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Development and Validation of Hepamet Fibrosis Scoring System A Simple, Noninvasive Test to Identify Patients With Nonalcoholic Fatty Liver Disease With Advanced Fibrosis.

Ampuero J, Pais R, Aller R, Gallego-Durán R, Crespo J, García-Monzón C, Boursier J, Vilar E, Petta S, Ming-Hua Z, Escudero D, Calleja JL, Aspichueta P, Diago M, Rosales JM, Caballería J, Gómez-Camarero J, Lo Iacono O, Benlloch S, Albillos A, Turnes J, Banales JM, Ratziu V, Romero-Gómez M; HEPAmet Registry.

Clin Gastroenterol Hepatol. 2019 Jun 11. pii: S1542-3565(19)30602-0. doi: 10.1016/j.cgh.2019.05.051. [Epub ahead of print]


Sofosbuvir/velpatasvir for 12 weeks in hepatitis C virus-infected patients with end-stage renal disease undergoing dialysis.

Borgia SM, Dearden J, Yoshida EM, Shafran SD, Brown A, Ben-Ari Z, Cramp ME, Cooper C, Foxton M, Rodriguez CF, Esteban R, Hyland R, Lu S, Kirby BJ, Meng A, Markova S, Dvory-Sobol H, Osinusi AO, Bruck R, Ampuero J, Ryder SD, Agarwal K, Fox R, Shaw D, Haider S, Willems B, Lurie Y, Calleja JL, Gane EJ.

J Hepatol. 2019 Jun 11. pii: S0168-8278(19)30343-5. doi: 10.1016/j.jhep.2019.05.028. [Epub ahead of print]


Metabolic characterization of two different non-alcoholic fatty liver disease pre-clinical mouse models.

Gallego-Durán R, Álvarez-Amor L, Gil-Gómez A, Rojas Á, Muñoz-Hernández R, Cádernas-García A, Maya-Miles D, Montero-Vallejo R, Gato S, Sánchez Torrijos Y, Ampuero J, Martín F, Romero-Gómez M.

Rev Esp Enferm Dig. 2019 Apr;111(4):301-307. doi: 10.17235/reed.2019.6083/2018.


Dynamic viability of the 2016 Mw 7.8 Kaikōura earthquake cascade on weak crustal faults.

Ulrich T, Gabriel AA, Ampuero JP, Xu W.

Nat Commun. 2019 Mar 14;10(1):1213. doi: 10.1038/s41467-019-09125-w.


Analysis of the burden and variability in the management of NAFLD patients in the clinical practice: unifying the required criteria.

Sánchez-Torrijos Y, Ampuero J, Pérez Palacios D, Gallego-Durán R, Romero-Gómez M.

Rev Esp Enferm Dig. 2019 Apr;111(4):270-274. doi: 10.17235/reed.2019.6088/2018.


Higher levels of serum uric acid influences hepatic damage in patients with non-alcoholic fatty liver disease (NAFLD).

Fernández Rodríguez CM, Aller R, Gutiérrez García ML, Ampuero J, Gómez-Camarero J, Martín-Mateos RMª, Burgos-Santamaría D, Rosales JM, Aspichueta P, Buque X, Latorre M, Andrade RJ, Hernández-Guerra M, Romero-Gómez M.

Rev Esp Enferm Dig. 2019 Apr;111(4):264-269. doi: 10.17235/reed.2019.5965/2018.


Usefulness of bioelectrical impedance analysis for monitoring patients with refractory ascites.

Ontanilla-Clavijo G, Ampuero J, Borreguero S, Rosell J, Romero-Gómez M.

Rev Esp Enferm Dig. 2019 Mar;111(3):223-227. doi: 10.17235/reed.2018.5634/2018.


The effects of metabolic status on non-alcoholic fatty liver disease-related outcomes, beyond the presence of obesity.

Ampuero J, Aller R, Gallego-Durán R, Banales JM, Crespo J, García-Monzón C, Pareja MJ, Vilar-Gómez E, Caballería J, Escudero-García D, Gomez-Camarero J, Calleja JL, Latorre M, Albillos A, Salmeron J, Aspichueta P, Lo Iacono O, Francés R, Benlloch S, Fernández-Rodríguez C, García-Samaniego J, Estévez P, Andrade RJ, Turnes J, Romero-Gómez M; HEPAmet Registry.

Aliment Pharmacol Ther. 2018 Dec;48(11-12):1260-1270. doi: 10.1111/apt.15015. Epub 2018 Oct 23.


