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Items: 14

1.

Immunological observations and transcriptomic analysis of trimester-specific full-term placentas from three Zika virus-infected women.

Lum FM, Narang V, Hue S, Chen J, McGovern N, Rajarethinam R, Tan JJ, Amrun SN, Chan YH, Lee CY, Chua TK, Yee WX, Yeo NK, Tan TC, Liu X, Haldenby S, Leo YS, Ginhoux F, Chan JK, Hiscox J, Chong CY, Ng LF.

Clin Transl Immunology. 2019 Nov 5;8(11):e01082. doi: 10.1002/cti2.1082. eCollection 2019.

2.

Novel differential linear B-cell epitopes to identify Zika and dengue virus infections in patients.

Amrun SN, Yee WX, Abu Bakar F, Lee B, Kam YW, Lum FM, Tan JJ, Lim VW, Watthanaworawit W, Ling C, Nosten F, Renia L, Leo YS, Ng LF.

Clin Transl Immunology. 2019 Jul 26;8(7):e1066. doi: 10.1002/cti2.1066. eCollection 2019.

3.

Mutating chikungunya virus non-structural protein produces potent live-attenuated vaccine candidate.

Chan YH, Teo TH, Utt A, Tan JJ, Amrun SN, Abu Bakar F, Yee WX, Becht E, Lee CY, Lee B, Rajarethinam R, Newell E, Merits A, Carissimo G, Lum FM, Ng LF.

EMBO Mol Med. 2019 Jun;11(6). pii: e10092. doi: 10.15252/emmm.201810092.

4.

ZIKV-Specific NS1 Epitopes as Serological Markers of Acute Zika Virus Infection.

Kam YW, Leite JA, Amrun SN, Lum FM, Yee WX, Bakar FA, Eng KE, Lye DC, Leo YS, Chong CY, Freitas ARR, Milanez GP, Proença-Modena JL, Rénia L, Costa FTM, Ng LFP; Zika-Unicamp Network.

J Infect Dis. 2019 Jun 19;220(2):203-212. doi: 10.1093/infdis/jiz092.

PMID:
30901054
5.

Multimodal assessments of Zika virus immune pathophysiological responses in marmosets.

Lum FM, Zhang W, Lim KC, Malleret B, Teo TH, Koh JJ, Lee KJ, Chua TK, Kam YW, Yee WX, Huen I, Tan JJL, Amrun SN, Prakash Kn B, Cozzone PJ, Renia L, Lee PTH, Ng LFP.

Sci Rep. 2018 Nov 20;8(1):17125. doi: 10.1038/s41598-018-35481-6.

6.

Plasmodium co-infection protects against chikungunya virus-induced pathologies.

Teo TH, Lum FM, Ghaffar K, Chan YH, Amrun SN, Tan JJL, Lee CYP, Chua TK, Carissimo G, Lee WWL, Claser C, Rajarethinam R, Rénia L, Ng LFP.

Nat Commun. 2018 Sep 25;9(1):3905. doi: 10.1038/s41467-018-06227-9.

7.

Longitudinal Study of Cellular and Systemic Cytokine Signatures to Define the Dynamics of a Balanced Immune Environment During Disease Manifestation in Zika Virus-Infected Patients.

Lum FM, Lye DCB, Tan JJL, Lee B, Chia PY, Chua TK, Amrun SN, Kam YW, Yee WX, Ling WP, Lim VWX, Pang VJX, Lee LK, Mok EWH, Chong CY, Leo YS, Ng LFP.

J Infect Dis. 2018 Jul 24;218(5):814-824. doi: 10.1093/infdis/jiy225.

8.

Inhibition of the Replication of Different Strains of Chikungunya Virus by 3-Aryl-[1,2,3]triazolo[4,5- d]pyrimidin-7(6 H)-ones.

Gómez-SanJuan A, Gamo AM, Delang L, Pérez-Sánchez A, Amrun SN, Abdelnabi R, Jacobs S, Priego EM, Camarasa MJ, Jochmans D, Leyssen P, Ng LFP, Querat G, Neyts J, Pérez-Pérez MJ.

ACS Infect Dis. 2018 Apr 13;4(4):605-619. doi: 10.1021/acsinfecdis.7b00219. Epub 2018 Feb 14.

PMID:
29406692
9.

Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections.

Kam YW, Lee CY, Teo TH, Howland SW, Amrun SN, Lum FM, See P, Kng NQ, Huber RG, Xu MH, Tan HL, Choo A, Maurer-Stroh S, Ginhoux F, Fink K, Wang CI, Ng LF, Rénia L.

JCI Insight. 2017 Apr 20;2(8). pii: 92428. doi: 10.1172/jci.insight.92428. eCollection 2017 Apr 20.

10.

Structural Optimizations of Thieno[3,2-b]pyrrole Derivatives for the Development of Metabolically Stable Inhibitors of Chikungunya Virus.

Ching KC, Tran TN, Amrun SN, Kam YW, Ng LF, Chai CL.

J Med Chem. 2017 Apr 13;60(7):3165-3186. doi: 10.1021/acs.jmedchem.7b00180. Epub 2017 Apr 4.

PMID:
28350454
11.

Fingolimod treatment abrogates chikungunya virus-induced arthralgia.

Teo TH, Chan YH, Lee WW, Lum FM, Amrun SN, Her Z, Rajarethinam R, Merits A, Rötzschke O, Rénia L, Ng LF.

Sci Transl Med. 2017 Feb 1;9(375). pii: eaal1333. doi: 10.1126/scitranslmed.aal1333.

PMID:
28148838
12.

Protein kinases C as potential host targets for the inhibition of chikungunya virus replication.

Abdelnabi R, Amrun SN, Ng LF, Leyssen P, Neyts J, Delang L.

Antiviral Res. 2017 Mar;139:79-87. doi: 10.1016/j.antiviral.2016.12.020. Epub 2016 Dec 27.

PMID:
28039020
13.

Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice.

Lee WW, Teo TH, Lum FM, Andiappan AK, Amrun SN, Rénia L, Rötzschke O, Ng LF.

Sci Rep. 2016 Nov 25;6:37603. doi: 10.1038/srep37603.

14.

The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling.

Varghese FS, Thaa B, Amrun SN, Simarmata D, Rausalu K, Nyman TA, Merits A, McInerney GM, Ng LFP, Ahola T.

J Virol. 2016 Oct 14;90(21):9743-9757. doi: 10.1128/JVI.01382-16. Print 2016 Nov 1.

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