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1.

Parkinsonism and spastic paraplegia type 7: Expanding the spectrum of mitochondrial Parkinsonism.

De la Casa-Fages B, Fernández-Eulate G, Gamez J, Barahona-Hernando R, Morís G, García-Barcina M, Infante J, Zulaica M, Fernández-Pelayo U, Muñoz-Oreja M, Urtasun M, Olaskoaga A, Zelaya V, Jericó I, Saez-Villaverde R, Catalina I, Sola E, Martínez-Sáez E, Pujol A, Ruiz M, Schlüter A, Spinazzola A, Muñoz-Blanco JL, Grandas F, Holt I, Álvarez V, López de Munaín A.

Mov Disord. 2019 Aug 21. doi: 10.1002/mds.27812. [Epub ahead of print]

PMID:
31433872
2.

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y; Alzheimer Disease Genetics Consortium (ADGC); European Alzheimer’s Disease Initiative (EADI); Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE); Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, O'Donovan MC, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA.

Nat Genet. 2019 Aug 15. doi: 10.1038/s41588-019-0495-7. [Epub ahead of print]

PMID:
31417202
3.

Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy.

Alosco ML, Stein TD, Tripodis Y, Chua AS, Kowall NW, Huber BR, Goldstein LE, Cantu RC, Katz DI, Palmisano JN, Martin B, Cherry JD, Mahar I, Killiany RJ, McClean MD, Au R, Alvarez V, Stern RA, Mez J, McKee AC.

JAMA Neurol. 2019 Aug 5. doi: 10.1001/jamaneurol.2019.2244. [Epub ahead of print]

PMID:
31380975
4.

Correction: Striatopallidal neurons control avoidance behavior in exploratory tasks.

LeBlanc KH, London TD, Szczot I, Bocarsly ME, Friend DM, Nguyen KP, Mengesha MM, Rubinstein M, Alvarez VA, Kravitz AV.

Mol Psychiatry. 2019 Jul 31. doi: 10.1038/s41380-019-0460-y. [Epub ahead of print]

PMID:
31366917
5.

A role for the CD38 rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, and functional MRI in humans.

Lee MR, Shin JH, Deschaine S, Daurio AM, Stangl BL, Yan J, Ramchandani VA, Schwandt ML, Grodin EN, Momenan R, Corral-Frias NS, Hariri AR, Bogdan R, Alvarez VA, Leggio L.

Am J Drug Alcohol Abuse. 2019 Jul 31:1-13. doi: 10.1080/00952990.2019.1638928. [Epub ahead of print]

PMID:
31365285
6.

Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties.

Rodenak-Kladniew B, Scioli Montoto S, Sbaraglini ML, Di Ianni M, Ruiz ME, Talevi A, Alvarez VA, Durán N, Castro GR, Islan GA.

Int J Pharm. 2019 Jul 26;569:118575. doi: 10.1016/j.ijpharm.2019.118575. [Epub ahead of print]

PMID:
31356956
7.

Potent and selective inhibitors for M32 metallocarboxypeptidases identified from high-throughput screening of anti-kinetoplastid chemical boxes.

Salas-Sarduy E, Landaburu LU, Carmona AK, Cazzulo JJ, Agüero F, Alvarez VE, Niemirowicz GT.

PLoS Negl Trop Dis. 2019 Jul 22;13(7):e0007560. doi: 10.1371/journal.pntd.0007560. eCollection 2019 Jul.

8.

Galectin-3 as a novel biotarget in cardiovascular alterations associated to development of severe aortic stenosis.

Arrieta V, Sádaba JR, Álvarez V, Rodríguez JA, López-Andrés N.

An Sist Sanit Navar. 2019 Jul 18;0(0):72347. doi: 10.23938/ASSN.0643. [Epub ahead of print] Review.

9.

Conditioned Serum Enhances the Chondrogenic and Immunomodulatory Behavior of Mesenchymal Stem Cells.

Blázquez R, Sánchez-Margallo FM, Reinecke J, Álvarez V, López E, Marinaro F, Casado JG.

Front Pharmacol. 2019 Jun 28;10:699. doi: 10.3389/fphar.2019.00699. eCollection 2019.

10.

Soluble ST2 promotes oxidative stress and inflammation in cardiac fibroblasts: an in vitro and in vivo study in aortic stenosis.

Matilla L, Ibarrola J, Arrieta V, Garcia-Peña A, Martinez-Martinez E, Sádaba R, Alvarez V, Navarro A, Fernández-Celis A, Gainza A, Santamaría E, Fernández-Irigoyen J, Bayes-Genis A, Rossignol P, López-Andrés N.