Peer-to-Peer Sessions in Primary Care to Improve the Hepatitis B Detection Rate in Seville, Spain.

Otero MÁ, Liu CH, Ampuero J, Llorca R, Vargas-Romero M, Romero-Gómez M.

Ann Hepatol. 2018 Aug 24;17(5):864-870. doi: 10.5604/01.3001.0012.3162.


miRNAs in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis.

Liu CH, Ampuero J, Gil-Gómez A, Montero-Vallejo R, Rojas Á, Muñoz-Hernández R, Gallego-Durán R, Romero-Gómez M.

J Hepatol. 2018 Dec;69(6):1335-1348. doi: 10.1016/j.jhep.2018.08.008. Epub 2018 Aug 22.


First Report of Trypanosoma cruzi Infection in Salivary Gland of Bats from the Peruvian Amazon.

Villena FE, Gomez-Puerta LA, Jhonston EJ, Del Alcazar OM, Maguiña JL, Albujar C, Laguna-Torres VA, Recuenco SE, Ballard SB, Ampuero JS.

Am J Trop Med Hyg. 2018 Sep;99(3):723-728. doi: 10.4269/ajtmh.17-0816. Epub 2018 Jul 12.


Diagnostic accuracy of SCCA and SCCA-IgM for hepatocellular carcinoma: A meta-analysis.

Liu CH, Gil-Gómez A, Ampuero J, Romero-Gómez M.

Liver Int. 2018 Oct;38(10):1820-1831. doi: 10.1111/liv.13867. Epub 2018 May 22.


Human Antibody Responses to Emerging Mayaro Virus and Cocirculating Alphavirus Infections Examined by Using Structural Proteins from Nine New and Old World Lineages.

Smith JL, Pugh CL, Cisney ED, Keasey SL, Guevara C, Ampuero JS, Comach G, Gomez D, Ochoa-Diaz M, Hontz RD, Ulrich RG.

mSphere. 2018 Mar 21;3(2). pii: e00003-18. doi: 10.1128/mSphere.00003-18. eCollection 2018 Mar-Apr.


Metformin modifies glutamine metabolism in an in vitro and in vivo model of hepatic encephalopathy.

Gil-GÓmez A, Gómez-Sotelo AI, Ranchal I, Rojas Á, García-Valdecasas M, Muñoz-Hernández R, Gallego-Durán R, Ampuero J, Romero Gómez M.

Rev Esp Enferm Dig. 2018 Jul;110(7):427-433. doi: 10.17235/reed.2018.5004/2017.


Editorial: looking for patients at risk of cirrhosis in the general population-many needles in a haystack.

Ampuero J, Romero-Gómez M.

Aliment Pharmacol Ther. 2018 Mar;47(5):692-694. doi: 10.1111/apt.14517. No abstract available.


Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy.

Del Campo JA, García-Valdecasas M, Gil-Gómez A, Rojas Á, Gallego P, Ampuero J, Gallego-Durán R, Pastor H, Grande L, Padillo FJ, Muntané J, Romero-Gómez M.

PLoS One. 2018 Jan 31;13(1):e0191805. doi: 10.1371/journal.pone.0191805. eCollection 2018.


Duration of the acute hepatic encephalopathy episode determines survival in cirrhotic patients.

Ventura-Cots M, Carmona I, Moreno C, Ampuero J, Simón-Talero M, Sanpedro F, Les I, Romero-Gómez M, Genescà J.

Therap Adv Gastroenterol. 2017 Nov 26;11:1756283X17743419. doi: 10.1177/1756283X17743419. eCollection 2018.


Induced seismicity provides insight into why earthquake ruptures stop.

Galis M, Ampuero JP, Mai PM, Cappa F.

Sci Adv. 2017 Dec 20;3(12):eaap7528. doi: 10.1126/sciadv.aap7528. eCollection 2017 Dec.


Impact of comorbidities on patient outcomes after interferon-free therapy-induced viral eradication in hepatitis C.

Ampuero J, Jimeno C, Quiles R, Rosales JM, Llerena S, Palomo N, Cordero P, Serrano FJ, Urquijo JJ, Moreno-Planas JM, Ontanilla G, Hernández M, Ortega-Alonso A, Maraver M, Bonacci M, Rojas Á, Figueruela B, Forns X, Andrade RJ, Calleja JL, Diago M, Carmona I, de la Mata M, Buti M, Crespo J, Pascasio JM, Navarro JM, Salmerón J, Romero-Gómez M.

