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Items: 13

1.

Phase I Study of AMG 337, a Highly Selective Small-molecule MET Inhibitor, in Patients with Advanced Solid Tumors.

Hong DS, LoRusso P, Hamid O, Janku F, Kittaneh M, Catenacci DVT, Chan E, Bekaii-Saab T, Gadgeel SM, Loberg RD, Amore BM, Hwang YC, Tang R, Ngarmchamnanrith G, Kwak EL.

Clin Cancer Res. 2019 Apr 15;25(8):2403-2413. doi: 10.1158/1078-0432.CCR-18-1341. Epub 2018 Nov 13.

PMID:
30425090
2.

First-in-Human Study of AMG 820, a Monoclonal Anti-Colony-Stimulating Factor 1 Receptor Antibody, in Patients with Advanced Solid Tumors.

Papadopoulos KP, Gluck L, Martin LP, Olszanski AJ, Tolcher AW, Ngarmchamnanrith G, Rasmussen E, Amore BM, Nagorsen D, Hill JS, Stephenson J Jr.

Clin Cancer Res. 2017 Oct 1;23(19):5703-5710. doi: 10.1158/1078-0432.CCR-16-3261. Epub 2017 Jun 27.

3.

A Phase 1 study evaluating AMG 337 in Asian patients with advanced solid tumors.

Yasui H, Go N, Yang H, Amore BM, Jung AS, Doi T.

Jpn J Clin Oncol. 2017 Aug 1;47(8):772-776. doi: 10.1093/jjco/hyx067.

PMID:
28582510
4.

Intestinal and hepatic first-pass extraction of the 11β-HSD1 inhibitor AMG 221 in rats with chronic vascular catheters.

Gao Q, Kimura RE, Zhang X, Nam J, Amore BM, Hickman D, Greg Slatter J, Emery MG.

Xenobiotica. 2014 Mar;44(3):264-9. doi: 10.3109/00498254.2013.769074. Epub 2013 Mar 21.

PMID:
23517558
5.

Predicting the drug interaction potential of AMG 853, a dual antagonist of the D-prostanoid and chemoattractant receptor-homologous molecule expressed on T helper 2 cells receptors.

Foti RS, Pearson JT, Wong SL, Zalikowski JA, Boudreaux MD, Prokop SP, Davis JA, Banfield C, Emery MG, Rock DA, Wahlstrom JL, Wienkers LC, Amore BM.

Drug Metab Dispos. 2012 Dec;40(12):2239-49. doi: 10.1124/dmd.112.047928. Epub 2012 Aug 28.

PMID:
22930276
6.

Application of in vivo animal models to characterize the pharmacokinetic and pharmacodynamic properties of drug candidates in discovery settings.

Amore BM, Gibbs JP, Emery MG.

Comb Chem High Throughput Screen. 2010 Feb;13(2):207-18. Review.

PMID:
20053166
7.

Influence of molecular flexibility and polar surface area metrics on oral bioavailability in the rat.

Lu JJ, Crimin K, Goodwin JT, Crivori P, Orrenius C, Xing L, Tandler PJ, Vidmar TJ, Amore BM, Wilson AG, Stouten PF, Burton PS.

J Med Chem. 2004 Nov 18;47(24):6104-7.

PMID:
15537364
8.

Characterization of bropirimine O-glucuronidation in human liver microsomes.

Wynalda MA, Wynalda KM, Amore BM, Fagerness PE, Wienkers LC.

Xenobiotica. 2003 Oct;33(10):999-1011.

PMID:
14555337
9.

Predicting drug absorption: how nature made it a difficult problem.

Burton PS, Goodwin JT, Vidmar TJ, Amore BM.

J Pharmacol Exp Ther. 2002 Dec;303(3):889-95. Review.

PMID:
12438506
10.

Characterization of carbamazepine metabolism in a mouse model of carbamazepine teratogenicity.

Amore BM, Kalhorn TF, Skiles GL, Hunter AP, Bennett GD, Finnell RH, Nelson SD, Slattery JT.

Drug Metab Dispos. 1997 Aug;25(8):953-62.

PMID:
9280403
11.

Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse.

Bennett GD, Amore BM, Finnell RH, Wlodarczyk B, Kalhorn TF, Skiles GL, Nelson SD, Slattery JT.

J Pharmacol Exp Ther. 1996 Dec;279(3):1237-42.

PMID:
8968346
12.

Protein-reactive metabolites of carbamazepine in mouse liver microsomes.

Lillibridge JH, Amore BM, Slattery JT, Kalhorn TF, Nelson SD, Finnell RH, Bennett GD.

Drug Metab Dispos. 1996 May;24(5):509-14.

PMID:
8723729
13.

Effect of treatment with phenobarbital and stiripentol on carbamazepine-induced teratogenicity and reactive metabolite formation.

Finnell RH, Bennett GD, Slattery JT, Amore BM, Bajpai M, Levy RH.

Teratology. 1995 Dec;52(6):324-32.

PMID:
8711619

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