Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35

1.

A Novel Phenotype Links HIV-1 Capsid Stability to cGAS-Mediated DNA Sensing.

Siddiqui MA, Saito A, Halambage UD, Ferhadian D, Fischer DK, Francis AC, Melikyan GB, Ambrose Z, Aiken C, Yamashita M.

J Virol. 2019 Jul 30;93(16). pii: e00706-19. doi: 10.1128/JVI.00706-19. Print 2019 Aug 15.

PMID:
31167922
2.

Two Coselected Distal Mutations in HIV-1 Reverse Transcriptase (RT) Alter Susceptibility to Nonnucleoside RT Inhibitors and Nucleoside Analogs.

Boyer PL, Melody K, Smith SJ, Dunn LL, Kline C, Fischer DK, Dwivedi R, Clark P, Hughes SH, Ambrose Z.

J Virol. 2019 May 15;93(11). pii: e00224-19. doi: 10.1128/JVI.00224-19. Print 2019 Jun 1.

3.

CA Mutation N57A Has Distinct Strain-Specific HIV-1 Capsid Uncoating and Infectivity Phenotypes.

Fischer DK, Saito A, Kline C, Cohen R, Watkins SC, Yamashita M, Ambrose Z.

J Virol. 2019 Apr 17;93(9). pii: e00214-19. doi: 10.1128/JVI.00214-19. Print 2019 May 1.

PMID:
30814280
4.

Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid.

Ning J, Zhong Z, Fischer DK, Harris G, Watkins SC, Ambrose Z, Zhang P.

J Virol. 2018 Jun 13;92(13). pii: e00368-18. doi: 10.1128/JVI.00368-18. Print 2018 Jul 1.

5.

Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon.

Akiyama H, Ramirez NP, Gibson G, Kline C, Watkins S, Ambrose Z, Gummuluru S.

J Virol. 2017 Oct 13;91(21). pii: e00972-17. doi: 10.1128/JVI.00972-17. Print 2017 Nov 1.

6.

A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.

Feder AF, Kline C, Polacino P, Cottrell M, Kashuba ADM, Keele BF, Hu SL, Petrov DA, Pennings PS, Ambrose Z.

PLoS Pathog. 2017 May 25;13(5):e1006358. doi: 10.1371/journal.ppat.1006358. eCollection 2017 May.

7.

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.

Zerbato JM, Serrao E, Lenzi G, Kim B, Ambrose Z, Watkins SC, Engelman AN, Sluis-Cremer N.

J Virol. 2016 Aug 26;90(18):8059-73. doi: 10.1128/JVI.00553-16. Print 2016 Sep 15.

8.

Rilpivirine and Doravirine Have Complementary Efficacies Against NNRTI-Resistant HIV-1 Mutants.

Smith SJ, Pauly GT, Akram A, Melody K, Ambrose Z, Schneider JP, Hughes SH.

J Acquir Immune Defic Syndr. 2016 Aug 15;72(5):485-91. doi: 10.1097/QAI.0000000000001031.

9.

Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants.

Smith SJ, Pauly GT, Akram A, Melody K, Rai G, Maloney DJ, Ambrose Z, Thomas CJ, Schneider JT, Hughes SH.

Retrovirology. 2016 Feb 16;13:11. doi: 10.1186/s12977-016-0244-2.

10.

Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy.

Kearney MF, Anderson EM, Coomer C, Smith L, Shao W, Johnson N, Kline C, Spindler J, Mellors JW, Coffin JM, Ambrose Z.

Retrovirology. 2015 Nov 11;12:93. doi: 10.1186/s12977-015-0212-2.

11.

Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase.

Melody K, McBeth S, Kline C, Kashuba AD, Mellors JW, Ambrose Z.

Antimicrob Agents Chemother. 2015 Dec;59(12):7762-70. doi: 10.1128/AAC.01937-15. Epub 2015 Oct 5.

12.

Visualization and quantification of simian immunodeficiency virus-infected cells using non-invasive molecular imaging.

Song J, Cai Z, White AG, Jin T, Wang X, Kadayakkara D, Anderson CJ, Ambrose Z, Young WB.

J Gen Virol. 2015 Oct;96(10):3131-42. doi: 10.1099/jgv.0.000245. Epub 2015 Jul 14.

13.

Dysregulation of multiple inflammatory molecules in lymph node and ileum of macaques during RT-SHIV infection with or without antiretroviral therapy.

Ambrose Z, Kline C, Polacino P, Hu SL.

J Med Primatol. 2014 Oct;43(5):298-309. doi: 10.1111/jmp.12126. Epub 2014 May 2.

14.

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins.

Ambrose Z, Aiken C.

Virology. 2014 Apr;454-455:371-9. doi: 10.1016/j.virol.2014.02.004. Epub 2014 Feb 20. Review.

15.

Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model.

Kline C, Ndjomou J, Franks T, Kiser R, Coalter V, Smedley J, Piatak M Jr, Mellors JW, Lifson JD, Ambrose Z.

PLoS One. 2013 Dec 18;8(12):e84275. doi: 10.1371/journal.pone.0084275. eCollection 2013.

16.

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay.

Xu H, Franks T, Gibson G, Huber K, Rahm N, Strambio De Castillia C, Luban J, Aiken C, Watkins S, Sluis-Cremer N, Ambrose Z.

Retrovirology. 2013 Jul 9;10:70. doi: 10.1186/1742-4690-10-70.

