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Items: 1 to 50 of 186

1.

Cannabinoid Attenuation of Intestinal Inflammation in Chronic SIV-Infected Rhesus Macaques Involves T Cell Modulation and Differential Expression of Micro-RNAs and Pro-inflammatory Genes.

Kumar V, Torben W, Mansfield J, Alvarez X, Vande Stouwe C, Li J, Byrareddy SN, Didier PJ, Pahar B, Molina PE, Mohan M.

Front Immunol. 2019 Apr 30;10:914. doi: 10.3389/fimmu.2019.00914. eCollection 2019.

2.

Shifting Dynamics of Intestinal Macrophages during Simian Immunodeficiency Virus Infection in Adult Rhesus Macaques.

Takahashi N, Sugimoto C, Allers C, Alvarez X, Kim WK, Didier ES, Kuroda MJ.

J Immunol. 2019 May 1;202(9):2682-2689. doi: 10.4049/jimmunol.1801457. Epub 2019 Mar 29.

PMID:
30926643
3.

Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection.

Liu L, Wei Q, Lin Q, Fang J, Wang H, Kwok H, Tang H, Nishiura K, Peng J, Tan Z, Wu T, Cheung KW, Chan KH, Alvarez X, Qin C, Lackner A, Perlman S, Yuen KY, Chen Z.

JCI Insight. 2019 Feb 21;4(4). pii: 123158. doi: 10.1172/jci.insight.123158. eCollection 2019 Feb 21.

4.

Comparative Analysis of Gammaherpesvirus Circular RNA Repertoires: Conserved and Unique Viral Circular RNAs.

Ungerleider NA, Jain V, Wang Y, Maness NJ, Blair RV, Alvarez X, Midkiff C, Kolson D, Bai S, Roberts C, Moss WN, Wang X, Serfecz J, Seddon M, Lehman T, Ma T, Dong Y, Renne R, Tibbetts SA, Flemington EK.

J Virol. 2019 Mar 5;93(6). pii: e01952-18. doi: 10.1128/JVI.01952-18. Print 2019 Mar 15.

PMID:
30567979
5.

Encephalitozoon cuniculi and Vittaforma corneae (Phylum Microsporidia) inhibit staurosporine-induced apoptosis in human THP-1 macrophages in vitro.

Sokolova YY, Bowers LC, Alvarez X, Didier ES.

Parasitology. 2019 Apr;146(5):569-579. doi: 10.1017/S0031182018001968. Epub 2018 Nov 29.

PMID:
30486909
6.

Beneficial Effects of Human Anti-Interleukin-15 Antibody in Gluten-Sensitive Rhesus Macaques with Celiac Disease.

Sestak K, Dufour JP, Liu DX, Rout N, Alvarez X, Blanchard J, Faldas A, Laine DJ, Clarke AW, Doyle AG.

Front Immunol. 2018 Jul 11;9:1603. doi: 10.3389/fimmu.2018.01603. eCollection 2018.

7.

Severity-Related Increase and Cognitive Correlates of Serum VEGF Levels in Alzheimer's Disease ApoE4 Carriers.

Alvarez XA, Alvarez I, Aleixandre M, Linares C, Muresanu D, Winter S, Moessler H.

J Alzheimers Dis. 2018;63(3):1003-1013. doi: 10.3233/JAD-160477.

PMID:
29710700
8.

High Turnover of Tissue Macrophages Contributes to Tuberculosis Reactivation in Simian Immunodeficiency Virus-Infected Rhesus Macaques.

Kuroda MJ, Sugimoto C, Cai Y, Merino KM, Mehra S, Araínga M, Roy CJ, Midkiff CC, Alvarez X, Didier ES, Kaushal D.

J Infect Dis. 2018 May 25;217(12):1865-1874. doi: 10.1093/infdis/jix625.

9.

In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis.

Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, Rengarajan J, Khader SA, Kaushal D, Mehra S.

Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):E62-E71. doi: 10.1073/pnas.1711373114. Epub 2017 Dec 18.

10.

Late Disseminated Lyme Disease: Associated Pathology and Spirochete Persistence Posttreatment in Rhesus Macaques.

Crossland NA, Alvarez X, Embers ME.

