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Items: 39


YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation.

Noce V, Battistelli C, Cozzolino AM, Consalvi V, Cicchini C, Strippoli R, Tripodi M, Marchetti A, Amicone L.

Cell Death Dis. 2019 Oct 10;10(10):768. doi: 10.1038/s41419-019-2000-8.


TGFβ Impairs HNF1α Functional Activity in Epithelial-to-Mesenchymal Transition Interfering With the Recruitment of CBP/p300 Acetyltransferases.

Bisceglia F, Battistelli C, Noce V, Montaldo C, Zammataro A, Strippoli R, Tripodi M, Amicone L, Marchetti A.

Front Pharmacol. 2019 Aug 30;10:942. doi: 10.3389/fphar.2019.00942. eCollection 2019.


Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma.

Amicone L, Marchetti A.

Transl Gastroenterol Hepatol. 2018 May 2;3:24. doi: 10.21037/tgh.2018.04.05. eCollection 2018. Review.


Analysis of clinical diagnosis for all patients receiving antenatal betamethasone in a community hospital.

Hannah DM, Taboada CD, Tressler TB, Martinez FJ, Amicone LA, Wert Y.

J Neonatal Perinatal Med. 2018;11(3):295-303. doi: 10.3233/NPM-17127.


TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure.

De Santis Puzzonia M, Cozzolino AM, Grassi G, Bisceglia F, Strippoli R, Guarguaglini G, Citarella F, Sacchetti B, Tripodi M, Marchetti A, Amicone L.

PLoS One. 2016 Nov 28;11(11):e0167158. doi: 10.1371/journal.pone.0167158. eCollection 2016.


The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition.

Battistelli C, Cicchini C, Santangelo L, Tramontano A, Grassi L, Gonzalez FJ, de Nonno V, Grassi G, Amicone L, Tripodi M.

Oncogene. 2017 Feb 16;36(7):942-955. doi: 10.1038/onc.2016.260. Epub 2016 Jul 25.


Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes.

Cozzolino AM, Noce V, Battistelli C, Marchetti A, Grassi G, Cicchini C, Tripodi M, Amicone L.

Stem Cells Int. 2016;2016:5481493. doi: 10.1155/2016/5481493. Epub 2016 Jan 12.


Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis.

Strippoli R, Moreno-Vicente R, Battistelli C, Cicchini C, Noce V, Amicone L, Marchetti A, Del Pozo MA, Tripodi M.

Stem Cells Int. 2016;2016:3543678. doi: 10.1155/2016/3543678. Epub 2016 Jan 31. Review.


Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29.

Cicchini C, de Nonno V, Battistelli C, Cozzolino AM, De Santis Puzzonia M, Ciafrè SA, Brocker C, Gonzalez FJ, Amicone L, Tripodi M.

Biochim Biophys Acta. 2015 Aug;1849(8):919-29. doi: 10.1016/j.bbagrm.2015.05.005. Epub 2015 May 21.


Epigenetic regulation in hepatocellular carcinoma requires long noncoding RNAs.

Amicone L, Citarella F, Cicchini C.

Biomed Res Int. 2015;2015:473942. doi: 10.1155/2015/473942. Epub 2015 Mar 10. Review.


Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte.

Cicchini C, Amicone L, Alonzi T, Marchetti A, Mancone C, Tripodi M.

Liver Int. 2015 Feb;35(2):302-10. doi: 10.1111/liv.12577. Epub 2014 May 20. Review.


Spike-in SILAC proteomic approach reveals the vitronectin as an early molecular signature of liver fibrosis in hepatitis C infections with hepatic iron overload.

Montaldo C, Mattei S, Baiocchini A, Rotiroti N, Del Nonno F, Pucillo LP, Cozzolino AM, Battistelli C, Amicone L, Ippolito G, van Noort V, Conigliaro A, Alonzi T, Tripodi M, Mancone C.

Proteomics. 2014 May;14(9):1107-15. doi: 10.1002/pmic.201300422.


Evidence for a common progenitor of epithelial and mesenchymal components of the liver.

Conigliaro A, Amicone L, Costa V, De Santis Puzzonia M, Mancone C, Sacchetti B, Cicchini C, Garibaldi F, Brenner DA, Kisseleva T, Bianco P, Tripodi M.

