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Items: 1 to 50 of 107

1.

A new evolutionary model for the vertebrate actin family including two novel groups.

Witjes L, Van Troys M, Vandekerckhove J, Vandepoele K, Ampe C.

Mol Phylogenet Evol. 2019 Sep 24;141:106632. doi: 10.1016/j.ympev.2019.106632. [Epub ahead of print]

PMID:
31560986
2.

Furan Cross-Linking Technology for Investigating GPCR-Ligand Interactions.

Van Troys M, Vannecke W, Ampe C, Madder A.

Methods Mol Biol. 2019;1947:81-102. doi: 10.1007/978-1-4939-9121-1_5.

PMID:
30969412
3.

Surveillance of Myelodysplastic Syndrome via Migration Analyses of Blood Neutrophils: A Potential Prognostic Tool.

Schuster M, Moeller M, Bornemann L, Bessen C, Sobczak C, Schmitz S, Witjes L, Kruithoff K, Kohn C, Just O, Kündgen A, Pundt N, Pelzer B, Ampe C, Van Troys M, Nusch A, Haas R, Germing U, Martens L, Jöckel KH, Gunzer M.

J Immunol. 2018 Dec 15;201(12):3546-3557. doi: 10.4049/jimmunol.1801071. Epub 2018 Nov 16.

PMID:
30446567
4.

Combination of EGFR Inhibitor Lapatinib and MET Inhibitor Foretinib Inhibits Migration of Triple Negative Breast Cancer Cell Lines.

Simiczyjew A, Dratkiewicz E, Van Troys M, Ampe C, Styczeń I, Nowak D.

Cancers (Basel). 2018 Sep 17;10(9). pii: E335. doi: 10.3390/cancers10090335.

5.

Analysis of Invasion Dynamics of Matrix-Embedded Cells in a Multisample Format.

Van Troys M, Masuzzo P, Huyck L, Bakkali K, Waterschoot D, Martens L, Ampe C.

Methods Mol Biol. 2018;1749:79-117. doi: 10.1007/978-1-4939-7701-7_9.

PMID:
29525993
6.

An emerging link between LIM domain proteins and nuclear receptors.

Sala S, Ampe C.

Cell Mol Life Sci. 2018 Jun;75(11):1959-1971. doi: 10.1007/s00018-018-2774-3. Epub 2018 Feb 10. Review.

PMID:
29428964
7.

Cross-Linking Furan-Modified Kisspeptin-10 to the KISS Receptor.

Vannecke W, Ampe C, Van Troys M, Beltramo M, Madder A.

ACS Chem Biol. 2017 Aug 18;12(8):2191-2200. doi: 10.1021/acschembio.7b00396. Epub 2017 Jul 17.

PMID:
28714670
8.

The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions.

Sala S, Catillon M, Hadzic E, Schaffner-Reckinger E, Van Troys M, Ampe C.

PLoS One. 2017 May 18;12(5):e0177879. doi: 10.1371/journal.pone.0177879. eCollection 2017.

9.

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

Sala S, Van Troys M, Medves S, Catillon M, Timmerman E, Staes A, Schaffner-Reckinger E, Gevaert K, Ampe C.

J Proteome Res. 2017 May 5;16(5):2054-2071. doi: 10.1021/acs.jproteome.7b00034. Epub 2017 Apr 20.

PMID:
28378594
10.

An end-to-end software solution for the analysis of high-throughput single-cell migration data.

Masuzzo P, Huyck L, Simiczyjew A, Ampe C, Martens L, Van Troys M.

Sci Rep. 2017 Feb 13;7:42383. doi: 10.1038/srep42383.

11.

Mammalian Actins: Isoform-Specific Functions and Diseases.

Ampe C, Van Troys M.

Handb Exp Pharmacol. 2017;235:1-37. doi: 10.1007/164_2016_43. Review.

PMID:
27757757
12.

Active invadopodia of mesenchymally migrating cancer cells contain both β and γ cytoplasmic actin isoforms.

Simiczyjew A, Mazur AJ, Ampe C, Malicka-Błaszkiewicz M, van Troys M, Nowak D.

Exp Cell Res. 2015 Dec 10;339(2):206-19. doi: 10.1016/j.yexcr.2015.11.003. Epub 2015 Nov 5.

PMID:
26548725
13.

Delineating the Tes Interaction Site in Zyxin and Studying Cellular Effects of Its Disruption.

Hadzic E, Catillon M, Halavatyi A, Medves S, Van Troys M, Moes M, Baird MA, Davidson MW, Schaffner-Reckinger E, Ampe C, Friederich E.

PLoS One. 2015 Oct 28;10(10):e0140511. doi: 10.1371/journal.pone.0140511. eCollection 2015.

