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Items: 12


Intestinal MUC2 mucin supramolecular topology by packing and release resting on D3 domain assembly.

Nilsson HE, Ambort D, Bäckström M, Thomsson E, Koeck PJB, Hansson GC, Hebert H.

J Mol Biol. 2014 Jul 15;426(14):2567-2579. doi: 10.1016/j.jmb.2014.04.027. Epub 2014 May 8.


Increased understanding of the biochemistry and biosynthesis of MUC2 and other gel-forming mucins through the recombinant expression of their protein domains.

Bäckström M, Ambort D, Thomsson E, Johansson ME, Hansson GC.

Mol Biotechnol. 2013 Jun;54(2):250-6. doi: 10.1007/s12033-012-9562-3.


Perspectives on mucus properties and formation--lessons from the biochemical world.

Ambort D, Johansson ME, Gustafsson JK, Ermund A, Hansson GC.

Cold Spring Harb Perspect Med. 2012 Nov 1;2(11). pii: a014159. doi: 10.1101/cshperspect.a014159. Review.


Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype.

Gustafsson JK, Ermund A, Ambort D, Johansson ME, Nilsson HE, Thorell K, Hebert H, Sjövall H, Hansson GC.

J Exp Med. 2012 Jul 2;209(7):1263-72. doi: 10.1084/jem.20120562. Epub 2012 Jun 18.


Calcium and pH-dependent packing and release of the gel-forming MUC2 mucin.

Ambort D, Johansson ME, Gustafsson JK, Nilsson HE, Ermund A, Johansson BR, Koeck PJ, Hebert H, Hansson GC.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5645-50. doi: 10.1073/pnas.1120269109. Epub 2012 Mar 26.


Composition and functional role of the mucus layers in the intestine.

Johansson ME, Ambort D, Pelaseyed T, Schütte A, Gustafsson JK, Ermund A, Subramani DB, Holmén-Larsson JM, Thomsson KA, Bergström JH, van der Post S, Rodriguez-Piñeiro AM, Sjövall H, Bäckström M, Hansson GC.

Cell Mol Life Sci. 2011 Nov;68(22):3635-41. doi: 10.1007/s00018-011-0822-3. Epub 2011 Sep 25. Review.


Function of the CysD domain of the gel-forming MUC2 mucin.

Ambort D, van der Post S, Johansson ME, Mackenzie J, Thomsson E, Krengel U, Hansson GC.

Biochem J. 2011 May 15;436(1):61-70. doi: 10.1042/BJ20102066.


Specific processing of tenascin-C by the metalloprotease meprinbeta neutralizes its inhibition of cell spreading.

Ambort D, Brellier F, Becker-Pauly C, Stöcker W, Andrejevic-Blant S, Chiquet M, Sterchi EE.

Matrix Biol. 2010 Jan;29(1):31-42. doi: 10.1016/j.matbio.2009.08.007. Epub 2009 Sep 12.


A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin.

Ambort D, Stalder D, Lottaz D, Huguenin M, Oneda B, Heller M, Sterchi EE.

FEBS J. 2008 Sep;275(18):4490-509. doi: 10.1111/j.1742-4658.2008.06592.x. Epub 2008 Jul 30.


Metalloprotease meprin beta in rat kidney: glomerular localization and differential expression in glomerulonephritis.

Oneda B, Lods N, Lottaz D, Becker-Pauly C, Stöcker W, Pippin J, Huguenin M, Ambort D, Marti HP, Sterchi EE.

PLoS One. 2008 May 28;3(5):e2278. doi: 10.1371/journal.pone.0002278.


The metalloprotease meprinbeta processes E-cadherin and weakens intercellular adhesion.

Huguenin M, Müller EJ, Trachsel-Rösmann S, Oneda B, Ambort D, Sterchi EE, Lottaz D.

PLoS One. 2008 May 14;3(5):e2153. doi: 10.1371/journal.pone.0002153.


Sample preparation of culture medium from Madin-Darby canine kidney cells.

Ambort D, Lottaz D, Sterchi E.

Methods Mol Biol. 2008;425:113-30. doi: 10.1007/978-1-60327-210-0_10.


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