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Items: 1 to 50 of 80

1.

Six2 regulates Pax9 expression, palatogenesis and craniofacial bone formation.

Sweat YY, Sweat M, Mansaray M, Cao H, Eliason S, Adeyemo WL, Gowans LJJ, Eshete MA, Anand D, Chalkley C, Saadi I, Lachke SA, Butali A, Amendt BA.

Dev Biol. 2019 Nov 23. pii: S0012-1606(19)30492-0. doi: 10.1016/j.ydbio.2019.11.010. [Epub ahead of print]

PMID:
31765609
2.

Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.

Gowans LJJ, Cameron-Christie S, Slayton RL, Busch T, Romero-Bustillos M, Eliason S, Sweat M, Sobreira N, Yu W, Kantaputra PN, Wohler E, Adeyemo WL, Lachke SA, Anand D, Campbell C, Drummond BK, Markie DM, van Vuuren WJ, van Vuuren LJ, Casamassimo PS, Ettinger R, Owais A, van Staden I, Amendt BA, Adeyemo AA, Murray JC, Robertson SP, Butali A.

Front Genet. 2019 Sep 20;10:800. doi: 10.3389/fgene.2019.00800. eCollection 2019.

3.

Enhancement of MicroRNA-200c on Osteogenic Differentiation and Bone Regeneration by Targeting Sox2-Mediated Wnt Signaling and Klf4.

Akkouch A, Eliason S, Sweat ME, Romero-Bustillos M, Zhu M, Qian F, Amendt BA, Hong L.

Hum Gene Ther. 2019 Nov;30(11):1405-1418. doi: 10.1089/hum.2019.019. Epub 2019 Aug 16.

PMID:
31288577
4.

MicroRNA-200c Attenuates Periodontitis by Modulating Proinflammatory and Osteoclastogenic Mediators.

Akkouch A, Zhu M, Romero-Bustillos M, Eliason S, Qian F, Salem AK, Amendt BA, Hong L.

Stem Cells Dev. 2019 Aug 1;28(15):1026-1036. doi: 10.1089/scd.2019.0027. Epub 2019 May 20.

PMID:
31017046
5.

The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation.

Kousa YA, Zhu H, Fakhouri WD, Lei Y, Kinoshita A, Roushangar RR, Patel NK, Agopian AJ, Yang W, Leslie EJ, Busch TD, Mansour TA, Li X, Smith AL, Li EB, Sharma DB, Williams TJ, Chai Y, Amendt BA, Liao EC, Mitchell LE, Bassuk AG, Gregory S, Ashley-Koch A, Shaw GM, Finnell RH, Schutte BC.

Hum Mol Genet. 2019 May 15;28(10):1726-1737. doi: 10.1093/hmg/ddz010.

PMID:
30689861
6.

Genomic analyses in African populations identify novel risk loci for cleft palate.

Butali A, Mossey PA, Adeyemo WL, Eshete MA, Gowans LJJ, Busch TD, Jain D, Yu W, Huan L, Laurie CA, Laurie CC, Nelson S, Li M, Sanchez-Lara PA, Magee WP, Magee KS, Auslander A, Brindopke F, Kay DM, Caggana M, Romitti PA, Mills JL, Audu R, Onwuamah C, Oseni GO, Owais A, James O, Olaitan PB, Aregbesola BS, Braimah RO, Oginni FO, Oladele AO, Bello SA, Rhodes J, Shiang R, Donkor P, Obiri-Yeboah S, Arthur FKN, Twumasi P, Agbenorku P, Plange-Rhule G, Oti AA, Ogunlewe OM, Oladega AA, Adekunle AA, Erinoso AO, Adamson OO, Elufowoju AA, Ayelomi OI, Hailu T, Hailu A, Demissie Y, Derebew M, Eliason S, Romero-Bustillous M, Lo C, Park J, Desai S, Mohammed M, Abate F, Abdur-Rahman LO, Anand D, Saadi I, Oladugba AV, Lachke SA, Amendt BA, Rotimi CN, Marazita ML, Cornell RA, Murray JC, Adeyemo AA.