14.

Taking Aim at Moving Targets in Computational Cell Migration.

Masuzzo P, Van Troys M, Ampe C, Martens L.

Trends Cell Biol. 2016 Feb;26(2):88-110. doi: 10.1016/j.tcb.2015.09.003. Epub 2015 Nov 10. Review.

15.

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure.

Vandewynckel YP, Laukens D, Devisscher L, Paridaens A, Bogaerts E, Verhelst X, Van den Bussche A, Raevens S, Van Steenkiste C, Van Troys M, Ampe C, Descamps B, Vanhove C, Govaere O, Geerts A, Van Vlierberghe H.

Oncotarget. 2015 Sep 29;6(29):28011-25. doi: 10.18632/oncotarget.4377.

16.

An open data ecosystem for cell migration research.

Masuzzo P, Martens L; 2014 Cell Migration Workshop Participants, Ampe C, Anderson KI, Barry J, De Wever O, Debeir O, Decaestecker C, Dolznig H, Friedl P, Gaggioli C, Geiger B, Goldberg IG, Horn E, Horwitz R, Kam Z, Le Dévédec SE, Vignjevic DM, Moore J, Olivo-Marin JC, Sahai E, Sansone SA, Sanz-Moreno V, Strömblad S, Swedlow J, Textor J, Van Troys M, Zantl R.

Trends Cell Biol. 2015 Feb;25(2):55-8. doi: 10.1016/j.tcb.2014.11.005. Epub 2014 Dec 5.

PMID:
25484346
17.

Development of land use regression models for elemental, organic carbon, PAH, and hopanes/steranes in 10 ESCAPE/TRANSPHORM European study areas.

Jedynska A, Hoek G, Wang M, Eeftens M, Cyrys J, Keuken M, Ampe C, Beelen R, Cesaroni G, Forastiere F, Cirach M, de Hoogh K, De Nazelle A, Nystad W, Declercq C, Eriksen KT, Dimakopoulou K, Lanki T, Meliefste K, Nieuwenhuijsen MJ, Yli-Tuomi T, Raaschou-Nielsen O, Brunekreef B, Kooter IM.

Environ Sci Technol. 2014 Dec 16;48(24):14435-44. doi: 10.1021/es502568z. Epub 2014 Nov 6.

PMID:
25317817
18.

β-agonists selectively modulate proinflammatory gene expression in skeletal muscle cells via non-canonical nuclear crosstalk mechanisms.

Kolmus K, Van Troys M, Van Wesemael K, Ampe C, Haegeman G, Tavernier J, Gerlo S.

PLoS One. 2014 Mar 6;9(6):e90649. doi: 10.1371/journal.pone.0090649. eCollection 2014.

19.

Beta-actin is required for proper mouse neural crest ontogeny.

Tondeleir D, Noelanders R, Bakkali K, Ampe C.

PLoS One. 2014 Jan 7;9(1):e85608. doi: 10.1371/journal.pone.0085608. eCollection 2014.

20.

Biophysical approaches for investigation of the cytoskeleton. A special issue stemming from research presented at the 2012 ECF meeting: a FEBS/EMBO workshop lecture course in Pécs, Hungary.

Ampe C, Machesky LM, Nyitrai M.

Cytoskeleton (Hoboken). 2013 Oct;70(10):539. doi: 10.1002/cm.21145. No abstract available.

PMID:
24166833
21.

β-Actin knock-out mouse embryonic fibroblasts show increased expression of LIM-, CH-, EFh-domain containing proteins with predicted common upstream regulators.

Ampe C, Libbrecht J, Van Troys M.

Cytoskeleton (Hoboken). 2013 Nov;70(11):766-74. doi: 10.1002/cm.21147. Epub 2013 Oct 21.

PMID:
24123846
22.

CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP.

Disanza A, Bisi S, Winterhoff M, Milanesi F, Ushakov DS, Kast D, Marighetti P, Romet-Lemonne G, Müller HM, Nickel W, Linkner J, Waterschoot D, Ampè C, Cortellino S, Palamidessi A, Dominguez R, Carlier MF, Faix J, Scita G.

EMBO J. 2013 Oct 16;32(20):2735-50. doi: 10.1038/emboj.2013.208. Epub 2013 Sep 27.

23.

CellMissy: a tool for management, storage and analysis of cell migration data produced in wound healing-like assays.

Masuzzo P, Hulstaert N, Huyck L, Ampe C, Van Troys M, Martens L.

Bioinformatics. 2013 Oct 15;29(20):2661-3. doi: 10.1093/bioinformatics/btt437. Epub 2013 Aug 5.

24.

Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels.

Tondeleir D, Drogat B, Slowicka K, Bakkali K, Bartunkova S, Goossens S, Haigh JJ, Ampe C.

