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Items: 1 to 50 of 282


Drug-encapsulated carbon (DECON): A novel platform for enhanced drug delivery.

Yadavalli T, Ames J, Agelidis A, Suryawanshi R, Jaishankar D, Hopkins J, Thakkar N, Koujah L, Shukla D.

Sci Adv. 2019 Aug 14;5(8):eaax0780. doi: 10.1126/sciadv.aax0780. eCollection 2019 Aug.


Infection and Fever in Pregnancy and Autism Spectrum Disorders: Findings from the Study to Explore Early Development.

Croen LA, Qian Y, Ashwood P, Zerbo O, Schendel D, Pinto-Martin J, Daniele Fallin M, Levy S, Schieve LA, Yeargin-Allsopp M, Sabourin KR, Ames JL.

Autism Res. 2019 Oct;12(10):1551-1561. doi: 10.1002/aur.2175. Epub 2019 Jul 17.


Expression of different ParE toxins results in conserved phenotypes with distinguishable classes of toxicity.

Ames JR, Muthuramalingam M, Murphy T, Najar FZ, Bourne CR.

Microbiologyopen. 2019 Jul 16:e902. doi: 10.1002/mbo3.902. [Epub ahead of print]


A major role for noncoding regulatory mutations in the evolution of enzyme activity.

Loehlin DW, Ames JR, Vaccaro K, Carroll SB.

Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12383-12389. doi: 10.1073/pnas.1904071116. Epub 2019 May 31.


Conformational Dynamics Underlies Different Functions of Human KDM7 Histone Demethylases.

Chaturvedi SS, Ramanan R, Waheed SO, Ainsley J, Evison M, Ames JM, Schofield CJ, Karabencheva-Christova TG, Christov CZ.

Chemistry. 2019 Apr 11;25(21):5422-5426. doi: 10.1002/chem.201900492. Epub 2019 Mar 26.


Chemical shift assignments of a calmodulin intermediate with two Ca2+ bound in complex with the IQ-motif of voltage-gated Ca2+ channels (CaV1.2).

Salveson I, Anderson DE, Hell JW, Ames JB.

Biomol NMR Assign. 2019 Apr;13(1):233-237. doi: 10.1007/s12104-019-09883-0. Epub 2019 Feb 20.


Conformational flexibility influences structure-function relationships in nucleic acid N-methyl demethylases.

Waheed SO, Ramanan R, Chaturvedi SS, Ainsley J, Evison M, Ames JM, Schofield CJ, Christov CZ, Karabencheva-Christova TG.

Org Biomol Chem. 2019 Feb 20;17(8):2223-2231. doi: 10.1039/c9ob00162j.


Chemical shift assignments of retinal guanylyl cyclase activating protein 5 (GCAP5).

Cudia D, Ames JB.

Biomol NMR Assign. 2019 Apr;13(1):201-205. doi: 10.1007/s12104-019-09877-y. Epub 2019 Jan 31.


In utero dioxin exposure and cardiometabolic risk in the Seveso Second Generation Study.

Warner M, Rauch S, Ames J, Mocarelli P, Brambilla P, Signorini S, Eskenazi B.

Int J Obes (Lond). 2019 Jan 18. doi: 10.1038/s41366-018-0306-8. [Epub ahead of print]


Prenatal dioxin exposure and neuropsychological functioning in the Seveso Second Generation Health Study.

Ames J, Warner M, Siracusa C, Signorini S, Brambilla P, Mocarelli P, Eskenazi B.

Int J Hyg Environ Health. 2019 Apr;222(3):425-433. doi: 10.1016/j.ijheh.2018.12.009. Epub 2019 Jan 9.


Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle.

Peshenko IV, Yu Q, Lim S, Cudia D, Dizhoor AM, Ames JB.

J Biol Chem. 2019 Feb 15;294(7):2318-2328. doi: 10.1074/jbc.RA118.006106. Epub 2018 Dec 17.


Dimerization of Neuronal Calcium Sensor Proteins.

Ames JB.

Front Mol Neurosci. 2018 Nov 2;11:397. doi: 10.3389/fnmol.2018.00397. eCollection 2018. Review.


The toxin from a ParDE toxin-antitoxin system found in Pseudomonas aeruginosa offers protection to cells challenged with anti-gyrase antibiotics.

Muthuramalingam M, White JC, Murphy T, Ames JR, Bourne CR.

Mol Microbiol. 2019 Feb;111(2):441-454. doi: 10.1111/mmi.14165. Epub 2018 Dec 5.


