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Items: 1 to 50 of 93

1.

MYC in Germinal Center-derived lymphomas: Mechanisms and therapeutic opportunities.

Bisso A, Sabò A, Amati B.

Immunol Rev. 2019 Mar;288(1):178-197. doi: 10.1111/imr.12734. Review.

PMID:
30874346
2.

p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value.

Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D'Elia E, Aobuli X, Pasi CE, Reavie L, Bonetti P, Punzi S, Casoli L, Sabò A, Moroni MC, Dellino GI, Amati B, Nicassio F, Lanfrancone L, Pelicci PG.

Cell Rep. 2019 Jan 15;26(3):624-638.e8. doi: 10.1016/j.celrep.2018.12.071.

3.

Catalogue of the primary types of marine molluscan taxa described by Tommaso Allery Di Maria, Marquis of Monterosato, deposited in the Museo Civico di Zoologia, Roma.

Appolloni M, Smriglio C, Amati B, LugliÈ L, Nofroni I, Tringali LP, Mariottini P, Oliverio M.

Zootaxa. 2018 Sep 14;4477(1):1-138. doi: 10.11646/zootaxa.4477.1.1.

PMID:
30313335
4.

BRD4 and MYC-clarifying regulatory specificity.

Sabò A, Amati B.

Science. 2018 May 18;360(6390):713-714. doi: 10.1126/science.aat6664. No abstract available.

PMID:
29773735
5.

YAP and TAZ are dispensable for physiological and malignant haematopoiesis.

Donato E, Biagioni F, Bisso A, Caganova M, Amati B, Campaner S.

Leukemia. 2018 Sep;32(9):2037-2040. doi: 10.1038/s41375-018-0111-3. Epub 2018 Mar 26. No abstract available.

6.

Therapeutic synergy between tigecycline and venetoclax in a preclinical model of MYC/BCL2 double-hit B cell lymphoma.

Ravà M, D'Andrea A, Nicoli P, Gritti I, Donati G, Doni M, Giorgio M, Olivero D, Amati B.

Sci Transl Med. 2018 Jan 31;10(426). pii: eaan8723. doi: 10.1126/scitranslmed.aan8723.

PMID:
29386360
7.

Transcriptional integration of mitogenic and mechanical signals by Myc and YAP.

Croci O, De Fazio S, Biagioni F, Donato E, Caganova M, Curti L, Doni M, Sberna S, Aldeghi D, Biancotto C, Verrecchia A, Olivero D, Amati B, Campaner S.

Genes Dev. 2017 Oct 15;31(20):2017-2022. doi: 10.1101/gad.301184.117. Epub 2017 Nov 15.

8.

Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation.

de Pretis S, Kress TR, Morelli MJ, Sabò A, Locarno C, Verrecchia A, Doni M, Campaner S, Amati B, Pelizzola M.

Genome Res. 2017 Oct;27(10):1658-1664. doi: 10.1101/gr.226035.117. Epub 2017 Sep 13.

9.

FunChIP: an R/Bioconductor package for functional classification of ChIP-seq shapes.

Parodi ACL, Sangalli LM, Vantini S, Amati B, Secchi P, Morelli MJ.

Bioinformatics. 2017 Aug 15;33(16):2570-2572. doi: 10.1093/bioinformatics/btx201.

PMID:
28398543
10.

Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk.

Piccolo V, Curina A, Genua M, Ghisletti S, Simonatto M, Sabò A, Amati B, Ostuni R, Natoli G.

Nat Immunol. 2017 May;18(5):530-540. doi: 10.1038/ni.3710. Epub 2017 Mar 13.

11.

Genome-wide analysis of p53-regulated transcription in Myc-driven lymphomas.

Tonelli C, Morelli MJ, Sabò A, Verrecchia A, Rotta L, Capra T, Bianchi S, Campaner S, Amati B.

Oncogene. 2017 May 25;36(21):2921-2929. doi: 10.1038/onc.2016.443. Epub 2017 Jan 16.

12.

X-box Binding Protein 1 Regulates Unfolded Protein, Acute-Phase, and DNA Damage Responses During Regeneration of Mouse Liver.

Argemí J, Kress TR, Chang HCY, Ferrero R, Bértolo C, Moreno H, González-Aparicio M, Uriarte I, Guembe L, Segura V, Hernández-Alcoceba R, Ávila MA, Amati B, Prieto J, Aragón T.

Gastroenterology. 2017 Apr;152(5):1203-1216.e15. doi: 10.1053/j.gastro.2016.12.040. Epub 2017 Jan 9.

PMID:
28082079
13.

Mutual epithelium-macrophage dependency in liver carcinogenesis mediated by ST18.

