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Items: 1 to 50 of 127

1.

Effect of Calcium Carbonate Encapsulation on the Activity of Orally Administered CpG Oligonucleotides.

Kayraklioglu N, Scheiermann J, Alvord WG, Klinman DM.

Mol Ther Nucleic Acids. 2017 Sep 15;8:243-249. doi: 10.1016/j.omtn.2017.06.015. Epub 2017 Jun 23.

2.

Quantitative imaging for development of companion diagnostics to drugs targeting HGF/MET.

Huang F, Ma Z, Pollan S, Yuan X, Swartwood S, Gertych A, Rodriguez M, Mallick J, Bhele S, Guindi M, Dhall D, Walts AE, Bose S, de Peralta Venturina M, Marchevsky AM, Luthringer DJ, Feller SM, Berman B, Freeman MR, Alvord WG, Vande Woude G, Amin MB, Knudsen BS.

J Pathol Clin Res. 2016 Jul 1;2(4):210-222. eCollection 2016 Oct.

3.

Adoptive Transfer of Engineered Rhesus Simian Immunodeficiency Virus-Specific CD8+ T Cells Reduces the Number of Transmitted/Founder Viruses Established in Rhesus Macaques.

Ayala VI, Trivett MT, Barsov EV, Jain S, Piatak M Jr, Trubey CM, Alvord WG, Chertova E, Roser JD, Smedley J, Komin A, Keele BF, Ohlen C, Ott DE.

J Virol. 2016 Oct 14;90(21):9942-9952. Print 2016 Nov 1.

4.

Impact of early cART in the gut during acute HIV infection.

Deleage C, Schuetz A, Alvord WG, Johnston L, Hao XP, Morcock DR, Rerknimitr R, Fletcher JL, Puttamaswin S, Phanuphak N, Dewar R, McCune JM, Sereti I, Robb M, Kim JH, Schacker TW, Hunt P, Lifson JD, Ananworanich J, Estes JD.

JCI Insight. 2016 Jul 7;1(10). pii: e87065.

5.

APOBEC3 proteins can copackage and comutate HIV-1 genomes.

Desimmie BA, Burdick RC, Izumi T, Doi H, Shao W, Alvord WG, Sato K, Koyanagi Y, Jones S, Wilson E, Hill S, Maldarelli F, Hu WS, Pathak VK.

Nucleic Acids Res. 2016 Sep 19;44(16):7848-65. doi: 10.1093/nar/gkw653. Epub 2016 Jul 20.

6.

Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy.

Del Prete GQ, Oswald K, Lara A, Shoemaker R, Smedley J, Macallister R, Coalter V, Wiles A, Wiles R, Li Y, Fast R, Kiser R, Lu B, Zheng J, Alvord WG, Trubey CM, Piatak M Jr, Deleage C, Keele BF, Estes JD, Hesselgesser J, Geleziunas R, Lifson JD.

Antimicrob Agents Chemother. 2015 Dec 28;60(3):1560-72. doi: 10.1128/AAC.02625-15.

7.

Co-regulation of mitochondrial respiration by proline dehydrogenase/oxidase and succinate.

Hancock CN, Liu W, Alvord WG, Phang JM.

Amino Acids. 2016 Mar;48(3):859-872. doi: 10.1007/s00726-015-2134-7. Epub 2015 Dec 10. Erratum in: Amino Acids. 2016 May;48(5):1337-8.

8.

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection.

Hao XP, Lucero CM, Turkbey B, Bernardo ML, Morcock DR, Deleage C, Trubey CM, Smedley J, Klatt NR, Giavedoni LD, Kristoff J, Xu A, Del Prete GQ, Keele BF, Rao SS, Alvord WG, Choyke PL, Lifson JD, Brenchley JM, Apetrei C, Pandrea I, Estes JD.

Nat Commun. 2015 Aug 18;6:8020. doi: 10.1038/ncomms9020.

9.

High recombination potential of subtype A HIV-1.

