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COMP-Ang1 Stabilizes Hyperglycemic Disruption of Blood-Retinal Barrier Phenotype in Human Retinal Microvascular Endothelial Cells.

Rochfort KD, Carroll LS, Barabas P, Curtis TM, Ambati BK, Barron N, Cummins PM.

Invest Ophthalmol Vis Sci. 2019 Aug 1;60(10):3547-3555. doi: 10.1167/iovs.19-27644.


The value of nutritional supplements in treating Age-Related Macular Degeneration: a review of the literature.

Mukhtar S, Ambati BK.

Int Ophthalmol. 2019 Jul 16. doi: 10.1007/s10792-019-01140-6. [Epub ahead of print] Review.


Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina.

Carroll LS, Uehara H, Fang D, Choi S, Zhang X, Singh M, Sandhu Z, Cummins PM, Curtis TM, Stitt AW, Archer BJ, Ambati BK.

Invest Ophthalmol Vis Sci. 2019 Jun 3;60(7):2494-2502. doi: 10.1167/iovs.18-26182.


Maxillary Zoster and Neurotrophic Keratitis following Trigeminal Block.

Cho YK, Kwon J, Pugazhendhi S, Ambati BK.

Case Rep Ophthalmol. 2019 Feb 6;10(1):61-66. doi: 10.1159/000496683. eCollection 2019 Jan-Apr.


Detection of microvascular retinal changes in type I diabetic mice with optical coherence tomography angiography.

Uehara H, Lesuma T, Stocking P, Jensen N, Kumar SR, Zhang MA, Choi S, Zhang X, Archer B, Carroll L, Ambati BK.

Exp Eye Res. 2019 Jan;178:91-98. doi: 10.1016/j.exer.2018.09.017. Epub 2018 Sep 27.


Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice.

Zhang B, Tan L, Yu Y, Wang B, Chen Z, Han J, Li M, Chen J, Xiao T, Ambati BK, Cai L, Yang Q, Nayak NR, Zhang J, Fan X.

Theranostics. 2018 Apr 9;8(10):2765-2781. doi: 10.7150/thno.22904. eCollection 2018.


Epithelial Keratitis After Cataract Surgery.

Cho YK, Kwon JW, Konda S, Ambati BK.

Cornea. 2018 Jun;37(6):755-759. doi: 10.1097/ICO.0000000000001592.


RNA activating-double stranded RNA targeting flt-1 promoter inhibits endothelial cell proliferation through soluble FLT-1 upregulation.

Choi S, Uehara H, Wu Y, Das S, Zhang X, Archer B, Carroll L, Ambati BK.

PLoS One. 2018 Mar 6;13(3):e0193590. doi: 10.1371/journal.pone.0193590. eCollection 2018.


Comparative analysis of the safety and efficacy of intracameral cefuroxime, moxifloxacin and vancomycin at the end of cataract surgery: a meta-analysis.

Bowen RC, Zhou AX, Bondalapati S, Lawyer TW, Snow KB, Evans PR, Bardsley T, McFarland M, Kliethermes M, Shi D, Mamalis CA, Greene T, Rudnisky CJ, Ambati BK.

Br J Ophthalmol. 2018 Sep;102(9):1268-1276. doi: 10.1136/bjophthalmol-2017-311051. Epub 2018 Jan 11.


Pediatric keratoconus: a review of the literature.

Mukhtar S, Ambati BK.

Int Ophthalmol. 2018 Oct;38(5):2257-2266. doi: 10.1007/s10792-017-0699-8. Epub 2017 Aug 29. Review.


Effect of sorafenib in a murine high risk penetrating keratoplasty model.

Cho YK, Shin EY, Uehara H, Ambati BK.

Int J Ophthalmol. 2017 Jun 18;10(6):834-839. doi: 10.18240/ijo.2017.06.02. eCollection 2017.


New capsular tension segment with 2-point fixation for zonular weakness.

Singh MK, Ambati BK, Crandall AS.

J Cataract Refract Surg. 2017 May;43(5):590-592. doi: 10.1016/j.jcrs.2017.04.021.


Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide.

Uehara H, Muddana SK, Zhang X, Das SK, Bhuvanagiri S, Liu J, Wu Y, Choi S, Carroll LS, Archer B, Ambati BK.

Transl Vis Sci Technol. 2017 May 24;6(3):9. doi: 10.1167/tvst.6.3.9. eCollection 2017 May.


Targeted Intraceptor Nanoparticle for Neovascular Macular Degeneration: Preclinical Dose Optimization and Toxicology Assessment.