Hum Mol Genet. 2019 Mar 15;28(6):1038-1051. doi: 10.1093/hmg/ddy402.

PMID:
30452639
7.

FoxO6 regulates Hippo signaling and growth of the craniofacial complex.

Sun Z, da Fontoura CSG, Moreno M, Holton NE, Sweat M, Sweat Y, Lee MK, Arbon J, Bidlack FB, Thedens DR, Nopoulos P, Cao H, Eliason S, Weinberg SM, Martin JF, Moreno-Uribe L, Amendt BA.

PLoS Genet. 2018 Oct 4;14(10):e1007675. doi: 10.1371/journal.pgen.1007675. eCollection 2018 Oct.

8.

Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development.

Williams MA, Biguetti C, Romero-Bustillos M, Maheshwari K, Dinckan N, Cavalla F, Liu X, Silva R, Akyalcin S, Uyguner ZO, Vieira AR, Amendt BA, Fakhouri WD, Letra A.

Sci Rep. 2018 Feb 14;8(1):2979. doi: 10.1038/s41598-018-21368-z.

9.

Alteration of mitochondrial biogenesis promotes disease progression in multiple myeloma.

Zhan X, Yu W, Franqui-Machin R, Bates ML, Nadiminti K, Cao H, Amendt BA, Jethava Y, Frech I, Zhan F, Tricot G.

Oncotarget. 2017 Nov 27;8(67):111213-111224. doi: 10.18632/oncotarget.22740. eCollection 2017 Dec 19.

10.

Plasticity within the niche ensures the maintenance of a Sox2+ stem cell population in the mouse incisor.

Sanz-Navarro M, Seidel K, Sun Z, Bertonnier-Brouty L, Amendt BA, Klein OD, Michon F.

Development. 2018 Jan 8;145(1). pii: dev155929. doi: 10.1242/dev.155929.

11.

Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation.

Yu W, Li X, Eliason S, Romero-Bustillos M, Ries RJ, Cao H, Amendt BA.

Dev Biol. 2017 Sep 1;429(1):44-55. doi: 10.1016/j.ydbio.2017.07.011. Epub 2017 Jul 23.

12.

Inhibition of the miR-17-92 Cluster Separates Stages of Palatogenesis.

Ries RJ, Yu W, Holton N, Cao H, Amendt BA.

J Dent Res. 2017 Oct;96(11):1257-1264. doi: 10.1177/0022034517716915. Epub 2017 Jun 29.

13.

Candidate gene analyses of 3-dimensional dentoalveolar phenotypes in subjects with malocclusion.

Weaver CA, Miller SF, da Fontoura CS, Wehby GL, Amendt BA, Holton NE, Allareddy V, Southard TE, Moreno Uribe LM.

Am J Orthod Dentofacial Orthop. 2017 Mar;151(3):539-558. doi: 10.1016/j.ajodo.2016.08.027.

14.

Mesenchymal MicroRNA Function Branches Out.

Cao H, Hong L, Amendt BA.

Dev Cell. 2017 Jan 9;40(1):1-2. doi: 10.1016/j.devcel.2016.12.018.

15.

Correction: MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation.

Hong L, Sharp T, Khorsand B, Fischer C, Eliason S, Salem AK, Akkouch A, Brogden K, Amendt BA.

PLoS One. 2016 Dec 29;11(12):e0169381. doi: 10.1371/journal.pone.0169381. eCollection 2016.

16.

Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal.

Sun Z, Yu W, Sanz Navarro M, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, Michon F, Klein OD, Chai Y, Dupuy A, Engelhardt JF, Chen Z, Amendt BA.

Development. 2016 Nov 15;143(22):4115-4126. Epub 2016 Sep 22.

17.

MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation.

