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Items: 1 to 50 of 128

1.

High resolution analysis of the intracellular proteome of cervical cancer cell lines unveils novel regulators of cervical carcinogenesis.

Pappa KI, Lygirou V, Kontostathi G, Makridakis M, Vougas K, Sfakianakis A, Daskalakis G, Zoidakis J, Anagnou NP.

Oncol Rep. 2019 Aug 8. doi: 10.3892/or.2019.7269. [Epub ahead of print]

PMID:
31524267
2.

Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China.

Büning H, Griesenbach U, Fehse B, Ylä-Herttuala S, Anagnou NP, van Beusechem V, Raya A, Verhoeyen E.

Hum Gene Ther. 2018 Dec;29(12):1337-1338. doi: 10.1089/hum.2018.29081.con. Epub 2018 Dec 4. No abstract available.

PMID:
30511888
3.

A Novel BaEVRless-Pseudotyped γ-Globin Lentiviral Vector Drives High and Stable Fetal Hemoglobin Expression and Improves Thalassemic Erythropoiesis In Vitro.

Drakopoulou E, Georgomanoli M, Lederer CW, Kleanthous M, Costa C, Bernadin O, Cosset FL, Voskaridou E, Verhoeyen E, Papanikolaou E, Anagnou NP.

Hum Gene Ther. 2019 May;30(5):601-617. doi: 10.1089/hum.2018.022. Epub 2019 Mar 15.

PMID:
30324804
4.

Membrane proteomics of cervical cancer cell lines reveal insights on the process of cervical carcinogenesis.

Pappa KI, Christou P, Xholi A, Mermelekas G, Kontostathi G, Lygirou V, Makridakis M, Zoidakis J, Anagnou NP.

Int J Oncol. 2018 Nov;53(5):2111-2122. doi: 10.3892/ijo.2018.4518. Epub 2018 Aug 7.

PMID:
30106135
5.

Novel structural approaches concerning HPV proteins: Insight into targeted therapies for cervical cancer (Review).

Pappa KI, Kontostathi G, Lygirou V, Zoidakis J, Anagnou NP.

Oncol Rep. 2018 Apr;39(4):1547-1554. doi: 10.3892/or.2018.6257. Epub 2018 Feb 9. Review.

PMID:
29436691
6.

High Resolution Proteomic Analysis of the Cervical Cancer Cell Lines Secretome Documents Deregulation of Multiple Proteases.

Pappa KI, Kontostathi G, Makridakis M, Lygirou V, Zoidakis J, Daskalakis G, Anagnou NP.

Cancer Genomics Proteomics. 2017 Nov-Dec;14(6):507-521. Review.

7.

Proteomic Analysis of Normal and Cancer Cervical Cell Lines Reveals Deregulation of Cytoskeleton-associated Proteins.

Pappa KI, Lygirou V, Kontostathi G, Zoidakis J, Makridakis M, Vougas K, Daskalakis G, Polyzos A, Anagnou NP.

Cancer Genomics Proteomics. 2017 Jul-Aug;14(4):253-266.

8.

Origin and spread of human mitochondrial DNA haplogroup U7.

Sahakyan H, Hooshiar Kashani B, Tamang R, Kushniarevich A, Francis A, Costa MD, Pathak AK, Khachatryan Z, Sharma I, van Oven M, Parik J, Hovhannisyan H, Metspalu E, Pennarun E, Karmin M, Tamm E, Tambets K, Bahmanimehr A, Reisberg T, Reidla M, Achilli A, Olivieri A, Gandini F, Perego UA, Al-Zahery N, Houshmand M, Sanati MH, Soares P, Rai E, Šarac J, Šarić T, Sharma V, Pereira L, Fernandes V, Černý V, Farjadian S, Singh DP, Azakli H, Üstek D, Ekomasova Trofimova N, Kutuev I, Litvinov S, Bermisheva M, Khusnutdinova EK, Rai N, Singh M, Singh VK, Reddy AG, Tolk HV, Cvjetan S, Lauc LB, Rudan P, Michalodimitrakis EN, Anagnou NP, Pappa KI, Golubenko MV, Orekhov V, Borinskaya SA, Kaldma K, Schauer MA, Simionescu M, Gusar V, Grechanina E, Govindaraj P, Voevoda M, Damba L, Sharma S, Singh L, Semino O, Behar DM, Yepiskoposyan L, Richards MB, Metspalu M, Kivisild T, Thangaraj K, Endicott P, Chaubey G, Torroni A, Villems R.

Sci Rep. 2017 Apr 7;7:46044. doi: 10.1038/srep46044.

