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Items: 1 to 50 of 79

1.

Neurobehavioral investigation and acetylcholinesterase inhibitory activity study for some new coumarin derivatives.

Mahmoud WR, Nissan YM, Elsawah MM, Refaey RH, Ragab MF, Amin KM.

Eur J Med Chem. 2019 Aug 28;182:111651. doi: 10.1016/j.ejmech.2019.111651. [Epub ahead of print]

PMID:
31479975
2.

Synthesis and in vitro anticancer evaluation of some fused indazoles, quinazolines and quinolines as potential EGFR inhibitors.

Abdelsalam EA, Zaghary WA, Amin KM, Abou Taleb NA, Mekawey AAI, Eldehna WM, Abdel-Aziz HA, Hammad SF.

Bioorg Chem. 2019 Aug;89:102985. doi: 10.1016/j.bioorg.2019.102985. Epub 2019 May 15.

PMID:
31121559
3.

Visnagin and benzofuran scaffold-based molecules as selective cyclooxygenase-2 inhibitors with anti-inflammatory and analgesic properties: design, synthesis and molecular docking.

Khalil HS, Sedky NK, Amin KM, Abd Elhafez OM, Arafa RK.

Future Med Chem. 2019 Apr;11(7):659-676. doi: 10.4155/fmc-2018-0398. Epub 2019 Apr 8.

PMID:
30958028
4.

Synthesis, molecular modeling studies, and anticonvulsant evaluation of novel 1-((2-hydroxyethyl)(aryl)amino)-N-substituted cycloalkanecarboxamides and their acetate esters.

Aboul-Enein MN, El-Azzouny AA, Amin KM, Aboutabl ME, Abo-Elmagd MI.

Arch Pharm (Weinheim). 2018 Dec;351(12):e1800269. doi: 10.1002/ardp.201800269. Epub 2018 Nov 21.

PMID:
30461033
5.

Molecular docking simulation, synthesis and 3D pharmacophore studies of novel 2-substituted-5-nitro-benzimidazole derivatives as anticancer agents targeting VEGFR-2 and c-Met.

Ibrahim HA, Awadallah FM, Refaat HM, Amin KM.

Bioorg Chem. 2018 Apr;77:457-470. doi: 10.1016/j.bioorg.2018.01.014. Epub 2018 Jan 31. No abstract available.

PMID:
29453077
6.

Design, synthesis and molecular modeling study for some new 2-substituted benzimidazoles as dual inhibitors for VEGFR-2 and c-Met.

Ibrahim HA, Awadallah FM, Refaat HM, Amin KM.

Future Med Chem. 2018 Mar 1;10(5):493-509. doi: 10.4155/fmc-2017-0174. Epub 2018 Feb 12.

PMID:
29431476
7.

Synthesis and molecular docking study of new benzofuran and furo[3,2-g]chromone-based cytotoxic agents against breast cancer and p38α MAP kinase inhibitors.

Amin KM, Syam YM, Anwar MM, Ali HI, Abdel-Ghani TM, Serry AM.

Bioorg Chem. 2018 Feb;76:487-500. doi: 10.1016/j.bioorg.2017.12.029. Epub 2018 Jan 2.

PMID:
29310080
8.

A novel white blood cells segmentation algorithm based on adaptive neutrosophic similarity score.

Shahin AI, Guo Y, Amin KM, Sharawi AA.

Health Inf Sci Syst. 2017 Dec 18;6(1):1. doi: 10.1007/s13755-017-0038-5. eCollection 2018 Dec.

PMID:
29279774
9.

Enantioseparation of Substituted 1, 3-Diazaspiro [4.5]Decan-4-Ones: HPLC Comparative Study on Different Polysaccharide Type Chiral Stationary Phases.

Aboul-Enein HY, Aboul-Enein MN, El-Azzouny AA, Saleh OA, Hassan RM, Amin KM.

J Chromatogr Sci. 2018 Feb 1;56(2):160-165. doi: 10.1093/chromsci/bmx098.

PMID:
29190324
10.

White blood cells identification system based on convolutional deep neural learning networks.

Shahin AI, Guo Y, Amin KM, Sharawi AA.

Comput Methods Programs Biomed. 2019 Jan;168:69-80. doi: 10.1016/j.cmpb.2017.11.015. Epub 2017 Nov 16.

PMID:
29173802
11.

Synthesis, antitumor activity evaluation, and DNA-binding study of coumarin-based agents.

Amin KM, Taha AM, George RF, Mohamed NM, Elsenduny FF.

Arch Pharm (Weinheim). 2018 Jan;351(1). doi: 10.1002/ardp.201700199. Epub 2017 Nov 17.

PMID:
29148081
12.