J Hepatol. 2018 May;68(5):940-948. doi: 10.1016/j.jhep.2017.12.019. Epub 2017 Dec 28.


The transmission dynamics and diversity of human metapneumovirus in Peru.

Pollett S, Trovão NS, Tan Y, Eden JS, Halpin RA, Bera J, Das SR, Wentworth D, Ocaña V, Mendocilla SM, Álvarez C, Calisto ME, Garcia J, Halsey E, Ampuero JS, Nelson MI, Leguia M.

Influenza Other Respir Viruses. 2018 Jul;12(4):508-513. doi: 10.1111/irv.12537. Epub 2018 Mar 30.


Observations and modeling of the elastogravity signals preceding direct seismic waves.

Vallée M, Ampuero JP, Juhel K, Bernard P, Montagner JP, Barsuglia M.

Science. 2017 Dec 1;358(6367):1164-1168. doi: 10.1126/science.aao0746.


The hidden simplicity of subduction megathrust earthquakes.

Meier MA, Ampuero JP, Heaton TH.

Science. 2017 Sep 22;357(6357):1277-1281. doi: 10.1126/science.aan5643.


Solving doubts about L-ornithine L-aspartate for overt hepatic encephalopathy: Whom and how to treat.

Amodio P, Ampuero J.

Hepatology. 2018 Feb;67(2):476-478. doi: 10.1002/hep.29530. Epub 2018 Jan 1. No abstract available.


New therapeutic perspectives in non-alcoholic steatohepatitis.

Ampuero J, Sánchez-Torrijos Y, Aguilera V, Bellido F, Romero-Gómez M.

Gastroenterol Hepatol. 2018 Feb;41(2):128-142. doi: 10.1016/j.gastrohep.2017.07.006. Epub 2017 Sep 2. Review. English, Spanish.


Minimal hepatic encephalopathy identifies patients at risk of faster cirrhosis progression.

Ampuero J, Montoliú C, Simón-Talero M, Aguilera V, Millán R, Márquez C, Jover R, Rico MC, Sendra C, Serra MÁ, Romero-Gómez M.

J Gastroenterol Hepatol. 2018 Mar;33(3):718-725. doi: 10.1111/jgh.13917.


Serologic Evidence of Scrub Typhus in the Peruvian Amazon.

Kocher C, Jiang J, Morrison AC, Castillo R, Leguia M, Loyola S, Ampuero JS, Cespedes M, Halsey ES, Bausch DG, Richards AL.

Emerg Infect Dis. 2017 Aug;23(8):1389-1391. doi: 10.3201/eid2308.170050.


Cardiovascular assessment in liver transplant for non-alcoholic steatohepatitis patients: What we do, what we should do.

Sanchez-Torrijos Y, Ampuero J, Romero-Gómez M.

World J Hepatol. 2017 May 28;9(15):697-703. doi: 10.4254/wjh.v9.i15.697. Review.


Acute-on-chronic liver failure: a time to step forward.

Ampuero J.

Rev Esp Enferm Dig. 2017 Jun;109(6):397-398. doi: 10.17235/reed.2017.5054/2017.


Genetic diversity of armored scales (Hemiptera: Diaspididae) and soft scales (Hemiptera: Coccidae) in Chile.

Amouroux P, Crochard D, Germain JF, Correa M, Ampuero J, Groussier G, Kreiter P, Malausa T, Zaviezo T.

Sci Rep. 2017 May 17;7(1):2014. doi: 10.1038/s41598-017-01997-6.


Adding access blood flow surveillance reduces thrombosis and improves arteriovenous fistula patency: a randomized controlled trial.

Aragoncillo I, Abad S, Caldés S, Amézquita Y, Vega A, Cirugeda A, Moratilla C, Ibeas J, Roca-Tey R, Fernández C, Macías N, Quiroga B, Blanco A, Villaverde M, Ruiz C, Martín B, Ruiz AM, Ampuero J, de Alvaro F, López-Gómez JM.

J Vasc Access. 2017 Jul 14;18(4):352-358. doi: 10.5301/jva.5000700. Epub 2017 Apr 20.


Real-World Effectiveness and Safety of Oral Combination Antiviral Therapy for Hepatitis C Virus Genotype 4 Infection.