Am J Pathol. 2018 Mar;188(3):672-682. doi: 10.1016/j.ajpath.2017.11.005. Epub 2017 Dec 12.

11.

Correction for Sugimoto et al., "Critical Role for Monocytes/Macrophages in Rapid Progression to AIDS in Pediatric Simian Immunodeficiency Virus-Infected Rhesus Macaques".

Sugimoto C, Merino KM, Hasegawa A, Wang X, Alvarez XA, Wakao H, Mori K, Kim WK, Veazey RS, Didier ES, Kuroda MJ.

J Virol. 2017 Oct 27;91(22). pii: e01346-17. doi: 10.1128/JVI.01346-17. Print 2017 Nov 15. No abstract available.

12.

Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys.

Nelson CS, Cruz DV, Tran D, Bialas KM, Stamper L, Wu H, Gilbert M, Blair R, Alvarez X, Itell H, Chen M, Deshpande A, Chiuppesi F, Wussow F, Diamond DJ, Vandergrift N, Walter MR, Barry PA, Cohen-Wolkowiez M, Koelle K, Kaur A, Permar SR.

JCI Insight. 2017 Jul 6;2(13). pii: 94002. doi: 10.1172/jci.insight.94002. eCollection 2017 Jul 6.

13.

Critical Role for Monocytes/Macrophages in Rapid Progression to AIDS in Pediatric Simian Immunodeficiency Virus-Infected Rhesus Macaques.

Sugimoto C, Merino KM, Hasegawa A, Wang X, Alvarez XA, Wakao H, Mori K, Kim WK, Veazey RS, Didier ES, Kuroda MJ.

J Virol. 2017 Aug 10;91(17). pii: e00379-17. doi: 10.1128/JVI.00379-17. Print 2017 Sep 1. Erratum in: J Virol. 2017 Oct 27;91(22):.

14.

TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth.

Dowling DJ, van Haren SD, Scheid A, Bergelson I, Kim D, Mancuso CJ, Foppen W, Ozonoff A, Fresh L, Theriot TB, Lackner AA, Fichorova RN, Smirnov D, Vasilakos JP, Beaurline JM, Tomai MA, Midkiff CC, Alvarez X, Blanchard JL, Gilbert MH, Aye PP, Levy O.

JCI Insight. 2017 Mar 23;2(6):e91020. doi: 10.1172/jci.insight.91020.

15.

Hypoxia Sensing and Persistence Genes Are Expressed during the Intragranulomatous Survival of Mycobacterium tuberculosis.

Hudock TA, Foreman TW, Bandyopadhyay N, Gautam US, Veatch AV, LoBato DN, Gentry KM, Golden NA, Cavigli A, Mueller M, Hwang SA, Hunter RL, Alvarez X, Lackner AA, Bader JS, Mehra S, Kaushal D.

Am J Respir Cell Mol Biol. 2017 May;56(5):637-647. doi: 10.1165/rcmb.2016-0239OC.

16.

The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques.

McGary CS, Alvarez X, Harrington S, Cervasi B, Ryan ES, Iriele RI, Paganini S, Harper JL, Easley K, Silvestri G, Ansari AA, Lichterfeld M, Micci L, Paiardini M.

Mucosal Immunol. 2017 Jul;10(4):1082-1096. doi: 10.1038/mi.2016.116. Epub 2017 Jan 4.

17.

CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.

Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucşan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, Khader SA, Jacobs WR Jr, Kaushal D.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5636-44. doi: 10.1073/pnas.1611987113. Epub 2016 Sep 6.

18.

Freshwater algae competition and correlation between their growth and microcystin production.

Álvarez X, Valero E, Cancela Á, Sánchez Á.

Environ Sci Pollut Res Int. 2016 Nov;23(21):21577-21583. Epub 2016 Aug 12.

PMID:
27518397
19.

Supplementation of Reduced Gluten Barley Diet with Oral Prolyl Endopeptidase Effectively Abrogates Enteropathy-Associated Changes in Gluten-Sensitive Macaques.

Sestak K, Thwin H, Dufour J, Liu DX, Alvarez X, Laine D, Clarke A, Doyle A, Aye PP, Blanchard J, Moehs CP.

Nutrients. 2016 Jun 28;8(7). pii: E401. doi: 10.3390/nu8070401.

