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The Human Upper Respiratory Tract Epithelium Is Susceptible to Flaviviruses.

Vielle NJ, García-Nicolás O, Oliveira Esteves BI, Brügger M, Summerfield A, Alves MP.

Front Microbiol. 2019 Apr 16;10:811. doi: 10.3389/fmicb.2019.00811. eCollection 2019.


Role of structural ions on the dynamics of the Pseudomonas fluorescens 07A metalloprotease.

Polêto MD, Alves MP, Ligabue-Braun R, Eller MR, De Carvalho AF.

Food Chem. 2019 Jul 15;286:309-315. doi: 10.1016/j.foodchem.2019.01.204. Epub 2019 Feb 7.


Modulation of the unfolded protein response pathway as an antiviral approach in airway epithelial cells.

Schögler A, Caliaro O, Brügger M, Oliveira Esteves BI, Nita I, Gazdhar A, Geiser T, Alves MP.

Antiviral Res. 2019 Feb;162:44-50. doi: 10.1016/j.antiviral.2018.12.007. Epub 2018 Dec 11.


Research Models and Tools for the Identification of Antivirals and Therapeutics against Zika Virus Infection.

Alves MP, Vielle NJ, Thiel V, Pfaender S.

Viruses. 2018 Oct 30;10(11). pii: E593. doi: 10.3390/v10110593. Review.


Targeting of the Nasal Mucosa by Japanese Encephalitis Virus for Non-Vector-Borne Transmission.

García-Nicolás O, Braun RO, Milona P, Lewandowska M, Dijkman R, Alves MP, Summerfield A.

J Virol. 2018 Nov 27;92(24). pii: e01091-18. doi: 10.1128/JVI.01091-18. Print 2018 Dec 15.


Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells.

Tamò L, Hibaoui Y, Kallol S, Alves MP, Albrecht C, Hostettler KE, Feki A, Rougier JS, Abriel H, Knudsen L, Gazdhar A, Geiser T.

Am J Physiol Lung Cell Mol Physiol. 2018 Dec 1;315(6):L921-L932. doi: 10.1152/ajplung.00357.2017. Epub 2018 Sep 13.


The Small-Compound Inhibitor K22 Displays Broad Antiviral Activity against Different Members of the Family Flaviviridae and Offers Potential as a Panviral Inhibitor.

García-Nicolás O, V'kovski P, Vielle NJ, Ebert N, Züst R, Portmann J, Stalder H, Gaschen V, Vieyres G, Stoffel M, Schweizer M, Summerfield A, Engler O, Pietschmann T, Todt D, Alves MP, Thiel V, Pfaender S.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01206-18. doi: 10.1128/AAC.01206-18. Print 2018 Nov.


Silent infection of human dendritic cells by African and Asian strains of Zika virus.

Vielle NJ, Zumkehr B, García-Nicolás O, Blank F, Stojanov M, Musso D, Baud D, Summerfield A, Alves MP.

Sci Rep. 2018 Apr 3;8(1):5440. doi: 10.1038/s41598-018-23734-3.


Characterization of pediatric cystic fibrosis airway epithelial cell cultures at the air-liquid interface obtained by non-invasive nasal cytology brush sampling.

Schögler A, Blank F, Brügger M, Beyeler S, Tschanz SA, Regamey N, Casaulta C, Geiser T, Alves MP.

Respir Res. 2017 Dec 28;18(1):215. doi: 10.1186/s12931-017-0706-7.


Temperature modulates the production and activity of a metalloprotease from Pseudomonas fluorescens 07A in milk.

Alves MP, Salgado RL, Eller MR, Dias RS, Oliveira de Paula S, Fernandes de Carvalho A.

J Dairy Sci. 2018 Feb;101(2):992-999. doi: 10.3168/jds.2017-13238. Epub 2017 Dec 14.


Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry.

Behrendt P, Perin P, Menzel N, Banda D, Pfaender S, Alves MP, Thiel V, Meuleman P, Colpitts CC, Schang LM, Vondran FWR, Anggakusuma, Manns MP, Steinmann E, Pietschmann T.

Antiviral Res. 2017 Nov;147:19-28. doi: 10.1016/j.antiviral.2017.09.006. Epub 2017 Sep 18.


Anti-N-methyl-D-aspartate receptor encephalitis and Epstein-Barr virus: another tale on autoimmunity?

Danieli D, Moraes ACM, Alves MP, Dutra LA, Höftberger R, Barsottini OGP, Masruha MR.

Eur J Neurol. 2017 Aug;24(8):e46-e47. doi: 10.1111/ene.13332. No abstract available.


[Zika virus : from research to vaccine].

Vouga M, Alves MP, Eperon I, Eperon G, Rochat L, Sahli R, Musso D, Baud D.

