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Items: 15


Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma.

Chen L, Huang M, Plummer J, Pan J, Jiang YY, Yang Q, Silva TC, Gull N, Chen S, Ding LW, An O, Yang H, Cheng Y, Said JW, Doan N, Dinjens WN, Waters KM, Tuli R, Gayther SA, Klempner SJ, Berman BP, Meltzer SJ, Lin DC, Koeffler HP.

Gut. 2019 Aug 13. pii: gutjnl-2019-318325. doi: 10.1136/gutjnl-2019-318325. [Epub ahead of print]


The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia.

Tan SH, Leong WZ, Ngoc PCT, Tan TK, Bertulfo FC, Lim MC, An O, Li Z, Yeoh AEJ, Fullwood MJ, Tenen DG, Sanda T.

Blood. 2019 Jul 18;134(3):239-251. doi: 10.1182/blood.2018874503. Epub 2019 May 10.


Identification of a novel enhancer of CEBPE essential for granulocytic differentiation.

Shyamsunder P, Shanmugasundaram M, Mayakonda A, Dakle P, Teoh WW, Han L, Kanojia D, Lim MC, Fullwood M, An O, Yang H, Shi J, Hossain MZ, Madan V, Koeffler HP.

Blood. 2019 Jun 6;133(23):2507-2517. doi: 10.1182/blood.2018886077. Epub 2019 Apr 5.


Mutational and transcriptomic profiling of acute leukemia of ambiguous lineage reveals obscure but clinically important lineage bias.

Lao ZT, Ding LW, An O, Hattori N, Sun QY, Tan KT, Mayakonda A, Chuan WG, Madan V, Lin DC, Yang H, Koeffler HP.

Haematologica. 2019 May;104(5):e200-e203. doi: 10.3324/haematol.2018.202911. Epub 2018 Dec 4. No abstract available.


MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles.

Xuan Lin QX, Sian S, An O, Thieffry D, Jha S, Benoukraf T.

Nucleic Acids Res. 2019 Jan 8;47(D1):D145-D154. doi: 10.1093/nar/gky1005.


Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers.

Kumar R, Coronel L, Somalanka B, Raju A, Aning OA, An O, Ho YS, Chen S, Mak SY, Hor PY, Yang H, Lakshmanan M, Itoh H, Tan SY, Lim YK, Wong APC, Chew SH, Huynh TH, Goh BC, Lim CY, Tergaonkar V, Cheok CF.

Nat Commun. 2018 Sep 26;9(1):3931. doi: 10.1038/s41467-018-05805-1.


Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis.

Teoh PJ, An O, Chung TH, Chooi JY, Toh SHM, Fan S, Wang W, Koh BTH, Fullwood MJ, Ooi MG, de Mel S, Soekojo CY, Chen L, Ng SB, Yang H, Chng WJ.

Blood. 2018 Sep 20;132(12):1304-1317. doi: 10.1182/blood-2018-02-832576. Epub 2018 Jul 30.


Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer.

Hong H, An O, Chan THM, Ng VHE, Kwok HS, Lin JS, Qi L, Han J, Tay DJT, Tang SJ, Yang H, Song Y, Bellido Molias F, Tenen DG, Chen L.

Nucleic Acids Res. 2018 Sep 6;46(15):7953-7969. doi: 10.1093/nar/gky396.


Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma.

Xie JJ, Jiang YY, Jiang Y, Li CQ, Lim MC, An O, Mayakonda A, Ding LW, Long L, Sun C, Lin LH, Chen L, Wu JY, Wu ZY, Cao Q, Fang WK, Yang W, Soukiasian H, Meltzer SJ, Yang H, Fullwood M, Xu LY, Li EM, Lin DC, Koeffler HP.

Gastroenterology. 2018 Jun;154(8):2137-2151.e1. doi: 10.1053/j.gastro.2018.02.018. Epub 2018 Feb 15.


NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings.

An O, Dall'Olio GM, Mourikis TP, Ciccarelli FD.

Nucleic Acids Res. 2016 Jan 4;44(D1):D992-9. doi: 10.1093/nar/gkv1123. Epub 2015 Oct 29.


NCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomes.

An O, Pendino V, D'Antonio M, Ratti E, Gentilini M, Ciccarelli FD.

Database (Oxford). 2014 Mar 7;2014:bau015. doi: 10.1093/database/bau015. Print 2014.


Thyroid function of subjects with goitre and cretinism in an endemic goitre area of rural China after use of iodized salt.

Pang XP, An OY, Su TS, Hershman JM.

Acta Endocrinol (Copenh). 1988 Jul;118(3):444-8.


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