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Items: 29

1.

Inhibition of lysine-specific demethylase LSD1 induces senescence in Glioblastoma cells through a HIF-1α-dependent pathway.

Saccà CD, Gorini F, Ambrosio S, Amente S, Faicchia D, Matarese G, Lania L, Majello B.

Biochim Biophys Acta Gene Regul Mech. 2019 May;1862(5):535-546. doi: 10.1016/j.bbagrm.2019.03.004. Epub 2019 Apr 2.

PMID:
30951900
2.

Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer.

Majello B, Gorini F, Saccà CD, Amente S.

Cancers (Basel). 2019 Mar 7;11(3). pii: E324. doi: 10.3390/cancers11030324. Review.

3.

Genome-wide mapping of 8-oxo-7,8-dihydro-2'-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells.

Amente S, Di Palo G, Scala G, Castrignanò T, Gorini F, Cocozza S, Moresano A, Pucci P, Ma B, Stepanov I, Lania L, Pelicci PG, Dellino GI, Majello B.

Nucleic Acids Res. 2019 Jan 10;47(1):221-236. doi: 10.1093/nar/gky1152.

4.

Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target.

Sapienza MR, Abate F, Melle F, Orecchioni S, Fuligni F, Etebari M, Tabanelli V, Laginestra MA, Pileri A, Motta G, Rossi M, Agostinelli C, Sabattini E, Pimpinelli N, Truni M, Falini B, Cerroni L, Talarico G, Piccioni R, Amente S, Indio V, Tarantino G, Brundu F, Paulli M, Berti E, Facchetti F, Dellino GI, Bertolini F, Tripodo C, Rabadan R, Pileri SA.

Haematologica. 2019 Apr;104(4):729-737. doi: 10.3324/haematol.2018.202093. Epub 2018 Oct 31.

5.

Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway.

Ambrosio S, Saccà CD, Amente S, Paladino S, Lania L, Majello B.

Oncogene. 2017 Nov 30;36(48):6701-6711. doi: 10.1038/onc.2017.267. Epub 2017 Aug 7.

6.

Mitochondrial AKAP1 supports mTOR pathway and tumor growth.

Rinaldi L, Sepe M, Delle Donne R, Conte K, Arcella A, Borzacchiello D, Amente S, De Vita F, Porpora M, Garbi C, Oliva MA, Procaccini C, Faicchia D, Matarese G, Zito Marino F, Rocco G, Pignatiello S, Franco R, Insabato L, Majello B, Feliciello A.

Cell Death Dis. 2017 Jun 1;8(6):e2842. doi: 10.1038/cddis.2017.241.

7.

LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene.

Ambrosio S, Amente S, Saccà CD, Capasso M, Calogero RA, Lania L, Majello B.

Oncotarget. 2017 Jan 17;8(3):3854-3869. doi: 10.18632/oncotarget.12924.

8.

Cell cycle-dependent resolution of DNA double-strand breaks.

Ambrosio S, Di Palo G, Napolitano G, Amente S, Dellino GI, Faretta M, Pelicci PG, Lania L, Majello B.

Oncotarget. 2016 Jan 26;7(4):4949-60. doi: 10.18632/oncotarget.6644.

9.

Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma.

Amente S, Milazzo G, Sorrentino MC, Ambrosio S, Di Palo G, Lania L, Perini G, Majello B.

Oncotarget. 2015 Jun 10;6(16):14572-83.

10.

MYC impairs resolution of site-specific DNA double-strand breaks repair.

Ambrosio S, Amente S, Napolitano G, Di Palo G, Lania L, Majello B.

Mutat Res. 2015 Apr;774:6-13. doi: 10.1016/j.mrfmmm.2015.02.005. Epub 2015 Mar 4.

PMID:
25770827
11.

Sequence-specific double strand breaks trigger P-TEFb-dependent Rpb1-CTD hyperphosphorylation.

Napolitano G, Amente S, Lavadera ML, Di Palo G, Ambrosio S, Lania L, Dellino GI, Pelicci PG, Majello B.

Mutat Res. 2013 Sep;749(1-2):21-7. doi: 10.1016/j.mrfmmm.2013.07.005. Epub 2013 Jul 29.

12.

The histone LSD1 demethylase in stemness and cancer transcription programs.

Amente S, Lania L, Majello B.

Biochim Biophys Acta. 2013 Oct;1829(10):981-6. doi: 10.1016/j.bbagrm.2013.05.002. Epub 2013 May 16. Review.

13.

Identification of novel AR-targeted microRNAs mediating androgen signalling through critical pathways to regulate cell viability in prostate cancer.

Mo W, Zhang J, Li X, Meng D, Gao Y, Yang S, Wan X, Zhou C, Guo F, Huang Y, Amente S, Avvedimento EV, Xie Y, Li Y.