20.

Synergistic Increase of Serum BDNF in Alzheimer Patients Treated with Cerebrolysin and Donepezil: Association with Cognitive Improvement in ApoE4 Cases.

Alvarez XA, Alvarez I, Iglesias O, Crespo I, Figueroa J, Aleixandre M, Linares C, Granizo E, Garcia-Fantini M, Marey J, Masliah E, Winter S, Muresanu D, Moessler H.

Int J Neuropsychopharmacol. 2016 Apr 7. pii: pyw024. doi: 10.1093/ijnp/pyw024. [Epub ahead of print]

21.

The DEP-6D, a new preference-based measure to assess health states of dependency.

Rodríguez-Míguez E, Abellán-Perpiñán JM, Alvarez XC, González XM, Sampayo AR.

Soc Sci Med. 2016 Mar;153:210-9. doi: 10.1016/j.socscimed.2016.02.020. Epub 2016 Feb 16.

PMID:
26921836
22.

Pellets valorization of waste biomass harvested by coagulation of freshwater algae.

Cancela Á, Sánchez Á, Álvarez X, Jiménez A, Ortiz L, Valero E, Varela P.

Bioresour Technol. 2016 Mar;204:152-156. doi: 10.1016/j.biortech.2016.01.002. Epub 2016 Jan 7.

PMID:
26773958
23.

Spatiotemporal interplay of severe acute respiratory syndrome coronavirus and respiratory mucosal cells drives viral dissemination in rhesus macaques.

Liu L, Wei Q, Nishiura K, Peng J, Wang H, Midkiff C, Alvarez X, Qin C, Lackner A, Chen Z.

Mucosal Immunol. 2016 Jul;9(4):1089-101. doi: 10.1038/mi.2015.127. Epub 2015 Dec 9.

24.

Persistent Simian Immunodeficiency Virus Infection Drives Differentiation, Aberrant Accumulation, and Latent Infection of Germinal Center Follicular T Helper Cells.

Xu H, Wang X, Malam N, Aye PP, Alvarez X, Lackner AA, Veazey RS.

J Virol. 2015 Nov 25;90(3):1578-87. doi: 10.1128/JVI.02471-15. Print 2016 Feb 1.

25.

Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis.

Kaushal D, Foreman TW, Gautam US, Alvarez X, Adekambi T, Rangel-Moreno J, Golden NA, Johnson AM, Phillips BL, Ahsan MH, Russell-Lodrigue KE, Doyle LA, Roy CJ, Didier PJ, Blanchard JL, Rengarajan J, Lackner AA, Khader SA, Mehra S.

Nat Commun. 2015 Oct 13;6:8533. doi: 10.1038/ncomms9533.

26.

Preferential Destruction of Interstitial Macrophages over Alveolar Macrophages as a Cause of Pulmonary Disease in Simian Immunodeficiency Virus-Infected Rhesus Macaques.

Cai Y, Sugimoto C, Arainga M, Midkiff CC, Liu DX, Alvarez X, Lackner AA, Kim WK, Didier ES, Kuroda MJ.

J Immunol. 2015 Nov 15;195(10):4884-91. doi: 10.4049/jimmunol.1501194. Epub 2015 Oct 2.

27.

Simian Varicella Virus Is Present in Macrophages, Dendritic Cells, and T Cells in Lymph Nodes of Rhesus Macaques after Experimental Reactivation.

Traina-Dorge V, Doyle-Meyers LA, Sanford R, Manfredo J, Blackmon A, Wellish M, James S, Alvarez X, Midkiff C, Palmer BE, Deharo E, Gilden D, Mahalingam R.

J Virol. 2015 Oct;89(19):9817-24. doi: 10.1128/JVI.01324-15. Epub 2015 Jul 15.

28.

Androgen receptor splice variants circumvent AR blockade by microtubule-targeting agents.

Zhang G, Liu X, Li J, Ledet E, Alvarez X, Qi Y, Fu X, Sartor O, Dong Y, Zhang H.

Oncotarget. 2015 Sep 15;6(27):23358-71.

29.

SIV encephalitis lesions are composed of CD163(+) macrophages present in the central nervous system during early SIV infection and SIV-positive macrophages recruited terminally with AIDS.