Hong L, Sharp T, Khorsand B, Fischer C, Eliason S, Salem A, Akkouch A, Brogden K, Amendt BA.

PLoS One. 2016 Aug 16;11(8):e0160915. doi: 10.1371/journal.pone.0160915. eCollection 2016. Erratum in: PLoS One. 2016 Dec 29;11(12 ):e0169381.

18.

A new plasmid-based microRNA inhibitor system that inhibits microRNA families in transgenic mice and cells: a potential new therapeutic reagent.

Cao H, Yu W, Li X, Wang J, Gao S, Holton NE, Eliason S, Sharp T, Amendt BA.

Gene Ther. 2016 Jul;23(7):634. doi: 10.1038/gt.2016.44. No abstract available.

PMID:
27383391
19.

pySAPC, a python package for sparse affinity propagation clustering: Application to odontogenesis whole genome time series gene-expression data.

Cao H, Amendt BA.

Biochim Biophys Acta. 2016 Nov;1860(11 Pt B):2613-8. doi: 10.1016/j.bbagen.2016.06.008. Epub 2016 Jun 8.

PMID:
27288587
20.

Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury.

Tao G, Kahr PC, Morikawa Y, Zhang M, Rahmani M, Heallen TR, Li L, Sun Z, Olson EN, Amendt BA, Martin JF.

Nature. 2016 Jun 2;534(7605):119-23. doi: 10.1038/nature17959. Epub 2016 May 25.

21.

A new plasmid-based microRNA inhibitor system that inhibits microRNA families in transgenic mice and cells: a potential new therapeutic reagent.

Cao H, Yu W, Li X, Wang J, Gao S, Holton NE, Eliason S, Sharp T, Amendt BA.

Gene Ther. 2016 Jun;23(6):527-42. doi: 10.1038/gt.2016.22. Epub 2016 Mar 2. Erratum in: Gene Ther. 2016 Jul;23 (7):634.

22.

Bioactive nanofibers enable the identification of thrombospondin 2 as a key player in enamel regeneration.

Huang Z, Newcomb CJ, Lei Y, Zhou Y, Bornstein P, Amendt BA, Stupp SI, Snead ML.

Biomaterials. 2015 Aug;61:216-28. doi: 10.1016/j.biomaterials.2015.05.035. Epub 2015 May 19.

23.

Candidate Gene Analyses of Skeletal Variation in Malocclusion.

da Fontoura CS, Miller SF, Wehby GL, Amendt BA, Holton NE, Southard TE, Allareddy V, Moreno Uribe LM.

J Dent Res. 2015 Jul;94(7):913-20. doi: 10.1177/0022034515581643. Epub 2015 Apr 24.

24.

TBX1 protein interactions and microRNA-96-5p regulation controls cell proliferation during craniofacial and dental development: implications for 22q11.2 deletion syndrome.

Gao S, Moreno M, Eliason S, Cao H, Li X, Yu W, Bidlack FB, Margolis HC, Baldini A, Amendt BA.

Hum Mol Genet. 2015 Apr 15;24(8):2330-48. doi: 10.1093/hmg/ddu750. Epub 2015 Jan 2.

25.

A pituitary homeobox 2 (Pitx2):microRNA-200a-3p:β-catenin pathway converts mesenchymal cells to amelogenin-expressing dental epithelial cells.

Sharp T, Wang J, Li X, Cao H, Gao S, Moreno M, Amendt BA.

J Biol Chem. 2014 Sep 26;289(39):27327-41. doi: 10.1074/jbc.M114.575654. Epub 2014 Aug 13.

26.

MicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression.

Zhang Z, Kim K, Li X, Moreno M, Sharp T, Goodheart MJ, Safe S, Dupuy AJ, Amendt BA.

Mol Cancer Ther. 2014 Jul;13(7):1942-51. doi: 10.1158/1535-7163.MCT-13-1000. Epub 2014 Apr 30.

27.

