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Items: 12


Muscarinic Receptor Type-3 in Hypertension and Cholinergic-Adrenergic Crosstalk: Genetic Insights and Potential for New Antihypertensive Targets.

Alves-Lopes R, Neves KB, Touyz RM.

Can J Cardiol. 2019 May;35(5):555-557. doi: 10.1016/j.cjca.2019.02.003. Epub 2019 Feb 13. No abstract available.


PARP-1 (Poly[ADP-Ribose] Polymerase-1).

Alves-Lopes R, Touyz RM.

Hypertension. 2018 Nov;72(5):1087-1089. doi: 10.1161/HYPERTENSIONAHA.118.11830. No abstract available.


Chemerin receptor blockade improves vascular function in diabetic obese mice via redox-sensitive and Akt-dependent pathways.

Neves KB, Nguyen Dinh Cat A, Alves-Lopes R, Harvey KY, Costa RMD, Lobato NS, Montezano AC, Oliveira AM, Touyz RM, Tostes RC.

Am J Physiol Heart Circ Physiol. 2018 Dec 1;315(6):H1851-H1860. doi: 10.1152/ajpheart.00285.2018. Epub 2018 Sep 14.


Upregulation of Nrf2 and Decreased Redox Signaling Contribute to Renoprotective Effects of Chemerin Receptor Blockade in Diabetic Mice.

Neves KB, Montezano AC, Alves-Lopes R, Bruder-Nascimento T, Costa RM, Costa RS, Touyz RM, Tostes RC.

Int J Mol Sci. 2018 Aug 19;19(8). pii: E2454. doi: 10.3390/ijms19082454.


NADPH Oxidase 5 Is a Pro-Contractile Nox Isoform and a Point of Cross-Talk for Calcium and Redox Signaling-Implications in Vascular Function.

Montezano AC, De Lucca Camargo L, Persson P, Rios FJ, Harvey AP, Anagnostopoulou A, Palacios R, Gandara ACP, Alves-Lopes R, Neves KB, Dulak-Lis M, Holterman CE, de Oliveira PL, Graham D, Kennedy C, Touyz RM.

J Am Heart Assoc. 2018 Jun 15;7(12). pii: e009388. doi: 10.1161/JAHA.118.009388.


VEGFR (Vascular Endothelial Growth Factor Receptor) Inhibition Induces Cardiovascular Damage via Redox-Sensitive Processes.

Neves KB, Rios FJ, van der Mey L, Alves-Lopes R, Cameron AC, Volpe M, Montezano AC, Savoia C, Touyz RM.

Hypertension. 2018 Apr;71(4):638-647. doi: 10.1161/HYPERTENSIONAHA.117.10490. Epub 2018 Feb 26.


Vascular smooth muscle contraction in hypertension.

Touyz RM, Alves-Lopes R, Rios FJ, Camargo LL, Anagnostopoulou A, Arner A, Montezano AC.

Cardiovasc Res. 2018 Mar 15;114(4):529-539. doi: 10.1093/cvr/cvy023.


Glycosylation with O-linked β-N-acetylglucosamine induces vascular dysfunction via production of superoxide anion/reactive oxygen species.

Souza-Silva L, Alves-Lopes R, Silva Miguez J, Dela Justina V, Neves KB, Mestriner FL, Tostes RC, Giachini FR, Lima VV.

Can J Physiol Pharmacol. 2018 Mar;96(3):232-240. doi: 10.1139/cjpp-2017-0225. Epub 2017 Aug 9.


Genomic and non-genomic effects of androgens in the cardiovascular system: clinical implications.

Lucas-Herald AK, Alves-Lopes R, Montezano AC, Ahmed SF, Touyz RM.

Clin Sci (Lond). 2017 Jul 1;131(13):1405-1418. doi: 10.1042/CS20170090. Review.


NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular Damage.

Bruder-Nascimento T, Ferreira NS, Zanotto CZ, Ramalho F, Pequeno IO, Olivon VC, Neves KB, Alves-Lopes R, Campos E, Silva CA, Fazan R, Carlos D, Mestriner FL, Prado D, Pereira FV, Braga T, Luiz JP, Cau SB, Elias PC, Moreira AC, Câmara NO, Zamboni DS, Alves-Filho JC, Tostes RC.

Circulation. 2016 Dec 6;134(23):1866-1880. Epub 2016 Nov 1.


Internal Pudental Artery Dysfunction in Diabetes Mellitus Is Mediated by NOX1-Derived ROS-, Nrf2-, and Rho Kinase-Dependent Mechanisms.

Alves-Lopes R, Neves KB, Montezano AC, Harvey A, Carneiro FS, Touyz RM, Tostes RC.

Hypertension. 2016 Oct;68(4):1056-64. doi: 10.1161/HYPERTENSIONAHA.116.07518. Epub 2016 Aug 15.


Functional and structural changes in internal pudendal arteries underlie erectile dysfunction induced by androgen deprivation.

Alves-Lopes RU, Neves KB, Silva MA, Olivon VC, Ruginsk SG, Antunes-Rodrigues J, Ramalho LN, Tostes RC, Carneiro FS.

Asian J Androl. 2017 Sep-Oct;19(5):526-532. doi: 10.4103/1008-682X.173935.

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