Ravà M, D'Andrea A, Doni M, Kress TR, Ostuni R, Bianchi V, Morelli MJ, Collino A, Ghisletti S, Nicoli P, Recordati C, Iascone M, Sonzogni A, D'Antiga L, Shukla R, Faulkner GJ, Natoli G, Campaner S, Amati B.

Hepatology. 2017 May;65(5):1708-1719. doi: 10.1002/hep.28942. Epub 2016 Dec 30.

14.

Smyd2 is a Myc-regulated gene critical for MLL-AF9 induced leukemogenesis.

Bagislar S, Sabò A, Kress TR, Doni M, Nicoli P, Campaner S, Amati B.

Oncotarget. 2016 Oct 11;7(41):66398-66415. doi: 10.18632/oncotarget.12012.

15.

The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas.

D'Andrea A, Gritti I, Nicoli P, Giorgio M, Doni M, Conti A, Bianchi V, Casoli L, Sabò A, Mironov A, Beznoussenko GV, Amati B.

Oncotarget. 2016 Nov 8;7(45):72415-72430. doi: 10.18632/oncotarget.11719.

16.

Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.

Walerych D, Lisek K, Sommaggio R, Piazza S, Ciani Y, Dalla E, Rajkowska K, Gaweda-Walerych K, Ingallina E, Tonelli C, Morelli MJ, Amato A, Eterno V, Zambelli A, Rosato A, Amati B, Wiśniewski JR, Del Sal G.

Nat Cell Biol. 2016 Aug;18(8):897-909. doi: 10.1038/ncb3380. Epub 2016 Jun 27.

PMID:
27347849
17.

Integrated Systems for NGS Data Management and Analysis: Open Issues and Available Solutions.

Bianchi V, Ceol A, Ogier AG, de Pretis S, Galeota E, Kishore K, Bora P, Croci O, Campaner S, Amati B, Morelli MJ, Pelizzola M.

Front Genet. 2016 May 6;7:75. doi: 10.3389/fgene.2016.00075. eCollection 2016.

18.

Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors.

Kress TR, Pellanda P, Pellegrinet L, Bianchi V, Nicoli P, Doni M, Recordati C, Bianchi S, Rotta L, Capra T, Ravà M, Verrecchia A, Radaelli E, Littlewood TD, Evan GI, Amati B.

Cancer Res. 2016 Jun 15;76(12):3463-72. doi: 10.1158/0008-5472.CAN-16-0316. Epub 2016 Apr 13.

19.

p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivo: Computational analysis of next-generation sequencing data.

Tonelli C, Amati B, Morelli MJ.

Genom Data. 2015 Nov 7;7:29-31. doi: 10.1016/j.gdata.2015.11.006. eCollection 2016 Mar.

20.

Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc.

D'Artista L, Bisso A, Piontini A, Doni M, Verrecchia A, Kress TR, Morelli MJ, Del Sal G, Amati B, Campaner S.

Oncotarget. 2016 Apr 19;7(16):21786-98. doi: 10.18632/oncotarget.7846.

21.

Degradation dynamics of microRNAs revealed by a novel pulse-chase approach.

Marzi MJ, Ghini F, Cerruti B, de Pretis S, Bonetti P, Giacomelli C, Gorski MM, Kress T, Pelizzola M, Muller H, Amati B, Nicassio F.

Genome Res. 2016 Apr;26(4):554-65. doi: 10.1101/gr.198788.115. Epub 2016 Jan 28.

22.

methylPipe and compEpiTools: a suite of R packages for the integrative analysis of epigenomics data.

Kishore K, de Pretis S, Lister R, Morelli MJ, Bianchi V, Amati B, Ecker JR, Pelizzola M.

BMC Bioinformatics. 2015 Sep 29;16:313. doi: 10.1186/s12859-015-0742-6.

23.

MYC: connecting selective transcriptional control to global RNA production.

Kress TR, Sabò A, Amati B.

Nat Rev Cancer. 2015 Oct;15(10):593-607. doi: 10.1038/nrc3984. Epub 2015 Sep 18. Review.

PMID:
26383138
24.

Genome-wide analysis of p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivo.

Tonelli C, Morelli MJ, Bianchi S, Rotta L, Capra T, Sabò A, Campaner S, Amati B.

Oncotarget. 2015 Sep 22;6(28):24611-26. doi: 10.18632/oncotarget.5232.

25.

Selective transcriptional regulation by Myc: Experimental design and computational analysis of high-throughput sequencing data.

Pelizzola M, Morelli MJ, Sabò A, Kress TR, de Pretis S, Amati B.

