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Items: 1 to 50 of 197

1.

Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses.

Durand M, Walter T, Pirnay T, Naessens T, Gueguen P, Goudot C, Lameiras S, Chang Q, Talaei N, Ornatsky O, Vassilevskaia T, Baulande S, Amigorena S, Segura E.

J Exp Med. 2019 Jul 1;216(7):1561-1581. doi: 10.1084/jem.20181994. Epub 2019 May 9.

PMID:
31072818
2.

Translate less, prime better, to improve anti-tumor responses.

Burbage M, Gros M, Amigorena S.

Nat Immunol. 2019 May;20(5):518-520. doi: 10.1038/s41590-019-0371-8. No abstract available.

PMID:
30936492
3.

The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.

Gentili M, Lahaye X, Nadalin F, Nader GPF, Lombardi EP, Herve S, De Silva NS, Rookhuizen DC, Zueva E, Goudot C, Maurin M, Bochnakian A, Amigorena S, Piel M, Fachinetti D, Londoño-Vallejo A, Manel N.

Cell Rep. 2019 Mar 26;26(13):3798. doi: 10.1016/j.celrep.2019.03.049. No abstract available.

4.

The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.

Gentili M, Lahaye X, Nadalin F, Nader GPF, Puig Lombardi E, Herve S, De Silva NS, Rookhuizen DC, Zueva E, Goudot C, Maurin M, Bochnakian A, Amigorena S, Piel M, Fachinetti D, Londoño-Vallejo A, Manel N.

Cell Rep. 2019 Feb 26;26(9):2377-2393.e13. doi: 10.1016/j.celrep.2019.01.105. Erratum in: Cell Rep. 2019 Mar 26;26(13):3798.

5.

Cold Tumors: A Therapeutic Challenge for Immunotherapy.

Bonaventura P, Shekarian T, Alcazer V, Valladeau-Guilemond J, Valsesia-Wittmann S, Amigorena S, Caux C, Depil S.

Front Immunol. 2019 Feb 8;10:168. doi: 10.3389/fimmu.2019.00168. eCollection 2019. Review.

6.

Regulation of Antigen Export to the Cytosol During Cross-Presentation.

Gros M, Amigorena S.

Front Immunol. 2019 Jan 28;10:41. doi: 10.3389/fimmu.2019.00041. eCollection 2019. Review.

7.

The Histone Methyltransferase SETDB1 Controls T Helper Cell Lineage Integrity by Repressing Endogenous Retroviruses.

Adoue V, Binet B, Malbec A, Fourquet J, Romagnoli P, van Meerwijk JPM, Amigorena S, Joffre OP.

Immunity. 2019 Mar 19;50(3):629-644.e8. doi: 10.1016/j.immuni.2019.01.003. Epub 2019 Feb 5.

PMID:
30737147
8.

Adjustment of dendritic cells to the breast-cancer microenvironment is subset specific.

Michea P, Noël F, Zakine E, Czerwinska U, Sirven P, Abouzid O, Goudot C, Scholer-Dahirel A, Vincent-Salomon A, Reyal F, Amigorena S, Guillot-Delost M, Segura E, Soumelis V.

Nat Immunol. 2018 Aug;19(8):885-897. doi: 10.1038/s41590-018-0145-8. Epub 2018 Jul 16.

PMID:
30013147
9.

Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway.

Tang-Huau TL, Gueguen P, Goudot C, Durand M, Bohec M, Baulande S, Pasquier B, Amigorena S, Segura E.

Nat Commun. 2018 Jul 2;9(1):2570. doi: 10.1038/s41467-018-04985-0.

10.

Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells.

Oberkampf M, Guillerey C, Mouriès J, Rosenbaum P, Fayolle C, Bobard A, Savina A, Ogier-Denis E, Enninga J, Amigorena S, Leclerc C, Dadaglio G.

Nat Commun. 2018 Jun 8;9(1):2241. doi: 10.1038/s41467-018-04686-8.

11.

Correction: Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity.

Alloatti A, Rookhuizen DC, Joannas L, Carpier JM, Iborra S, Magalhaes JG, Yatim N, Kozik P, Sancho D, Albert ML, Amigorena S.

J Exp Med. 2018 Mar 5;215(3):1001. doi: 10.1084/jem.2017022902092018c. Epub 2018 Feb 15. No abstract available.

12.

Dendritic Cells on the Way to Glory.

Amigorena S.