Nikolaitchik O, Keele B, Gorelick R, Alvord WG, Mazurov D, Pathak VK, Hu WS.

Virology. 2015 Oct;484:334-40. doi: 10.1016/j.virol.2015.06.025. Epub 2015 Jul 9.

10.

Serum-based tracking of de novo initiated liver cancer progression reveals early immunoregulation and response to therapy.

Subleski JJ, Scarzello AJ, Alvord WG, Jiang Q, Stauffer JK, Kronfli A, Saleh B, Back T, Weiss JM, Wiltrout RH.

J Hepatol. 2015 Nov;63(5):1181-9. doi: 10.1016/j.jhep.2015.06.021. Epub 2015 Jul 2.

11.

Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques.

Del Prete GQ, Shoemaker R, Oswald K, Lara A, Trubey CM, Fast R, Schneider DK, Kiser R, Coalter V, Wiles A, Wiles R, Freemire B, Keele BF, Estes JD, Quiñones OA, Smedley J, Macallister R, Sanchez RI, Wai JS, Tan CM, Alvord WG, Hazuda DJ, Piatak M Jr, Lifson JD.

Antimicrob Agents Chemother. 2014 Nov;58(11):6790-806. doi: 10.1128/AAC.03746-14. Epub 2014 Sep 2.

12.

Molecularly tagged simian immunodeficiency virus SIVmac239 synthetic swarm for tracking independent infection events.

Del Prete GQ, Park H, Fennessey CM, Reid C, Lipkey L, Newman L, Oswald K, Kahl C, Piatak M Jr, Quiñones OA, Alvord WG, Smedley J, Estes JD, Lifson JD, Picker LJ, Keele BF.

J Virol. 2014 Jul;88(14):8077-90. doi: 10.1128/JVI.01026-14. Epub 2014 May 7.

13.

Mutations in HIV-1 reverse transcriptase affect the errors made in a single cycle of viral replication.

Abram ME, Ferris AL, Das K, Quinoñes O, Shao W, Tuske S, Alvord WG, Arnold E, Hughes SH.

J Virol. 2014 Jul;88(13):7589-601. doi: 10.1128/JVI.00302-14. Epub 2014 Apr 23.

14.

Suppressive oligodeoxynucleotides reduce lung cancer susceptibility in mice with silicosis.

Bode C, Kinjo T, Alvord WG, Klinman DM.

Carcinogenesis. 2014 May;35(5):1078-83. doi: 10.1093/carcin/bgu005. Epub 2014 Jan 8.

15.

C/EBPγ suppresses senescence and inflammatory gene expression by heterodimerizing with C/EBPβ.

Huggins CJ, Malik R, Lee S, Salotti J, Thomas S, Martin N, Quiñones OA, Alvord WG, Olanich ME, Keller JR, Johnson PF.

Mol Cell Biol. 2013 Aug;33(16):3242-58. doi: 10.1128/MCB.01674-12. Epub 2013 Jun 17.

16.

Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection.

Tabb B, Morcock DR, Trubey CM, Quiñones OA, Hao XP, Smedley J, Macallister R, Piatak M Jr, Harris LD, Paiardini M, Silvestri G, Brenchley JM, Alvord WG, Lifson JD, Estes JD.

J Infect Dis. 2013 Mar 15;207(6):880-92. doi: 10.1093/infdis/jis643. Epub 2012 Oct 19.

17.

Molecular and organismal changes in offspring of male mice treated with chemical stressors.

Shiao YH, Leighty RM, Wang C, Ge X, Crawford EB, Spurrier JM, McCann SD, Fields JR, Fornwald L, Riffle L, Driver C, Kasprzak KS, Quiñones OA, Wilson RE, Travlos GS, Alvord WG, Anderson LM.

Environ Mol Mutagen. 2012 Jun;53(5):392-407. doi: 10.1002/em.21701.

PMID:
22674528
18.

