YAP to promote liver carcinogenesis.

Anakk S, Bhosale M, Schmidt VA, Johnson RL, Finegold MJ, Moore DD.

Cell Rep. 2013 Nov 27;5(4):1060-9. doi: 10.1016/j.celrep.2013.10.030. Epub 2013 Nov 21.

11.

Cysteine sulfinic acid decarboxylase regulation: A role for farnesoid X receptor and small heterodimer partner in murine hepatic taurine metabolism.

Kerr TA, Matsumoto Y, Matsumoto H, Xie Y, Hirschberger LL, Stipanuk MH, Anakk S, Moore DD, Watanabe M, Kennedy S, Davidson NO.

Hepatol Res. 2014 Oct;44(10):E218-28. doi: 10.1111/hepr.12230. Epub 2013 Oct 18.

12.

Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer.

Jiang Y, Iakova P, Jin J, Sullivan E, Sharin V, Hong IH, Anakk S, Mayor A, Darlington G, Finegold M, Moore D, Timchenko NA.

Hepatology. 2013 Mar;57(3):1098-106. doi: 10.1002/hep.26146. Epub 2013 Feb 15.

13.

Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner.

Park YJ, Kim SC, Kim J, Anakk S, Lee JM, Tseng HT, Yechoor V, Park J, Choi JS, Jang HC, Lee KU, Novak CM, Moore DD, Lee YK.

J Lipid Res. 2011 Dec;52(12):2234-44. doi: 10.1194/jlr.M016048. Epub 2011 Sep 23.

14.

Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor α.

Dwivedi SK, Singh N, Kumari R, Mishra JS, Tripathi S, Banerjee P, Shah P, Kukshal V, Tyagi AM, Gaikwad AN, Chaturvedi RK, Mishra DP, Trivedi AK, Sanyal S, Chattopadhyay N, Ramachandran R, Siddiqi MI, Bandyopadhyay A, Arora A, Lundåsen T, Anakk SP, Moore DD, Sanyal S.

Mol Endocrinol. 2011 Jun;25(6):922-32. doi: 10.1210/me.2010-0512. Epub 2011 Apr 14.

15.

Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis.

Anakk S, Watanabe M, Ochsner SA, McKenna NJ, Finegold MJ, Moore DD.

J Clin Invest. 2011 Jan;121(1):86-95. doi: 10.1172/JCI42846. Epub 2010 Dec 1.

16.

Catalytic characterization and cytokine mediated regulation of cytochrome P450 4Fs in rat hepatocytes.

Kalsotra A, Anakk S, Brommer CL, Kikuta Y, Morgan ET, Strobel HW.

Arch Biochem Biophys. 2007 May 1;461(1):104-12. Epub 2007 Mar 15.

17.

Gender dictates the nuclear receptor-mediated regulation of CYP3A44.

Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW.

Drug Metab Dispos. 2007 Jan;35(1):36-42. Epub 2006 Oct 4.

PMID:
17020958
18.

Brain trauma leads to enhanced lung inflammation and injury: evidence for role of P4504Fs in resolution.

Kalsotra A, Zhao J, Anakk S, Dash PK, Strobel HW.

J Cereb Blood Flow Metab. 2007 May;27(5):963-74. Epub 2006 Sep 20.

PMID:
16985506
19.

Renal localization, expression, and developmental regulation of P450 4F cytochromes in three substrains of spontaneously hypertensive rats.

Kalsotra A, Cui X, Anakk S, Hinojos CA, Doris PA, Strobel HW.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):423-31. Epub 2005 Aug 25.

PMID:
16182239
20.

CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.

Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW.

Pharmacogenomics J. 2004;4(2):91-101.

PMID:
14770174
21.

Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors.

Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJ, Strobel HW.

FASEB J. 2003 Sep;17(12):1736-8. Epub 2003 Jul 3.

PMID:
12958193
22.

Insights into gender bias: rat cytochrome P450 3A9.

Anakk S, Ku CY, Vore M, Strobel HW.

J Pharmacol Exp Ther. 2003 May;305(2):703-9. Epub 2003 Feb 11.

PMID:
12606633
23.

Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats.

Kalsotra A, Anakk S, Boehme CL, Strobel HW.

Drug Metab Dispos. 2002 Sep;30(9):1022-8.

PMID:
12167568

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