J Immunol. 2018 Feb 1;200(3):885-886. doi: 10.4049/jimmunol.1701693. No abstract available.

13.

The epigenetic control of stemness in CD8+ T cell fate commitment.

Pace L, Goudot C, Zueva E, Gueguen P, Burgdorf N, Waterfall JJ, Quivy JP, Almouzni G, Amigorena S.

Science. 2018 Jan 12;359(6372):177-186. doi: 10.1126/science.aah6499.

PMID:
29326266
14.

Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery.

Clemente T, Vieira NJ, Cerliani JP, Adrain C, Luthi A, Dominguez MR, Yon M, Barrence FC, Riul TB, Cummings RD, Zorn TM, Amigorena S, Dias-Baruffi M, Rodrigues MM, Martin SJ, Rabinovich GA, Amarante-Mendes GP.

Cell Death Dis. 2017 Dec 7;8(12):e3176. doi: 10.1038/cddis.2017.506.

15.

Whole-cell biopanning with a synthetic phage display library of nanobodies enabled the recovery of follicle-stimulating hormone receptor inhibitors.

Crepin R, Veggiani G, Djender S, Beugnet A, Planeix F, Pichon C, Moutel S, Amigorena S, Perez F, Ghinea N, de Marco A.

Biochem Biophys Res Commun. 2017 Dec 2;493(4):1567-1572. doi: 10.1016/j.bbrc.2017.10.036. Epub 2017 Oct 7.

PMID:
29017919
16.

A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis.

Cepika AM, Banchereau R, Segura E, Ohouo M, Cantarel B, Goller K, Cantrell V, Ruchaud E, Gatewood E, Nguyen P, Gu J, Anguiano E, Zurawski S, Baisch JM, Punaro M, Baldwin N, Obermoser G, Palucka K, Banchereau J, Amigorena S, Pascual V.

J Exp Med. 2017 Nov 6;214(11):3449-3466. doi: 10.1084/jem.20170412. Epub 2017 Sep 21.

17.

Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages.

Goudot C, Coillard A, Villani AC, Gueguen P, Cros A, Sarkizova S, Tang-Huau TL, Bohec M, Baulande S, Hacohen N, Amigorena S, Segura E.

Immunity. 2017 Sep 19;47(3):582-596.e6. doi: 10.1016/j.immuni.2017.08.016.

18.

Blood monocytes sample MelanA/MART1 antigen for long-lasting cross-presentation to CD8+ T cells after differentiation into dendritic cells.

Faure F, Jouve M, Lebhar-Peguillet I, Sadaka C, Sepulveda F, Lantz O, Berre S, Gaudin R, Sánchez-Ramón S, Amigorena S.

Int J Cancer. 2018 Jan 1;142(1):133-144. doi: 10.1002/ijc.31037. Epub 2017 Sep 26.

19.

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export.

Grotzke JE, Kozik P, Morel JD, Impens F, Pietrosemoli N, Cresswell P, Amigorena S, Demangel C.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5910-E5919. doi: 10.1073/pnas.1705242114. Epub 2017 Jul 5.

20.

Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity.

Alloatti A, Rookhuizen DC, Joannas L, Carpier JM, Iborra S, Magalhaes JG, Yatim N, Kozik P, Sancho D, Albert ML, Amigorena S.

J Exp Med. 2017 Aug 7;214(8):2231-2241. doi: 10.1084/jem.20170229. Epub 2017 Jun 29. Erratum in: J Exp Med. 2018 Feb 15;:.

21.

Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.

Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg MC, Picard C, Neven B, Fischer A, Amigorena S, Rieux-Laucat F, Manel N.

J Exp Med. 2017 Jun 5;214(6):1769-1785. doi: 10.1084/jem.20161674. Epub 2017 May 8.

22.

Analysis of Phagosomal Antigen Degradation by Flow Organellocytometry.

Hoffmann E, Pauwels AM, Alloatti A, Kotsias F, Amigorena S.

Bio Protoc. 2016 Nov 20;6(22). pii: e2014.

23.

Evaluation of Cross-presentation in Bone Marrow-derived Dendritic Cells in vitro and Splenic Dendritic Cells ex vivo Using Antigen-coated Beads.

Alloatti A, Kotsias F, Hoffmann E, Amigorena S.

Bio Protoc. 2016 Nov 20;6(22). pii: e2015. doi: 10.21769/BioProtoc.2015.