9.

The Q192R polymorphism of the paraoxonase-1 (PON1) gene is associated with susceptibility to gestational diabetes mellitus in the Greek population.

Pappa KI, Gazouli M, Anastasiou E, Loutradis D, Anagnou NP.

Gynecol Endocrinol. 2017 Aug;33(8):617-620. doi: 10.1080/09513590.2017.1302419. Epub 2017 Mar 28.

PMID:
28347194
10.

Cervical Cancer Cell Line Secretome Highlights the Roles of Transforming Growth Factor-Beta-Induced Protein ig-h3, Peroxiredoxin-2, and NRF2 on Cervical Carcinogenesis.

Kontostathi G, Zoidakis J, Makridakis M, Lygirou V, Mermelekas G, Papadopoulos T, Vougas K, Vlamis-Gardikas A, Drakakis P, Loutradis D, Vlahou A, Anagnou NP, Pappa KI.

Biomed Res Int. 2017;2017:4180703. doi: 10.1155/2017/4180703. Epub 2017 Feb 2.

11.

miR-26a Mediates Adipogenesis of Amniotic Fluid Mesenchymal Stem/Stromal Cells via PTEN, Cyclin E1, and CDK6.

Trohatou O, Zagoura D, Orfanos NK, Pappa KI, Marinos E, Anagnou NP, Roubelakis MG.

Stem Cells Dev. 2017 Apr 1;26(7):482-494. doi: 10.1089/scd.2016.0203. Epub 2017 Feb 13.

PMID:
28068868
12.

Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24M-based bladder cancer models.

Frantzi M, Klimou Z, Makridakis M, Zoidakis J, Latosinska A, Borràs DM, Janssen B, Giannopoulou I, Lygirou V, Lazaris AC, Anagnou NP, Mischak H, Roubelakis MG, Vlahou A.

Oncotarget. 2016 Oct 25;7(43):70750-70768. doi: 10.18632/oncotarget.12218.

13.

Proteomics approaches in cervical cancer: focus on the discovery of biomarkers for diagnosis and drug treatment monitoring.

Kontostathi G, Zoidakis J, Anagnou NP, Pappa KI, Vlahou A, Makridakis M.

Expert Rev Proteomics. 2016 Aug;13(8):731-45. doi: 10.1080/14789450.2016.1210514. Review.

PMID:
27398979
14.

Development and Validation of Urine-based Peptide Biomarker Panels for Detecting Bladder Cancer in a Multi-center Study.

Frantzi M, van Kessel KE, Zwarthoff EC, Marquez M, Rava M, Malats N, Merseburger AS, Katafigiotis I, Stravodimos K, Mullen W, Zoidakis J, Makridakis M, Pejchinovski M, Critselis E, Lichtinghagen R, Brand K, Dakna M, Roubelakis MG, Theodorescu D, Vlahou A, Mischak H, Anagnou NP.

Clin Cancer Res. 2016 Aug 15;22(16):4077-86. doi: 10.1158/1078-0432.CCR-15-2715. Epub 2016 Mar 29.

15.

Profiling of Discrete Gynecological Cancers Reveals Novel Transcriptional Modules and Common Features Shared by Other Cancer Types and Embryonic Stem Cells.

Pappa KI, Polyzos A, Jacob-Hirsch J, Amariglio N, Vlachos GD, Loutradis D, Anagnou NP.

PLoS One. 2015 Nov 11;10(11):e0142229. doi: 10.1371/journal.pone.0142229. eCollection 2015.

16.

Low mutational burden of eight genes involved in the MAPK/ERK, PI3K/AKT, and GNAQ/11 pathways in female genital tract primary melanomas.

Pappa KI, Vlachos GD, Roubelakis M, Vlachos DE, Kalafati TG, Loutradis D, Anagnou NP.

Biomed Res Int. 2015;2015:303791. doi: 10.1155/2015/303791. Epub 2015 Jan 28.

17.

Cell cycle status of CD34(+) hemopoietic stem cells determines lentiviral integration in actively transcribed and development-related genes.

Papanikolaou E, Paruzynski A, Kasampalidis I, Deichmann A, Stamateris E, Schmidt M, von Kalle C, Anagnou NP.

Mol Ther. 2015 Apr;23(4):683-96. doi: 10.1038/mt.2014.246. Epub 2014 Dec 19.

18.

Quantum dots-bevacizumab complexes for in vivo imaging of tumors.

Gazouli M, Bouziotis P, Lyberopoulou A, Ikonomopoulos J, Papalois A, Anagnou NP, Efstathopoulos EP.