Data Brief. 2015 Feb 12;3:40-6. doi: 10.1016/j.dib.2015.02.003. eCollection 2015 Jun.

26.

MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis.

Koh CM, Bezzi M, Low DH, Ang WX, Teo SX, Gay FP, Al-Haddawi M, Tan SY, Osato M, Sabò A, Amati B, Wee KB, Guccione E.

Nature. 2015 Jul 2;523(7558):96-100. doi: 10.1038/nature14351. Epub 2015 May 11.

PMID:
25970242
27.

INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments.

de Pretis S, Kress T, Morelli MJ, Melloni GE, Riva L, Amati B, Pelizzola M.

Bioinformatics. 2015 Sep 1;31(17):2829-35. doi: 10.1093/bioinformatics/btv288. Epub 2015 May 7.

PMID:
25957348
28.

Revision of the Recent Mediterranean species of Mitromorpha Carpenter, 1865 (Gastropoda, Conoidea, Mitromorphidae) with the description of seven new species.

Amati B, Smriglio C, Oliverio M.

Zootaxa. 2015 Mar 12;3931(2):151-95. doi: 10.11646/zootaxa.3931.2.1.

PMID:
25781821
29.

Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.

Sabò A, Kress TR, Pelizzola M, de Pretis S, Gorski MM, Tesi A, Morelli MJ, Bora P, Doni M, Verrecchia A, Tonelli C, Fagà G, Bianchi V, Ronchi A, Low D, Müller H, Guccione E, Campaner S, Amati B.

Nature. 2014 Jul 24;511(7510):488-492. doi: 10.1038/nature13537. Epub 2014 Jul 9.

30.

Relationship between genome and epigenome--challenges and requirements for future research.

Almouzni G, Altucci L, Amati B, Ashley N, Baulcombe D, Beaujean N, Bock C, Bongcam-Rudloff E, Bousquet J, Braun S, Bressac-de Paillerets B, Bussemakers M, Clarke L, Conesa A, Estivill X, Fazeli A, Grgurević N, Gut I, Heijmans BT, Hermouet S, Houwing-Duistermaat J, Iacobucci I, Ilaš J, Kandimalla R, Krauss-Etschmann S, Lasko P, Lehmann S, Lindroth A, Majdič G, Marcotte E, Martinelli G, Martinet N, Meyer E, Miceli C, Mills K, Moreno-Villanueva M, Morvan G, Nickel D, Niesler B, Nowacki M, Nowak J, Ossowski S, Pelizzola M, Pochet R, Potočnik U, Radwanska M, Raes J, Rattray M, Robinson MD, Roelen B, Sauer S, Schinzer D, Slagboom E, Spector T, Stunnenberg HG, Tiligada E, Torres-Padilla ME, Tsonaka R, Van Soom A, Vidaković M, Widschwendter M.

BMC Genomics. 2014 Jun 18;15:487. doi: 10.1186/1471-2164-15-487.

31.

SUMOylation of Myc-family proteins.

Sabò A, Doni M, Amati B.

PLoS One. 2014 Mar 7;9(3):e91072. doi: 10.1371/journal.pone.0091072. eCollection 2014.

32.

Genome recognition by MYC.

Sabò A, Amati B.

Cold Spring Harb Perspect Med. 2014 Feb 1;4(2). pii: a014191. doi: 10.1101/cshperspect.a014191. Review.

33.

A non-redundant function of cyclin E1 in hematopoietic stem cells.

Campaner S, Viale A, De Fazio S, Doni M, De Franco F, D'Artista L, Sardella D, Pelicci PG, Amati B.

Cell Cycle. 2013 Dec 1;12(23):3663-72. doi: 10.4161/cc.26584. Epub 2013 Sep 25.

34.

Dual regulation of Myc by Abl.

Sanchez-Arévalo Lobo VJ, Doni M, Verrecchia A, Sanulli S, Fagà G, Piontini A, Bianchi M, Conacci-Sorrell M, Mazzarol G, Peg V, Losa JH, Ronchi P, Ponzoni M, Eisenman RN, Doglioni C, Amati B.

Oncogene. 2013 Nov 7;32(45):5261-71. doi: 10.1038/onc.2012.621. Epub 2013 Jan 14.

35.

Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance.

Campaner S, Amati B.

Cell Div. 2012 Feb 28;7(1):6. doi: 10.1186/1747-1028-7-6.

36.

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance.

Migliori V, Müller J, Phalke S, Low D, Bezzi M, Mok WC, Sahu SK, Gunaratne J, Capasso P, Bassi C, Cecatiello V, De Marco A, Blackstock W, Kuznetsov V, Amati B, Mapelli M, Guccione E.