Cell Death Differ. 2013 Aug;20(8):1116-23. doi: 10.1038/cdd.2013.49. Epub 2013 May 17.


Human haemato-endothelial precursors: cord blood CD34+ cells produce haemogenic endothelium.

Pelosi E, Castelli G, Martin-Padura I, Bordoni V, Santoro S, Conigliaro A, Cerio AM, De Santis Puzzonia M, Marighetti P, Biffoni M, Alonzi T, Amicone L, Alcalay M, Bertolini F, Testa U, Tripodi M.

PLoS One. 2012;7(12):e51109. doi: 10.1371/journal.pone.0051109. Epub 2012 Dec 4.


Ferritin heavy chain is the host factor responsible for HCV-induced inhibition of apoB-100 production and is required for efficient viral infection.

Mancone C, Montaldo C, Santangelo L, Di Giacomo C, Costa V, Amicone L, Ippolito G, Pucillo LP, Alonzi T, Tripodi M.

J Proteome Res. 2012 May 4;11(5):2786-97. doi: 10.1021/pr201128s. Epub 2012 Apr 10.


An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs.

Garibaldi F, Cicchini C, Conigliaro A, Santangelo L, Cozzolino AM, Grassi G, Marchetti A, Tripodi M, Amicone L.

Cell Death Differ. 2012 Jun;19(6):937-46. doi: 10.1038/cdd.2011.175. Epub 2011 Dec 2.


The new murine hepatic 3A cell line responds to stress stimuli by activating an efficient Unfolded Protein Response (UPR).

Guantario B, Conigliaro A, Amicone L, Sambuy Y, Bellovino D.

Toxicol In Vitro. 2012 Feb;26(1):7-15. doi: 10.1016/j.tiv.2011.09.020. Epub 2011 Oct 4.


The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4α.

Santangelo L, Marchetti A, Cicchini C, Conigliaro A, Conti B, Mancone C, Bonzo JA, Gonzalez FJ, Alonzi T, Amicone L, Tripodi M.

Hepatology. 2011 Jun;53(6):2063-74. doi: 10.1002/hep.24280.


Hepatitis C virus production requires apolipoprotein A-I and affects its association with nascent low-density lipoproteins.

Mancone C, Steindler C, Santangelo L, Simonte G, Vlassi C, Longo MA, D'Offizi G, Di Giacomo C, Pucillo LP, Amicone L, Tripodi M, Alonzi T.

Gut. 2011 Mar;60(3):378-86. doi: 10.1136/gut.2010.211292. Epub 2010 Oct 12.


Proteomic analysis reveals a major role for contact inhibition in the terminal differentiation of hepatocytes.

Mancone C, Conti B, Amicone L, Bordoni V, Cicchini C, Calvo L, Perdomo AB, Fimia GM, Tripodi M, Alonzi T.

J Hepatol. 2010 Feb;52(2):234-43. doi: 10.1016/j.jhep.2009.11.013. Epub 2009 Nov 25.


Convergence of Wnt signaling on the HNF4alpha-driven transcription in controlling liver zonation.

Colletti M, Cicchini C, Conigliaro A, Santangelo L, Alonzi T, Pasquini E, Tripodi M, Amicone L.

Gastroenterology. 2009 Aug;137(2):660-72. doi: 10.1053/j.gastro.2009.05.038. Epub 2009 May 18. Erratum in: Gastroenterology. 2010 Feb;138(2):793.


Elucidation of lipoprotein particles structure by proteomic analysis.

Alonzi T, Mancone C, Amicone L, Tripodi M.

Expert Rev Proteomics. 2008 Feb;5(1):91-104. doi: 10.1586/14789450.5.1.91. Review.


TGFbeta-induced EMT requires focal adhesion kinase (FAK) signaling.

Cicchini C, Laudadio I, Citarella F, Corazzari M, Steindler C, Conigliaro A, Fantoni A, Amicone L, Tripodi M.

Exp Cell Res. 2008 Jan 1;314(1):143-52. Epub 2007 Sep 18.


Isolation and characterization of a murine resident liver stem cell.

Conigliaro A, Colletti M, Cicchini C, Guerra MT, Manfredini R, Zini R, Bordoni V, Siepi F, Leopizzi M, Tripodi M, Amicone L.