3'UTR elements inhibit Ras-induced C/EBPβ post-translational activation and senescence in tumour cells.

Basu SK, Malik R, Huggins CJ, Lee S, Sebastian T, Sakchaisri K, Quiñones OA, Alvord WG, Johnson PF.

EMBO J. 2011 Jul 29;30(18):3714-28. doi: 10.1038/emboj.2011.250.

19.

Ontogeny-driven rDNA rearrangement, methylation, and transcription, and paternal influence.

Shiao YH, Leighty RM, Wang C, Ge X, Crawford EB, Spurrier JM, McCann SD, Fields JR, Fornwald L, Riffle L, Driver C, Quiñones OA, Wilson RE, Kasprzak KS, Travlos GS, Alvord WG, Anderson LM.

PLoS One. 2011;6(7):e22266. doi: 10.1371/journal.pone.0022266. Epub 2011 Jul 12.

20.

Residual NADPH oxidase and survival in chronic granulomatous disease.

Kuhns DB, Alvord WG, Heller T, Feld JJ, Pike KM, Marciano BE, Uzel G, DeRavin SS, Priel DA, Soule BP, Zarember KA, Malech HL, Holland SM, Gallin JI.

N Engl J Med. 2010 Dec 30;363(27):2600-10. doi: 10.1056/NEJMoa1007097.

21.

Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication.

Abram ME, Ferris AL, Shao W, Alvord WG, Hughes SH.

J Virol. 2010 Oct;84(19):9864-78. doi: 10.1128/JVI.00915-10. Epub 2010 Jul 21.

22.

Pharmacological analysis of Drosophila melanogaster gamma-secretase with respect to differential proteolysis of Notch and APP.

Groth C, Alvord WG, Quiñones OA, Fortini ME.

Mol Pharmacol. 2010 Apr;77(4):567-74. doi: 10.1124/mol.109.062471. Epub 2010 Jan 11.

23.

Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients.

Wei BR, Hoover SB, Ross MM, Zhou W, Meani F, Edwards JB, Spehalski EI, Risinger JI, Alvord WG, Quiñones OA, Belluco C, Martella L, Campagnutta E, Ravaggi A, Dai RM, Goldsmith PK, Woolard KD, Pecorelli S, Liotta LA, Petricoin EF, Simpson RM.

PLoS One. 2009 Oct 30;4(10):e7670. doi: 10.1371/journal.pone.0007670.

24.

An intergenic non-coding rRNA correlated with expression of the rRNA and frequency of an rRNA single nucleotide polymorphism in lung cancer cells.

Shiao YH, Lupascu ST, Gu YD, Kasprzak W, Hwang CJ, Fields JR, Leighty RM, Quiñones O, Shapiro BA, Alvord WG, Anderson LM.

PLoS One. 2009 Oct 19;4(10):e7505. doi: 10.1371/journal.pone.0007505.

25.

MTS dye based colorimetric CTLL-2 cell proliferation assay for product release and stability monitoring of interleukin-15: assay qualification, standardization and statistical analysis.

Soman G, Yang X, Jiang H, Giardina S, Vyas V, Mitra G, Yovandich J, Creekmore SP, Waldmann TA, Quiñones O, Alvord WG.

J Immunol Methods. 2009 Aug 31;348(1-2):83-94. doi: 10.1016/j.jim.2009.07.010. Epub 2009 Jul 30.

26.

Immunity to murine prostatic tumors: continuous provision of T-cell help prevents CD8 T-cell tolerance and activates tumor-infiltrating dendritic cells.

Shafer-Weaver KA, Watkins SK, Anderson MJ, Draper LJ, Malyguine A, Alvord WG, Greenberg NM, Hurwitz AA.

Cancer Res. 2009 Aug 1;69(15):6256-64. doi: 10.1158/0008-5472.CAN-08-4516. Epub 2009 Jul 21. Retraction in: Cancer Res. 2016 Apr 15;76(8):2490.

27.