Nat Struct Mol Biol. 2012 Jan 8;19(2):136-44. doi: 10.1038/nsmb.2209.

PMID:
22231400
37.

Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors.

Murga M, Campaner S, Lopez-Contreras AJ, Toledo LI, Soria R, Montaña MF, Artista L, Schleker T, Guerra C, Garcia E, Barbacid M, Hidalgo M, Amati B, Fernandez-Capetillo O.

Nat Struct Mol Biol. 2011 Nov 27;18(12):1331-1335. doi: 10.1038/nsmb.2189.

38.

Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts.

Perna D, Fagà G, Verrecchia A, Gorski MM, Barozzi I, Narang V, Khng J, Lim KC, Sung WK, Sanges R, Stupka E, Oskarsson T, Trumpp A, Wei CL, Müller H, Amati B.

Oncogene. 2012 Mar 29;31(13):1695-709. doi: 10.1038/onc.2011.359. Epub 2011 Aug 22.

39.

The methyltransferase Set7/9 (Setd7) is dispensable for the p53-mediated DNA damage response in vivo.

Campaner S, Spreafico F, Burgold T, Doni M, Rosato U, Amati B, Testa G.

Mol Cell. 2011 Aug 19;43(4):681-8. doi: 10.1016/j.molcel.2011.08.007.

40.

Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth.

Miluzio A, Beugnet A, Grosso S, Brina D, Mancino M, Campaner S, Amati B, de Marco A, Biffo S.

Cancer Cell. 2011 Jun 14;19(6):765-75. doi: 10.1016/j.ccr.2011.04.018.

41.

TGFβ-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas.

Müller J, Samans B, van Riggelen J, Fagà G, Peh K N R, Wei CL, Müller H, Amati B, Felsher D, Eilers M.

Cell Cycle. 2010 Dec 1;9(23):4622-6.

PMID:
21127397
42.

Myc, Cdk2 and cellular senescence: Old players, new game.

Campaner S, Doni M, Verrecchia A, Fagà G, Bianchi L, Amati B.

Cell Cycle. 2010 Sep 15;9(18):3655-61. Epub 2010 Sep 15.

PMID:
20818171
43.

Chromatin association and regulation of rDNA transcription by the Ras-family protein RasL11a.

Pistoni M, Verrecchia A, Doni M, Guccione E, Amati B.

EMBO J. 2010 Apr 7;29(7):1215-24. doi: 10.1038/emboj.2010.16. Epub 2010 Feb 18.

44.

Cdk2 suppresses cellular senescence induced by the c-myc oncogene.

Campaner S, Doni M, Hydbring P, Verrecchia A, Bianchi L, Sardella D, Schleker T, Perna D, Tronnersjö S, Murga M, Fernandez-Capetillo O, Barbacid M, Larsson LG, Amati B.

Nat Cell Biol. 2010 Jan;12(1):54-9; sup pp 1-14. doi: 10.1038/ncb2004. Epub 2009 Dec 13.

PMID:
20010815
45.

Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks.

Bua DJ, Kuo AJ, Cheung P, Liu CL, Migliori V, Espejo A, Casadio F, Bassi C, Amati B, Bedford MT, Guccione E, Gozani O.

PLoS One. 2009 Aug 26;4(8):e6789. doi: 10.1371/journal.pone.0006789.

46.

Analysis of Myc-induced histone modifications on target chromatin.

Martinato F, Cesaroni M, Amati B, Guccione E.

PLoS One. 2008;3(11):e3650. doi: 10.1371/journal.pone.0003650. Epub 2008 Nov 5.

47.

A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition.

Smith AP, Verrecchia A, Fagà G, Doni M, Perna D, Martinato F, Guccione E, Amati B.

Oncogene. 2009 Jan 22;28(3):422-30. doi: 10.1038/onc.2008.395. Epub 2008 Nov 3.

PMID:
18978814
48.

Immortalization of human neural stem cells with the c-myc mutant T58A.

De Filippis L, Ferrari D, Rota Nodari L, Amati B, Snyder E, Vescovi AL.

PLoS One. 2008 Oct 2;3(10):e3310. doi: 10.1371/journal.pone.0003310.

49.

Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma.

Bonetti P, Davoli T, Sironi C, Amati B, Pelicci PG, Colombo E.

J Cell Biol. 2008 Jul 14;182(1):19-26. doi: 10.1083/jcb.200711040.

50.

Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.

Guccione E, Bassi C, Casadio F, Martinato F, Cesaroni M, Schuchlautz H, Lüscher B, Amati B.

Nature. 2007 Oct 18;449(7164):933-7. Epub 2007 Sep 26.

PMID:
17898714

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