PLoS One. 2013 Jun 26;8(6):e67855. doi: 10.1371/journal.pone.0067855. Print 2013.

25.

Alphaherpesviral US3 kinase induces cofilin dephosphorylation to reorganize the actin cytoskeleton.

Jacob T, Van den Broeke C, van Troys M, Waterschoot D, Ampe C, Favoreel HW.

J Virol. 2013 Apr;87(7):4121-6. doi: 10.1128/JVI.03107-12. Epub 2013 Jan 30.

26.

p210bcr-abl induces amoeboid motility by recruiting ADF/destrin through RhoA/ROCK1.

Rochelle T, Daubon T, Van Troys M, Harnois T, Waterschoot D, Ampe C, Roy L, Bourmeyster N, Constantin B.

FASEB J. 2013 Jan;27(1):123-34. doi: 10.1096/fj.12-205112. Epub 2012 Oct 9.

PMID:
23047898
27.

The XTT cell proliferation assay applied to cell layers embedded in three-dimensional matrix.

Huyck L, Ampe C, Van Troys M.

Assay Drug Dev Technol. 2012 Aug;10(4):382-92. doi: 10.1089/adt.2011.391. Epub 2012 May 10.

28.

Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity.

Tondeleir D, Lambrechts A, Müller M, Jonckheere V, Doll T, Vandamme D, Bakkali K, Waterschoot D, Lemaistre M, Debeir O, Decaestecker C, Hinz B, Staes A, Timmerman E, Colaert N, Gevaert K, Vandekerckhove J, Ampe C.

Mol Cell Proteomics. 2012 Aug;11(8):255-71. doi: 10.1074/mcp.M111.015099. Epub 2012 Mar 22.

29.

Phosphosite conservation in single domain orthologs versus paralogs: a way to combine differential regulation with redundant core functions.

Huyck L, Van Troys M, Ampe C.

FEBS Lett. 2012 Feb 17;586(4):296-302. doi: 10.1016/j.febslet.2012.01.018. Epub 2012 Jan 18.

30.

Intermolecular interaction studies using small volumes.

Bourry D, Sinnaeve D, Gheysen K, Fritzinger B, Vandenborre G, Van Damme EJ, Wieruszeski JM, Lippens G, Ampe C, Martins JC.

Magn Reson Chem. 2011 Jan;49(1):9-15. doi: 10.1002/mrc.2699. Epub 2010 Nov 29.

PMID:
21162136
31.

A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics.

Meixner A, Boldt K, Van Troys M, Askenazi M, Gloeckner CJ, Bauer M, Marto JA, Ampe C, Kinkl N, Ueffing M.

Mol Cell Proteomics. 2011 Jan;10(1):M110.001172. doi: 10.1074/mcp.M110.001172. Epub 2010 Sep 27.

32.

Identification and expression analysis of splice variants of mouse enabled homologue during development and in adult tissues.

Veniere S, Waterschoot D, Vandekerckhove J, Lambrechts A, Ampe C.

BMC Mol Biol. 2010 Jun 17;11:45. doi: 10.1186/1471-2199-11-45.

33.

Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering.

Leyman S, Sidani M, Ritsma L, Waterschoot D, Eddy R, Dewitte D, Debeir O, Decaestecker C, Vandekerckhove J, van Rheenen J, Ampe C, Condeelis J, Van Troys M.

Mol Biol Cell. 2009 Nov;20(21):4509-23. doi: 10.1091/mbc.E09-02-0121. Epub 2009 Sep 9.

34.

The interaction of proline-rich ligands with profilin probed with an enzyme-linked immunosorbent assay.

Veniere S, Ampe C, Vandekerckhove J, Lambrechts A.

J Biomol Screen. 2009 Apr;14(4):350-9. doi: 10.1177/1087057109332594.

PMID:
19403918
35.

alpha-Skeletal muscle actin nemaline myopathy mutants cause cell death in cultured muscle cells.

Vandamme D, Lambert E, Waterschoot D, Cognard C, Vandekerckhove J, Ampe C, Constantin B, Rommelaere H.

Biochim Biophys Acta. 2009 Jul;1793(7):1259-71. doi: 10.1016/j.bbamcr.2009.04.004. Epub 2009 Apr 21.

36.

Actin isoform expression patterns during mammalian development and in pathology: insights from mouse models.

Tondeleir D, Vandamme D, Vandekerckhove J, Ampe C, Lambrechts A.

Cell Motil Cytoskeleton. 2009 Oct;66(10):798-815. doi: 10.1002/cm.20350. Review.

PMID:
19296487
37.

Phenotypes induced by NM causing alpha-skeletal muscle actin mutants in fibroblasts, Sol 8 myoblasts and myotubes.