The Seveso accident: A look at 40 years of health research and beyond.

Eskenazi B, Warner M, Brambilla P, Signorini S, Ames J, Mocarelli P.

Environ Int. 2018 Dec;121(Pt 1):71-84. doi: 10.1016/j.envint.2018.08.051. Epub 2018 Sep 1. Review.


AHR gene-dioxin interactions and birthweight in the Seveso Second Generation Health Study.

Ames J, Warner M, Mocarelli P, Brambilla P, Signorini S, Siracusa C, Huen K, Holland N, Eskenazi B.

Int J Epidemiol. 2018 Dec 1;47(6):1992-2004. doi: 10.1093/ije/dyy165.


Impact of advanced detector technology and iterative reconstruction on low-dose quantitative assessment of lung computed tomography density in a biological lung model.

Hammond E, Chan KS, Ames JC, Stoyles N, Sloan CM, Guo J, Newell JD Jr, Hoffman EA, Sieren JC.

Med Phys. 2018 Jun 21. doi: 10.1002/mp.13057. [Epub ahead of print]


Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4.

Lim S, Yu Q, Gottlieb SM, Chang CW, Rockwell NC, Martin SS, Madsen D, Lagarias JC, Larsen DS, Ames JB.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):4387-4392. doi: 10.1073/pnas.1720682115. Epub 2018 Apr 9.


Retinal guanylyl cyclase activating protein 1 forms a functional dimer.

Lim S, Roseman G, Peshenko I, Manchala G, Cudia D, Dizhoor AM, Millhauser G, Ames JB.

PLoS One. 2018 Mar 7;13(3):e0193947. doi: 10.1371/journal.pone.0193947. eCollection 2018.


Weighing the Anti-Ischemic Benefits and Bleeding Risks from Aspirin Therapy: a Rational Approach.

Dugani S, Ames JM, Manson JE, Mora S.

Curr Atheroscler Rep. 2018 Feb 21;20(3):15. doi: 10.1007/s11883-018-0717-y. Review.


An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye.

Jaishankar D, Yakoub AM, Yadavalli T, Agelidis A, Thakkar N, Hadigal S, Ames J, Shukla D.

Sci Transl Med. 2018 Feb 14;10(428). pii: eaan5861. doi: 10.1126/scitranslmed.aan5861.


α-Actinin Anchors PSD-95 at Postsynaptic Sites.

Matt L, Kim K, Hergarden AC, Patriarchi T, Malik ZA, Park DK, Chowdhury D, Buonarati OR, Henderson PB, Gökçek Saraç Ç, Zhang Y, Mohapatra D, Horne MC, Ames JB, Hell JW.

Neuron. 2018 Mar 7;97(5):1094-1109.e9. doi: 10.1016/j.neuron.2018.01.036. Epub 2018 Feb 8.


Extraosseous Multiple Myeloma: Case Report of Presentation in the Lower Extremity Soft Tissues with Literature Review.

Ames J, Al-Samaraee A, Takahashi T.

Case Rep Radiol. 2017;2017:9159035. doi: 10.1155/2017/9159035. Epub 2017 Dec 17.


Chemical shift assignments of retinal degeneration 3 protein (RD3).

Lim S, Cudia D, Yu Q, Peshenko I, Dizhoor AM, Ames JB.

Biomol NMR Assign. 2018 Apr;12(1):167-170. doi: 10.1007/s12104-018-9802-y. Epub 2018 Jan 11.


Neurocognitive and physical functioning in the Seveso Women's Health Study.

Ames J, Warner M, Brambilla P, Mocarelli P, Satariano WA, Eskenazi B.

Environ Res. 2018 Apr;162:55-62. doi: 10.1016/j.envres.2017.12.005. Epub 2017 Dec 26.


Structural Characterization of Ferrous Ion Binding to Retinal Guanylate Cyclase Activator Protein 5 from Zebrafish Photoreceptors.

Lim S, Scholten A, Manchala G, Cudia D, Zlomke-Sell SK, Koch KW, Ames JB.

Biochemistry. 2017 Dec 26;56(51):6652-6661. doi: 10.1021/acs.biochem.7b01029. Epub 2017 Dec 7.


Ca2+/calmodulin binding to PSD-95 mediates homeostatic synaptic scaling down.

Chowdhury D, Turner M, Patriarchi T, Hergarden AC, Anderson D, Zhang Y, Sun J, Chen CY, Ames JB, Hell JW.