PLoS One. 2013;8(2):e56592. doi: 10.1371/journal.pone.0056592. Epub 2013 Feb 22.

14.

Cu-Zn superoxide dismutase activates muscarinic acetylcholine M1 receptor pathway in neuroblastoma cells.

Damiano S, Petrozziello T, Ucci V, Amente S, Santillo M, Mondola P.

Mol Cell Neurosci. 2013 Jan;52:31-7. doi: 10.1016/j.mcn.2012.11.001. Epub 2012 Nov 10.

PMID:
23147108
15.

SUMO-activating SAE1 transcription is positively regulated by Myc.

Amente S, Lavadera ML, Palo GD, Majello B.

Am J Cancer Res. 2012;2(3):330-4. Epub 2012 Apr 21.

16.

Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.

Damiano S, Fusco R, Morano A, De Mizio M, Paternò R, De Rosa A, Spinelli R, Amente S, Frunzio R, Mondola P, Miot F, Laccetti P, Santillo M, Avvedimento EV.

PLoS One. 2012;7(4):e34405. doi: 10.1371/journal.pone.0034405. Epub 2012 Apr 16.

17.

Epigenetic reprogramming of Myc target genes.

Amente S, Lania L, Majello B.

Am J Cancer Res. 2011;1(3):413-418. Epub 2011 Feb 6.

18.

Myc and PI3K/AKT signaling cooperatively repress FOXO3a-dependent PUMA and GADD45a gene expression.

Amente S, Zhang J, Lavadera ML, Lania L, Avvedimento EV, Majello B.

Nucleic Acids Res. 2011 Dec;39(22):9498-507. doi: 10.1093/nar/gkr638. Epub 2011 Aug 10. Erratum in: Nucleic Acids Res. 2014 Feb;42(3):2098.

19.

DNA oxidation drives Myc mediated transcription.

Amente S, Lania L, Avvedimento EV, Majello B.

Cell Cycle. 2010 Aug 1;9(15):3002-4. doi: 10.4161/cc.9.15.12499. Review.

PMID:
20714214
20.

Caffeine prevents transcription inhibition and P-TEFb/7SK dissociation following UV-induced DNA damage.

Napolitano G, Amente S, Castiglia V, Gargano B, Ruda V, Darzacq X, Bensaude O, Majello B, Lania L.

PLoS One. 2010 Jun 21;5(6):e11245. doi: 10.1371/journal.pone.0011245.

21.

Reactive oxygen species, Ki-Ras, and mitochondrial superoxide dismutase cooperate in nerve growth factor-induced differentiation of PC12 cells.

Cassano S, Agnese S, D'Amato V, Papale M, Garbi C, Castagnola P, Ruocco MR, Castellano I, De Vendittis E, Santillo M, Amente S, Porcellini A, Avvedimento EV.

J Biol Chem. 2010 Jul 30;285(31):24141-53. doi: 10.1074/jbc.M109.098525. Epub 2010 May 21.

22.

LSD1-mediated demethylation of histone H3 lysine 4 triggers Myc-induced transcription.

Amente S, Bertoni A, Morano A, Lania L, Avvedimento EV, Majello B.

Oncogene. 2010 Jun 24;29(25):3691-702. doi: 10.1038/onc.2010.120. Epub 2010 Apr 26.

PMID:
20418916
23.

Camptothecin releases P-TEFb from the inactive 7SK snRNP complex.

Amente S, Gargano B, Napolitano G, Lania L, Majello B.

Cell Cycle. 2009 Apr 15;8(8):1249-55. Epub 2009 Apr 24.

PMID:
19305131
24.

p14ARF is capable of promoting HIV-1 tat degradation.

Gargano B, Fiorillo M, Amente S, Majello B, Lania L.

Cell Cycle. 2008 May 15;7(10):1433-9. Epub 2008 Feb 28.

PMID:
18418067
25.

P-TEFb is a crucial co-factor for Myc transactivation.

Gargano B, Amente S, Majello B, Lania L.

Cell Cycle. 2007 Aug 15;6(16):2031-7. Epub 2007 Jun 5.

PMID:
17700062
26.

p14ARF interacts with N-Myc and inhibits its transcriptional activity.

Amente S, Gargano B, Diolaiti D, Della Valle G, Lania L, Majello B.

FEBS Lett. 2007 Mar 6;581(5):821-5. Epub 2007 Feb 2.

27.

p14ARF directly interacts with Myc through the Myc BoxII domain.

Amente S, Gargano B, Varrone F, Ruggiero L, Dominguez-Sola D, Lania L, Majello B.

Cancer Biol Ther. 2006 Mar;5(3):287-91. Epub 2006 Mar 8.

PMID:
16410719
28.
29.

The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP.

Licciardo P, Amente S, Ruggiero L, Monti M, Pucci P, Lania L, Majello B.

Nucleic Acids Res. 2003 Feb 1;31(3):999-1005.

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