Rev Med Suisse. 2016 Oct 26;12(536):1794-1798. French.


Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.

Siddharta A, Pfaender S, Vielle NJ, Dijkman R, Friesland M, Becker B, Yang J, Engelmann M, Todt D, Windisch MP, Brill FH, Steinmann J, Steinmann J, Becker S, Alves MP, Pietschmann T, Eickmann M, Thiel V, Steinmann E.

J Infect Dis. 2017 Mar 15;215(6):902-906. doi: 10.1093/infdis/jix046.


Comparison between the working environment of nurse managers and nursing assistants in the hospital context.

Santos JLGD, Erdmann AL, Peiter CC, Alves MP, Lima SBS, Backes VMS.

Rev Esc Enferm USP. 2017;51:e03300. doi: 10.1590/s1980-220x2017017103300. Epub 2018 Mar 15. English, Portuguese.


Zika virus: A new threat to human reproduction.

Baud D, Musso D, Vouga M, Alves MP, Vulliemoz N.

Am J Reprod Immunol. 2017 Feb;77(2). doi: 10.1111/aji.12614. Epub 2016 Dec 14. Review.


Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization.

Pfaender S, Vielle NJ, Ebert N, Steinmann E, Alves MP, Thiel V.

Virus Res. 2017 Jan 15;228:58-60. doi: 10.1016/j.virusres.2016.11.025. Epub 2016 Nov 23.


Harness shared data in international Zika registry.

Baud D, Gérardin P, Merriam A, Alves MP, Musso D, Genton B, Panchaud A.

BMJ. 2016 Oct 5;355:i5319. doi: 10.1136/bmj.i5319. No abstract available.


Characterization of a heat-resistant extracellular protease from Pseudomonas fluorescens 07A shows that low temperature treatments are more effective in deactivating its proteolytic activity.

Alves MP, Salgado RL, Eller MR, Vidigal PMP, Fernandes de Carvalho A.

J Dairy Sci. 2016 Oct;99(10):7842-7851. doi: 10.3168/jds.2016-11236. Epub 2016 Aug 4.


Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection.

Schögler A, Stokes AB, Casaulta C, Regamey N, Edwards MR, Johnston SL, Jung A, Moeller A, Geiser T, Alves MP.

J Cyst Fibros. 2016 May;15(3):332-9. doi: 10.1016/j.jcf.2015.10.013. Epub 2015 Nov 21.


Comparison of innate immune responses towards rhinovirus infection of primary nasal and bronchial epithelial cells.

Alves MP, Schögler A, Ebener S, Vielle NJ, Casaulta C, Jung A, Moeller A, Geiser T, Regamey N.

Respirology. 2016 Feb;21(2):304-12. doi: 10.1111/resp.12692. Epub 2015 Nov 26.


Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37.

Schögler A, Muster RJ, Kieninger E, Casaulta C, Tapparel C, Jung A, Moeller A, Geiser T, Regamey N, Alves MP.

Eur Respir J. 2016 Feb;47(2):520-30. doi: 10.1183/13993003.00665-2015. Epub 2015 Nov 19.


Human Rhinovirus Types and Association with Respiratory Symptoms During the First Year of Life.

Müller L, Mack I, Tapparel C, Kaiser L, Alves MP, Kieninger E, Frey U, Regamey N, Latzin P.

Pediatr Infect Dis J. 2015 Aug;34(8):907-9. doi: 10.1097/INF.0000000000000758.


Effect of the treatment with Achyrocline satureioides (free and nanocapsules essential oil) and diminazene aceturate on hematological and biochemical parameters in rats infected by Trypanosoma evansi.

Do Carmo GM, Baldissera MD, Vaucher RA, Rech VC, Oliveira CB, Sagrillo MR, Boligon AA, Athayde ML, Alves MP, França RT, Lopes ST, Schwertz CI, Mendes RE, Monteiro SG, Da Silva AS.

Exp Parasitol. 2015 Feb;149:39-46. doi: 10.1016/j.exppara.2014.12.005. Epub 2014 Dec 9.


Lactate dehydrogenase concentration in nasal wash fluid indicates severity of rhinovirus-induced wheezy bronchitis in preschool children.

Cangiano G, Proietti E, Kronig MN, Kieninger E, Sadeghi CD, Gorgievski M, Barbani MT, Midulla F, Tapparel C, Kaiser L, Alves MP, Regamey N.

Pediatr Infect Dis J. 2014 Dec;33(12):1285-7. doi: 10.1097/INF.0000000000000420.


Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells.

Schögler A, Kopf BS, Edwards MR, Johnston SL, Casaulta C, Kieninger E, Jung A, Moeller A, Geiser T, Regamey N, Alves MP.