EMBO J. 2018 Jan 4;37(1):122-138. doi: 10.15252/embj.201695829. Epub 2017 Nov 8.


Detection of femoroplasty on pre- and post-arthroscopic comparison radiographs following treatment of femoroacetabular impingement syndrome: multi-reader accuracy and agreement study.

Haider SJ, Siegel AH, Spratt KF, Ames JB, Graham JA, Cheung YY.

Skeletal Radiol. 2018 Feb;47(2):233-242. doi: 10.1007/s00256-017-2789-0. Epub 2017 Nov 6.


Use of minimally invasive spine surgical instruments for the treatment of bone tumors.

Reeves RA, DeWolf MC, Shaughnessy PJ, Ames JB, Henderson ER.

Expert Rev Med Devices. 2017 Nov;14(11):881-890. doi: 10.1080/17434440.2017.1386549. Epub 2017 Oct 4. Review.


A biologically inspired image classifier: adaptive feature detection.

Ames JC, Michmizos KP.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:3334-3337. doi: 10.1109/EMBC.2016.7591441.


Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α.

Li Z, Zhang Y, Hedman AC, Ames JB, Sacks DB.

J Biol Chem. 2017 Mar 17;292(11):4614-4622. doi: 10.1074/jbc.M116.754804. Epub 2017 Feb 7.


Structure and Calcium Binding Properties of a Neuronal Calcium-Myristoyl Switch Protein, Visinin-Like Protein 3.

Li C, Lim S, Braunewell KH, Ames JB.

PLoS One. 2016 Nov 7;11(11):e0165921. doi: 10.1371/journal.pone.0165921. eCollection 2016.


Herpes Simplex Virus 1 Induces Phosphorylation and Reorganization of Lamin A/C through the γ134.5 Protein That Facilitates Nuclear Egress.

Wu S, Pan S, Zhang L, Baines J, Roller R, Ames J, Yang M, Wang J, Chen D, Liu Y, Zhang C, Cao Y, He B.

J Virol. 2016 Oct 28;90(22):10414-10422. doi: 10.1128/JVI.01392-16. Print 2016 Nov 15.


Predictive Big Data Analytics: A Study of Parkinson's Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations.

Dinov ID, Heavner B, Tang M, Glusman G, Chard K, Darcy M, Madduri R, Pa J, Spino C, Kesselman C, Foster I, Deutsch EW, Price ND, Van Horn JD, Ames J, Clark K, Hood L, Hampstead BM, Dauer W, Toga AW.

PLoS One. 2016 Aug 5;11(8):e0157077. doi: 10.1371/journal.pone.0157077. eCollection 2016.


Inactivation of RNA Viruses by Gamma Irradiation: A Study on Mitigating Factors.

Hume AJ, Ames J, Rennick LJ, Duprex WP, Marzi A, Tonkiss J, Mühlberger E.

Viruses. 2016 Jul 22;8(7). pii: E204. doi: 10.3390/v8070204.


Low-Dose Aspirin in the Primary Prevention of Cardiovascular Disease: Shared Decision Making in Clinical Practice.

Mora S, Ames JM, Manson JE.

JAMA. 2016 Aug 16;316(7):709-10. doi: 10.1001/jama.2016.8362. No abstract available.


Inhibition of Ovarian Tumor Growth by Targeting the HU177 Cryptic Collagen Epitope.

Caron JM, Ames JJ, Contois L, Liebes L, Friesel R, Muggia F, Vary CP, Oxburgh L, Brooks PC.

Am J Pathol. 2016 Jun;186(6):1649-61. doi: 10.1016/j.ajpath.2016.01.015.


Field data and numerical modeling: A multiple lines of evidence approach for assessing vapor intrusion exposure risks.

Pennell KG, Scammell MK, McClean MD, Suuberg EM, Moradi A, Roghani M, Ames J, Friguglietti L, Indeglia PA, Shen R, Yao Y, Heiger-Bernays WJ.

Sci Total Environ. 2016 Jun 15;556:291-301. doi: 10.1016/j.scitotenv.2016.02.185. Epub 2016 Mar 12.


Chemical shift assignments of the C-terminal EF-hand domain of α-actinin-1.

Turner M, Anderson DE, Rajan S, Hell JW, Ames JB.

Biomol NMR Assign. 2016 Apr;10(1):219-22. doi: 10.1007/s12104-016-9670-2. Epub 2016 Feb 10.