Understanding the role of Tbx1 as a candidate gene for 22q11.2 deletion syndrome.

Gao S, Li X, Amendt BA.

Curr Allergy Asthma Rep. 2013 Dec;13(6):613-21. doi: 10.1007/s11882-013-0384-6. Review.

28.

A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome.

Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA.

Hum Mol Genet. 2014 Jan 1;23(1):194-208. doi: 10.1093/hmg/ddt411. Epub 2013 Aug 23.

29.

The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation.

Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus MT, Klein OD, Amendt BA.

Development. 2013 Aug;140(16):3348-59. doi: 10.1242/dev.089193. Epub 2013 Jul 17.

30.

Differentiation of human dental stem cells reveals a role for microRNA-218.

Gay I, Cavender A, Peto D, Sun Z, Speer A, Cao H, Amendt BA.

J Periodontal Res. 2014 Feb;49(1):110-20. doi: 10.1111/jre.12086. Epub 2013 May 13.

31.

Protein inhibitors of activated STAT (Pias1 and Piasy) differentially regulate pituitary homeobox 2 (PITX2) transcriptional activity.

Wang J, Sun Z, Zhang Z, Saadi I, Wang J, Li X, Gao S, Engle JJ, Kuburas A, Fu X, Yu W, Klein WH, Russo AF, Amendt BA.

J Biol Chem. 2013 May 3;288(18):12580-95. doi: 10.1074/jbc.M112.374561. Epub 2013 Mar 20.

32.

Dact2 represses PITX2 transcriptional activation and cell proliferation through Wnt/beta-catenin signaling during odontogenesis.

Li X, Florez S, Wang J, Cao H, Amendt BA.

PLoS One. 2013;8(1):e54868. doi: 10.1371/journal.pone.0054868. Epub 2013 Jan 22.

33.

The LIM homeodomain transcription factor LHX6: a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2) to regulate odontogenesis.

Zhang Z, Gutierrez D, Li X, Bidlack F, Cao H, Wang J, Andrade K, Margolis HC, Amendt BA.

J Biol Chem. 2013 Jan 25;288(4):2485-500. doi: 10.1074/jbc.M112.402933. Epub 2012 Dec 10.

34.

An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud.

Jumlongras D, Lachke SA, O'Connell DJ, Aboukhalil A, Li X, Choe SE, Ho JW, Turbe-Doan A, Robertson EA, Olsen BR, Bulyk ML, Amendt BA, Maas RL.

PLoS One. 2012;7(6):e38568. doi: 10.1371/journal.pone.0038568. Epub 2012 Jun 12.

35.

Effects of dietary fish oil on the depletion of carcinogenic PAH-DNA adduct levels in the liver of B6C3F1 mouse.

Zhou GD, Zhu H, Phillips TD, Wang J, Wang SZ, Wang F, Amendt BA, Couroucli XI, Donnelly KC, Moorthy B.

PLoS One. 2011;6(10):e26589. doi: 10.1371/journal.pone.0026589. Epub 2011 Oct 31.

36.

Fuz regulates craniofacial development through tissue specific responses to signaling factors.

Zhang Z, Wlodarczyk BJ, Niederreither K, Venugopalan S, Florez S, Finnell RH, Amendt BA.

PLoS One. 2011;6(9):e24608. doi: 10.1371/journal.pone.0024608. Epub 2011 Sep 14.

37.

Hierarchical interactions of homeodomain and forkhead transcription factors in regulating odontogenic gene expression.

Venugopalan SR, Li X, Amen MA, Florez S, Gutierrez D, Cao H, Wang J, Amendt BA.

J Biol Chem. 2011 Jun 17;286(24):21372-83. doi: 10.1074/jbc.M111.252031. Epub 2011 Apr 19.

38.

Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21.

Cao H, Florez S, Amen M, Huynh T, Skobe Z, Baldini A, Amendt BA.