Crespo J, Calleja JL, Fernández I, Sacristan B, Ruiz-Antorán B, Ampuero J, Hernández-Conde M, García-Samaniego J, Gea F, Buti M, Cabezas J, Lens S, Morillas RM, Salcines JR, Pascasio JM, Turnes J, Sáez-Royuela F, Arenas J, Rincón D, Prieto M, Jorquera F, Sanchez Ruano JJ, Navascués CA, Molina E, Moya AG, Moreno-Planas JM; Spanish Group for the Study of the Use of Direct-acting Drugs Hepatitis C Collaborating Group.

Clin Gastroenterol Hepatol. 2017 Jun;15(6):945-949.e1. doi: 10.1016/j.cgh.2017.02.020. Epub 2017 Feb 24.


Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort.

Calleja JL, Crespo J, Rincón D, Ruiz-Antorán B, Fernandez I, Perelló C, Gea F, Lens S, García-Samaniego J, Sacristán B, García-Eliz M, Llerena S, Pascasio JM, Turnes J, Torras X, Morillas RM, Llaneras J, Serra MA, Diago M, Rodriguez CF, Ampuero J, Jorquera F, Simon MA, Arenas J, Navascues CA, Bañares R, Muñoz R, Albillos A, Mariño Z; Spanish Group for the Study of the Use of Direct-acting Drugs Hepatitis C Collaborating Group.

J Hepatol. 2017 Jun;66(6):1138-1148. doi: 10.1016/j.jhep.2017.01.028. Epub 2017 Feb 9.


Low phase angle is associated with the development of hepatic encephalopathy in patients with cirrhosis.

Ruiz-Margáin A, Macías-Rodríguez RU, Ampuero J, Cubero FJ, Chi-Cervera L, Ríos-Torres SL, Duarte-Rojo A, Espinosa-Cuevas Á, Romero-Gómez M, Torre A.

World J Gastroenterol. 2016 Dec 7;22(45):10064-10070. doi: 10.3748/wjg.v22.i45.10064.


Ruminococcus gnavus infection of a metal-on-metal hip arthroplasty resembling a pseudo-tumour in a 72 year-old woman with no intestinal symptoms.

Fernández-Caso B, Domingo García D, Domingo LC, Ampuero JC.

Enferm Infecc Microbiol Clin. 2017 Oct;35(8):542-543. doi: 10.1016/j.eimc.2016.11.002. Epub 2016 Dec 12. English, Spanish. No abstract available.


Effectiveness and safety of sofosbuvir-based regimens plus an NS5A inhibitor for patients with HCV genotype 3 infection and cirrhosis. Results of a multicenter real-life cohort.

Alonso S, Riveiro-Barciela M, Fernandez I, Rincón D, Real Y, Llerena S, Gea F, Olveira A, Fernandez-Carrillo C, Polo B, Carrión JA, Gómez A, Devesa MJ, Baliellas C, Castro Á, Ampuero J, Granados R, Pascasio JM, Rubín A, Salmeron J, Badia E, Planas JM, Lens S, Turnes J, Montero JL, Buti M, Esteban R, Fernández-Rodríguez CM.

J Viral Hepat. 2017 Apr;24(4):304-311. doi: 10.1111/jvh.12648. Epub 2016 Dec 9.


Prompt gravity signal induced by the 2011 Tohoku-Oki earthquake.

Montagner JP, Juhel K, Barsuglia M, Ampuero JP, Chassande-Mottin E, Harms J, Whiting B, Bernard P, Clévédé E, Lognonné P.

Nat Commun. 2016 Nov 22;7:13349. doi: 10.1038/ncomms13349.


Localized seismic deformation in the upper mantle revealed by dense seismic arrays.

Inbal A, Ampuero JP, Clayton RW.

Science. 2016 Oct 7;354(6308):88-92.


Enterovirus-71 genotype C isolated in Peru between 2006 and 2009.

Huaman JL, Carrion G, Ampuero JS, Ocaña V, Laguna-Torres VA, Hontz RD.

J Clin Virol. 2016 Dec;85:40-43. doi: 10.1016/j.jcv.2016.10.023. Epub 2016 Nov 3.


Molecular epidemiology of coxsackievirus A16 strains from four sentinel surveillance sites in Peru.

Carrion G, Huaman JL, Silva M, Ampuero JS, Paz I, Ocaña VR, Laguna-Torres VA, Hontz RD.

Int J Infect Dis. 2016 Nov;52:83-85. doi: 10.1016/j.ijid.2016.10.003. Epub 2016 Oct 6.