Methods for Analyzing Tumor Angiogenesis in the Chick Chorioallantoic Membrane Model.

Ames JJ, Henderson T, Liaw L, Brooks PC.

Methods Mol Biol. 2016;1406:255-69. doi: 10.1007/978-1-4939-3444-7_22.


Optimization of RGD-Containing Cyclic Peptides against αvβ3 Integrin.

Wang Y, Xiao W, Zhang Y, Meza L, Tseng H, Takada Y, Ames JB, Lam KS.

Mol Cancer Ther. 2016 Feb;15(2):232-40. doi: 10.1158/1535-7163.MCT-15-0544. Epub 2015 Dec 30.


Structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) Mutant V77E in a Ca2+-free/Mg2+-bound Activator State.

Lim S, Peshenko IV, Olshevskaya EV, Dizhoor AM, Ames JB.

J Biol Chem. 2016 Feb 26;291(9):4429-41. doi: 10.1074/jbc.M115.696161. Epub 2015 Dec 24.


Identification of an Endogenously Generated Cryptic Collagen Epitope (XL313) That May Selectively Regulate Angiogenesis by an Integrin Yes-associated Protein (YAP) Mechano-transduction Pathway.

Ames JJ, Contois L, Caron JM, Tweedie E, Yang X, Friesel R, Vary C, Brooks PC.

J Biol Chem. 2016 Feb 5;291(6):2731-50. doi: 10.1074/jbc.M115.669614. Epub 2015 Dec 14.


1H, 13C, and 15N chemical shift assignments of cyanobacteriochrome NpR6012g4 in the green-absorbing photoproduct state.

Lim S, Yu Q, Rockwell NC, Martin SS, Lagarias JC, Ames JB.

Biomol NMR Assign. 2016 Apr;10(1):157-61. doi: 10.1007/s12104-015-9657-4. Epub 2015 Nov 4.


1H, 15N, and 13C chemical shift assignments of cyanobacteriochrome NpR6012g4 in the red-absorbing dark state.

Yu Q, Lim S, Rockwell NC, Martin SS, Clark Lagarias J, Ames JB.

Biomol NMR Assign. 2016 Apr;10(1):139-42. doi: 10.1007/s12104-015-9653-8. Epub 2015 Oct 19.


Big biomedical data as the key resource for discovery science.

Toga AW, Foster I, Kesselman C, Madduri R, Chard K, Deutsch EW, Price ND, Glusman G, Heavner BD, Dinov ID, Ames J, Van Horn J, Kramer R, Hood L.

J Am Med Inform Assoc. 2015 Nov;22(6):1126-31. doi: 10.1093/jamia/ocv077. Epub 2015 Jul 21.


Current trends in medical management of infantile hemangioma.

Ames JA, Sykes JM.

Curr Opin Otolaryngol Head Neck Surg. 2015 Aug;23(4):286-91. doi: 10.1097/MOO.0000000000000170. Review.


Calcium-dependent membrane association of a flagellar calcium sensor does not require calcium binding.

Maric D, Olson CL, Xu X, Ames JB, Engman DM.

Mol Biochem Parasitol. 2015 May;201(1):72-75. doi: 10.1016/j.molbiopara.2015.06.003. Epub 2015 Jun 19.


Role played by Prx1-dependent extracellular matrix properties in vascular smooth muscle development in embryonic lungs.

Ihida-Stansbury K, Ames J, Chokshi M, Aiad N, Sanyal S, Kawabata KC, Levental I, Sundararaghavan HG, Burdick JA, Janmey P, Miyazono K, Wells RG, Jones PL.

Pulm Circ. 2015 Jun;5(2):382-97. doi: 10.1086/681272.


Characterization of Red/Green Cyanobacteriochrome NpR6012g4 by Solution Nuclear Magnetic Resonance Spectroscopy: A Hydrophobic Pocket for the C15-E,anti Chromophore in the Photoproduct.

Rockwell NC, Martin SS, Lim S, Lagarias JC, Ames JB.

Biochemistry. 2015 Jun 23;54(24):3772-83. doi: 10.1021/acs.biochem.5b00438. Epub 2015 Jun 5.


BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses.

Young K, Tweedie E, Conley B, Ames J, FitzSimons M, Brooks P, Liaw L, Vary CP.

PLoS One. 2015 Apr 24;10(4):e0122892. doi: 10.1371/journal.pone.0122892. eCollection 2015.

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