Clin Sci (Lond). 2019 Jul 17;133(14):1537-1548. doi: 10.1042/CS20190475. Print 2019 Jul 31.

PMID:
31285364
11.

Target-based screening of the Chagas box: setting up enzymatic assays to discover specific inhibitors across bioactive compounds.

Salas-Sarduy E, Niemirowicz GT, José Cazzulo J, Alvarez VE.

Curr Med Chem. 2019 Jul 5. doi: 10.2174/0929867326666190705160637. [Epub ahead of print]

PMID:
31284853
12.

Enhanced Properties of Chitosan Microparticles over Bulk Chitosan on the Modulation of the Auxin Signaling Pathway with Beneficial Impacts on Root Architecture in Plants.

Iglesias MJ, Colman SL, Terrile MC, París R, Martín-Saldaña S, Chevalier AA, Álvarez VA, Casalongué CA.

J Agric Food Chem. 2019 Jun 26;67(25):6911-6920. doi: 10.1021/acs.jafc.9b00907. Epub 2019 Jun 13.

PMID:
31194542
13.

Contact sport participation and chronic traumatic encephalopathy are associated with altered severity and distribution of cerebral amyloid angiopathy.

Standring OJ, Friedberg J, Tripodis Y, Chua AS, Cherry JD, Alvarez VE, Huber BR, Xia W, Mez J, Alosco ML, Nicks R, Mahar I, Pothast MJ, Gardner HM, Meng G, Palmisano JN, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, McKee AC, Stein TD.

Acta Neuropathol. 2019 Sep;138(3):401-413. doi: 10.1007/s00401-019-02031-x. Epub 2019 Jun 10.

PMID:
31183671
14.

Dose-dependent improvement of cardiac function in a swine model of acute myocardial infarction after intracoronary administration of allogeneic heart-derived cells.

Crisostomo V, Baez C, Abad JL, Sanchez B, Alvarez V, Rosado R, Gómez-Mauricio G, Gheysens O, Blanco-Blazquez V, Blazquez R, Torán JL, Casado JG, Aguilar S, Janssens S, Sánchez-Margallo FM, Rodriguez-Borlado L, Bernad A, Palacios I.

Stem Cell Res Ther. 2019 May 31;10(1):152. doi: 10.1186/s13287-019-1237-6.

15.

Naturally Avian Influenza Virus-Infected Wild Birds Are More Likely to Test Positive for Mycobacterium spp. and Salmonella spp.

Torrontegi O, Alvarez V, Hurtado A, Sevilla IA, Höfle U, Barral M.

Avian Dis. 2019 Mar 1;63(sp1):131-137. doi: 10.1637/11866-042518-Reg.1.

PMID:
31131569
16.

Striatal Cholinergic Interneurons Are a Novel Target of Corticotropin Releasing Factor.

Lemos JC, Shin JH, Alvarez VA.

J Neurosci. 2019 Jul 17;39(29):5647-5661. doi: 10.1523/JNEUROSCI.0479-19.2019. Epub 2019 May 20.

PMID:
31109960
17.

Bedaquiline overdose: A case report.

Telnov O, Alvarez V, Graglia E, Molfino L, du Cros P, Rich M.

Int J Infect Dis. 2019 Jul;84:138-140. doi: 10.1016/j.ijid.2019.03.035. Epub 2019 Apr 2.

18.

The Epistasis Project: A Multi-Cohort Study of the Effects of BDNF, DBH, and SORT1 Epistasis on Alzheimer's Disease Risk.

Belbin O, Morgan K, Medway C, Warden D, Cortina-Borja M, van Duijn CM, Adams HHH, Frank-Garcia A, Brookes K, Sánchez-Juan P, Alvarez V, Heun R, Kölsch H, Coto E, Kehoe PG, Rodriguez-Rodriguez E, Bullido MJ, Ikram MA, Smith AD, Lehmann DJ.

J Alzheimers Dis. 2019;68(4):1535-1547. doi: 10.3233/JAD-181116.

PMID:
30909233
19.

Identification of very early inflammatory markers in a porcine myocardial infarction model.

López E, Sánchez-Margallo FM, Álvarez V, Blázquez R, Marinaro F, Abad A, Martín H, Báez C, Blanco V, Crisóstomo V, Casado JG.

BMC Vet Res. 2019 Mar 12;15(1):91. doi: 10.1186/s12917-019-1837-5.

20.

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y, Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, C O'Donovan M, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA; Alzheimer Disease Genetics Consortium (ADGC),; European Alzheimer’s Disease Initiative (EADI),; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE),; Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES),.