In Vivo. 2014 Nov-Dec;28(6):1091-5.

PMID:
25398804
19.

Comparative assessment of lymph node micrometastasis in cervical, endometrial and vulvar cancer: insights on the real time qRT-PCR approach versus immunohistochemistry, employing dual molecular markers.

Pappa KI, Rodolakis A, Christodoulou I, Gazouli M, Markaki S, Antsaklis A, Anagnou NP.

Biomed Res Int. 2014;2014:187684. doi: 10.1155/2014/187684. Epub 2014 Jan 2.

20.

Platelet-rich plasma (PRP) promotes fetal mesenchymal stem/stromal cell migration and wound healing process.

Roubelakis MG, Trohatou O, Roubelakis A, Mili E, Kalaitzopoulos I, Papazoglou G, Pappa KI, Anagnou NP.

Stem Cell Rev Rep. 2014 Jun;10(3):417-28. doi: 10.1007/s12015-013-9494-8.

PMID:
24500853
21.

3D molecular modeling and evolutionary study of the Trypanosoma brucei DNA Topoisomerase IB, as a new emerging pharmacological target.

Vlachakis D, Pavlopoulou A, Roubelakis MG, Feidakis C, Anagnou NP, Kossida S.

Genomics. 2014 Jan;103(1):107-13. doi: 10.1016/j.ygeno.2013.11.008. Epub 2013 Dec 5.

22.

Sox2 suppression by miR-21 governs human mesenchymal stem cell properties.

Trohatou O, Zagoura D, Bitsika V, Pappa KI, Antsaklis A, Anagnou NP, Roubelakis MG.

Stem Cells Transl Med. 2014 Jan;3(1):54-68. doi: 10.5966/sctm.2013-0081. Epub 2013 Dec 4.

23.

Polymorphism Analysis of VSX1 and SOD1 Genes in Greek Patients with Keratoconus.

Moschos MM, Kokolakis N, Gazouli M, Chatziralli IP, Droutsas D, Anagnou NP, Ladas ID.

Ophthalmic Genet. 2015;36(3):213-7. doi: 10.3109/13816810.2013.843712.

PMID:
24099280
24.

Gene fusion analysis in the battle against the African endemic sleeping sickness.

Trimpalis P, Koumandou VL, Pliakou E, Anagnou NP, Kossida S.

PLoS One. 2013 Jul 17;8(7):e68854. doi: 10.1371/journal.pone.0068854. Print 2013.

25.

Towards more successful gene therapy clinical trials for β-thalassemia.

Drakopoulou E, Papanikolaou E, Georgomanoli M, Anagnou NP.

Curr Mol Med. 2013 Sep;13(8):1314-30. Review.

PMID:
23865429
26.

Characterization and comparative performance of lentiviral vector preparations concentrated by either one-step ultrafiltration or ultracentrifugation.

Papanikolaou E, Kontostathi G, Drakopoulou E, Georgomanoli M, Stamateris E, Vougas K, Vlahou A, Maloy A, Ware M, Anagnou NP.

Virus Res. 2013 Jul;175(1):1-11. doi: 10.1016/j.virusres.2013.03.015. Epub 2013 Apr 11.

PMID:
23583684
27.

Serum protein profile of Crohn's disease treated with infliximab.

Gazouli M, Anagnostopoulos AK, Papadopoulou A, Vaiopoulou A, Papamichael K, Mantzaris G, Theodoropoulos GE, Anagnou NP, Tsangaris GT.

J Crohns Colitis. 2013 Nov;7(10):e461-70. doi: 10.1016/j.crohns.2013.02.021. Epub 2013 Apr 3.

PMID:
23562004
28.

AF-MSCs fate can be regulated by culture conditions.

Zagoura DS, Trohatou O, Bitsika V, Makridakis M, Pappa KI, Vlahou A, Roubelakis MG, Anagnou NP.

Cell Death Dis. 2013 Apr 4;4:e571. doi: 10.1038/cddis.2013.93.

29.

Spindle shaped human mesenchymal stem/stromal cells from amniotic fluid promote neovascularization.

Roubelakis MG, Tsaknakis G, Pappa KI, Anagnou NP, Watt SM.

PLoS One. 2013;8(1):e54747. doi: 10.1371/journal.pone.0054747. Epub 2013 Jan 24.

30.

Circadian clock gene expression is impaired in gestational diabetes mellitus.

Pappa KI, Gazouli M, Anastasiou E, Iliodromiti Z, Antsaklis A, Anagnou NP.

