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Items: 23


The Biology of the Nuclear Envelope and Its Implications in Cancer Biology.

Alvarado-Kristensson M, Rosselló CA.

Int J Mol Sci. 2019 May 27;20(10). pii: E2586. doi: 10.3390/ijms20102586. Review.


The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization.

Lindström L, Li T, Malycheva D, Kancharla A, Nilsson H, Vishnu N, Mulder H, Johansson M, Rosselló CA, Alvarado-Kristensson M.

Commun Biol. 2018 May 3;1:37. doi: 10.1038/s42003-018-0037-3. eCollection 2018.


Helicobacter pylori Outer Membrane Vesicles Protect the Pathogen From Reactive Oxygen Species of the Respiratory Burst.

Lekmeechai S, Su YC, Brant M, Alvarado-Kristensson M, Vallström A, Obi I, Arnqvist A, Riesbeck K.

Front Microbiol. 2018 Sep 7;9:1837. doi: 10.3389/fmicb.2018.01837. eCollection 2018.


γ-tubulin as a signal-transducing molecule and meshwork with therapeutic potential.

Alvarado-Kristensson M.

Signal Transduct Target Ther. 2018 Sep 14;3:24. doi: 10.1038/s41392-018-0021-x. eCollection 2018. Review.


A simple and fast method for fixation of cultured cell lines that preserves cellular structures containing gamma-tubulin.

Alvarado-Kristensson M.

MethodsX. 2018 Mar 3;5:227-233. doi: 10.1016/j.mex.2018.02.003. eCollection 2018.


Characterization of gamma-tubulin filaments in mammalian cells.

Lindström L, Alvarado-Kristensson M.

Biochim Biophys Acta Mol Cell Res. 2018 Jan;1865(1):158-171. doi: 10.1016/j.bbamcr.2017.10.008. Epub 2017 Oct 16.


A potential anti-tumor effect of leukotriene C4 through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells.

Mehdawi LM, Satapathy SR, Gustafsson A, Lundholm K, Alvarado-Kristensson M, Sjölander A.

Oncotarget. 2017 May 23;8(21):35033-35047. doi: 10.18632/oncotarget.16591.


Gamma-tubulin coordinates nuclear envelope assembly around chromatin.

Rosselló CA, Lindström L, Glindre J, Eklund G, Alvarado-Kristensson M.

Heliyon. 2016 Sep 24;2(9):e00166. eCollection 2016 Sep.


The Respiratory Pathogen Moraxella catarrhalis Targets Collagen for Maximal Adherence to Host Tissues.

Singh B, Alvarado-Kristensson M, Johansson M, Hallgren O, Westergren-Thorsson G, Mörgelin M, Riesbeck K.

MBio. 2016 Mar 22;7(2):e00066. doi: 10.1128/mBio.00066-16.


Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors.

Lindström L, Villoutreix BO, Lehn S, Hellsten R, Nilsson E, Crneta E, Olsson R, Alvarado-Kristensson M.

Mol Cancer Res. 2015 Jul;13(7):1073-82. doi: 10.1158/1541-7786.MCR-15-0063-T. Epub 2015 May 1.


The nuclear localization of γ-tubulin is regulated by SadB-mediated phosphorylation.

Eklund G, Lang S, Glindre J, Ehlén Å, Alvarado-Kristensson M.

J Biol Chem. 2014 Aug 1;289(31):21360-73. doi: 10.1074/jbc.M114.562389. Epub 2014 Jun 18.


Tumors with nonfunctional retinoblastoma protein are killed by reduced γ-tubulin levels.

Ehlén Å, Rosselló CA, von Stedingk K, Höög G, Nilsson E, Pettersson HM, Jirström K, Alvarado-Kristensson M.

J Biol Chem. 2012 May 18;287(21):17241-7. doi: 10.1074/jbc.M112.357038. Epub 2012 Apr 6.


RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer.

Ehlén Å, Nodin B, Rexhepaj E, Brändstedt J, Uhlén M, Alvarado-Kristensson M, Pontén F, Brennan DJ, Jirström K.

Transl Oncol. 2011 Aug;4(4):212-21. Epub 2011 Aug 1.


Nuclear localization of γ-tubulin affects E2F transcriptional activity and S-phase progression.

Höög G, Zarrizi R, von Stedingk K, Jonsson K, Alvarado-Kristensson M.

FASEB J. 2011 Nov;25(11):3815-27. doi: 10.1096/fj.11-187484. Epub 2011 Jul 25.


Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.

Ehlén A, Brennan DJ, Nodin B, O'Connor DP, Eberhard J, Alvarado-Kristensson M, Jeffrey IB, Manjer J, Brändstedt J, Uhlén M, Pontén F, Jirström K.

J Transl Med. 2010 Aug 20;8:78. doi: 10.1186/1479-5876-8-78.


SADB kinases license centrosome replication.

Carrera AC, Alvarado-Kristensson M.

Cell Cycle. 2009 Dec 15;8(24):4005-6. Epub 2009 Dec 25. No abstract available.


SADB phosphorylation of gamma-tubulin regulates centrosome duplication.

Alvarado-Kristensson M, Rodríguez MJ, Silió V, Valpuesta JM, Carrera AC.

Nat Cell Biol. 2009 Sep;11(9):1081-92. doi: 10.1038/ncb1921. Epub 2009 Aug 2.


PTEN regulation, a novel function for the p85 subunit of phosphoinositide 3-kinase.

Barber DF, Alvarado-Kristensson M, González-García A, Pulido R, Carrera AC.

Sci STKE. 2006 Nov 21;2006(362):pe49.


Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3.

Alvarado-Kristensson M, Andersson T.

J Biol Chem. 2005 Feb 18;280(7):6238-44. Epub 2004 Nov 29.


p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils.

Alvarado-Kristensson M, Melander F, Leandersson K, Rönnstrand L, Wernstedt C, Andersson T.

J Exp Med. 2004 Feb 16;199(4):449-58.


Sphingosine 1-phosphate antagonizes human neutrophil apoptosis via p38 mitogen-activated protein kinase.

Chihab R, Pörn-Ares MI, Alvarado-Kristensson M, Andersson T.

Cell Mol Life Sci. 2003 Apr;60(4):776-85.


p38 Mitogen-activated protein kinase and phosphatidylinositol 3-kinase activities have opposite effects on human neutrophil apoptosis.

Alvarado-Kristensson M, Porn-Ares MI, Grethe S, Smith D, Zheng L, Andersson T.

FASEB J. 2002 Jan;16(1):129-31. Epub 2001 Nov 29.


Fas-Induced Apoptosis of Human Neutrophils is Promoted by Phosphatidyl Inositol 3-Kinase but Suppressed by P38-MAPK Activity.

Alvarado-Kristensson M, Poumlrn-Ares MI, Grethe S, Smith D, Zheng L, Andersson T.

ScientificWorldJournal. 2001 Oct 23;1:116. doi: 10.1100/tsw.2001.222. eCollection 2001. No abstract available.

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