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Items: 9


Ranking the Contribution of Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphisms to Shaping the HLA-B*27 Peptidome.

Sanz-Bravo A, Alvarez-Navarro C, Martín-Esteban A, Barnea E, Admon A, López de Castro JA.

Mol Cell Proteomics. 2018 Jul;17(7):1308-1323. doi: 10.1074/mcp.RA117.000565. Epub 2018 Apr 9.


Molecular and pathogenic effects of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in MHC-I-associated inflammatory disorders: Towards a unifying view.

López de Castro JA, Alvarez-Navarro C, Brito A, Guasp P, Martín-Esteban A, Sanz-Bravo A.

Mol Immunol. 2016 Sep;77:193-204. doi: 10.1016/j.molimm.2016.08.005. Epub 2016 Aug 11. Review.


The Peptidome of Behçet's Disease-Associated HLA-B*51:01 Includes Two Subpeptidomes Differentially Shaped by Endoplasmic Reticulum Aminopeptidase 1.

Guasp P, Alvarez-Navarro C, Gomez-Molina P, Martín-Esteban A, Marcilla M, Barnea E, Admon A, López de Castro JA.

Arthritis Rheumatol. 2016 Feb;68(2):505-15. doi: 10.1002/art.39430. Erratum in: Arthritis Rheumatol. 2017 Mar;69(3):686.


Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphism Relevant to Inflammatory Disease Shapes the Peptidome of the Birdshot Chorioretinopathy-Associated HLA-A*29:02 Antigen.

Alvarez-Navarro C, Martín-Esteban A, Barnea E, Admon A, López de Castro JA.

Mol Cell Proteomics. 2015 Jul;14(7):1770-80. doi: 10.1074/mcp.M115.048959. Epub 2015 Apr 19.


Peptide handling by HLA-B27 subtypes influences their biological behavior, association with ankylosing spondylitis and susceptibility to endoplasmic reticulum aminopeptidase 1 (ERAP1).

García-Medel N, Sanz-Bravo A, Alvarez-Navarro C, Gómez-Molina P, Barnea E, Marcilla M, Admon A, de Castro JA.

Mol Cell Proteomics. 2014 Dec;13(12):3367-80. doi: 10.1074/mcp.M114.039214. Epub 2014 Sep 3.


ERAP1 structure, function and pathogenetic role in ankylosing spondylitis and other MHC-associated diseases.

Alvarez-Navarro C, López de Castro JA.

Mol Immunol. 2014 Jan;57(1):12-21. doi: 10.1016/j.molimm.2013.06.012. Epub 2013 Jul 31. Review.


Novel HLA-B27-restricted epitopes from Chlamydia trachomatis generated upon endogenous processing of bacterial proteins suggest a role of molecular mimicry in reactive arthritis.

Alvarez-Navarro C, Cragnolini JJ, Dos Santos HG, Barnea E, Admon A, Morreale A, López de Castro JA.

J Biol Chem. 2013 Sep 6;288(36):25810-25. doi: 10.1074/jbc.M113.493247. Epub 2013 Jul 18.


ERAP1 in ankylosing spondylitis: genetics, biology and pathogenetic role.

Alvarez-Navarro C, López de Castro JA.

Curr Opin Rheumatol. 2013 Jul;25(4):419-25. doi: 10.1097/BOR.0b013e328362042f. Review.


Functional interaction of the ankylosing spondylitis-associated endoplasmic reticulum aminopeptidase 1 polymorphism and HLA-B27 in vivo.

García-Medel N, Sanz-Bravo A, Van Nguyen D, Galocha B, Gómez-Molina P, Martín-Esteban A, Alvarez-Navarro C, de Castro JA.

Mol Cell Proteomics. 2012 Nov;11(11):1416-29. doi: 10.1074/mcp.M112.019588. Epub 2012 Aug 23.

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