Zhang X, Bohner A, Bhuvanagiri S, Uehara H, Upadhyay AK, Emerson LL, Bondalapati S, Muddana SK, Fang D, Li M, Sandhu Z, Hussain A, Carroll LS, Tiem M, Archer B, Kompella U, Patil R, Ambati BK.

Mol Ther. 2017 Jul 5;25(7):1606-1615. doi: 10.1016/j.ymthe.2017.01.014. Epub 2017 Feb 22.


Sutureless Lamellar Corneoscleral Patch Graft With Fibrin Sealant for Limbal Dermoid Removal.

Zhou AX, Ambati BK.

J Pediatr Ophthalmol Strabismus. 2016 Jun 3;53 Online:e22-5. doi: 10.3928/01913913-20160509-03.


Risk factors and biomarkers of age-related macular degeneration.

Lambert NG, ElShelmani H, Singh MK, Mansergh FC, Wride MA, Padilla M, Keegan D, Hogg RE, Ambati BK.

Prog Retin Eye Res. 2016 Sep;54:64-102. doi: 10.1016/j.preteyeres.2016.04.003. Epub 2016 May 6. Review.


Hydrogel ocular sealant for wound closure during intrastromal corneal ring segment implantation.

Rai RR, Messenger WB, Ambati BK.

J Cataract Refract Surg. 2016 Apr;42(4):515-9. doi: 10.1016/j.jcrs.2016.03.022.


Intravenous immune globulin suppresses angiogenesis in mice and humans.

Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J.

Signal Transduct Target Ther. 2016;1. pii: 15002. Epub 2016 Jan 28.


Human IgG1 antibodies suppress angiogenesis in a target-independent manner.

Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J.

Signal Transduct Target Ther. 2016;1. pii: 15001. Epub 2016 Jan 28.


Subretinal AAV2.COMP-Ang1 suppresses choroidal neovascularization and vascular endothelial growth factor in a murine model of age-related macular degeneration.

Lambert NG, Zhang X, Rai RR, Uehara H, Choi S, Carroll LS, Das SK, Cahoon JM, Kirk BH, Bentley BM, Ambati BK.

Exp Eye Res. 2016 Apr;145:248-257. doi: 10.1016/j.exer.2016.01.009. Epub 2016 Jan 13.


Safety of undiluted intracameral moxifloxacin without postoperative topical antibiotics in cataract surgery.

Zhou AX, Messenger WB, Sargent S, Ambati BK.

Int Ophthalmol. 2016 Aug;36(4):493-8. doi: 10.1007/s10792-015-0151-x. Epub 2015 Nov 14.


Intravitreal AAV2.COMP-Ang1 Prevents Neurovascular Degeneration in a Murine Model of Diabetic Retinopathy.

Cahoon JM, Rai RR, Carroll LS, Uehara H, Zhang X, O'Neil CL, Medina RJ, Das SK, Muddana SK, Olson PR, Nielson S, Walker K, Flood MM, Messenger WB, Archer BJ, Barabas P, Krizaj D, Gibson CC, Li DY, Koh GY, Gao G, Stitt AW, Ambati BK.

Diabetes. 2015 Dec;64(12):4247-59. doi: 10.2337/db14-1030. Epub 2015 Sep 4.


Comparison of the Anti-angiogenic and Anti-inflammatory Effects of Two Antibiotics: Clarithromycin Versus Moxifloxacin.

Uehara H, Das SK, Cho YK, Archer B, Ambati BK.

Curr Eye Res. 2016 Apr;41(4):474-84. doi: 10.3109/02713683.2015.1037926. Epub 2015 Jun 30.


Correlation of in vivo and in vitro methods in measuring choroidal vascularization volumes using a subretinal injection induced choroidal neovascularization model.

Nie C, Zhang MN, Zhao HW, Olsen TD, Jackman K, Hu LN, Ma WP, Chen XF, Wang J, Zhang Y, Gao TS, Uehara H, Ambati BK, Luo L.

Chin Med J (Engl). 2015 Jun 5;128(11):1516-22. doi: 10.4103/0366-6999.157681.


Neurodegeneration severity can be predicted from early microglia alterations monitored in vivo in a mouse model of chronic glaucoma.

Bosco A, Romero CO, Breen KT, Chagovetz AA, Steele MR, Ambati BK, Vetter ML.

Dis Model Mech. 2015 May;8(5):443-55. doi: 10.1242/dmm.018788. Epub 2015 Mar 9.


Voice disorders in Sjögren's syndrome: Prevalence and related risk factors.