Synthesis and molecular docking studies of new furochromone derivatives as p38α MAPK inhibitors targeting human breast cancer MCF-7 cells.

Amin KM, Syam YM, Anwar MM, Ali HI, Abdel-Ghani TM, Serry AM.

Bioorg Med Chem. 2017 Apr 15;25(8):2423-2436. doi: 10.1016/j.bmc.2017.02.065. Epub 2017 Mar 3.

PMID:
28291685
13.

Role of courtyard counselling meeting in improving household food safety knowledge and practices in Munshiganj district of Bangladesh.

Riaz BK, Alim MA, Islam AS, Amin KB, Sarker MA, Hasan K, Ashad-Uz-Zaman MN, Selim S, Quaiyum S, Haque E, Monir Hossain S, Ryder J, Khanam R.

Nagoya J Med Sci. 2016 Dec;78(4):387-398. doi: 10.18999/nagjms.78.4.387.

14.

Identification of new potent phthalazine derivatives with VEGFR-2 and EGFR kinase inhibitory activity.

Amin KM, Barsoum FF, Awadallah FM, Mohamed NE.

Eur J Med Chem. 2016 Nov 10;123:191-201. doi: 10.1016/j.ejmech.2016.07.049. Epub 2016 Jul 22.

PMID:
27484508
15.

Synthesis and Anticonvulsant Activity of Substituted-1,3-diazaspiro[4.5]decan-4-ones.

Aboul-Enein MN, El-Azzouny AA, Saleh OA, Amin KM, Maklad YA, Hassan RM.

Arch Pharm (Weinheim). 2015 Aug;348(8):575-88. doi: 10.1002/ardp.201500092. Epub 2015 May 29.

PMID:
26032619
16.

Computer-aided identification of novel anticancer compounds with a possible dual HER1/HER2 inhibition mechanism.

Elseginy SA, Lazaro G, Nawwar GA, Amin KM, Hiscox S, Brancale A.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):758-62. doi: 10.1016/j.bmcl.2014.12.095. Epub 2015 Jan 6.

PMID:
25619636
17.

Synthesis and anticancer activity of some 8-substituted-7-methoxy-2H-chromen-2-one derivatives toward hepatocellular carcinoma HepG2 cells.

Amin KM, Abou-Seri SM, Awadallah FM, Eissa AA, Hassan GS, Abdulla MM.

Eur J Med Chem. 2015 Jan 27;90:221-31. doi: 10.1016/j.ejmech.2014.11.027. Epub 2014 Nov 15.

PMID:
25461322
18.

New series of 6-substituted coumarin derivatives as effective factor Xa inhibitors: synthesis, in vivo antithrombotic evaluation and molecular docking.

Amin KM, Abdel Gawad NM, Abdel Rahman DE, El Ashry MK.

Bioorg Chem. 2014 Feb;52:31-43. doi: 10.1016/j.bioorg.2013.11.002. Epub 2013 Nov 20.

PMID:
24316885
19.

Synthesis, cytotoxic evaluation and molecular docking study of novel quinazoline derivatives as PARP-1 inhibitors.

Amin KM, Anwar MM, Kamel MM, Kassem EM, Syam YM, Elseginy SA.

Acta Pol Pharm. 2013 Sep-Oct;70(5):833-49.

20.

A novel class of substituted spiro [quinazoline-2,1'-cyclohexane] derivatives as effective PPAR-1 inhibitors: molecular modeling, synthesis, cytotoxic and enzyme assay evaluation.

Amin KM, Anwar MM, Syam YM, Khedr MA, Kamel MM, Kassem EM.

Acta Pol Pharm. 2013 Jul-Aug;70(4):687-708. Erratum in: Acta Pol Pharm. 2013 Sep-Oct;70(5):939. Khedr, Mohammed [corrected to Khedr, Mohammed A].

21.

Small molecule inhibitors of West Nile virus.

Elseginy SA, Massarotti A, Nawwar GA, Amin KM, Brancale A.

Antivir Chem Chemother. 2014 Apr 11;23(5):179-87. doi: 10.3851/IMP2581. Review.

PMID:
23636899
22.

Synthesis and biological evaluation of novel coumarin-pyrazoline hybrids endowed with phenylsulfonyl moiety as antitumor agents.

Amin KM, Eissa AA, Abou-Seri SM, Awadallah FM, Hassan GS.

Eur J Med Chem. 2013 Feb;60:187-98. doi: 10.1016/j.ejmech.2012.12.004. Epub 2012 Dec 12.

PMID:
23291120
23.

Monoamine oxidase A and B inhibiting effect and molecular modeling of some synthesized coumarin derivatives.

Abdelhafez OM, Amin KM, Ali HI, Abdalla MM, Batran RZ.