Nowlin BT, Burdo TH, Midkiff CC, Salemi M, Alvarez X, Williams KC.

Am J Pathol. 2015 Jun;185(6):1649-65. doi: 10.1016/j.ajpath.2015.01.033. Epub 2015 May 8. Erratum in: Am J Pathol. 2017 Jun;187(6):1436.

30.

Harvesting green algae from eutrophic reservoir by electroflocculation and post-use for biodiesel production.

Valero E, Álvarez X, Cancela Á, Sánchez Á.

Bioresour Technol. 2015;187:255-262. doi: 10.1016/j.biortech.2015.03.138. Epub 2015 Apr 1.

PMID:
25863202
31.

Increased monocyte turnover is associated with interstitial macrophage accumulation and pulmonary tissue damage in SIV-infected rhesus macaques.

Cai Y, Sugimoto C, Liu DX, Midkiff CC, Alvarez X, Lackner AA, Kim WK, Didier ES, Kuroda MJ.

J Leukoc Biol. 2015 Jun;97(6):1147-53. doi: 10.1189/jlb.4A0914-441R. Epub 2015 Mar 16.

32.

Reduced expression of CD27 by collagenase treatment: implications for interpreting b cell data in tissues.

Shen C, Xu H, Alvarez X, Lackner AA, Veazey RS, Wang X.

PLoS One. 2015 Mar 10;10(3):e0116667. doi: 10.1371/journal.pone.0116667. eCollection 2015.

33.

The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence.

Mehra S, Foreman TW, Didier PJ, Ahsan MH, Hudock TA, Kissee R, Golden NA, Gautam US, Johnson AM, Alvarez X, Russell-Lodrigue KE, Doyle LA, Roy CJ, Niu T, Blanchard JL, Khader SA, Lackner AA, Sherman DR, Kaushal D.

Am J Respir Crit Care Med. 2015 May 15;191(10):1185-96. doi: 10.1164/rccm.201408-1502OC.

34.

Profound loss of intestinal Tregs in acutely SIV-infected neonatal macaques.

Wang X, Xu H, Shen C, Alvarez X, Liu D, Pahar B, Ratterree MS, Doyle-Meyers LA, Lackner AA, Veazey RS.

J Leukoc Biol. 2015 Feb;97(2):391-400. doi: 10.1189/jlb.4A0514-266RR. Epub 2014 Dec 9.

35.

Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques.

Mohan M, Kumar V, Lackner AA, Alvarez X.

J Immunol. 2015 Jan 1;194(1):291-306. doi: 10.4049/jimmunol.1401447. Epub 2014 Dec 1.

36.

CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells.

Micci L, Alvarez X, Iriele RI, Ortiz AM, Ryan ES, McGary CS, Deleage C, McAtee BB, He T, Apetrei C, Easley K, Pahwa S, Collman RG, Derdeyn CA, Davenport MP, Estes JD, Silvestri G, Lackner AA, Paiardini M.

PLoS Pathog. 2014 Oct 30;10(10):e1004467. doi: 10.1371/journal.ppat.1004467. eCollection 2014 Oct.

37.

DosS Is required for the complete virulence of mycobacterium tuberculosis in mice with classical granulomatous lesions.

Gautam US, McGillivray A, Mehra S, Didier PJ, Midkiff CC, Kissee RS, Golden NA, Alvarez X, Niu T, Rengarajan J, Sherman DR, Kaushal D.

Am J Respir Cell Mol Biol. 2015 Jun;52(6):708-16. doi: 10.1165/rcmb.2014-0230OC.

38.

Localization of productively infected cells in the spleen and Peyer's patches of rhesus macaques during acute infection with SIVmac239Δnef-enhanced green fluorescent protein.

Yang GB, Alexander L, Aye P, Alvarez X, Desrosiers RC, Lackner AA.

AIDS Res Hum Retroviruses. 2014 Aug;30(8):738-9. doi: 10.1089/AID.2014.0160. No abstract available.

39.

miR-190b is markedly upregulated in the intestine in response to simian immunodeficiency virus replication and partly regulates myotubularin-related protein-6 expression.

Mohan M, Chandra LC, Torben W, Aye PP, Alvarez X, Lackner AA.