Pierce JL, Tanner K, Merrill RM, Miller KL, Ambati BK, Kendall KA, Roy N.

Laryngoscope. 2015 Jun;125(6):1385-92. doi: 10.1002/lary.25112. Epub 2014 Dec 27.


In vivo ZW800-microbead imaging of retinal and choroidal vascular leakage in mice.

Gupta I, Cahoon J, Zhang X, Jones AD, Ahmed F, Uehara H, Messenger W, Ambati BK.

Exp Eye Res. 2015 May;134:155-8. doi: 10.1016/j.exer.2014.12.013. Epub 2014 Dec 20.


Morpholino-Mediated Isoform Modulation of Vascular Endothelial Growth Factor Receptor-2 (VEGFR2) Reduces Colon Cancer Xenograft Growth.

Stagg BC, Uehara H, Lambert N, Rai R, Gupta I, Radmall B, Bates T, Ambati BK.

Cancers (Basel). 2014 Nov 26;6(4):2330-42. doi: 10.3390/cancers6042330.


Trimanual Anterior Vitrectomy: A Novel Technique to Manage Vitreous Loss during Phacoemulsification.

Taggart MG, Morshedi RG, Ambati BK.

Case Rep Ophthalmol. 2014 Nov 15;5(3):373-9. doi: 10.1159/000369272. eCollection 2014 Sep.


IL-18 is not therapeutic for neovascular age-related macular degeneration.

Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V, Yasuma R, Kim Y, Bastos-Carvalho A, Kerur N, Gelfand BD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Nagai H, Haro I, Núñez G, Ambati BK, Hinton DR, Ambati J.

Nat Med. 2014 Dec;20(12):1372-5. doi: 10.1038/nm.3671. No abstract available.


DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.

Kim Y, Tarallo V, Kerur N, Yasuma T, Gelfand BD, Bastos-Carvalho A, Hirano Y, Yasuma R, Mizutani T, Fowler BJ, Li S, Kaneko H, Bogdanovich S, Ambati BK, Hinton DR, Hauswirth WW, Hakem R, Wright C, Ambati J.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16082-7. doi: 10.1073/pnas.1403814111. Epub 2014 Oct 27.


Endometrial VEGF induces placental sFLT1 and leads to pregnancy complications.

Fan X, Rai A, Kambham N, Sung JF, Singh N, Petitt M, Dhal S, Agrawal R, Sutton RE, Druzin ML, Gambhir SS, Ambati BK, Cross JC, Nayak NR.

J Clin Invest. 2014 Nov;124(11):4941-52. doi: 10.1172/JCI76864. Epub 2014 Oct 20.


AAV2 delivery of Flt23k intraceptors inhibits murine choroidal neovascularization.

Zhang X, Das SK, Passi SF, Uehara H, Bohner A, Chen M, Tiem M, Archer B, Ambati BK.

Mol Ther. 2015 Feb;23(2):226-34. doi: 10.1038/mt.2014.199. Epub 2014 Oct 13.


The reduction of serum soluble Flt-1 in patients with neovascular age-related macular degeneration.

Uehara H, Mamalis C, McFadden M, Taggart M, Stagg B, Passi S, Earle P, Chakravarthy U, Hogg RE, Ambati BK.

Am J Ophthalmol. 2015 Jan;159(1):92-100.e1-2. doi: 10.1016/j.ajo.2014.09.036. Epub 2014 Oct 18.


Gender-based salary disparities: it pays to take a closer look.

Ambati BK.

Acad Med. 2014 Aug;89(8):1094. doi: 10.1097/ACM.0000000000000379. No abstract available.


Spectacle Independence after Cataract Extraction in Post-Radial Keratotomy Patients Using Hybrid Monovision with ReSTOR(®) Multifocal and TECNIS(®) Monofocal Intraocular Lenses.

Gupta I, Oakey Z, Ahmed F, Ambati BK.

Case Rep Ophthalmol. 2014 May 22;5(2):157-61. doi: 10.1159/000363372. eCollection 2014 May.


Pharmacokinetics and efficacy of Bioerodible Dexamethasone implant in Concanavalin A-induced uveitic cataract rabbit model.

Chennamaneni SR, Bohner A, Bernhisel A, Ambati BK.

Pharm Res. 2014 Nov;31(11):3179-90. doi: 10.1007/s11095-014-1410-7. Epub 2014 Jun 20.


Vimentin knockdown decreases corneal opacity.

Das SK, Gupta I, Cho YK, Zhang X, Uehara H, Muddana SK, Bernhisel AA, Archer B, Ambati BK.