Urothelial overexpression of insulin-like growth factor-1 increases susceptibility to p-cresidine-induced bladder carcinogenesis in transgenic mice.

Hursting SD, Perkins SN, Lavigne JA, Beltran L, Haines DC, Hill HL, Alvord WG, Barrett JC, DiGiovanni J.

Mol Carcinog. 2009 Aug;48(8):671-7. doi: 10.1002/mc.20548.

PMID:
19415693
28.
29.

Suppressive oligodeoxynucleotides inhibit silica-induced pulmonary inflammation.

Sato T, Shimosato T, Alvord WG, Klinman DM.

J Immunol. 2008 Jun 1;180(11):7648-54.

30.

Incomplete protection against simian immunodeficiency virus vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges.

Ambrose Z, Compton L, Piatak M Jr, Lu D, Alvord WG, Lubomirski MS, Hildreth JE, Lifson JD, Miller CJ, KewalRamani VN.

J Virol. 2008 Jul;82(13):6591-9. doi: 10.1128/JVI.02730-07. Epub 2008 Apr 23.

31.

Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.

Baba M, Furihata M, Hong SB, Tessarollo L, Haines DC, Southon E, Patel V, Igarashi P, Alvord WG, Leighty R, Yao M, Bernardo M, Ileva L, Choyke P, Warren MB, Zbar B, Linehan WM, Schmidt LS.

J Natl Cancer Inst. 2008 Jan 16;100(2):140-54. doi: 10.1093/jnci/djm288. Epub 2008 Jan 8.

32.

Rous sarcoma virus (RSV) integration in vivo: a CA dinucleotide is not required in U3, and RSV linear DNA does not autointegrate.

Oh J, Chang KW, Wierzchoslawski R, Alvord WG, Hughes SH.

J Virol. 2008 Jan;82(1):503-12. Epub 2007 Oct 24.

33.

The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists.

Huang DW, Sherman BT, Tan Q, Collins JR, Alvord WG, Roayaei J, Stephens R, Baseler MW, Lane HC, Lempicki RA.

Genome Biol. 2007;8(9):R183.

34.

A covalent inhibitor targeting an intermediate conformation of the fusogenic subunit of the HIV-1 envelope complex.

Jacobs A, Quraishi O, Huang X, Bousquet-Gagnon N, Nault G, Francella N, Alvord WG, Pham N, Soucy C, Robitaille M, Bridon D, Blumenthal R.

J Biol Chem. 2007 Nov 2;282(44):32406-13. Epub 2007 Aug 28.

35.

Replicating Ad-recombinants encoding non-myristoylated rather than wild-type HIV Nef elicit enhanced cellular immunity.

Peng B, Voltan R, Cristillo AD, Alvord WG, Davis-Warren A, Zhou Q, Murthy KK, Robert-Guroff M.

AIDS. 2006 Nov 14;20(17):2149-57.

PMID:
17086054
36.

Alternate polypurine tracts affect rous sarcoma virus integration in vivo.

Oh J, Chang KW, Alvord WG, Hughes SH.

J Virol. 2006 Oct;80(20):10281-4.

37.

Human immunodeficiency virus type 1 nucleocapsid zinc-finger mutations cause defects in reverse transcription and integration.

Thomas JA, Gagliardi TD, Alvord WG, Lubomirski M, Bosche WJ, Gorelick RJ.

Virology. 2006 Sep 15;353(1):41-51. Epub 2006 Jun 19.

38.

Combined IL-21 and low-dose IL-2 therapy induces anti-tumor immunity and long-term curative effects in a murine melanoma tumor model.

He H, Wisner P, Yang G, Hu HM, Haley D, Miller W, O'Hara A, Alvord WG, Clegg CH, Fox BA, Urba WJ, Walker EB.

J Transl Med. 2006 Jun 13;4:24.

39.

Modeling clinically heterogeneous presenilin mutations with transgenic Drosophila.