24.

Antigen-Primed CD8+ T Cells Call DCs for Back Up.

Burbage M, Amigorena S.

Immunity. 2017 Feb 21;46(2):163-164. doi: 10.1016/j.immuni.2017.02.002.

25.

Nanobodies against surface biomarkers enable the analysis of tumor genetic heterogeneity in uveal melanoma patient-derived xenografts.

Crépin R, Gentien D, Duché A, Rapinat A, Reyes C, Némati F, Massonnet G, Decaudin D, Djender S, Moutel S, Desrumeaux K, Cassoux N, Piperno-Neumann S, Amigorena S, Perez F, Roman-Roman S, de Marco A.

Pigment Cell Melanoma Res. 2017 May;30(3):317-327. doi: 10.1111/pcmr.12577. Epub 2017 Apr 19.

PMID:
28140525
26.

Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation.

den Brok MH, Büll C, Wassink M, de Graaf AM, Wagenaars JA, Minderman M, Thakur M, Amigorena S, Rijke EO, Schrier CC, Adema GJ.

Nat Commun. 2016 Nov 7;7:13324. doi: 10.1038/ncomms13324.

27.

Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen.

Sedlik C, Heitzmann A, Viel S, Ait Sarkouh R, Batisse C, Schmidt F, De La Rochere P, Amzallag N, Osinaga E, Oppezzo P, Pritsch O, Sastre-Garau X, Hubert P, Amigorena S, Piaggio E.

Oncoimmunology. 2016 Apr 22;5(7):e1171434. doi: 10.1080/2162402X.2016.1171434. eCollection 2016 Jul.

28.

Dendritic cell maturation and cross-presentation: timing matters!

Alloatti A, Kotsias F, Magalhaes JG, Amigorena S.

Immunol Rev. 2016 Jul;272(1):97-108. doi: 10.1111/imr.12432. Review.

PMID:
27319345
29.

Antigen presentation: from cell biology to physiology.

Amigorena S.

Immunol Rev. 2016 Jul;272(1):5-7. doi: 10.1111/imr.12436. No abstract available.

PMID:
27319337
30.

Heparan sulfates targeting increases MHC class I- and MHC class II-restricted antigen presentation and CD8(+) T-cell response.

Knittel D, Gadzinski A, Hua S, Denizeau J, Savatier A, de la Rochère P, Boulain JC, Amigorena S, Piaggio E, Sedlik C, Léonetti M.

Vaccine. 2016 Jun 8;34(27):3093-3101. doi: 10.1016/j.vaccine.2016.04.073. Epub 2016 May 4.

PMID:
27154391
31.

Measurement of Export to the Cytosol in Dendritic Cells Using a Cytofluorimetry-Based Assay.

Vivar OI, Magalhaes JG, Amigorena S.

Methods Mol Biol. 2016;1423:183-8. doi: 10.1007/978-1-4939-3606-9_13.

PMID:
27142017
32.

Dendritic cell-derived exosomes for cancer therapy.

Pitt JM, André F, Amigorena S, Soria JC, Eggermont A, Kroemer G, Zitvogel L.

J Clin Invest. 2016 Apr 1;126(4):1224-32. doi: 10.1172/JCI81137. Epub 2016 Apr 1. Review.

33.

The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity.

Laubreton D, Bay S, Sedlik C, Artaud C, Ganneau C, Dériaud E, Viel S, Puaux AL, Amigorena S, Gérard C, Lo-Man R, Leclerc C.

Cancer Immunol Immunother. 2016 Mar;65(3):315-25. doi: 10.1007/s00262-016-1802-0. Epub 2016 Feb 4.

34.

IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo.

Vivar OI, Masi G, Carpier JM, Magalhaes JG, Galgano D, Pazour GJ, Amigorena S, Hivroz C, Baldari CT.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):386-91. doi: 10.1073/pnas.1513601113. Epub 2015 Dec 29.

35.

Toll-like Receptor 4 Engagement on Dendritic Cells Restrains Phago-Lysosome Fusion and Promotes Cross-Presentation of Antigens.

Alloatti A, Kotsias F, Pauwels AM, Carpier JM, Jouve M, Timmerman E, Pace L, Vargas P, Maurin M, Gehrmann U, Joannas L, Vivar OI, Lennon-Duménil AM, Savina A, Gevaert K, Beyaert R, Hoffmann E, Amigorena S.