Invest Ophthalmol Vis Sci. 2014 May 22;55(7):4030-40. doi: 10.1167/iovs.13-13494.


Angiographic features of transgenic mice with increased expression of human serine protease HTRA1 in retinal pigment epithelium.

Kumar S, Berriochoa Z, Ambati BK, Fu Y.

Invest Ophthalmol Vis Sci. 2014 May 22;55(6):3842-50. doi: 10.1167/iovs.13-13111.


FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression.

Owen LA, Morrison MA, Ahn J, Woo SJ, Sato H, Robinson R, Morgan DJ, Zacharaki F, Simeonova M, Uehara H, Chakravarthy U, Hogg RE, Ambati BK, Kotoula M, Baehr W, Haider NB, Silvestri G, Miller JW, Tsironi EE, Farrer LA, Kim IK, Park KH, DeAngelis MM.

Invest Ophthalmol Vis Sci. 2014 May 8;55(6):3543-54. doi: 10.1167/iovs.14-14047.


Dry eye predisposes to corneal neovascularization and lymphangiogenesis after corneal injury in a murine model.

Cho YK, Archer B, Ambati BK.

Cornea. 2014 Jun;33(6):621-7. doi: 10.1097/ICO.0000000000000107.


Rejuvenating clinician-scientist training.

Ambati BK, Cahoon J.

Invest Ophthalmol Vis Sci. 2014 Mar 28;55(3):1853-5. doi: 10.1167/iovs.14-14167. Review.


TGFβ and PDGF-B signaling blockade inhibits myofibroblast development from both bone marrow-derived and keratocyte-derived precursor cells in vivo.

Singh V, Jaini R, Torricelli AA, Santhiago MR, Singh N, Ambati BK, Wilson SE.

Exp Eye Res. 2014 Apr;121:35-40. doi: 10.1016/j.exer.2014.02.013. Epub 2014 Feb 26.


Acridine orange leukocyte fluorography in mice.

Cahoon JM, Olson PR, Nielson S, Miya TR, Bankhead P, McGeown JG, Curtis TM, Ambati BK.

Exp Eye Res. 2014 Mar;120:15-9. doi: 10.1016/j.exer.2013.12.002. Epub 2013 Dec 12.


Presurgical corticosteroid treatment improves corneal transplant survival in mice.

Kim HK, Choi JA, Uehara H, Zhang X, Ambati BK, Cho YK.

Cornea. 2013 Dec;32(12):1591-1598. doi: 10.1097/ICO.0b013e31829ebb0d.


Minus Piggyback Lens Overlaying ReSTOR(®) Multifocal Lens in High Myopia.

Gupta I, Oakey Z, Stagg BC, Ambati BK.

Case Rep Ophthalmol. 2013 Jun 28;4(2):57-60. doi: 10.1159/000353497. Print 2013 May.


Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1.

Luo L, Uehara H, Zhang X, Das SK, Olsen T, Holt D, Simonis JM, Jackman K, Singh N, Miya TR, Huang W, Ahmed F, Bastos-Carvalho A, Le YZ, Mamalis C, Chiodo VA, Hauswirth WW, Baffi J, Lacal PM, Orecchia A, Ferrara N, Gao G, Young-Hee K, Fu Y, Owen L, Albuquerque R, Baehr W, Thomas K, Li DY, Chalam KV, Shibuya M, Grisanti S, Wilson DJ, Ambati J, Ambati BK.

Elife. 2013 Jun 18;2:e00324. doi: 10.7554/eLife.00324.


Soluble vascular endothelial growth factor receptor 3 is essential for corneal alymphaticity.

Singh N, Tiem M, Watkins R, Cho YK, Wang Y, Olsen T, Uehara H, Mamalis C, Luo L, Oakey Z, Ambati BK.

Blood. 2013 May 16;121(20):4242-9. doi: 10.1182/blood-2012-08-453043. Epub 2013 Mar 8.


Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration.

Luo L, Zhang X, Hirano Y, Tyagi P, Barabás P, Uehara H, Miya TR, Singh N, Archer B, Qazi Y, Jackman K, Das SK, Olsen T, Chennamaneni SR, Stagg BC, Ahmed F, Emerson L, Zygmunt K, Whitaker R, Mamalis C, Huang W, Gao G, Srinivas SP, Krizaj D, Baffi J, Ambati J, Kompella UB, Ambati BK.

ACS Nano. 2013 Apr 23;7(4):3264-75. doi: 10.1021/nn305958y. Epub 2013 Mar 20.

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