Dev Biol. 2010 Nov 15;347(2):289-300. doi: 10.1016/j.ydbio.2010.08.031. Epub 2010 Sep 15.

39.

MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression.

Zhang Z, Florez S, Gutierrez-Hartmann A, Martin JF, Amendt BA.

J Biol Chem. 2010 Nov 5;285(45):34718-28. doi: 10.1074/jbc.M110.126441. Epub 2010 Aug 31.

40.

MicroRNAs play a critical role in tooth development.

Cao H, Wang J, Li X, Florez S, Huang Z, Venugopalan SR, Elangovan S, Skobe Z, Margolis HC, Martin JF, Amendt BA.

J Dent Res. 2010 Aug;89(8):779-84. doi: 10.1177/0022034510369304. Epub 2010 May 26.

41.

Chromatin protein HMGB2 regulates articular cartilage surface maintenance via beta-catenin pathway.

Taniguchi N, Caramés B, Kawakami Y, Amendt BA, Komiya S, Lotz M.

Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16817-22. doi: 10.1073/pnas.0904414106. Epub 2009 Sep 10.

42.

The Pitx2c N-terminal domain is a critical interaction domain required for asymmetric morphogenesis.

Simard A, Di Giorgio L, Amen M, Westwood A, Amendt BA, Ryan AK.

Dev Dyn. 2009 Oct;238(10):2459-70. doi: 10.1002/dvdy.22062.

43.

Bone marrow cells produce a novel TSHbeta splice variant that is upregulated in the thyroid following systemic virus infection.

Vincent BH, Montufar-Solis D, Teng BB, Amendt BA, Schaefer J, Klein JR.

Genes Immun. 2009 Jan;10(1):18-26. doi: 10.1038/gene.2008.69. Epub 2008 Aug 28.

44.

Novel expression and transcriptional regulation of FoxJ1 during oro-facial morphogenesis.

Venugopalan SR, Amen MA, Wang J, Wong L, Cavender AC, D'Souza RN, Akerlund M, Brody SL, Hjalt TA, Amendt BA.

Hum Mol Genet. 2008 Dec 1;17(23):3643-54. doi: 10.1093/hmg/ddn258. Epub 2008 Aug 22.

45.

Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation.

Shang Y, Yoshida T, Amendt BA, Martin JF, Owens GK.

J Cell Biol. 2008 May 5;181(3):461-73. doi: 10.1083/jcb.200711145.

46.

Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.

Weng J, Luo J, Cheng X, Jin C, Zhou X, Qu J, Tu L, Ai D, Li D, Wang J, Martin JF, Amendt BA, Liu M.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6081-6. doi: 10.1073/pnas.0708257105. Epub 2008 Apr 18.

47.

Chromatin-associated HMG-17 is a major regulator of homeodomain transcription factor activity modulated by Wnt/beta-catenin signaling.

Amen M, Espinoza HM, Cox C, Liang X, Wang J, Link TM, Brennan RG, Martin JF, Amendt BA.

Nucleic Acids Res. 2008 Feb;36(2):462-76. Epub 2007 Nov 27.

48.

PITX2 and beta-catenin interactions regulate Lef-1 isoform expression.

Amen M, Liu X, Vadlamudi U, Elizondo G, Diamond E, Engelhardt JF, Amendt BA.

Mol Cell Biol. 2007 Nov;27(21):7560-73. Epub 2007 Sep 4.

49.

Nuclear factor 1 and T-cell factor/LEF recognition elements regulate Pitx2 transcription in pituitary development.

Ai D, Wang J, Amen M, Lu MF, Amendt BA, Martin JF.

Mol Cell Biol. 2007 Aug;27(16):5765-75. Epub 2007 Jun 11.

50.

Functional interactions between Dlx2 and lymphoid enhancer factor regulate Msx2.

Diamond E, Amen M, Hu Q, Espinoza HM, Amendt BA.

Nucleic Acids Res. 2006;34(20):5951-65. Epub 2006 Oct 26.

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