Immunity. 2015 Dec 15;43(6):1087-100. doi: 10.1016/j.immuni.2015.11.006.

36.

Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing.

Decque A, Joffre O, Magalhaes JG, Cossec JC, Blecher-Gonen R, Lapaquette P, Silvin A, Manel N, Joubert PE, Seeler JS, Albert ML, Amit I, Amigorena S, Dejean A.

Nat Immunol. 2016 Feb;17(2):140-9. doi: 10.1038/ni.3342. Epub 2015 Dec 14.

PMID:
26657003
37.

H-Rubies, a new family of red emitting fluorescent pH sensors for living cells.

Despras G, Zamaleeva AI, Dardevet L, Tisseyre C, Magalhaes JG, Garner C, De Waard M, Amigorena S, Feltz A, Mallet JM, Collot M.

Chem Sci. 2015 Oct 1;6(10):5928-5937. doi: 10.1039/c5sc01113b. Epub 2015 Jul 14.

38.

Helping the Help for CD8+ T Cell Responses.

Amigorena S.

Cell. 2015 Sep 10;162(6):1210-2. doi: 10.1016/j.cell.2015.08.051.

39.

Cross-Presentation in Mouse and Human Dendritic Cells.

Segura E, Amigorena S.

Adv Immunol. 2015;127:1-31. doi: 10.1016/bs.ai.2015.03.002. Epub 2015 Apr 8. Review.

PMID:
26073982
40.

Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate.

Gerber PP, Cabrini M, Jancic C, Paoletti L, Banchio C, von Bilderling C, Sigaut L, Pietrasanta LI, Duette G, Freed EO, Basile Gde S, Moita CF, Moita LF, Amigorena S, Benaroch P, Geffner J, Ostrowski M.

J Cell Biol. 2015 May 11;209(3):435-52. doi: 10.1083/jcb.201409082. Epub 2015 May 4.

41.

Editorial overview: innate immunity.

Chen ZJ, Amigorena S.

Curr Opin Immunol. 2015 Feb;32:v-vi. doi: 10.1016/j.coi.2015.01.016. Epub 2015 Feb 7. No abstract available.

PMID:
25669839
42.

Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity.

Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF.

Cancer Cell. 2014 Dec 8;26(6):938. doi: 10.1016/j.ccell.2014.11.010. Epub 2014 Dec 8. No abstract available.

43.

Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.

Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF.

Cancer Cell. 2014 Nov 10;26(5):638-52. doi: 10.1016/j.ccell.2014.09.007. Epub 2014 Oct 16.

44.

TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation.

Mantegazza AR, Zajac AL, Twelvetrees A, Holzbaur EL, Amigorena S, Marks MS.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15508-13. doi: 10.1073/pnas.1412998111. Epub 2014 Oct 13.

45.

Autologous dendritic cells prolong allograft survival through Tmem176b-dependent antigen cross-presentation.

Segovia M, Louvet C, Charnet P, Savina A, Tilly G, Gautreau L, Carretero-Iglesia L, Beriou G, Cebrian I, Cens T, Hepburn L, Chiffoleau E, Floto RA, Anegon I, Amigorena S, Hill M, Cuturi MC.

Am J Transplant. 2014 May;14(5):1021-1031. doi: 10.1111/ajt.12708. Epub 2014 Apr 14.

46.

[Inflammatory dendritic cells].

Segura E, Amigorena S.

Med Sci (Paris). 2014 Jan;30(1):64-8. doi: 10.1051/medsci/20143001015. Epub 2014 Jan 24. Review. French.

47.

Cross-presentation by human dendritic cell subsets.

Segura E, Amigorena S.

Immunol Lett. 2014 Mar-Apr;158(1-2):73-8. doi: 10.1016/j.imlet.2013.12.001. Epub 2013 Dec 12. Review.

PMID:
24333339
48.

Inflammatory dendritic cells in mice and humans.

Segura E, Amigorena S.

Trends Immunol. 2013 Sep;34(9):440-5. doi: 10.1016/j.it.2013.06.001. Epub 2013 Jul 4. Review.

49.

Identification of human inflammatory dendritic cells.

Segura E, Amigorena S.

Oncoimmunology. 2013 May 1;2(5):e23851.

50.

Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells.

Segura E, Durand M, Amigorena S.

J Exp Med. 2013 May 6;210(5):1035-47. doi: 10.1084/jem.20121103. Epub 2013 Apr 8.

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