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Items: 18


Mesenchymal COX2-PG secretome engages NR4A-WNT signalling axis in haematopoietic progenitors to suppress anti-leukaemia immunity.

Wu L, Amarachintha S, Xu J, Oley F Jr, Du W.

Br J Haematol. 2018 Nov;183(3):445-456. doi: 10.1111/bjh.15548. Epub 2018 Aug 14.


Enhanced survival following oral and systemic Salmonella enterica serovar Typhimurium infection in polymeric immunoglobulin receptor knockout mice.

Betz KJ, Maier EA, Amarachintha S, Wu D, Karmele EP, Kinder JM, Steinbrecher KA, McNeal MM, Luzader DH, Hogan SP, Moore SR.

PLoS One. 2018 Jun 1;13(6):e0198434. doi: 10.1371/journal.pone.0198434. eCollection 2018.


Guanylate cyclase C reduces invasion of intestinal epithelial cells by bacterial pathogens.

Amarachintha S, Harmel-Laws E, Steinbrecher KA.

Sci Rep. 2018 Jan 24;8(1):1521. doi: 10.1038/s41598-018-19868-z.


Persistent response of Fanconi anemia haematopoietic stem and progenitor cells to oxidative stress.

Li Y, Amarachintha S, Wilson AF, Li X, Du W.

Cell Cycle. 2017 Jun 18;16(12):1201-1209. doi: 10.1080/15384101.2017.1320627. Epub 2017 May 5.


In Vivo RNAi Screen Unveils PPARγ as a Regulator of Hematopoietic Stem Cell Homeostasis.

Sertorio M, Du W, Amarachintha S, Wilson A, Pang Q.

Stem Cell Reports. 2017 May 9;8(5):1242-1255. doi: 10.1016/j.stemcr.2017.03.008. Epub 2017 Apr 13.


Activation of TGF-β activated kinase 1 promotes colon mucosal pathogenesis in inflammatory bowel disease.

Liu Z, Kong F, Vallance JE, Harmel-Laws E, Amarachintha S, Steinbrecher KA, Rosen MJ, Bhattacharyya S.

Physiol Rep. 2017 Apr;5(7). pii: e13181. doi: 10.14814/phy2.13181.


The immune receptor Trem1 cooperates with diminished DNA damage response to induce preleukemic stem cell expansion.

Du W, Amarachintha S, Wilson A, Pang Q.

Leukemia. 2017 Feb;31(2):423-433. doi: 10.1038/leu.2016.242. Epub 2016 Aug 29.


The Fanconi anemia pathway controls oncogenic response in hematopoietic stem and progenitor cells by regulating PRMT5-mediated p53 arginine methylation.

Du W, Amarachintha S, Erden O, Wilson A, Pang Q.

Oncotarget. 2016 Sep 13;7(37):60005-60020. doi: 10.18632/oncotarget.11088.


Loss of Fancc Impairs Antibody-Secreting Cell Differentiation in Mice through Deregulating the Wnt Signaling Pathway.

Sertorio M, Amarachintha S, Wilson A, Pang Q.

J Immunol. 2016 Apr 1;196(7):2986-94. doi: 10.4049/jimmunol.1501056. Epub 2016 Feb 19.


SCO2 Mediates Oxidative Stress-Induced Glycolysis to Oxidative Phosphorylation Switch in Hematopoietic Stem Cells.

Du W, Amarachintha S, Wilson AF, Pang Q.

Stem Cells. 2016 Apr;34(4):960-71. doi: 10.1002/stem.2260. Epub 2015 Dec 31.


Fancb deficiency impairs hematopoietic stem cell function.

Du W, Amarachintha S, Erden O, Wilson A, Meetei AR, Andreassen PR, Namekawa SH, Pang Q.

Sci Rep. 2015 Dec 11;5:18127. doi: 10.1038/srep18127.


Fanconi Anemia Mesenchymal Stromal Cells-Derived Glycerophospholipids Skew Hematopoietic Stem Cell Differentiation Through Toll-Like Receptor Signaling.

Amarachintha S, Sertorio M, Wilson A, Li X, Pang Q.

Stem Cells. 2015 Nov;33(11):3382-96. doi: 10.1002/stem.2100. Epub 2015 Jul 24.


Transcriptional profiling of Foxo3a and Fancd2 regulated genes in mouse hematopoietic stem cells.

Li X, Zhang T, Wilson A, Amarachintha S, Sertorio M, Pang Q.

Genom Data. 2015 Jun 1;4:148-149.


Effect of Cdc42 domains on filopodia sensing, cell orientation, and haptotaxis.

Amarachintha SP, Ryan KJ, Cayer M, Boudreau NS, Johnson NM, Heckman CA.

Cell Signal. 2015 Mar;27(3):683-93. doi: 10.1016/j.cellsig.2014.11.025. Epub 2014 Nov 28.


Inflammation-mediated notch signaling skews fanconi anemia hematopoietic stem cell differentiation.

Du W, Amarachintha S, Sipple J, Schick J, Steinbrecher K, Pang Q.

J Immunol. 2013 Sep 1;191(5):2806-17. doi: 10.4049/jimmunol.1203474. Epub 2013 Aug 7.


mTOR kinase inhibitor sensitizes T-cell lymphoblastic leukemia for chemotherapy-induced DNA damage via suppressing FANCD2 expression.

Guo F, Li J, Zhang S, Du W, Amarachintha S, Sipple J, Phelan J, Grimes HL, Zheng Y, Pang Q.

Leukemia. 2014 Jan;28(1):203-6. doi: 10.1038/leu.2013.215. Epub 2013 Jul 15. No abstract available.


Evolution of genomic sequence inhomogeneity at mid-range scales.

Prakash A, Shepard SS, He J, Hart B, Chen M, Amarachintha SP, Mileyeva-Biebesheimer O, Bechtel J, Fedorov A.

BMC Genomics. 2009 Nov 5;10:513. doi: 10.1186/1471-2164-10-513.

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