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Items: 13


A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.

Hyer ML, Milhollen MA, Ciavarri J, Fleming P, Traore T, Sappal D, Huck J, Shi J, Gavin J, Brownell J, Yang Y, Stringer B, Griffin R, Bruzzese F, Soucy T, Duffy J, Rabino C, Riceberg J, Hoar K, Lublinsky A, Menon S, Sintchak M, Bump N, Pulukuri SM, Langston S, Tirrell S, Kuranda M, Veiby P, Newcomb J, Li P, Wu JT, Powe J, Dick LR, Greenspan P, Galvin K, Manfredi M, Claiborne C, Amidon BS, Bence NF.

Nat Med. 2018 Feb;24(2):186-193. doi: 10.1038/nm.4474. Epub 2018 Jan 15.


Validation of autonomic and endocrine reactivity to a laboratory stressor in young children.

Roos LE, Giuliano RJ, Beauchamp KG, Gunnar M, Amidon B, Fisher PA.

Psychoneuroendocrinology. 2017 Mar;77:51-55. doi: 10.1016/j.psyneuen.2016.11.023. Epub 2016 Nov 29.


KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism.

Chattopadhyay N, Berger AJ, Koenig E, Bannerman B, Garnsey J, Bernard H, Hales P, Maldonado Lopez A, Yang Y, Donelan J, Jordan K, Tirrell S, Stringer B, Xia C, Hather G, Galvin K, Manfredi M, Rhodes N, Amidon B.

PLoS One. 2015 Dec 28;10(12):e0144825. doi: 10.1371/journal.pone.0144825. eCollection 2015.


Plk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell lines.

Driscoll DL, Chakravarty A, Bowman D, Shinde V, Lasky K, Shi J, Vos T, Stringer B, Amidon B, D'Amore N, Hyer ML.

PLoS One. 2014 Nov 3;9(11):e111060. doi: 10.1371/journal.pone.0111060. eCollection 2014.


MLN0905, a small-molecule plk1 inhibitor, induces antitumor responses in human models of diffuse large B-cell lymphoma.

Shi JQ, Lasky K, Shinde V, Stringer B, Qian MG, Liao D, Liu R, Driscoll D, Nestor MT, Amidon BS, Rao Y, Duffey MO, Manfredi MG, Vos TJ, D' Amore N, Hyer ML.

Mol Cancer Ther. 2012 Sep;11(9):2045-53. doi: 10.1158/1535-7163.MCT-11-1036. Epub 2012 May 18.


Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924.

Milhollen MA, Thomas MP, Narayanan U, Traore T, Riceberg J, Amidon BS, Bence NF, Bolen JB, Brownell J, Dick LR, Loke HK, McDonald AA, Ma J, Manfredi MG, Sells TB, Sintchak MD, Yang X, Xu Q, Koenig EM, Gavin JM, Smith PG.

Cancer Cell. 2012 Mar 20;21(3):388-401. doi: 10.1016/j.ccr.2012.02.009.


Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6.

Gavin JM, Chen JJ, Liao H, Rollins N, Yang X, Xu Q, Ma J, Loke HK, Lingaraj T, Brownell JE, Mallender WD, Gould AE, Amidon BS, Dick LR.

J Biol Chem. 2012 May 4;287(19):15512-22. doi: 10.1074/jbc.M111.336198. Epub 2012 Mar 15.


Inhibition of NEDD8-activating enzyme induces rereplication and apoptosis in human tumor cells consistent with deregulating CDT1 turnover.

Milhollen MA, Narayanan U, Soucy TA, Veiby PO, Smith PG, Amidon B.

Cancer Res. 2011 Apr 15;71(8):3042-51. doi: 10.1158/0008-5472.CAN-10-2122. Epub 2011 Apr 12.


Microarray approach for cloned library quality assessment and the comprehensive identification of positives from library screens.

Blackman RK, Amidon BS.

Biotechniques. 2004 Oct;37(4):536, 538, 540. No abstract available.


Transacylase and phospholipases in the synthesis of bis(monoacylglycero)phosphate.

Amidon B, Brown A, Waite M.

Biochemistry. 1996 Nov 5;35(44):13995-4002.


Stereospecific labeling of the glycerol moiety: synthesis of 1,2-dioleoyl-sn-[3-3H]glycero-3-phospho(1-rac-glycerol).

Schmitt JD, Amidon B, Wykle RL, Waite M.

Chem Phys Lipids. 1995 Aug 25;77(2):131-7.


Biosynthetic conversion of phosphatidylglycerol to sn-1:sn-1' bis(monoacylglycerol) phosphate in a macrophage-like cell line.

Amidon B, Schmitt JD, Thuren T, King L, Waite M.

Biochemistry. 1995 Apr 25;34(16):5554-60.


Correlation of weight, length, and time factors in fetal age.


Am J Obstet Gynecol. 1951 Jan;61(1):193-6. No abstract available.


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