Neurochem Int. 2013 Jan;62(2):198-209. doi: 10.1016/j.neuint.2012.11.005. Epub 2012 Nov 24.

PMID:
23182697
24.

Synthesis of new 7-oxycoumarin derivatives as potent and selective monoamine oxidase A inhibitors.

Abdelhafez OM, Amin KM, Ali HI, Abdalla MM, Batran RZ.

J Med Chem. 2012 Dec 13;55(23):10424-36. doi: 10.1021/jm301014y. Epub 2012 Nov 30.

PMID:
23153282
25.

Synthesis, spectroscopic characterization and biological activities of N₄O₂ Schiff base ligand and its metal complexes of Co(II), Ni(II), Cu(II) and Zn(II).

Al-Resayes SI, Shakir M, Abbasi A, Amin KM, Lateef A.

Spectrochim Acta A Mol Biomol Spectrosc. 2012 Jul;93:86-94. doi: 10.1016/j.saa.2012.02.099. Epub 2012 Mar 3.

PMID:
22465773
26.

Design and synthesis of novel stiripentol analogues as potential anticonvulsants.

Aboul-Enein MN, El-Azzouny AA, Attia MI, Maklad YA, Amin KM, Abdel-Rehim M, El-Behairy MF.

Eur J Med Chem. 2012 Jan;47(1):360-9. doi: 10.1016/j.ejmech.2011.11.004. Epub 2011 Nov 11.

PMID:
22118828
27.

Synthesis of new 9-glycosyl-4,9-dihydropyrano [3,4-b]indole-1(3H)-ones as antibacterial agents.

Kassab SE, Hegazy GH, Eid NM, Amin KM, El-Gendy AA.

Nucleosides Nucleotides Nucleic Acids. 2011 Nov;30(11):991-8. doi: 10.1080/15257770.2011.630334.

PMID:
22060560
28.

Design, synthesis and vasorelaxant evaluation of novel coumarin-pyrimidine hybrids.

Amin KM, Awadalla FM, Eissa AA, Abou-Seri SM, Hassan GS.

Bioorg Med Chem. 2011 Oct 15;19(20):6087-97. doi: 10.1016/j.bmc.2011.08.037. Epub 2011 Aug 22.

PMID:
21908192
29.

Dopamine release and molecular modeling study of some coumarin derivatives.

Abdelhafez OM, Amin KM, Ali HI, Maher TJ, Batran RZ.

Neurochem Int. 2011 Nov;59(6):906-12. doi: 10.1016/j.neuint.2011.08.004. Epub 2011 Aug 18.

PMID:
21871512
30.

Synthesis, anticoagulant and PIVKA-II induced by new 4-hydroxycoumarin derivatives.

Abdelhafez OM, Amin KM, Batran RZ, Maher TJ, Nada SA, Sethumadhavan S.

Bioorg Med Chem. 2010 May 15;18(10):3371-8. doi: 10.1016/j.bmc.2010.04.009. Epub 2010 Apr 8.

PMID:
20435480
31.

Synthesis of 1H-indole-2,3-dione-3-thiosemicarbazone ribonucleosides as antibacterial agents.

Kassab SE, Hegazy GH, Eid NM, Amin KM, El-Gendy AA.

Nucleosides Nucleotides Nucleic Acids. 2010 Jan;29(1):72-80. doi: 10.1080/15257770903459267.

PMID:
20391194
32.

New quinoxaline 1, 4-di-N-oxides: anticancer and hypoxia-selective therapeutic agents.

Ismail MM, Amin KM, Noaman E, Soliman DH, Ammar YA.

Eur J Med Chem. 2010 Jul;45(7):2733-8. doi: 10.1016/j.ejmech.2010.02.052. Epub 2010 Mar 1.

PMID:
20236735
33.

Synthesis, biological evaluation and molecular docking of novel series of spiro [(2H,3H) quinazoline-2,1'- cyclohexan]-4(1H)- one derivatives as anti-inflammatory and analgesic agents.

Amin KM, Kamel MM, Anwar MM, Khedr M, Syam YM.

Eur J Med Chem. 2010 Jun;45(6):2117-31. doi: 10.1016/j.ejmech.2009.12.078. Epub 2010 Jan 21.

PMID:
20137837
34.

Synthesis and anticancer activity of novel tetralin-6-ylpyridine and tetralin-6-ylpyrimidine derivatives.

Amin KM, El-Zahar MI, Anwar MM, Kamel MM, Mohamed MH.

Acta Pol Pharm. 2009 May-Jun;66(3):279-91.

35.

Synthesis, analgesic and anti-inflammatory activities evaluation of some bi-, tri- and tetracyclic condensed pyrimidines.