Cell Death Differ. 2008 Jan;15(1):123-33. Epub 2007 Oct 12.


Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF.

Mancone C, Amicone L, Fimia GM, Bravo E, Piacentini M, Tripodi M, Alonzi T.

Proteomics. 2007 Jan;7(1):143-54.


Steatosis and intrahepatic lymphocyte recruitment in hepatitis C virus transgenic mice.

Alonzi T, Agrati C, Costabile B, Cicchini C, Amicone L, Cavallari C, Rocca CD, Folgori A, Fipaldini C, Poccia F, Monica N, Tripodi M.

J Gen Virol. 2004 Jun;85(Pt 6):1509-1520. doi: 10.1099/vir.0.19724-0.


Cell-based assay for the detection of chemically induced cellular stress by immortalized untransformed transgenic hepatocytes.

Sacco MG, Amicone L, Catò EM, Filippini D, Vezzoni P, Tripodi M.

BMC Biotechnol. 2004 Mar 19;4:5.


Searching for DNA-protein interactions by lambda phage display.

Cicchini C, Ansuini H, Amicone L, Alonzi T, Nicosia A, Cortese R, Tripodi M, Luzzago A.

J Mol Biol. 2002 Sep 27;322(4):697-706.


Synergy between truncated c-Met (cyto-Met) and c-Myc in liver oncogenesis: importance of TGF-beta signalling in the control of liver homeostasis and transformation.

Amicone L, Terradillos O, Calvo L, Costabile B, Cicchini C, Della Rocca C, Lozupone F, Piacentini M, Buendia MA, Tripodi M.

Oncogene. 2002 Feb 21;21(9):1335-45.


Oxidation affects the regulation of hepatic lipid synthesis by chylomicron remnants.

Napolitano M, Rivabene R, Avella M, Amicone L, Tripodi M, Botham KM, Bravo E.

Free Radic Biol Med. 2001 Mar 1;30(5):506-15.


MMH cells: An in vitro model for the study of retinol-binding protein secretion regulated by retinol.

Bellovino D, Lanyau Y, Garaguso I, Amicone L, Cavallari C, Tripodi M, Gaetani S.

J Cell Physiol. 1999 Oct;181(1):24-32.


Hematopoietic support and cytokine expression of murine-stable hepatocyte cell lines (MMH).

Aiuti A, Cicchini C, Bernardini S, Fedele G, Amicone L, Fantoni A, Tripodi M.

Hepatology. 1998 Dec;28(6):1645-54.


Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes.

Amicone L, Spagnoli FM, Späth G, Giordano S, Tommasini C, Bernardini S, De Luca V, Della Rocca C, Weiss MC, Comoglio PM, Tripodi M.

EMBO J. 1997 Feb 3;16(3):495-503.


Temporal and tissue-specific expression of the MET ORF driven by the complete transcriptional unit of human A1AT gene in transgenic mice.

Amicone L, Galimi MA, Spagnoli FM, Tommasini C, De Luca V, Tripodi M.

Gene. 1995 Sep 11;162(2):323-8.


Evaluation of a transgenic mouse model for alpha-1-antitrypsin (AAT) related liver disease.

Ali R, Perfumo S, della Rocca C, Amicone L, Pozzi L, McCullagh P, Millward-Sadler H, Edwards Y, Povey S, Tripodi M.

Ann Hum Genet. 1994 Oct;58(4):305-20.


Recognition efficiency of the hepatitis B virus polyadenylation signals is tissue specific in transgenic mice.

Perfumo S, Amicone L, Colloca S, Giorgio M, Pozzi L, Tripodi M.

J Virol. 1992 Nov;66(11):6819-23.


Generation of small mutation in large genomic fragments by homologous recombination: description of the technique and examples of its use.

Tripodi M, Perfumo S, Ali R, Amicone L, Abbott C, Cortese R.

Nucleic Acids Res. 1990 Nov 11;18(21):6247-51.


Molecular studies on DNA sequences coding for factor VII and factor XII of human coagulation.

Tripodi M, Citarella F, Guida S, Galeffi P, Gallo E, Ferrazza P, Amicone L, Mariani R, Longobardi C, Fantoni A.

Ital J Biochem. 1986 Sep-Oct;35(5):328-32.


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