J Immunol. 2014 Aug 1;193(3):1301-13. doi: 10.4049/jimmunol.1303479. Epub 2014 Jun 30.

40.

Role of TNF in the altered interaction of dormant Mycobacterium tuberculosis with host macrophages.

Gautam US, Mehra S, Ahsan MH, Alvarez X, Niu T, Kaushal D.

PLoS One. 2014 Apr 17;9(4):e95220. doi: 10.1371/journal.pone.0095220. eCollection 2014.

41.

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy.

Cao B, Qi Y, Zhang G, Xu D, Zhan Y, Alvarez X, Guo Z, Fu X, Plymate SR, Sartor O, Zhang H, Dong Y.

Oncotarget. 2014 Mar 30;5(6):1646-56.

42.

Detecting the simian immunodeficiency virus reservoir as viral DNA and RNA in situ simultaneously as a model to monitor viral latency.

Alvarez X, Midkiff C, Kuroda MJ, Mohan M, Lackner AA.

AIDS Res Hum Retroviruses. 2014 Mar;30(3):205-6. doi: 10.1089/aid.2014.0024. No abstract available.

43.

In vivo characterization of alveolar and interstitial lung macrophages in rhesus macaques: implications for understanding lung disease in humans.

Cai Y, Sugimoto C, Arainga M, Alvarez X, Didier ES, Kuroda MJ.

J Immunol. 2014 Mar 15;192(6):2821-9. doi: 10.4049/jimmunol.1302269. Epub 2014 Feb 17.

44.

Innate immune activation in the pathogenesis of a murine model of globoid cell leukodystrophy.

Snook ER, Fisher-Perkins JM, Sansing HA, Lee KM, Alvarez X, MacLean AG, Peterson KE, Lackner AA, Bunnell BA.

Am J Pathol. 2014 Feb;184(2):382-96. doi: 10.1016/j.ajpath.2013.10.011. Epub 2013 Dec 4.

45.

Tetherin upregulation in simian immunodeficiency virus-infected macaques.

Rahmberg AR, Neidermyer WJ Jr, Breed MW, Alvarez X, Midkiff CC, Piatak M Jr, Lifson JD, Evans DT.

J Virol. 2013 Dec;87(24):13917-21. doi: 10.1128/JVI.01757-13. Epub 2013 Oct 9.

46.

Kinetics of liver macrophages (Kupffer cells) in SIV-infected macaques.

Ahsan MH, Gill AF, Alvarez X, Lackner AA, Veazey RS.

Virology. 2013 Nov;446(1-2):77-85. doi: 10.1016/j.virol.2013.07.026. Epub 2013 Aug 19.

47.

A single amino acid mutation in the envelope cytoplasmic tail restores the ability of an attenuated simian immunodeficiency virus mutant to deplete mucosal CD4+ T cells.

Breed MW, Jordan AP, Aye PP, Sugimoto C, Alvarez X, Kuroda MJ, Pahar B, Keele BF, Hoxie JA, Lackner AA.

J Virol. 2013 Dec;87(23):13048-52. doi: 10.1128/JVI.02126-13. Epub 2013 Sep 11.

48.

Focused examination of the intestinal epithelium reveals transcriptional signatures consistent with disturbances in enterocyte maturation and differentiation during the course of SIV infection.

Mohan M, Kaushal D, Aye PP, Alvarez X, Veazey RS, Lackner AA.

PLoS One. 2013 Apr 9;8(4):e60122. doi: 10.1371/journal.pone.0060122. Print 2013.

49.

Granuloma correlates of protection against tuberculosis and mechanisms of immune modulation by Mycobacterium tuberculosis.

Mehra S, Alvarez X, Didier PJ, Doyle LA, Blanchard JL, Lackner AA, Kaushal D.

J Infect Dis. 2013 Apr;207(7):1115-27. doi: 10.1093/infdis/jis778. Epub 2012 Dec 18.

50.

Do subtoxic levels of chlorate influence the desiccation tolerance of Egeria densa?

Palma AT, Schwarz A, Henríquez LA, Alvarez X, Fariña JM, Lu Q.

Environ Toxicol Chem. 2013 Feb;32(2):417-22. doi: 10.1002/etc.2072. Epub 2012 Dec 31.

PMID:
23161751

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