Amin KM, Hanna MM, Abo-Youssef HE, George RF.

Eur J Med Chem. 2009 Nov;44(11):4572-84. doi: 10.1016/j.ejmech.2009.06.028. Epub 2009 Jul 1.

PMID:
19628310
36.

Synthesis and antitumor activity of some new xanthotoxin derivatives.

Abdel Hafez OM, Amin KM, Abdel-Latif NA, Mohamed TK, Ahmed EY, Maher T.

Eur J Med Chem. 2009 Jul;44(7):2967-74. doi: 10.1016/j.ejmech.2009.01.006. Epub 2009 Jan 19.

PMID:
19217697
37.

Synthesis and preliminary evaluation of some substituted coumarins as anticonvulsant agents.

Amin KM, Rahman DE, Al-Eryani YA.

Bioorg Med Chem. 2008 May 15;16(10):5377-88. doi: 10.1016/j.bmc.2008.04.021. Epub 2008 Apr 15.

PMID:
18467106
38.

Human myocardial cell lines generated with SV40 temperature-sensitive mutant tsA58.

Goldman BI, Amin KM, Kubo H, Singhal A, Wurzel J.

In Vitro Cell Dev Biol Anim. 2006 Nov-Dec;42(10):324-31.

PMID:
17316067
39.

New quinoxaline 1,4-di-N-oxides. Part 1: Hypoxia-selective cytotoxins and anticancer agents derived from quinoxaline 1,4-di-N-oxides.

Amin KM, Ismail MM, Noaman E, Soliman DH, Ammar YA.

Bioorg Med Chem. 2006 Oct 15;14(20):6917-23. Epub 2006 Jul 14.

PMID:
16843668
40.

New trends in synthesis of pyrazole nucleosides as new antimetabolites.

Elgemeie GH, Zaghary WA, Amin KM, Nasr TM.

Nucleosides Nucleotides Nucleic Acids. 2005;24(8):1227-47. Review.

PMID:
16270665
41.

Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy.

Sterman DH, Recio A, Vachani A, Sun J, Cheung L, DeLong P, Amin KM, Litzky LA, Wilson JM, Kaiser LR, Albelda SM.

Clin Cancer Res. 2005 Oct 15;11(20):7444-53.

42.

Prevalence of Brucella antibodies in sera of cows in Bangladesh.

Amin KM, Rahman MB, Rahman MS, Han JC, Park JH, Chae JS.

J Vet Sci. 2005 Sep;6(3):223-6.

PMID:
16131825
43.

An experimental study of sexual function improving effect of Myristica fragrans Houtt. (nutmeg).

Tajuddin, Ahmad S, Latif A, Qasmi IA, Amin KM.

BMC Complement Altern Med. 2005 Jul 20;5:16.

44.

Fetal liver as a source of autologous progenitor cells for perinatal tissue engineering.

Krupnick AS, Balsara KR, Kreisel D, Riha M, Gelman AE, Estives MS, Amin KM, Rosengard BR, Flake AW.

Tissue Eng. 2004 May-Jun;10(5-6):723-35.

PMID:
15265289
45.

Differentially expressed apoptotic genes in early stage lung adenocarcinoma predicted by expression profiling.

Singhal S, Amin KM, Kruklitis R, Marshall MB, Kucharczuk JC, DeLong P, Litzky LA, Kaiser LR, Albelda SM.

Cancer Biol Ther. 2003 Sep-Oct;2(5):566-71.

PMID:
14614329
46.

Ad5 and Ad3 chimeric fiber travels into the cell without the CAR.

Amin KM.

Cancer Biol Ther. 2003 Sep-Oct;2(5):516-7. No abstract available.

PMID:
14614317
47.

Gene expression profiling of malignant mesothelioma.

Singhal S, Wiewrodt R, Malden LD, Amin KM, Matzie K, Friedberg J, Kucharczuk JC, Litzky LA, Johnson SW, Kaiser LR, Albelda SM.

Clin Cancer Res. 2003 Aug 1;9(8):3080-97.

48.

Alterations in cell cycle genes in early stage lung adenocarcinoma identified by expression profiling.

Singhal S, Amin KM, Kruklitis R, DeLong P, Friscia ME, Litzky LA, Putt ME, Kaiser LR, Albelda SM.

Cancer Biol Ther. 2003 May-Jun;2(3):291-8.

PMID:
12878869
49.
50.

Replication-selective herpes simplex virus type 1 mutant therapy of cervical cancer is enhanced by low-dose radiation.

Blank SV, Rubin SC, Coukos G, Amin KM, Albelda SM, Molnar-Kimber KL.

Hum Gene Ther. 2002 Mar 20;13(5):627-39.

PMID:
11916486

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