Eur Respir J. 2015 Feb;45(2):428-39. doi: 10.1183/09031936.00102014. Epub 2014 Oct 30.


Meloxicam-loaded nanocapsules have antinociceptive and antiedematogenic effects in acute models of nociception.

Villalba BT, Ianiski FR, Wilhelm EA, Fernandes RS, Alves MP, Luchese C.

Life Sci. 2014 Oct 12;115(1-2):36-43. doi: 10.1016/j.lfs.2014.09.002. Epub 2014 Sep 18.


Current concepts: host-pathogen interactions in cystic fibrosis airways disease.

Tang AC, Turvey SE, Alves MP, Regamey N, Tümmler B, Hartl D.

Eur Respir Rev. 2014 Sep;23(133):320-32. doi: 10.1183/09059180.00006113. Review.


Preliminary study on tubuloglomerular dysfunction and evidence of renal inflammation in patients with visceral leishmaniasis.

Oliveira MJ, Silva GB Jr, Sampaio AM, Montenegro BL, Alves MP, Henn GA, Rocha HA, Meneses GC, Martins AM, Daher EF.

Am J Trop Med Hyg. 2014 Nov;91(5):908-11. doi: 10.4269/ajtmh.14-0167. Epub 2014 Aug 11.


Comparison of three different brushing techniques to isolate and culture primary nasal epithelial cells from human subjects.

Stokes AB, Kieninger E, Schögler A, Kopf BS, Casaulta C, Geiser T, Regamey N, Alves MP.

Exp Lung Res. 2014 Sep;40(7):327-32. doi: 10.3109/01902148.2014.925987. Epub 2014 Jul 24.


Treatment with essential oil of Achyrocline satureioides in rats infected with Trypanosoma evansi: relationship between protective effect and tissue damage.

Baldissera MD, Oliveira CB, Rech VC, Rezer JF, Sagrillo MR, Alves MP, da Silva AP, Leal DB, Boligon AA, Athayde ML, Da Silva AS, Mendes RE, Monteiro SG.

Pathol Res Pract. 2014 Dec;210(12):1068-74. doi: 10.1016/j.prp.2014.06.008. Epub 2014 Jun 24.


Proteinuria in adults with sickle-cell disease: the role of hydroxycarbamide(hydroxyurea) as a protective agent.

Silva Junior GB, Vieira AP, Couto Bem AX, Alves MP, Meneses GC, Martins AM, Araújo SM, Libório AV, Daher EF.

Int J Clin Pharm. 2014 Aug;36(4):766-70. doi: 10.1007/s11096-014-9955-4. Epub 2014 Jun 17.


Factors associated with thrombocytopenia in severe leptospirosis (Weil's disease).

Daher EF, Silva GB, Silveira CO, Falcão FS, Alves MP, Mota JA, Lima JB, Mota RM, Vieira AP, Pires Rda J, Libório AB.

Clinics (Sao Paulo). 2014 Feb;69(2):106-10. doi: 10.6061/clinics/2014(02)06.


Cetuximab plus platinum-based chemotherapy in head and neck squamous cell carcinoma: a retrospective study in a single comprehensive European cancer institution.

de Mello RA, Gerós S, Alves MP, Moreira F, Avezedo I, Dinis J.

PLoS One. 2014 Feb 6;9(2):e86697. doi: 10.1371/journal.pone.0086697. eCollection 2014.


Renal tubular dysfunction in sickle cell disease.

Silva Junior GB, Vieira AP, Couto Bem AX, Alves MP, Meneses GC, Martins AM, Sanches TR, Andrade LC, Seguro AC, Libório AB, Daher EF.

Kidney Blood Press Res. 2013;38(1):1-10. doi: 10.1159/000355748. Epub 2014 Jan 28.


UFV-P2 as a member of the Luz24likevirus genus: a new overview on comparative functional genome analyses of the LUZ24-like phages.

Eller MR, Vidigal PM, Salgado RL, Alves MP, Dias RS, da Silva CC, de Carvalho AF, Kropinski A, De Paula SO.

BMC Genomics. 2014 Jan 3;15:7. doi: 10.1186/1471-2164-15-7.


Diphenyl diselenide-loaded nanocapsules: preparation and biological distribution.

Giordani CF, de Souza D, Dornelles L, Nogueira CW, Alves MP, Prigol M, Rodrigues OE.

Appl Biochem Biotechnol. 2014 Jan;172(2):755-66.


Open Palm Technique in Dupuytren's Disease Treatment.

Malta MC, Alves MPT, Malta LMA.

Rev Bras Ortop. 2013 Aug 13;48(3):246-250. doi: 10.1016/j.rboe.2012.07.005. eCollection 2013 May-Jun.