Gynecol Endocrinol. 2013 Apr;29(4):331-5. doi: 10.3109/09513590.2012.743018. Epub 2013 Jan 17.

PMID:
23323702
31.

The major circadian pacemaker ARNT-like protein-1 (BMAL1) is associated with susceptibility to gestational diabetes mellitus.

Pappa KI, Gazouli M, Anastasiou E, Iliodromiti Z, Antsaklis A, Anagnou NP.

Diabetes Res Clin Pract. 2013 Feb;99(2):151-7. doi: 10.1016/j.diabres.2012.10.015. Epub 2012 Dec 1.

PMID:
23206673
32.

Transcription factor ATF-3 regulates allele variation phenotypes of the human SLC11A1 gene.

Taka S, Gazouli M, Politis PK, Pappa KI, Anagnou NP.

Mol Biol Rep. 2013 Mar;40(3):2263-71. doi: 10.1007/s11033-012-2289-1. Epub 2012 Nov 27.

PMID:
23187734
33.

Human amniotic fluid stem cells as an attractive tool for clinical applications.

Trohatou O, Anagnou NP, Roubelakis MG.

Curr Stem Cell Res Ther. 2013 Mar;8(2):125-32. Review.

PMID:
23140502
34.

Development of a quantum-dot-labelled magnetic immunoassay method for circulating colorectal cancer cell detection.

Gazouli M, Lyberopoulou A, Pericleous P, Rizos S, Aravantinos G, Nikiteas N, Anagnou NP, Efstathopoulos EP.

World J Gastroenterol. 2012 Aug 28;18(32):4419-26. doi: 10.3748/wjg.v18.i32.4419.

35.

Amniotic fluid and amniotic membrane stem cells: marker discovery.

Roubelakis MG, Trohatou O, Anagnou NP.

Stem Cells Int. 2012;2012:107836. doi: 10.1155/2012/107836. Epub 2012 Jun 3.

36.

Thiopurine methyltransferase genotype and thiopurine S-methyltransferase activity in Greek children with inflammatory bowel disease.

Gazouli M, Pachoula I, Panayotou I, Chouliaras G, Anagnou NP, Chroussos G, Roma E.

Ann Gastroenterol. 2012;25(3):249-253.

37.

The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia.

Drakopoulou E, Papanikolaou E, Anagnou NP.

Stem Cells Int. 2011;2011:987980. doi: 10.4061/2011/987980. Epub 2011 Nov 13.

38.

Profilin 1 is a potential biomarker for bladder cancer aggressiveness.

Zoidakis J, Makridakis M, Zerefos PG, Bitsika V, Esteban S, Frantzi M, Stravodimos K, Anagnou NP, Roubelakis MG, Sanchez-Carbayo M, Vlahou A.

Mol Cell Proteomics. 2012 Apr;11(4):M111.009449. doi: 10.1074/mcp.M111.009449. Epub 2011 Dec 8.

39.

Therapeutic potential of a distinct population of human amniotic fluid mesenchymal stem cells and their secreted molecules in mice with acute hepatic failure.

Zagoura DS, Roubelakis MG, Bitsika V, Trohatou O, Pappa KI, Kapelouzou A, Antsaklis A, Anagnou NP.

Gut. 2012 Jun;61(6):894-906. doi: 10.1136/gutjnl-2011-300908. Epub 2011 Oct 13.

PMID:
21997562
40.

Human amniotic fluid-derived mesenchymal stem cells as therapeutic vehicles: a novel approach for the treatment of bladder cancer.

Bitsika V, Roubelakis MG, Zagoura D, Trohatou O, Makridakis M, Pappa KI, Marini FC, Vlahou A, Anagnou NP.

Stem Cells Dev. 2012 May 1;21(7):1097-111. doi: 10.1089/scd.2011.0151. Epub 2011 Oct 11.

PMID:
21988169
41.

Expression profiling of vulvar carcinoma: clues for deranged extracellular matrix remodeling and effects on multiple signaling pathways combined with discrete patient subsets.

Pappa KI, Jacob-Hirsch J, Vlachos GD, Christodoulou I, Partsinevelos G, Amariglio N, Markaki S, Antsaklis A, Anagnou NP.

Transl Oncol. 2011 Oct;4(5):301-13. Epub 2011 Oct 1.

42.

The new self-inactivating lentiviral vector for thalassemia gene therapy combining two HPFH activating elements corrects human thalassemic hematopoietic stem cells.

Papanikolaou E, Georgomanoli M, Stamateris E, Panetsos F, Karagiorga M, Tsaftaridis P, Graphakos S, Anagnou NP.