Seidner GA, Ye Y, Faraday MM, Alvord WG, Fortini ME.

Curr Biol. 2006 May 23;16(10):1026-33.

40.

Oral delivery of replication-competent adenovirus vectors is well tolerated by SIV- and SHIV-infected rhesus macaques.

Gómez-Román VR, Grimes GJ Jr, Potti GK, Peng B, Demberg T, Gravlin L, Treece J, Pal R, Lee EM, Alvord WG, Markham PD, Robert-Guroff M.

Vaccine. 2006 Jun 5;24(23):5064-72. Epub 2006 Mar 31.

PMID:
16621178
41.

Preconceptional fasting of fathers alters serum glucose in offspring of mice.

Anderson LM, Riffle L, Wilson R, Travlos GS, Lubomirski MS, Alvord WG.

Nutrition. 2006 Mar;22(3):327-31.

PMID:
16500559
42.

Combining mutations in HIV-1 reverse transcriptase with mutations in the HIV-1 polypurine tract affects RNase H cleavages involved in PPT utilization.

McWilliams MJ, Julias JG, Sarafianos SG, Alvord WG, Arnold E, Hughes SH.

Virology. 2006 May 10;348(2):378-88. Epub 2006 Feb 10.

44.

Enhanced cellular immunity to SIV Gag following co-administration of adenoviruses encoding wild-type or mutant HIV Tat and SIV Gag.

Zhao J, Voltan R, Peng B, Davis-Warren A, Kalyanaraman VS, Alvord WG, Aldrich K, Bernasconi D, Buttò S, Cafaro A, Ensoli B, Robert-Guroff M.

Virology. 2005 Nov 10;342(1):1-12. Epub 2005 Aug 18.

45.

Enhanced immunity and protective efficacy against SIVmac251 intrarectal challenge following ad-SIV priming by multiple mucosal routes and gp120 boosting in MPL-SE.

Pinczewski J, Zhao J, Malkevitch N, Patterson LJ, Aldrich K, Alvord WG, Robert-Guroff M.

Viral Immunol. 2005;18(1):236-43.

PMID:
15802969
46.

Inhibition of human neutrophil IL-8 production by hydrogen peroxide and dysregulation in chronic granulomatous disease.

Lekstrom-Himes JA, Kuhns DB, Alvord WG, Gallin JI.

J Immunol. 2005 Jan 1;174(1):411-7.

47.

Effects of mutations in the G tract of the human immunodeficiency virus type 1 polypurine tract on virus replication and RNase H cleavage.

Julias JG, McWilliams MJ, Sarafianos SG, Alvord WG, Arnold E, Hughes SH.

J Virol. 2004 Dec;78(23):13315-24.

48.

Evaluation of the safety, immunogenicity, and protective efficacy of whole inactivated simian immunodeficiency virus (SIV) vaccines with conformationally and functionally intact envelope glycoproteins.

Lifson JD, Rossio JL, Piatak M Jr, Bess J Jr, Chertova E, Schneider DK, Coalter VJ, Poore B, Kiser RF, Imming RJ, Scarzello AJ, Henderson LE, Alvord WG, Hirsch VM, Benveniste RE, Arthur LO.

AIDS Res Hum Retroviruses. 2004 Jul;20(7):772-87.

PMID:
15307924
49.

Mutations at position 184 of human immunodeficiency virus type-1 reverse transcriptase affect virus titer and viral DNA synthesis.

Julias JG, Boyer PL, McWilliams MJ, Alvord WG, Hughes SH.

Virology. 2004 Apr 25;322(1):13-21.

50.

Expressions of hepatic genes, especially IGF-binding protein-1, correlating with serum corticosterone in microarray analysis.

Cheng RY, Birely LA, Lum NL, Perella CM, Cherry JM, Bhat NK, Kasprzak KS, Powell DA, Alvord WG, Anderson LM.

J Mol Endocrinol. 2004 Feb;32(1):257-78.

PMID:
14766007

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