17.

Ultrasensitive allele-specific PCR reveals rare preexisting drug-resistant variants and a large replicating virus population in macaques infected with a simian immunodeficiency virus containing human immunodeficiency virus reverse transcriptase.

Boltz VF, Ambrose Z, Kearney MF, Shao W, Kewalramani VN, Maldarelli F, Mellors JW, Coffin JM.

J Virol. 2012 Dec;86(23):12525-30. doi: 10.1128/JVI.01963-12. Epub 2012 Aug 29.

18.

Identification of HIV inhibitors guided by free energy perturbation calculations.

Acevedo O, Ambrose Z, Flaherty PT, Aamer H, Jain P, Sambasivarao SV.

Curr Pharm Des. 2012;18(9):1199-216. Review.

19.

Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection.

Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN.

J Virol. 2012 Apr;86(8):4708-14. doi: 10.1128/JVI.05887-11. Epub 2012 Feb 1.

20.

Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography.

Jun S, Ke D, Debiec K, Zhao G, Meng X, Ambrose Z, Gibson GA, Watkins SC, Zhang P.

Structure. 2011 Nov 9;19(11):1573-81. doi: 10.1016/j.str.2011.09.006.

21.

Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy.

Kearney M, Spindler J, Shao W, Maldarelli F, Palmer S, Hu SL, Lifson JD, KewalRamani VN, Mellors JW, Coffin JM, Ambrose Z.

J Virol. 2011 Jan;85(2):1067-76. doi: 10.1128/JVI.01701-10. Epub 2010 Nov 17.

22.

Flexible use of nuclear import pathways by HIV-1.

Lee K, Ambrose Z, Martin TD, Oztop I, Mulky A, Julias JG, Vandegraaff N, Baumann JG, Wang R, Yuen W, Takemura T, Shelton K, Taniuchi I, Li Y, Sodroski J, Littman DR, Coffin JM, Hughes SH, Unutmaz D, Engelman A, KewalRamani VN.

Cell Host Microbe. 2010 Mar 18;7(3):221-33. doi: 10.1016/j.chom.2010.02.007.

23.

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy.

Shao W, Kearney M, Maldarelli F, Mellors JW, Stephens RM, Lifson JD, KewalRamani VN, Ambrose Z, Coffin JM, Palmer SE.

Retrovirology. 2009 Nov 4;6:101. doi: 10.1186/1742-4690-6-101.

24.

The nucleoside analogue D-carba T blocks HIV-1 reverse transcription.

Boyer PL, Vu BC, Ambrose Z, Julias JG, Warnecke S, Liao C, Meier C, Marquez VE, Hughes SH.

J Med Chem. 2009 Sep 10;52(17):5356-64. doi: 10.1021/jm801176e.

25.

A macaque model of HIV-1 infection.

Hatziioannou T, Ambrose Z, Chung NP, Piatak M Jr, Yuan F, Trubey CM, Coalter V, Kiser R, Schneider D, Smedley J, Pung R, Gathuka M, Estes JD, Veazey RS, KewalRamani VN, Lifson JD, Bieniasz PD.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4425-9. doi: 10.1073/pnas.0812587106. Epub 2009 Mar 2.

26.

The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs.

Ambrose Z, Herman BD, Sheen CW, Zelina S, Moore KL, Tachedjian G, Nissley DV, Sluis-Cremer N.

J Virol. 2009 Apr;83(8):3826-33. doi: 10.1128/JVI.01968-08. Epub 2009 Feb 4.

27.

Incomplete protection against simian immunodeficiency virus vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges.

Ambrose Z, Compton L, Piatak M Jr, Lu D, Alvord WG, Lubomirski MS, Hildreth JE, Lifson JD, Miller CJ, KewalRamani VN.

J Virol. 2008 Jul;82(13):6591-9. doi: 10.1128/JVI.02730-07. Epub 2008 Apr 23.

28.

Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy.

Ambrose Z, Palmer S, Boltz VF, Kearney M, Larsen K, Polacino P, Flanary L, Oswald K, Piatak M Jr, Smedley J, Shao W, Bischofberger N, Maldarelli F, Kimata JT, Mellors JW, Hu SL, Coffin JM, Lifson JD, KewalRamani VN.

J Virol. 2007 Nov;81(22):12145-55. Epub 2007 Sep 12.

29.

The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants.

Boyer PL, Julias JG, Ambrose Z, Siddiqui MA, Marquez VE, Hughes SH.

J Mol Biol. 2007 Aug 24;371(4):873-82. Epub 2007 May 18.

PMID:
17597154
30.

HIV/AIDS: in search of an animal model.

Ambrose Z, KewalRamani VN, Bieniasz PD, Hatziioannou T.

Trends Biotechnol. 2007 Aug;25(8):333-7. Epub 2007 Jun 18. Review.

PMID:
17574286
31.

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

Nissley DV, Radzio J, Ambrose Z, Sheen CW, Hamamouch N, Moore KL, Tachedjian G, Sluis-Cremer N.

Biochem J. 2007 May 15;404(1):151-7.

34.

Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6).

Ambrose Z, Thompson J, Larsen K, Kuller L, Panicali DL, Clements JD, Agy M, Montefiori DC, Hu SL, Bosch ML.

Virology. 2003 Mar 30;308(1):178-90.

35.

Supplemental Content

Loading ...
Support Center