Nat Genet. 2019 Mar;51(3):414-430. doi: 10.1038/s41588-019-0358-2. Epub 2019 Feb 28. Erratum in: Nat Genet. 2019 Aug 15;:.

PMID:
30820047
21.

Seeding variability of different alpha synuclein strains in synucleinopathies.

Candelise N, Schmitz M, Llorens F, Villar-Piqué A, Cramm M, Thom T, da Silva Correia SM, da Cunha JEG, Möbius W, Outeiro TF, Álvarez VG, Banchelli M, D'Andrea C, de Angelis M, Zafar S, Rabano A, Matteini P, Zerr I.

Ann Neurol. 2019 May;85(5):691-703. doi: 10.1002/ana.25446. Epub 2019 Mar 27.

PMID:
30805957
22.

New approaches to identification and characterization of tioconazole in raw material and in pharmaceutical dosage forms.

Calvo NL, Alvarez VA, Lamas MC, Leonardi D.

J Pharm Anal. 2019 Feb;9(1):40-48. doi: 10.1016/j.jpha.2018.11.006. Epub 2018 Nov 23.

23.

Long-term avian influenza virus epidemiology in a small Spanish wetland ecosystem is driven by the breeding Anseriformes community.

Torrontegi O, Alvarez V, Acevedo P, Gerrikagoitia X, Höfle U, Barral M.

Vet Res. 2019 Jan 17;50(1):4. doi: 10.1186/s13567-019-0623-5.

24.

Extracellular vesicles derived from endometrial human mesenchymal stem cells enhance embryo yield and quality in an aged murine model†.

Marinaro F, Macías-García B, Sánchez-Margallo FM, Blázquez R, Álvarez V, Matilla E, Hernández N, Gómez-Serrano M, Jorge I, Vázquez J, González-Fernández L, Pericuesta E, Gutiérrez-Adán A, Casado JG.

Biol Reprod. 2019 May 1;100(5):1180-1192. doi: 10.1093/biolre/ioy263.

PMID:
30596891
25.

Standardization in laboratory medicine: Two years' experience from category 1 EQA programs in Spain.

Ricós C, Perich C, Boned B, González-Lao E, Diaz-Garzón J, Ventura M, Bullich S, Corte Z, Minchinela J, Marques F, Simón M, Alvarez V, García-Lario JV, Fernández-Fernández P, Fernández-Calle P.

Biochem Med (Zagreb). 2019 Feb 15;29(1):010701. doi: 10.11613/BM.2019.010701. Epub 2018 Dec 15.

26.

Ischemia-reperfusion injury in a rat microvascular skin free flap model: A histological, genetic, and blood flow study.

Ballestín A, Casado JG, Abellán E, Vela FJ, Álvarez V, Usón A, López E, Marinaro F, Blázquez R, Sánchez-Margallo FM.

PLoS One. 2018 Dec 27;13(12):e0209624. doi: 10.1371/journal.pone.0209624. eCollection 2018.

27.

Follow-up and results in patients with differentiated thyroid carcinoma in Castilla-La Mancha (2001-2015). The CADIT-CAM study.

Sastre Marcos J, Aznar S, Álvarez V, Torres B, Delgado M, González J, Quiroga I.

Endocrinol Diabetes Nutr. 2019 Mar;66(3):164-172. doi: 10.1016/j.endinu.2018.10.005. Epub 2018 Dec 21. English, Spanish.

PMID:
30583968
28.

HTT gene intermediate alleles in neurodegeneration: evidence for association with Alzheimer's disease.

Menéndez-González M, Clarimón J, Rosas-Allende I, Blázquez M, San Martín ES, García-Fernández C, Lleó A, Dols-Icardo O, Illán-Gala I, Morís G, Ribacoba R, Álvarez V, Martínez C.

Neurobiol Aging. 2019 Apr;76:215.e9-215.e14. doi: 10.1016/j.neurobiolaging.2018.11.014. Epub 2018 Nov 28.

PMID:
30583877
29.

Impact of gum arabic and sodium alginate and their interactions with whey protein aggregates on bio-based films characteristics.

Erben M, Pérez AA, Osella CA, Alvarez VA, Santiago LG.

Int J Biol Macromol. 2019 Mar 15;125:999-1007. doi: 10.1016/j.ijbiomac.2018.12.131. Epub 2018 Dec 17.

PMID:
30572052
30.

Cortical degeneration in chronic traumatic encephalopathy and Alzheimer's disease neuropathologic change.

Armstrong RA, McKee AC, Stein TD, Alvarez VE, Cairns NJ.

Neurol Sci. 2019 Mar;40(3):529-533. doi: 10.1007/s10072-018-3686-6. Epub 2018 Dec 18.

