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Items: 17


Adjacency-constrained hierarchical clustering of a band similarity matrix with application to genomics.

Ambroise C, Dehman A, Neuvial P, Rigaill G, Vialaneix N.

Algorithms Mol Biol. 2019 Nov 15;14:22. doi: 10.1186/s13015-019-0157-4. eCollection 2019.


Systematic analysis of TruSeq, SMARTer and SMARTer Ultra-Low RNA-seq kits for standard, low and ultra-low quantity samples.

Palomares MA, Dalmasso C, Bonnet E, Derbois C, Brohard-Julien S, Ambroise C, Battail C, Deleuze JF, Olaso R.

Sci Rep. 2019 May 17;9(1):7550. doi: 10.1038/s41598-019-43983-0.


Learning the optimal scale for GWAS through hierarchical SNP aggregation.

Guinot F, Szafranski M, Ambroise C, Samson F.

BMC Bioinformatics. 2018 Nov 29;19(1):459. doi: 10.1186/s12859-018-2475-9.


Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation.

O'Neill BT, Beck EM, Butler CR, Nolan CE, Gonzales C, Zhang L, Doran SD, Lapham K, Buzon LM, Dutra JK, Barreiro G, Hou X, Martinez-Alsina LA, Rogers BN, Villalobos A, Murray JC, Ogilvie K, LaChapelle EA, Chang C, Lanyon LF, Steppan CM, Robshaw A, Hales K, Boucher GG, Pandher K, Houle C, Ambroise CW, Karanian D, Riddell D, Bales KR, Brodney MA.

J Med Chem. 2018 May 24;61(10):4476-4504. doi: 10.1021/acs.jmedchem.8b00246. Epub 2018 Apr 17.


Eigen-Epistasis for detecting gene-gene interactions.

Stanislas V, Dalmasso C, Ambroise C.

BMC Bioinformatics. 2017 Jan 23;18(1):54. doi: 10.1186/s12859-017-1488-0.


Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors.

Zuhl AM, Nolan CE, Brodney MA, Niessen S, Atchison K, Houle C, Karanian DA, Ambroise C, Brulet JW, Beck EM, Doran SD, O'Neill BT, Am Ende CW, Chang C, Geoghegan KF, West GM, Judkins JC, Hou X, Riddell DR, Johnson DS.

Nat Commun. 2016 Oct 11;7:13042. doi: 10.1038/ncomms13042.


Performance of a blockwise approach in variable selection using linkage disequilibrium information.

Dehman A, Ambroise C, Neuvial P.

BMC Bioinformatics. 2015 May 8;16:148. doi: 10.1186/s12859-015-0556-6.


Tool compounds robustly increase turnover of an artificial substrate by glucocerebrosidase in human brain lysates.

Berger Z, Perkins S, Ambroise C, Oborski C, Calabrese M, Noell S, Riddell D, Hirst WD.

PLoS One. 2015 Mar 12;10(3):e0119141. doi: 10.1371/journal.pone.0119141. eCollection 2015.


SHIPS: Spectral Hierarchical clustering for the Inference of Population Structure in genetic studies.

Bouaziz M, Paccard C, Guedj M, Ambroise C.

PLoS One. 2012;7(10):e45685. doi: 10.1371/journal.pone.0045685. Epub 2012 Oct 12.


Spirocyclic sulfamides as β-secretase 1 (BACE-1) inhibitors for the treatment of Alzheimer's disease: utilization of structure based drug design, WaterMap, and CNS penetration studies to identify centrally efficacious inhibitors.

Brodney MA, Barreiro G, Ogilvie K, Hajos-Korcsok E, Murray J, Vajdos F, Ambroise C, Christoffersen C, Fisher K, Lanyon L, Liu J, Nolan CE, Withka JM, Borzilleri KA, Efremov I, Oborski CE, Varghese A, O'Neill BT.

J Med Chem. 2012 Nov 8;55(21):9224-39. doi: 10.1021/jm3009426. Epub 2012 Oct 8.


Accounting for population stratification in practice: a comparison of the main strategies dedicated to genome-wide association studies.