Role of assessing liver fibrosis in management of chronic hepatitis C virus infection.

Carmona I, Cordero P, Ampuero J, Rojas A, Romero-Gómez M.

Clin Microbiol Infect. 2016 Oct;22(10):839-845. doi: 10.1016/j.cmi.2016.09.017. Epub 2016 Sep 24. Review.


New technologies - new insights into the pathogenesis of hepatic encephalopathy.

Baker L, Lanz B, Andreola F, Ampuero J, Wijeyesekera A, Holmes E, Deutz N.

Metab Brain Dis. 2016 Dec;31(6):1259-1267. Epub 2016 Sep 30. Review.


Pharmacogenetics of ribavirin-induced anemia in hepatitis C.

Ampuero J, Romero-Gómez M.

Pharmacogenomics. 2016 Sep;17(14):1587-94. doi: 10.2217/pgs.16.28. Epub 2016 Aug 22.


Imaging biomarkers for steatohepatitis and fibrosis detection in non-alcoholic fatty liver disease.

Gallego-Durán R, Cerro-Salido P, Gomez-Gonzalez E, Pareja MJ, Ampuero J, Rico MC, Aznar R, Vilar-Gomez E, Bugianesi E, Crespo J, González-Sánchez FJ, Aparcero R, Moreno I, Soto S, Arias-Loste MT, Abad J, Ranchal I, Andrade RJ, Calleja JL, Pastrana M, Iacono OL, Romero-Gómez M.

Sci Rep. 2016 Aug 12;6:31421. doi: 10.1038/srep31421.


Rickettsial Disease in the Peruvian Amazon Basin.

Kocher C, Morrison AC, Leguia M, Loyola S, Castillo RM, Galvez HA, Astete H, Flores-Mendoza C, Ampuero JS, Bausch DG, Halsey ES, Cespedes M, Zevallos K, Jiang J, Richards AL.

PLoS Negl Trop Dis. 2016 Jul 14;10(7):e0004843. doi: 10.1371/journal.pntd.0004843. eCollection 2016 Jul.


Lactulose reduces bacterial DNA translocation, which worsens neurocognitive shape in cirrhotic patients with minimal hepatic encephalopathy.

Moratalla A, Ampuero J, Bellot P, Gallego-Durán R, Zapater P, Roger M, Figueruela B, Martínez-Moreno B, González-Navajas JM, Such J, Romero-Gómez M, Francés R.

Liver Int. 2017 Feb;37(2):212-223. doi: 10.1111/liv.13200. Epub 2016 Jul 29.


Near-trench slip potential of megaquakes evaluated from fault properties and conditions.

Hirono T, Tsuda K, Tanikawa W, Ampuero JP, Shibazaki B, Kinoshita M, Mori JJ.

Sci Rep. 2016 Jun 20;6:28184. doi: 10.1038/srep28184.


Hepatitis C virus genotype 3: Meta-analysis on sustained virologic response rates with currently available treatment options.

Ampuero J, Reddy KR, Romero-Gomez M.

World J Gastroenterol. 2016 Jun 14;22(22):5285-92. doi: 10.3748/wjg.v22.i22.5285. Review.


Case Report: Acute-on-Chronic Liver Failure: Making the Diagnosis between Infection and Acute Alcoholic Hepatitis.

Sendra C, Ampuero J, Gallego ÁG, Sousa JM, Jiménez MS, Romero-Gómez M.

Semin Liver Dis. 2016 May;36(2):181-6. doi: 10.1055/s-0036-1583203. Epub 2016 May 12.


Oxidized low-density lipoprotein antibodies/high-density lipoprotein cholesterol ratio is linked to advanced non-alcoholic fatty liver disease lean patients.

Ampuero J, Ranchal I, Gallego-Durán R, Pareja MJ, Del Campo JA, Pastor-Ramírez H, Rico MC, Picón R, Pastor L, García-Monzón C, Andrade R, Romero-Gómez M.

J Gastroenterol Hepatol. 2016 Sep;31(9):1611-8. doi: 10.1111/jgh.13335.


Hepatitis C Virus: Current and Evolving Treatments for Genotypes 2 and 3.

Ampuero J, Romero-Gómez M.

Gastroenterol Clin North Am. 2015 Dec;44(4):845-57. doi: 10.1016/j.gtc.2015.07.009. Epub 2015 Aug 11. Review.


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