31.

Co-occurrence of chronic traumatic encephalopathy and prion disease.

Nemani SK, Notari S, Cali I, Alvarez VE, Kofskey D, Cohen M, Stern RA, Appleby B, Abrams J, Schonberger L, McKee A, Gambetti P.

Acta Neuropathol Commun. 2018 Dec 18;6(1):140. doi: 10.1186/s40478-018-0643-9.

32.

Chitosan-hydroxypropyl methylcellulose tioconazole films: A promising alternative dosage form for the treatment of vaginal candidiasis.

Calvo NL, Svetaz LA, Alvarez VA, Quiroga AD, Lamas MC, Leonardi D.

Int J Pharm. 2019 Feb 10;556:181-191. doi: 10.1016/j.ijpharm.2018.12.011. Epub 2018 Dec 12.

PMID:
30553009
33.

D1 receptor hypersensitivity in mice with low striatal D2 receptors facilitates select cocaine behaviors.

Dobbs LK, Kaplan AR, Bock R, Phamluong K, Shin JH, Bocarsly ME, Eberhart L, Ron D, Alvarez VA.

Neuropsychopharmacology. 2019 Mar;44(4):805-816. doi: 10.1038/s41386-018-0286-3. Epub 2018 Dec 1.

34.

Meshes in a mess: Mesenchymal stem cell-based therapies for soft tissue reinforcement.

Marinaro F, Sánchez-Margallo FM, Álvarez V, López E, Tarazona R, Brun MV, Blázquez R, Casado JG.

Acta Biomater. 2019 Feb;85:60-74. doi: 10.1016/j.actbio.2018.11.042. Epub 2018 Nov 27. Review.

PMID:
30500445
35.

Altered hematological, biochemical and immunological parameters as predictive biomarkers of severity in experimental myocardial infarction.

Blázquez R, Álvarez V, Antequera-Barroso JA, Báez-Díaz C, Blanco V, Maestre J, Moreno-Lobato B, López E, Marinaro F, Casado JG, Crisóstomo V, Sánchez-Margallo FM.

Vet Immunol Immunopathol. 2018 Nov;205:49-57. doi: 10.1016/j.vetimm.2018.10.007. Epub 2018 Oct 24.

PMID:
30459001
36.

In vitro and in vivo evaluation of desmopressin-loaded poly(D,L-lactic-co-glycolic acid) nanoparticles for its potential use in cancer treatment.

Chevalier MT, Garona J, Sobol NT, Farina HG, Alonso DF, Álvarez VA.

Nanomedicine (Lond). 2018 Nov;13(22):2835-2849. doi: 10.2217/nnm-2018-0065. Epub 2018 Nov 15.

PMID:
30430901
37.

Variation in TMEM106B in chronic traumatic encephalopathy.

Cherry JD, Mez J, Crary JF, Tripodis Y, Alvarez VE, Mahar I, Huber BR, Alosco ML, Nicks R, Abdolmohammadi B, Kiernan PT, Evers L, Svirsky S, Babcock K, Gardner HM, Meng G, Nowinski CJ, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, Farrer LA, McKee AC, Stein TD.

Acta Neuropathol Commun. 2018 Nov 4;6(1):115. doi: 10.1186/s40478-018-0619-9.

38.

Reduced interleukin 1A gene expression in the dorsolateral prefrontal cortex of individuals with PTSD and depression.

Morrison FG, Miller MW, Wolf EJ, Logue MW, Maniates H, Kwasnik D, Cherry JD, Svirsky S, Restaino A, Hildebrandt A, Aytan N, Stein TD, Alvarez VE, McKee AC; Traumatic Stress Brain Study Group, Huber BR.

Neurosci Lett. 2019 Jan 23;692:204-209. doi: 10.1016/j.neulet.2018.10.027. Epub 2018 Oct 23.

PMID:
30366016
39.

Simplified inducible system for Trypanosoma brucei.

Niemirowicz GT, Cazzulo JJ, Álvarez VE, Bouvier LA.

PLoS One. 2018 Oct 11;13(10):e0205527. doi: 10.1371/journal.pone.0205527. eCollection 2018.

40.

Chronic Traumatic Encephalopathy Within an Amyotrophic Lateral Sclerosis Brain Bank Cohort.

Walt GS, Burris HM, Brady CB, Spencer KR, Alvarez VE, Huber BR, Guilderson L, Abdul Rauf N, Collins D, Singh T, Mathias R, Averill JG, Walker SE, Robey I, McKee AC, Kowall NW, Stein TD.

J Neuropathol Exp Neurol. 2018 Dec 1;77(12):1091-1100. doi: 10.1093/jnen/nly092.