Selective enumeration of propionibacteria in Emmental-type cheese using Petrifilm™ aerobic count plates added to lithium glycerol broth.

de Freitas R, Luiz LM, Alves MP, Valence-Bertel F, Nero LA, de Carvalho AF.

J Dairy Res. 2013 Aug;80(3):270-5. doi: 10.1017/S0022029913000198. Epub 2013 Apr 23.


Complete Genome Sequence of the Pseudomonas fluorescens Bacteriophage UFV-P2.

Eller MR, Salgado RL, Vidigal PM, Alves MP, Dias RS, de Oliveira LL, da Silva CC, de Carvalho AF, De Paula SO.

Genome Announc. 2013 Jan;1(1). pii: e00006-12. doi: 10.1128/genomeA.00006-12. Epub 2013 Jan 15.


Comparative analysis of pediatric and adult visceral leishmaniasis in Brazil.

Rocha NA, Oliveira MJ, Franco LF, Júnior GB, Alves MP, Sampaio AM, Montenegro BR, Vieira AP, Jacinto CN, Abreu KL, Daher EF.

Pediatr Infect Dis J. 2013 May;32(5):e182-5. doi: 10.1097/INF.0b013e3182814eae.


High rhinovirus burden in lower airways of children with cystic fibrosis.

Kieninger E, Singer F, Tapparel C, Alves MP, Latzin P, Tan HL, Bossley C, Casaulta C, Bush A, Davies JC, Kaiser L, Regamey N.

Chest. 2013 Mar;143(3):782-790. doi: 10.1378/chest.12-0954.


Natural lipid nanoparticles containing nimesulide: synthesis, characterization and in vivo antiedematogenic and antinociceptive activities.

Raffin RP, Lima A, Lorenzoni R, Antonow MB, Turra C, Alves MP, Fagan SB.

J Biomed Nanotechnol. 2012 Apr;8(2):309-15.


Protective effect of meloxicam-loaded nanocapsules against amyloid-β peptide-induced damage in mice.

Ianiski FR, Alves CB, Souza AC, Pinton S, Roman SS, Rhoden CR, Alves MP, Luchese C.

Behav Brain Res. 2012 Apr 21;230(1):100-7. doi: 10.1016/j.bbr.2012.01.055. Epub 2012 Feb 7.


Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells.

Vareille M, Kieninger E, Alves MP, Kopf BS, Möller A, Geiser T, Johnston SL, Edwards MR, Regamey N.

Thorax. 2012 Jun;67(6):517-25. doi: 10.1136/thoraxjnl-2011-200405. Epub 2012 Jan 2. Retraction in: Thorax. 2013 Sep;68(9):886.


Semi-solid topical formulations containing nimesulide-loaded nanocapsules showed in-vivo anti-inflammatory activity in chronic arthritis and fibrovascular tissue models.

Lenz QF, Guterres SS, Pohlmann A, Alves MP.

Inflamm Res. 2012 Apr;61(4):305-10. doi: 10.1007/s00011-011-0411-9. Epub 2011 Dec 18.


Lack of an exaggerated inflammatory response on virus infection in cystic fibrosis.

Kieninger E, Vareille M, Kopf BS, Blank F, Alves MP, Gisler FM, Latzin P, Casaulta C, Geiser T, Johnston SL, Edwards MR, Regamey N.

Eur Respir J. 2012 Feb;39(2):297-304. doi: 10.1183/09031936.00054511. Epub 2011 Jun 30.


Identification of the role of RIG-I, MDA-5 and TLR3 in sensing RNA viruses in porcine epithelial cells using lentivirus-driven RNA interference.

Hüsser L, Alves MP, Ruggli N, Summerfield A.

Virus Res. 2011 Jul;159(1):9-16. doi: 10.1016/j.virusres.2011.04.005. Epub 2011 Apr 22.


Porcine Flt3 ligand and its receptor: generation of dendritic cells and identification of a new marker for porcine dendritic cells.

Guzylack-Piriou L, Alves MP, McCullough KC, Summerfield A.

Dev Comp Immunol. 2010 Apr;34(4):455-64. doi: 10.1016/j.dci.2009.12.006. Epub 2009 Dec 21.


Innate immune defenses induced by CpG do not promote vaccine-induced protection against foot-and-mouth disease virus in pigs.

Alves MP, Guzylack-Piriou L, Juillard V, Audonnet JC, Doel T, Dawson H, Golde WT, Gerber H, Peduto N, McCullough KC, Summerfield A.

Clin Vaccine Immunol. 2009 Aug;16(8):1151-7. doi: 10.1128/CVI.00018-09. Epub 2009 Jun 24.

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