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Items: 24

1.

Machine learning-powered antibiotics phenotypic drug discovery.

Zoffmann S, Vercruysse M, Benmansour F, Maunz A, Wolf L, Blum Marti R, Heckel T, Ding H, Truong HH, Prummer M, Schmucki R, Mason CS, Bradley K, Jacob AI, Lerner C, Araujo Del Rosario A, Burcin M, Amrein KE, Prunotto M.

Sci Rep. 2019 Mar 21;9(1):5013. doi: 10.1038/s41598-019-39387-9.

2.

White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

Moisan A, Lee YK, Zhang JD, Hudak CS, Meyer CA, Prummer M, Zoffmann S, Truong HH, Ebeling M, Kiialainen A, Gérard R, Xia F, Schinzel RT, Amrein KE, Cowan CA.

Nat Cell Biol. 2015 Jan;17(1):57-67. doi: 10.1038/ncb3075. Epub 2014 Dec 8.

3.

THP-1 Macrophages and SGBS Adipocytes - A New Human in vitro Model System of Inflamed Adipose Tissue.

Keuper M, Dzyakanchuk A, Amrein KE, Wabitsch M, Fischer-Posovszky P.

Front Endocrinol (Lausanne). 2011 Dec 14;2:89. doi: 10.3389/fendo.2011.00089. eCollection 2011.

4.

11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose.

Dzyakanchuk AA, Balázs Z, Nashev LG, Amrein KE, Odermatt A.

Mol Cell Endocrinol. 2009 Mar 25;301(1-2):137-41. doi: 10.1016/j.mce.2008.08.009. Epub 2008 Aug 20.

PMID:
18778749
5.

An improved vector system for insertional gene inactivation inspired by the tmRNA-tagging system of S. pneumoniae.

Molnos J, Lange R, Amrein KE.

J Microbiol Methods. 2000 Oct;42(2):197-201.

PMID:
11018276
6.

Microarray-based identification of a novel Streptococcus pneumoniae regulon controlled by an autoinduced peptide.

de Saizieu A, Gardès C, Flint N, Wagner C, Kamber M, Mitchell TJ, Keck W, Amrein KE, Lange R.

J Bacteriol. 2000 Sep;182(17):4696-703.

7.

Domain organization and molecular characterization of 13 two-component systems identified by genome sequencing of Streptococcus pneumoniae.

Lange R, Wagner C, de Saizieu A, Flint N, Molnos J, Stieger M, Caspers P, Kamber M, Keck W, Amrein KE.

Gene. 1999 Sep 3;237(1):223-34.

PMID:
10524254
8.

Csk-mediated phosphorylation of substrates is regulated by substrate tyrosine phosphorylation.

Amrein KE, Molnos J, zur Hausen JD, Flint N, Takacs B, Burn P.

Farmaco. 1998 Apr;53(4):266-72.

PMID:
9658584
9.

Co-localization of Fyn with CD3 complex, CD45 or CD28 depends on different mechanisms.

zur Hausen JD, Burn P, Amrein KE.

Eur J Immunol. 1997 Oct;27(10):2643-9.

PMID:
9368621
10.

Protein-tyrosine phosphatases PTP1B and syp are modulators of insulin-stimulated translocation of GLUT4 in transfected rat adipose cells.

Chen H, Wertheimer SJ, Lin CH, Katz SL, Amrein KE, Burn P, Quon MJ.

J Biol Chem. 1997 Mar 21;272(12):8026-31.

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Mapping of the p56lck-mediated phosphorylation of GAP and analysis of its influence on p21ras-GTPase activity in vitro.

Amrein KE, Panholzer B, Molnos J, Flint NA, Scheffler J, Lahm HW, Bannwarth W, Burn P.

Biochim Biophys Acta. 1994 Jul 21;1222(3):441-6.

PMID:
8038213
13.
14.

Identification of a signaling complex involving CD2, zeta chain and p59fyn in T lymphocytes.

Gassmann M, Amrein KE, Flint NA, Schraven B, Burn P.

Eur J Immunol. 1994 Jan;24(1):139-44.

PMID:
7912674
15.

The Src homology 2 domain of the protein-tyrosine kinase p56lck mediates both intermolecular and intramolecular interactions.

Amrein KE, Panholzer B, Flint NA, Bannwarth W, Burn P.

Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10285-9.

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The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity.

Bergman M, Mustelin T, Oetken C, Partanen J, Flint NA, Amrein KE, Autero M, Burn P, Alitalo K.

EMBO J. 1992 Aug;11(8):2919-24.

20.

Ras GTPase-activating protein: a substrate and a potential binding protein of the protein-tyrosine kinase p56lck.

Amrein KE, Flint N, Panholzer B, Burn P.

Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3343-6.

21.

Protein tyrosine kinase p59fyn is associated with the T cell receptor-CD3 complex in functional human lymphocytes.

Gassmann M, Guttinger M, Amrein KE, Burn P.

Eur J Immunol. 1992 Jan;22(1):283-6.

PMID:
1530920
22.

Short related sequences in the cytoplasmic domains of CD4 and CD8 mediate binding to the amino-terminal domain of the p56lck tyrosine protein kinase.

Shaw AS, Chalupny J, Whitney JA, Hammond C, Amrein KE, Kavathas P, Sefton BM, Rose JK.

Mol Cell Biol. 1990 May;10(5):1853-62.

23.

The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain.

Shaw AS, Amrein KE, Hammond C, Stern DF, Sefton BM, Rose JK.

Cell. 1989 Nov 17;59(4):627-36.

PMID:
2582490

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