Hum Gene Ther. 2012 Jan;23(1):15-31. doi: 10.1089/hum.2011.048. Epub 2011 Dec 5.

43.

Serotonin transporter and G protein beta 3 subunit gene polymorphisms in Greeks with irritable bowel syndrome.

Markoutsaki T, Karantanos T, Gazouli M, Anagnou NP, Ladas SD, Karamanolis DG.

Dig Dis Sci. 2011 Nov;56(11):3276-80. doi: 10.1007/s10620-011-1726-7. Epub 2011 May 11.

PMID:
21559741
44.

OCT4 spliced variant OCT4B1 is expressed in human colorectal cancer.

Gazouli M, Roubelakis MG, Theodoropoulos GE, Papailiou J, Vaiopoulou A, Pappa KI, Nikiteas N, Anagnou NP.

Mol Carcinog. 2012 Feb;51(2):165-73. doi: 10.1002/mc.20773. Epub 2011 Apr 7.

PMID:
21480394
45.

5-HT2A receptor gene polymorphisms and irritable bowel syndrome.

Markoutsaki T, Karantanos T, Gazouli M, Anagnou NP, Karamanolis DG.

J Clin Gastroenterol. 2011 Jul;45(6):514-7. doi: 10.1097/MCG.0b013e318205e13b.

PMID:
21325954
46.

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Colombel JF, Denson LA, De Vos M, Dubinsky M, Edwards C, Ellinghaus D, Fehrmann RS, Floyd JA, Florin T, Franchimont D, Franke L, Georges M, Glas J, Glazer NL, Guthery SL, Haritunians T, Hayward NK, Hugot JP, Jobin G, Laukens D, Lawrance I, Lémann M, Levine A, Libioulle C, Louis E, McGovern DP, Milla M, Montgomery GW, Morley KI, Mowat C, Ng A, Newman W, Ophoff RA, Papi L, Palmieri O, Peyrin-Biroulet L, Panés J, Phillips A, Prescott NJ, Proctor DD, Roberts R, Russell R, Rutgeerts P, Sanderson J, Sans M, Schumm P, Seibold F, Sharma Y, Simms LA, Seielstad M, Steinhart AH, Targan SR, van den Berg LH, Vatn M, Verspaget H, Walters T, Wijmenga C, Wilson DC, Westra HJ, Xavier RJ, Zhao ZZ, Ponsioen CY, Andersen V, Torkvist L, Gazouli M, Anagnou NP, Karlsen TH, Kupcinskas L, Sventoraityte J, Mansfield JC, Kugathasan S, Silverberg MS, Halfvarson J, Rotter JI, Mathew CG, Griffiths AM, Gearry R, Ahmad T, Brant SR, Chamaillard M, Satsangi J, Cho JH, Schreiber S, Daly MJ, Barrett JC, Parkes M, Annese V, Hakonarson H, Radford-Smith G, Duerr RH, Vermeire S, Weersma RK, Rioux JD.

Nat Genet. 2011 Mar;43(3):246-52. doi: 10.1038/ng.764. Epub 2011 Feb 6. Erratum in: Nat Genet. 2011 Sep;43(9):919.

47.

In vitro and in vivo properties of distinct populations of amniotic fluid mesenchymal progenitor cells.

Roubelakis MG, Bitsika V, Zagoura D, Trohatou O, Pappa KI, Makridakis M, Antsaklis A, Vlahou A, Anagnou NP.

J Cell Mol Med. 2011 Sep;15(9):1896-913. doi: 10.1111/j.1582-4934.2010.01180.x.

48.

Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.

Wilber A, Hargrove PW, Kim YS, Riberdy JM, Sankaran VG, Papanikolaou E, Georgomanoli M, Anagnou NP, Orkin SH, Nienhuis AW, Persons DA.

Blood. 2011 Mar 10;117(10):2817-26. doi: 10.1182/blood-2010-08-300723. Epub 2010 Dec 14.

49.

Variable effects of maternal and paternal-fetal contribution to the risk for preeclampsia combining GSTP1, eNOS, and LPL gene polymorphisms.

Pappa KI, Roubelakis M, Vlachos G, Marinopoulos S, Zissou A, Anagnou NP, Antsaklis A.

J Matern Fetal Neonatal Med. 2011 Apr;24(4):628-35. doi: 10.3109/14767058.2010.511351. Epub 2010 Sep 14.

50.

Major challenges for gene therapy of thalassemia and sickle cell disease.

Papanikolaou E, Anagnou NP.

Curr Gene Ther. 2010 Oct;10(5):404-12. Review.

PMID:
20712578

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