Vandamme D, Lambert E, Waterschoot D, Tondeleir D, Vandekerckhove J, Machesky LM, Constantin B, Rommelaere H, Ampe C.

BMC Res Notes. 2009 Mar 10;2:40. doi: 10.1186/1756-0500-2-40.

38.

The mouse thymosin beta15 gene family displays unique complexity and encodes a functional thymosin repeat.

Dhaese S, Vandepoele K, Waterschoot D, Vanloo B, Vandekerckhove J, Ampe C, Van Troys M.

J Mol Biol. 2009 Apr 10;387(4):809-25. doi: 10.1016/j.jmb.2009.02.026. Epub 2009 Feb 20.

PMID:
19233202
39.

alpha-Skeletal muscle actin mutants causing different congenital myopathies induce similar cytoskeletal defects in cell line cultures.

Vandamme D, Rommelaere H, Lambert E, Waterschoot D, Vandekerckhove J, Constantin B, Ampe C.

Cell Motil Cytoskeleton. 2009 Apr;66(4):179-92. doi: 10.1002/cm.20340.

PMID:
19206168
40.

An integrative simulation model linking major biochemical reactions of actin-polymerization to structural properties of actin filaments.

Halavatyi AA, Nazarov PV, Medves S, van Troys M, Ampe C, Yatskou M, Friederich E.

Biophys Chem. 2009 Mar;140(1-3):24-34. doi: 10.1016/j.bpc.2008.11.006. Epub 2008 Nov 27.

PMID:
19101066
41.

Ins and outs of ADF/cofilin activity and regulation.

Van Troys M, Huyck L, Leyman S, Dhaese S, Vandekerkhove J, Ampe C.

Eur J Cell Biol. 2008 Sep;87(8-9):649-67. doi: 10.1016/j.ejcb.2008.04.001. Epub 2008 May 21. Review.

PMID:
18499298
42.

Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants.

Piana S, Laio A, Marinelli F, Van Troys M, Bourry D, Ampe C, Martins JC.

J Mol Biol. 2008 Jan 11;375(2):460-70. Epub 2007 Oct 13.

PMID:
18022635
43.

Functional and profiling studies prove that prostate cancer upregulated neuroblastoma thymosin beta is the true human homologue of rat thymosin beta15.

Dhaese S, Jonckheere V, Goethals M, Waltregny D, Vandekerckhove J, Ampe C, Van Troys M.

FEBS Lett. 2007 Oct 16;581(25):4809-15. Epub 2007 Sep 12.

44.

The LIM domains of WLIM1 define a new class of actin bundling modules.

Thomas C, Moreau F, Dieterle M, Hoffmann C, Gatti S, Hofmann C, Van Troys M, Ampe C, Steinmetz A.

J Biol Chem. 2007 Nov 16;282(46):33599-608. Epub 2007 Sep 7.

45.

On the origin and evolution of vertebrate and viral profilins.

Polet D, Lambrechts A, Vandepoele K, Vandekerckhove J, Ampe C.

FEBS Lett. 2007 Jan 23;581(2):211-7. Epub 2006 Dec 14.

46.

Tobacco WLIM1 is a novel F-actin binding protein involved in actin cytoskeleton remodeling.

Thomas C, Hoffmann C, Dieterle M, Van Troys M, Ampe C, Steinmetz A.

Plant Cell. 2006 Sep;18(9):2194-206. Epub 2006 Aug 11.

47.

Cell_motility: a cross-platform, open source application for the study of cell motion paths.

Martens L, Monsieur G, Ampe C, Gevaert K, Vandekerckhove J.

BMC Bioinformatics. 2006 Jun 8;7:289.

48.

Identification of the PXW sequence as a structural gatekeeper of the headpiece C-terminal subdomain fold.

Vermeulen W, Van Troys M, Bourry D, Dewitte D, Rossenu S, Goethals M, Borremans FA, Vandekerckhove J, Martins JC, Ampe C.

J Mol Biol. 2006 Jun 23;359(5):1277-92. Epub 2006 May 6.

PMID:
16697408
49.

Profilin-I-ligand interactions influence various aspects of neuronal differentiation.

Lambrechts A, Jonckheere V, Peleman C, Polet D, De Vos W, Vandekerckhove J, Ampe C.

J Cell Sci. 2006 Apr 15;119(Pt 8):1570-8. Epub 2006 Mar 28.

50.

Caenorhabditis elegans expresses three functional profilins in a tissue-specific manner.

Polet D, Lambrechts A, Ono K, Mah A, Peelman F, Vandekerckhove J, Baillie DL, Ampe C, Ono S.

Cell Motil Cytoskeleton. 2006 Jan;63(1):14-28.

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