PMID:
30299493
41.

Extracellular vesicles derived from endometrial human mesenchymal stem cells improve IVF outcome in an aged murine model.

Marinaro F, Pericuesta E, Sánchez-Margallo FM, Casado JG, Álvarez V, Matilla E, Hernández N, Blázquez R, González-Fernández L, Gutiérrez-Adán A, Macías-García B.

Reprod Domest Anim. 2018 Sep;53 Suppl 2:46-49. doi: 10.1111/rda.13314.

PMID:
30238659
42.

Composite Microparticles Based on Natural Mucoadhesive Polymers with Promising Structural Properties to Protect and Improve the Antifungal Activity of Miconazole Nitrate.

Tejada G, Lamas MC, Sortino M, Alvarez VA, Leonardi D.

AAPS PharmSciTech. 2018 Nov;19(8):3712-3722. doi: 10.1208/s12249-018-1175-0. Epub 2018 Sep 20.

PMID:
30238304
43.

Genomic analysis of the first isolate of KPC-2-producing Klebsiella pneumoniae from Uruguay.

Álvarez VE, Campos J, Galiana A, Borthagaray G, Centrón D, Márquez Villalba C.

J Glob Antimicrob Resist. 2018 Dec;15:109-110. doi: 10.1016/j.jgar.2018.09.001. Epub 2018 Sep 10.

PMID:
30213719
44.

Astrocytic degeneration in chronic traumatic encephalopathy.

Hsu ET, Gangolli M, Su S, Holleran L, Stein TD, Alvarez VE, McKee AC, Schmidt RE, Brody DL.

Acta Neuropathol. 2018 Dec;136(6):955-972. doi: 10.1007/s00401-018-1902-3. Epub 2018 Sep 7.

PMID:
30194648
45.

Salicylic acid loaded chitosan microparticles applied to lettuce seedlings: Recycling shrimp fishing industry waste.

Martin-Saldaña S, Chevalier MT, Iglesias MJ, Colman SL, Casalongué CA, Álvarez VA, Chevalier AA.

Carbohydr Polym. 2018 Nov 15;200:321-331. doi: 10.1016/j.carbpol.2018.08.019. Epub 2018 Aug 6.

PMID:
30177172
46.

Does continuous EEG influence prognosis in patients after cardiac arrest?

Fatuzzo D, Beuchat I, Alvarez V, Novy J, Oddo M, Rossetti AO.

Resuscitation. 2018 Nov;132:29-32. doi: 10.1016/j.resuscitation.2018.08.023. Epub 2018 Aug 25.

PMID:
30153468
47.

The immunomodulatory activity of extracellular vesicles derived from endometrial mesenchymal stem cells on CD4+ T cells is partially mediated by TGFbeta.

Álvarez V, Sánchez-Margallo FM, Macías-García B, Gómez-Serrano M, Jorge I, Vázquez J, Blázquez R, Casado JG.

J Tissue Eng Regen Med. 2018 Oct;12(10):2088-2098. doi: 10.1002/term.2743. Epub 2018 Aug 19.

PMID:
30058282
48.

Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports.

Adams JW, Alvarez VE, Mez J, Huber BR, Tripodis Y, Xia W, Meng G, Kubilus CA, Cormier K, Kiernan PT, Daneshvar DH, Chua AS, Svirsky S, Nicks R, Abdolmohammadi B, Evers L, Solomon TM, Cherry JD, Aytan N, Mahar I, Devine S, Auerbach S, Alosco ML, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, Au R, McKee AC, Stein TD.

J Neuropathol Exp Neurol. 2018 Sep 1;77(9):757-768. doi: 10.1093/jnen/nly065.

49.

Effect of drug incorporation technique and polymer combination on the performance of biopolymeric antifungal buccal films.

Tejada G, Lamas MC, Svetaz L, Salomón CJ, Alvarez VA, Leonardi D.

Int J Pharm. 2018 Sep 5;548(1):431-442. doi: 10.1016/j.ijpharm.2018.07.023. Epub 2018 Jul 6.

PMID:
30008423
50.

Bacterial cellulose hydrogel loaded with lipid nanoparticles for localized cancer treatment.

Cacicedo ML, Islan GA, León IE, Álvarez VA, Chourpa I, Allard-Vannier E, García-Aranda N, Díaz-Riascos ZV, Fernández Y, Schwartz S Jr, Abasolo I, Castro GR.

Colloids Surf B Biointerfaces. 2018 Oct 1;170:596-608. doi: 10.1016/j.colsurfb.2018.06.056. Epub 2018 Jun 26.

PMID:
29975908

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