Bouaziz M, Ambroise C, Guedj M.

PLoS One. 2011;6(12):e28845. doi: 10.1371/journal.pone.0028845. Epub 2011 Dec 21.


Weighted-LASSO for structured network inference from time course data.

Charbonnier C, Chiquet J, Ambroise C.

Stat Appl Genet Mol Biol. 2010;9:Article 15. doi: 10.2202/1544-6115.1519. Epub 2010 Feb 1.


The B73 maize genome: complexity, diversity, and dynamics.

Schnable PS, Ware D, Fulton RS, Stein JC, Wei F, Pasternak S, Liang C, Zhang J, Fulton L, Graves TA, Minx P, Reily AD, Courtney L, Kruchowski SS, Tomlinson C, Strong C, Delehaunty K, Fronick C, Courtney B, Rock SM, Belter E, Du F, Kim K, Abbott RM, Cotton M, Levy A, Marchetto P, Ochoa K, Jackson SM, Gillam B, Chen W, Yan L, Higginbotham J, Cardenas M, Waligorski J, Applebaum E, Phelps L, Falcone J, Kanchi K, Thane T, Scimone A, Thane N, Henke J, Wang T, Ruppert J, Shah N, Rotter K, Hodges J, Ingenthron E, Cordes M, Kohlberg S, Sgro J, Delgado B, Mead K, Chinwalla A, Leonard S, Crouse K, Collura K, Kudrna D, Currie J, He R, Angelova A, Rajasekar S, Mueller T, Lomeli R, Scara G, Ko A, Delaney K, Wissotski M, Lopez G, Campos D, Braidotti M, Ashley E, Golser W, Kim H, Lee S, Lin J, Dujmic Z, Kim W, Talag J, Zuccolo A, Fan C, Sebastian A, Kramer M, Spiegel L, Nascimento L, Zutavern T, Miller B, Ambroise C, Muller S, Spooner W, Narechania A, Ren L, Wei S, Kumari S, Faga B, Levy MJ, McMahan L, Van Buren P, Vaughn MW, Ying K, Yeh CT, Emrich SJ, Jia Y, Kalyanaraman A, Hsia AP, Barbazuk WB, Baucom RS, Brutnell TP, Carpita NC, Chaparro C, Chia JM, Deragon JM, Estill JC, Fu Y, Jeddeloh JA, Han Y, Lee H, Li P, Lisch DR, Liu S, Liu Z, Nagel DH, McCann MC, SanMiguel P, Myers AM, Nettleton D, Nguyen J, Penning BW, Ponnala L, Schneider KL, Schwartz DC, Sharma A, Soderlund C, Springer NM, Sun Q, Wang H, Waterman M, Westerman R, Wolfgruber TK, Yang L, Yu Y, Zhang L, Zhou S, Zhu Q, Bennetzen JL, Dawe RK, Jiang J, Jiang N, Presting GG, Wessler SR, Aluru S, Martienssen RA, Clifton SW, McCombie WR, Wing RA, Wilson RK.

Science. 2009 Nov 20;326(5956):1112-5. doi: 10.1126/science.1178534. Erratum in: Science. 2012 Aug 31;337(6098):1040.


Identification of functional modules based on transcriptional regulation structure.

Birmelé E, Elati M, Rouveirol C, Ambroise C.

BMC Proc. 2008 Dec 17;2 Suppl 4:S4.


SIMoNe: Statistical Inference for MOdular NEtworks.

Chiquet J, Smith A, Grasseau G, Matias C, Ambroise C.

Bioinformatics. 2009 Feb 1;25(3):417-8. doi: 10.1093/bioinformatics/btn637. Epub 2008 Dec 10.


Selection bias in gene extraction on the basis of microarray gene-expression data.

Ambroise C, McLachlan GJ.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6562-6. Epub 2002 Apr 30.


High-performance liquid chromatographic determination of 3',5'-cyclic adenosine monophosphate in human platelets.

DePetrillo PB, Swift RM, Ambroise C, Abernethy DR.

J Chromatogr. 1990 May 18;527(2):421-7. No abstract available.


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